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Research | 8 January 2021 | Open
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression
- Guojun Hou
- , Isaac T. W. Harley
- , Xiaoming Lu
- , Tian Zhou
- , Ning Xu
- , Chao Yao
- , Yuting Qin
- , Ye Ouyang
- , Jianyang Ma
- , Xinyi Zhu
- , Xiang Yu
- , Hong Xu
- , Dai Dai
- , Huihua Ding
- , Zhihua Yin
- , Zhizhong Ye
- , Jun Deng
- , Mi Zhou
- , Yuanjia Tang
- , Bahram Namjou
- , Ya Guo
- , Matthew T. Weirauch
- , Leah C. Kottyan
- , John B. Harley
- & Nan Shen
Nature Communications 12 , 1–19

Rights & permissionsfor article SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression . Opens in a new window.
Amendments and Corrections | 11 June 2020
Author Correction: Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma
- Dan Liao
- , Li Zhong
- , Junqiang Yin
- , Cuiling Zeng
- , Xin Wang
- , Xingchuan Huang
- , Jinna Chen
- , Hong Zhang
- , Ruhua Zhang
- , Xin-Yuan Guan
- , Xintao Shuai
- , Jianhua Sui
- , Song Gao
- , Wuguo Deng
- , Yi-Xin Zeng
- , Jing-Nan Shen
- , Jian Chen
- & Tiebang Kang
Nature Cell Biology 22 , 907–907

Rights & permissionsfor article Author Correction: Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma . Opens in a new window.
Research | 1 June 2020
Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma
- Dan Liao
- , Li Zhong
- , Junqiang Yin
- , Cuiling Zeng
- , Xin Wang
- , Xingchuan Huang
- , Jinna Chen
- , Hong Zhang
- , Ruhua Zhang
- , Xin-Yuan Guan
- , Xintao Shuai
- , Jianhua Sui
- , Song Gao
- , Wuguo Deng
- , Yi-Xin Zeng
- , Jing-Nan Shen
- , Jian Chen
- & Tiebang Kang
Nature Cell Biology 22 , 868–881

Rights & permissionsfor article Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma . Opens in a new window.
Research | 1 August 2017 | Open
FGF2 cooperates with IL-17 to promote autoimmune inflammation
- Xinrui Shao
- , Siyuan Chen
- , Daping Yang
- , Mengtao Cao
- , Yikun Yao
- , Zhengxi Wu
- , Ningli Li
- , Nan Shen
- , Xiaoxia Li
- , Xinyang Song
- & Youcun Qian
Scientific Reports 7 , 1–10

Rights & permissionsfor article FGF2 cooperates with IL-17 to promote autoimmune inflammation . Opens in a new window.
Research | 1 February 2016
Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
- Maria G Dominguez-Bello
- , Kassandra M De Jesus-Laboy
- , Nan Shen
- , Laura M Cox
- , Amnon Amir
- , Antonio Gonzalez
- , Nicholas A Bokulich
- , Se Jin Song
- , Marina Hoashi
- , Juana I Rivera-Vinas
- , Keimari Mendez
- , Rob Knight
- & Jose C Clemente
Nature Medicine 22 , 250–253

Rights & permissionsfor article Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer . Opens in a new window.
Research | 27 October 2016 | Open
CRISPR RNA-guided FokI nucleases repair a PAH variant in a phenylketonuria model
- Yi Pan
- , Nan Shen
- , Sabine Jung-Klawitter
- , Christian Betzen
- , Georg F. Hoffmann
- , Jörg D. Hoheisel
- & Nenad Blau
Scientific Reports 6 , 1–7

