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Research | 4 May 2020 | Open
Region-specific effects of Scrapper on the abundance of glutamate and gamma-aminobutyric acid in the mouse brain
- Fumihiro Eto
- , Shumpei Sato
- , Mitsutoshi Setou
- & Ikuko Yao
Scientific Reports 10 , 1–10

Rights & permissionsfor article Region-specific effects of Scrapper on the abundance of glutamate and gamma-aminobutyric acid in the mouse brain . Opens in a new window.
Research | 13 September 2019 | Open
Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter
Scientific Reports 9 , 1–11

Rights & permissionsfor article Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter . Opens in a new window.
Research | 9 July 2018 | Open
A power law distribution of metabolite abundance levels in mice regardless of the time and spatial scale of analysis
Scientific Reports 8 , 1–8

Rights & permissionsfor article A power law distribution of metabolite abundance levels in mice regardless of the time and spatial scale of analysis . Opens in a new window.
Research | 13 February 2018 | Open
Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice
- Hidehiko Suzuki
- , Takahiro Nagatake
- , Ayaka Nasu
- , Huangwenxian Lan
- , Koji Ikegami
- , Mitsutoshi Setou
- , Yoko Hamazaki
- , Hiroshi Kiyono
- , Kiyohito Yagi
- , Masuo Kondoh
- & Jun Kunisawa
Scientific Reports 8 , 1–9

Rights & permissionsfor article Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice . Opens in a new window.
Research | 29 April 2020 | Open
Brain distribution of geissoschizine methyl ether in rats using mass spectrometry imaging analysis
Scientific Reports 10 , 1–11

Rights & permissionsfor article Brain distribution of geissoschizine methyl ether in rats using mass spectrometry imaging analysis . Opens in a new window.
Research | 8 March 2017 | Open
Distribution Analysis via Mass Spectrometry Imaging of Ephedrine in the Lungs of Rats Orally Administered the Japanese Kampo Medicine Maoto
- Takashi Matsumoto
- , Hirotaka Kushida
- , Shoko Matsushita
- , Yoshiyuki Oyama
- , Takafumi Suda
- , Junko Watanabe
- , Yoshio Kase
- & Mitsutoshi Setou
Scientific Reports 7 , 1–8

Rights & permissionsfor article Distribution Analysis via Mass Spectrometry Imaging of Ephedrine in the Lungs of Rats Orally Administered the Japanese Kampo Medicine Maoto . Opens in a new window.
Research | 23 May 2016 | Open
Increased arachidonic acid-containing phosphatidylcholine is associated with reactive microglia and astrocytes in the spinal cord after peripheral nerve injury
- Dongmin Xu
- , Takao Omura
- , Noritaka Masaki
- , Hideyuki Arima
- , Tomohiro Banno
- , Ayako Okamoto
- , Mitsuru Hanada
- , Shiro Takei
- , Shoko Matsushita
- , Eiji Sugiyama
- , Mitsutoshi Setou
- & Yukihiro Matsuyama
Scientific Reports 6 , 1–11

Rights & permissionsfor article Increased arachidonic acid-containing phosphatidylcholine is associated with reactive microglia and astrocytes in the spinal cord after peripheral nerve injury . Opens in a new window.
Research | 8 August 2016 | Open
Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm
- Hirona Kugo
- , Nobuhiro Zaima
- , Hiroki Tanaka
- , Youhei Mouri
- , Kenichi Yanagimoto
- , Kohsuke Hayamizu
- , Keisuke Hashimoto
- , Takeshi Sasaki
- , Masaki Sano
- , Tatsuro Yata
- , Tetsumei Urano
- , Mitsutoshi Setou
- , Naoki Unno
- & Tatsuya Moriyama
Scientific Reports 6 , 1–12

Rights & permissionsfor article Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm . Opens in a new window.
Research | 20 November 2013 | Open
Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat diet
- Naoko Goto-Inoue
- , Kenichiro Yamada
- , Akiko Inagaki
- , Yasuro Furuichi
- , Shinya Ogino
- , Yasuko Manabe
- , Mitsutoshi Setou
- & Nobuharu L. Fujii
Scientific Reports 3 , 1–9