Rights & permissionsfor article CRISPR RNA-guided FokI nucleases repair a PAH variant in a phenylketonuria model . Opens in a new window.
Research | 8 August 2016
Low-dose interleukin-2 treatment selectively modulates CD4⁺ T cell subsets in patients with systemic lupus erythematosus
- Jing He
- , Xia Zhang
- , Yunbo Wei
- , Xiaolin Sun
- , Yaping Chen
- , Jun Deng
- , Yuebo Jin
- , Yuzhou Gan
- , Xin Hu
- , Rulin Jia
- , Chuanhui Xu
- , Zhaohua Hou
- , Yew Ann Leong
- , Lei Zhu
- , Jinhong Feng
- , Yuan An
- , Yuan Jia
- , Chun Li
- , Xu Liu
- , Hua Ye
- , Limin Ren
- , Ru Li
- , Haihong Yao
- , Yuhui Li
- , Shi Chen
- , Xuewu Zhang
- , Yin Su
- , Jianping Guo
- , Nan Shen
- , Eric F Morand
- , Di Yu
- & Zhanguo Li
Nature Medicine 22 , 991–993

Rights & permissionsfor article Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus . Opens in a new window.
Research | 1 October 2015 | Open
MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression
- Dan Li
- , Chao Kong
- , Andy Tsun
- , Chen Chen
- , Huihui Song
- , Guochao Shi
- , Wen Pan
- , Dai Dai
- , Nan Shen
- & Bin Li
Scientific Reports 5 , 1–10

Rights & permissionsfor article MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression . Opens in a new window.
Research | 5 November 2012
Angiotensin II regulates the LARG/RhoA/MYPT1 axis in rat vascular smooth muscle in vitro
- Wei-chiao Chiu
- , Jyh-ming Juang
- , Shen-nan Chang
- , Cho-kai Wu
- , Chia-ti Tsai
- , Yung-zu Tseng
- & Fu-tien Chiang
Acta Pharmacologica Sinica 33 , 1502–1510

Rights & permissionsfor article Angiotensin II regulates the LARG/RhoA/MYPT1 axis in rat vascular smooth muscle in vitro . Opens in a new window.
Research | 1 May 2007
Bufalin induces apoptosis in human osteosarcoma U-2OS and U-2OS methotrexate300-resistant cell lines
- Jun-qiang Yin
- , Jing-nan Shen
- , Wei-wei Su
- , Jin Wang
- , Gang Huang
- , Song Jin
- , Qian-chen Guo
- , Chang-ye Zou
- , Hao-miao Li
- & Fo-bao Li
Acta Pharmacologica Sinica 28 , 712–720

Rights & permissionsfor article Bufalin induces apoptosis in human osteosarcoma U-2OS and U-2OS methotrexate300-resistant cell lines . Opens in a new window.
Research | 9 October 2005
A minimal domain responsible for Munc13 activity
- Jayeeta Basu
- , Nan Shen
- , Irina Dulubova
- , Jun Lu
- , Rong Guan
- , Oleg Guryev
- , Nick V Grishin
- , Christian Rosenmund
- & Josep Rizo
Nature Structural & Molecular Biology 12 , 1017–1018

Rights & permissionsfor article A minimal domain responsible for Munc13 activity . Opens in a new window.
Research | 17 May 2019 | Open
Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus
- Simon H. Jiang
- , Vicki Athanasopoulos
- , Julia I. Ellyard
- , Aaron Chuah
- , Jean Cappello
- , Amelia Cook
- , Savit B. Prabhu
- , Jacob Cardenas
- , Jinghua Gu
- , Maurice Stanley
- , Jonathan A. Roco
- , Ilenia Papa
- , Mehmet Yabas
- , Giles D. Walters
- , Gaetan Burgio
- , Kathryn McKeon
- , James M. Byers
- , Charlotte Burrin
- , Anselm Enders
- , Lisa A. Miosge
- , Pablo F. Canete
- , Marija Jelusic
- , Velibor Tasic
- , Adrian C. Lungu
- , Stephen I. Alexander
- , Arthur R. Kitching
- , David A. Fulcher
- , Nan Shen
- , Todor Arsov
- , Paul A. Gatenby
- , Jeff J. Babon
- , Dominic F. Mallon
- , Carmen de Lucas Collantes
- , Eric A. Stone
- , Philip Wu
- , Matthew A. Field
- , Thomas D. Andrews
- , Eun Cho
- , Virginia Pascual
- , Matthew C. Cook
- & Carola G. Vinuesa
Nature Communications 10 , 1–12

Rights & permissionsfor article Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus . Opens in a new window.
Research | 31 May 2019 | Open
Resonance excitation of surface capillary waves to enhance material removal for laser material processing
- Sonny Ly
- , Gabe Guss
- , Alexander M. Rubenchik
- , Wesley J. Keller
- , Nan Shen
- , Raluca A. Negres
- & Jeff Bude
Scientific Reports 9 , 1–9

Rights & permissionsfor article Resonance excitation of surface capillary waves to enhance material removal for laser material processing . Opens in a new window.
Research | 19 March 2018 | Open
Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus
- Junli Liu
- , Xinfang Huang
- , Shumeng Hao
- , Yan Wang
- , Manman Liu
- , Jing Xu
- , Xingli Zhang
- , Tao Yu
- , Shucheng Gan
- , Dongfang Dai
- , Xuan Luo
- , Qingyan Lu
- , Chaoming Mao
- , Yanyun Zhang
- , Nan Shen
- , Bin Li
- , Mingzhu Huang
- , Xiaodong Zhu
- , Jin Jin
- , Xuhong Cheng
- , Shao-Cong Sun
- & Yichuan Xiao
Nature Communications 9 , 1–13

Rights & permissionsfor article Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus . Opens in a new window.
Research | 26 March 2018
MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus
- Linyu Geng
- , Xiaojun Tang
- , Kangxing Zhou
- , Dandan Wang
- , Shiying Wang
- , Genhong Yao
- , Weiwei Chen
- , Xiang Gao
- , Wanjun Chen
- , Songtao Shi
- , Nan Shen
- , Xuebing Feng
- & Lingyun Sun
Cellular & Molecular Immunology 16 , 260–274

Rights & permissionsfor article MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus . Opens in a new window.
Research | 21 March 2018
Type I interferons promote the survival and proinflammatory properties of transitional B cells in systemic lupus erythematosus patients
- Mei Liu
- , Qiang Guo
- , Chunmei Wu
- , Delphine Sterlin
- , Shyamal Goswami
- , Ying Zhang
- , Teng Li
- , Chunde Bao
- , Nan Shen
- , Qiong Fu
- & Xiaoming Zhang
Cellular & Molecular Immunology 16 , 367–379

Rights & permissionsfor article Type I interferons promote the survival and proinflammatory properties of transitional B cells in systemic lupus erythematosus patients . Opens in a new window.
Research | 12 July 2018
Allelic phenotype values: a model for genotype-based phenotype prediction in phenylketonuria
- Sven F. Garbade
- , Nan Shen
- , Nastassja Himmelreich
- , Dorothea Haas
- , Friedrich K. Trefz
- , Georg F. Hoffmann
- , Peter Burgard
- & Nenad Blau
Genetics in Medicine 21 , 580–590

Rights & permissionsfor article Allelic phenotype values: a model for genotype-based phenotype prediction in phenylketonuria . Opens in a new window.
Research | 24 May 2017 | Open
Antigen-specific CD8⁺ T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin
- Yikun Yao
- , Siyuan Chen
- , Mengtao Cao
- , Xing Fan
- , Tao Yang
- , Yin Huang
- , Xinyang Song
- , Yongqin Li
- , Lilin Ye
- , Nan Shen
- , Yufang Shi
- , Xiaoxia Li
- , Feng Wang
- & Youcun Qian
Nature Communications 8 , 1–17

Rights & permissionsfor article Antigen-specific CD8+ T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin . Opens in a new window.
Research | 5 December 2017 | Open
Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation
- Nan Wang
- , Yiyao Deng
- , Anqi Liu
- , Nan Shen
- , Weidong Wang
- , Xiangning Du
- , Qingzhu Tang
- , Shuangxin Li
- , Zach Odeh
- , Taihua Wu
- & Hongli Lin
Scientific Reports 7 , 1–12

Rights & permissionsfor article Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation . Opens in a new window.
Reviews | 5 October 2017
The role of long non-coding RNAs in rheumatic diseases
- Yuanjia Tang
- , Tian Zhou
- , Xiang Yu
- , Zhixin Xue
- & Nan Shen
Nature Reviews Rheumatology 13 , 657–669