Rights & permissionsfor article Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat diet . Opens in a new window.
Research | 11 June 2015 | Open
Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut
- Jun Kunisawa
- , Makoto Arita
- , Takahiro Hayasaka
- , Takashi Harada
- , Ryo Iwamoto
- , Risa Nagasawa
- , Shiori Shikata
- , Takahiro Nagatake
- , Hidehiko Suzuki
- , Eri Hashimoto
- , Yosuke Kurashima
- , Yuji Suzuki
- , Hiroyuki Arai
- , Mitsutoshi Setou
- & Hiroshi Kiyono
Scientific Reports 5 , 1–8

Rights & permissionsfor article Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut . Opens in a new window.
Research | 14 April 2002
Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites
Nature 417 , 83–87

Rights & permissionsfor article Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites . Opens in a new window.
Research | 26 September 2018 | Open
UBL3 modification influences protein sorting to small extracellular vesicles
- Hiroshi Ageta
- , Natsumi Ageta-Ishihara
- , Keisuke Hitachi
- , Ozge Karayel
- , Takanori Onouchi
- , Hisateru Yamaguchi
- , Tomoaki Kahyo
- , Ken Hatanaka
- , Koji Ikegami
- , Yusuke Yoshioka
- , Kenji Nakamura
- , Nobuyoshi Kosaka
- , Masashi Nakatani
- , Akiyoshi Uezumi
- , Tomihiko Ide
- , Yutaka Tsutsumi
- , Haruhiko Sugimura
- , Makoto Kinoshita
- , Takahiro Ochiya
- , Matthias Mann
- , Mitsutoshi Setou
- & Kunihiro Tsuchida
Nature Communications 9 , 1–12

Rights & permissionsfor article UBL3 modification influences protein sorting to small extracellular vesicles . Opens in a new window.
Research | 22 October 2018 | Open
Three-dimensional tracking of microbeads attached to the tip of single isolated tracheal cilia beating under external load
- Takanobu A. Katoh
- , Koji Ikegami
- , Nariya Uchida
- , Toshihito Iwase
- , Daisuke Nakane
- , Tomoko Masaike
- , Mitsutoshi Setou
- & Takayuki Nishizaka
Scientific Reports 8 , 1–9

Rights & permissionsfor article Three-dimensional tracking of microbeads attached to the tip of single isolated tracheal cilia beating under external load . Opens in a new window.
Research | 30 May 2018 | Open
Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway
- Yoshishige Kimura
- , Koji Tsutsumi
- , Alu Konno
- , Koji Ikegami
- , Saira Hameed
- , Tomomi Kaneko
- , Oktay Ismail Kaplan
- , Takayuki Teramoto
- , Manabi Fujiwara
- , Takeshi Ishihara
- , Oliver E. Blacque
- & Mitsutoshi Setou
Scientific Reports 8 , 1–13

Rights & permissionsfor article Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway . Opens in a new window.
Research | 20 July 2016 | Open
Accumulation of arachidonic acid-containing phosphatidylinositol at the outer edge of colorectal cancer
- Takanori Hiraide
- , Koji Ikegami
- , Takanori Sakaguchi
- , Yoshifumi Morita
- , Takahiro Hayasaka
- , Noritaka Masaki
- , Michihiko Waki
- , Eiji Sugiyama
- , Satoru Shinriki
- , Makoto Takeda
- , Yasushi Shibasaki
- , Shinichiro Miyazaki
- , Hirotoshi Kikuchi
- , Hiroaki Okuyama
- , Masahiro Inoue
- , Mitsutoshi Setou
- & Hiroyuki Konno
Scientific Reports 6 , 1–11

Rights & permissionsfor article Accumulation of arachidonic acid-containing phosphatidylinositol at the outer edge of colorectal cancer . Opens in a new window.
Research | 9 January 2017 | Open
Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer’s disease
Scientific Reports 7 , 1–14

Rights & permissionsfor article Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer’s disease . Opens in a new window.
Research | 23 March 2017 | Open
Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia
- Junya Matsumoto
- , Hiroki Nakanishi
- , Yasuto Kunii
- , Yuki Sugiura
- , Dai Yuki
- , Akira Wada
- , Mizuki Hino
- , Shin-Ichi Niwa
- , Takeshi Kondo
- , Michihiko Waki
- , Takahiro Hayasaka
- , Noritaka Masaki
- , Hiroyasu Akatsu
- , Yoshio Hashizume
- , Sakon Yamamoto
- , Shinji Sato
- , Takehiko Sasaki
- , Mitsutoshi Setou
- & Hirooki Yabe
Scientific Reports 7 , 1–11