Rights & permissionsfor article The role of long non-coding RNAs in rheumatic diseases . Opens in a new window.
Research | 25 January 2016
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
- Celi Sun
- , Julio E Molineros
- , Loren L Looger
- , Xu-jie Zhou
- , Kwangwoo Kim
- , Yukinori Okada
- , Jianyang Ma
- , Yuan-yuan Qi
- , Xana Kim-Howard
- , Prasenjeet Motghare
- , Krishna Bhattarai
- , Adam Adler
- , So-Young Bang
- , Hye-Soon Lee
- , Tae-Hwan Kim
- , Young Mo Kang
- , Chang-Hee Suh
- , Won Tae Chung
- , Yong-Beom Park
- , Jung-Yoon Choe
- , Seung Cheol Shim
- , Yuta Kochi
- , Akari Suzuki
- , Michiaki Kubo
- , Takayuki Sumida
- , Kazuhiko Yamamoto
- , Shin-Seok Lee
- , Young Jin Kim
- , Bok-Ghee Han
- , Mikhail Dozmorov
- , Kenneth M Kaufman
- , Jonathan D Wren
- , John B Harley
- , Nan Shen
- , Kek Heng Chua
- , Hong Zhang
- , Sang-Cheol Bae
- & Swapan K Nath
Nature Genetics 48 , 323–330

Rights & permissionsfor article High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry . Opens in a new window.
Research | 6 January 2017 | Open
Pseudorabies virus infection inhibits autophagy in permissive cells in vitro
- Mingxia Sun
- , Linlin Hou
- , Yan-dong Tang
- , Yonggang Liu
- , Shujie Wang
- , Jingfei Wang
- , Nan Shen
- , Tongqing An
- , Zhijun Tian
- & Xuehui Cai
Scientific Reports 7 , 1–14

Rights & permissionsfor article Pseudorabies virus infection inhibits autophagy in permissive cells in vitro . Opens in a new window.
Research | 16 February 2016 | Open
Phenotypic and functional alterations of pDCs in lupus-prone mice
- Zhenyuan Zhou
- , Jianyang Ma
- , Chunyuan Xiao
- , Xiao Han
- , Rong Qiu
- , Yan Wang
- , Yingying Zhou
- , Li Wu
- , Xinfang Huang
- & Nan Shen
Scientific Reports 6 , 1–11

Rights & permissionsfor article Phenotypic and functional alterations of pDCs in lupus-prone mice . Opens in a new window.
Research | 4 April 2016
Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype
- Leopoldo N. Segal
- , Jose C. Clemente
- , Jun-Chieh J. Tsay
- , Sergei B. Koralov
- , Brian C. Keller
- , Benjamin G. Wu
- , Yonghua Li
- , Nan Shen
- , Elodie Ghedin
- , Alison Morris
- , Phillip Diaz
- , Laurence Huang
- , William R. Wikoff
- , Carles Ubeda
- , Alejandro Artacho
- , William N. Rom
- , Daniel H. Sterman
- , Ronald G. Collman
- , Martin J. Blaser
- & Michael D. Weiden
Nature Microbiology 1 , 1–11

Rights & permissionsfor article Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype . Opens in a new window.
Research | 30 January 2017
A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases
- Betty Tsao, Jian Zhao, Nan Shen and colleagues show that a...
- Jian Zhao
- , Jianyang Ma
- , Yun Deng
- , Jennifer A Kelly
- , Kwangwoo Kim
- , So-Young Bang
- , Hye-Soon Lee
- , Quan-Zhen Li
- , Edward K Wakeland
- , Rong Qiu
- , Mengru Liu
- , Jianping Guo
- , Zhanguo Li
- , Wenfeng Tan
- , Astrid Rasmussen
- , Christopher J Lessard
- , Kathy L Sivils
- , Bevra H Hahn
- , Jennifer M Grossman
- , Diane L Kamen
- , Gary S Gilkeson
- , Sang-Cheol Bae
- , Patrick M Gaffney
- , Nan Shen
- & Betty P Tsao
Nature Genetics 49 , 433–437

Rights & permissionsfor article A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases . Opens in a new window.
Reviews | 7 July 2016
The microbiome in early life: implications for health outcomes
- Sabrina Tamburini
- , Nan Shen
- , Han Chih Wu
- & Jose C Clemente
Nature Medicine 22 , 713–722

Rights & permissionsfor article The microbiome in early life: implications for health outcomes . Opens in a new window.
Research | 31 March 2016 | Open
Autophagy Negatively Regulates Transmissible Gastroenteritis Virus Replication
- Longjun Guo
- , Haidong Yu
- , Weihong Gu
- , Xiaolei Luo
- , Ren Li
- , Jian Zhang
- , Yunfei Xu
- , Lijun Yang
- , Nan Shen
- , Li Feng
- & Yue Wang
Scientific Reports 6 , 1–14

Rights & permissionsfor article Autophagy Negatively Regulates Transmissible Gastroenteritis Virus Replication . Opens in a new window.
Research | 3 July 2015 | Open
NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis
- Sha Yan
- , Zhenyao Xu
- , Fangzhou Lou
- , Lingyun Zhang
- , Fang Ke
- , Jing Bai
- , Zhaoyuan Liu
- , Jinlin Liu
- , Hong Wang
- , Huiyuan Zhu
- , Yang Sun
- , Wei Cai
- , Yuanyuan Gao
- , Bing Su
- , Qun Li
- , Xiao Yang
- , Jianxiu Yu
- , Yuping Lai
- , Xue-Zhong Yu
- , Yan Zheng
- , Nan Shen
- , Y. Eugene Chin
- & Honglin Wang
Nature Communications 6 , 1–15

Rights & permissionsfor article NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis . Opens in a new window.
Research | 15 June 2015 | Open
Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes
- John Beaulaurier
- , Xue-Song Zhang
- , Shijia Zhu
- , Robert Sebra
- , Chaggai Rosenbluh
- , Gintaras Deikus
- , Nan Shen
- , Diana Munera
- , Matthew K. Waldor
- , Andrew Chess
- , Martin J. Blaser
- , Eric E. Schadt
- & Gang Fang
Nature Communications 6 , 1–12

Rights & permissionsfor article Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes . Opens in a new window.
Research | 12 May 2015
MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis
- Wen Pan
- , Shu Zhu
- , Dai Dai
- , Zheng Liu
- , Dan Li
- , Bin Li
- , Nicola Gagliani
- , Yunjiang Zheng
- , Yuanjia Tang
- , Matthew T. Weirauch
- , Xiaoting Chen
- , Wei Zhu
- , Yue Wang
- , Bo Chen
- , Youcun Qian
- , Yingxuan Chen
- , Jingyuan Fang
- , Ronald Herbst
- , Laura Richman
- , Bahija Jallal
- , John B. Harley
- , Richard A. Flavell
- , Yihong Yao
- & Nan Shen
Nature Communications 6 , 1–12

Rights & permissionsfor article MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis . Opens in a new window.
Research | 11 August 2015 | Open
miR-744 enhances type I interferon signaling pathway by targeting PTP1B in primary human renal mesangial cells
- Xiaoyan Zhang
- , Xiao Han
- , Yuanjia Tang
- , Yanfang Wu
- , Bo Qu
- & Nan Shen
Scientific Reports 5 , 1–11

Rights & permissionsfor article miR-744 enhances type I interferon signaling pathway by targeting PTP1B in primary human renal mesangial cells . Opens in a new window.
Research | 1 June 2007
Comparative proteomic analysis of human osteosarcoma and SV40-immortalized normal osteoblastic cell lines
- Qian-chen Guo
- , Jing-nan Shen
- , Song Jin
- , Jin Wang
- , Gang Huang
- , Long-juan Zhang
- , Jun-qiang Yin
- , Chang-ye Zou
- & Ming-tao Li
Acta Pharmacologica Sinica 28 , 850–858