Rights & permissionsfor article Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia . Opens in a new window.
Research | 11 May 2015 | Open
Three-Dimensional Image of Cleavage Bodies in Nuclei Is Configured Using Gas Cluster Ion Beam with Time-of-Flight Secondary Ion Mass Spectrometry
Scientific Reports 5 , 1–10

Rights & permissionsfor article Three-Dimensional Image of Cleavage Bodies in Nuclei Is Configured Using Gas Cluster Ion Beam with Time-of-Flight Secondary Ion Mass Spectrometry . Opens in a new window.
Research | 20 November 2014 | Open
DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease
- Dai Yuki
- , Yuki Sugiura
- , Nobuhiro Zaima
- , Hiroyasu Akatsu
- , Shiro Takei
- , Ikuko Yao
- , Masato Maesako
- , Ayae Kinoshita
- , Takayuki Yamamoto
- , Ryo Kon
- , Keikichi Sugiyama
- & Mitsutoshi Setou
Scientific Reports 4 , 1–9

Rights & permissionsfor article DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease . Opens in a new window.
Research | 19 April 2009
Tubulin tyrosination navigates the kinesin-1 motor domain to axons
- Yoshiyuki Konishi
- & Mitsutoshi Setou
Nature Neuroscience 12 , 559–567

Rights & permissionsfor article Tubulin tyrosination navigates the kinesin-1 motor domain to axons . Opens in a new window.
Research | 15 January 2012
CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium
- Ji Eun Lee
- , Jennifer L Silhavy
- , Maha S Zaki
- , Jana Schroth
- , Stephanie L Bielas
- , Sarah E Marsh
- , Jesus Olvera
- , Francesco Brancati
- , Miriam Iannicelli
- , Koji Ikegami
- , Andrew M Schlossman
- , Barry Merriman
- , Tania Attié-Bitach
- , Clare V Logan
- , Ian A Glass
- , Andrew Cluckey
- , Carrie M Louie
- , Jeong Ho Lee
- , Hilary R Raynes
- , Isabelle Rapin
- , Ignacio P Castroviejo
- , Mitsutoshi Setou
- , Clara Barbot
- , Eugen Boltshauser
- , Stanley F Nelson
- , Friedhelm Hildebrandt
- , Colin A Johnson
- , Daniel A Doherty
- , Enza Maria Valente
- & Joseph G Gleeson
Nature Genetics 44 , 193–199

Rights & permissionsfor article <i>CEP41</i> is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium . Opens in a new window.

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Region-specific effects of Scrapper on the abundance of glutamate and gamma-aminobutyric acid in the mouse brain

Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter

A power law distribution of metabolite abundance levels in mice regardless of the time and spatial scale of analysis

Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice

Brain distribution of geissoschizine methyl ether in rats using mass spectrometry imaging analysis

Distribution Analysis via Mass Spectrometry Imaging of Ephedrine in the Lungs of Rats Orally Administered the Japanese Kampo Medicine Maoto

Increased arachidonic acid-containing phosphatidylcholine is associated with reactive microglia and astrocytes in the spinal cord after peripheral nerve injury

Adipocyte in vascular wall can induce the rupture of abdominal aortic aneurysm

Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat diet

Dietary ω3 fatty acid exerts anti-allergic effect through the conversion to 17,18-epoxyeicosatetraenoic acid in the gut

Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites

UBL3 modification influences protein sorting to small extracellular vesicles

Three-dimensional tracking of microbeads attached to the tip of single isolated tracheal cilia beating under external load

Environmental responsiveness of tubulin glutamylation in sensory cilia is regulated by the p38 MAPK pathway

Accumulation of arachidonic acid-containing phosphatidylinositol at the outer edge of colorectal cancer

Increase in α-tubulin modifications in the neuronal processes of hippocampal neurons in both kainic acid-induced epileptic seizure and Alzheimer’s disease

Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia

Three-Dimensional Image of Cleavage Bodies in Nuclei Is Configured Using Gas Cluster Ion Beam with Time-of-Flight Secondary Ion Mass Spectrometry

DHA-PC and PSD-95 decrease after loss of synaptophysin and before neuronal loss in patients with Alzheimer's disease

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium

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