Rights & permissionsfor article Comparative proteomic analysis of human osteosarcoma and SV40-immortalized normal osteoblastic cell lines . Opens in a new window.
Research | 1 March 2008
Establishment and characteristics of two syngeneic human osteosarcoma cell lines from primary tumor and skip metastases
- Chang-ye Zou
- , Jin Wang
- , Jing-nan Shen
- , Gang Huang
- , Song Jin
- , Jun-qiang Yin
- , Qian-chen Guo
- , Hao-miao Li
- , Lan Luo
- , Meng Zhang
- & Long-juan Zhang
Acta Pharmacologica Sinica 29 , 325–332

Rights & permissionsfor article Establishment and characteristics of two syngeneic human osteosarcoma cell lines from primary tumor and skip metastases . Opens in a new window.
Research | 3 June 2012
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α
- Shu Zhu
- , Wen Pan
- , Xinyang Song
- , Yan Liu
- , Xinrui Shao
- , Yuanjia Tang
- , Dong Liang
- , Dongyi He
- , Honglin Wang
- , Wenjun Liu
- , Yufang Shi
- , John B Harley
- , Nan Shen
- & Youcun Qian
Nature Medicine 18 , 1077–1086

Rights & permissionsfor article The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α . Opens in a new window.
Reviews | 16 October 2012
MicroRNAs—novel regulators of systemic lupus erythematosus pathogenesis
- Nan Shen
- , Dong Liang
- , Yuanjia Tang
- , Niek de Vries
- & Paul-Peter Tak
Nature Reviews Rheumatology 8 , 701–709

Rights & permissionsfor article MicroRNAs—novel regulators of systemic lupus erythematosus pathogenesis . Opens in a new window.

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SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression

Author Correction: Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma

Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma

FGF2 cooperates with IL-17 to promote autoimmune inflammation

Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer

CRISPR RNA-guided FokI nucleases repair a PAH variant in a phenylketonuria model

Low-dose interleukin-2 treatment selectively modulates CD4⁺ T cell subsets in patients with systemic lupus erythematosus

MiR-125a-5p Decreases the Sensitivity of Treg cells Toward IL-6-Mediated Conversion by Inhibiting IL-6R and STAT3 Expression

Angiotensin II regulates the LARG/RhoA/MYPT1 axis in rat vascular smooth muscle in vitro

Bufalin induces apoptosis in human osteosarcoma U-2OS and U-2OS methotrexate300-resistant cell lines

A minimal domain responsible for Munc13 activity

Functional rare and low frequency variants in BLK and BANK1 contribute to human lupus

Resonance excitation of surface capillary waves to enhance material removal for laser material processing

Peli1 negatively regulates noncanonical NF-κB signaling to restrain systemic lupus erythematosus

MicroRNA-663 induces immune dysregulation by inhibiting TGF-β1 production in bone marrow-derived mesenchymal stem cells in patients with systemic lupus erythematosus

Type I interferons promote the survival and proinflammatory properties of transitional B cells in systemic lupus erythematosus patients

Allelic phenotype values: a model for genotype-based phenotype prediction in phenylketonuria

Antigen-specific CD8⁺ T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin

Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation

The role of long non-coding RNAs in rheumatic diseases

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

Pseudorabies virus infection inhibits autophagy in permissive cells in vitro

Phenotypic and functional alterations of pDCs in lupus-prone mice

Enrichment of the lung microbiome with oral taxa is associated with lung inflammation of a Th17 phenotype

A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases

The microbiome in early life: implications for health outcomes

Autophagy Negatively Regulates Transmissible Gastroenteritis Virus Replication

NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis

Single molecule-level detection and long read-based phasing of epigenetic variations in bacterial methylomes

MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis

miR-744 enhances type I interferon signaling pathway by targeting PTP1B in primary human renal mesangial cells

Comparative proteomic analysis of human osteosarcoma and SV40-immortalized normal osteoblastic cell lines

Establishment and characteristics of two syngeneic human osteosarcoma cell lines from primary tumor and skip metastases

The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

MicroRNAs—novel regulators of systemic lupus erythematosus pathogenesis

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