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Amendments and Corrections | 24 July 2020 | Open
Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery
- Andrew R. Burns
- , Genna M. Luciani
- , Gabriel Musso
- , Rachel Bagg
- , May Yeo
- , Yuqian Zhang
- , Luckshi Rajendran
- , John Glavin
- , Robert Hunter
- , Elizabeth Redman
- , Susan Stasiuk
- , Michael Schertzberg
- , G. Angus McQuibban
- , Conor R. Caffrey
- , Sean R. Cutler
- , Mike Tyers
- , Guri Giaever
- , Corey Nislow
- , Andy G. Fraser
- , Calum A. MacRae
- , John Gilleard
- & Peter J. Roy
Nature Communications 11 , 1–1

Rights & permissionsfor article Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery . Opens in a new window.
Amendments and Corrections | 26 May 2020 | Open
Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
- Magdalena M. Szewczyk
- , Yoshinori Ishikawa
- , Shawna Organ
- , Nozomu Sakai
- , Fengling Li
- , Levon Halabelian
- , Suzanne Ackloo
- , Amber L. Couzens
- , Mohammad Eram
- , David Dilworth
- , Hideto Fukushi
- , Rachel Harding
- , Carlo C. dela Seña
- , Tsukasa Sugo
- , Kozo Hayashi
- , David McLeod
- , Carlos Zepeda
- , Ahmed Aman
- , Maria Sánchez-Osuna
- , Eric Bonneil
- , Shinji Takagi
- , Rima Al-Awar
- , Mike Tyers
- , Stephane Richard
- , Masayuki Takizawa
- , Anne-Claude Gingras
- , Cheryl H. Arrowsmith
- , Masoud Vedadi
- , Peter J. Brown
- , Hiroshi Nara
- & Dalia Barsyte-Lovejoy
Nature Communications 11 , 1–1

Rights & permissionsfor article Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response . Opens in a new window.
Correspondence | 19 June 2019
Gene Information eXtension (GIX): effortless retrieval of gene product information on any website
Nature Methods 16 , 665–666

Rights & permissionsfor article Gene Information eXtension (GIX): effortless retrieval of gene product information on any website . Opens in a new window.
Research | 14 May 2020 | Open
Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response
- Magdalena M. Szewczyk
- , Yoshinori Ishikawa
- , Shawna Organ
- , Nozomu Sakai
- , Fengling Li
- , Levon Halabelian
- , Suzanne Ackloo
- , Amber L. Couzens
- , Mohammad Eram
- , David Dilworth
- , Hideto Fukushi
- , Rachel Harding
- , Carlo C. dela Seña
- , Tsukasa Sugo
- , Kozo Hayashi
- , David McLeod
- , Carlos Zepeda
- , Ahmed Aman
- , Maria Sánchez-Osuna
- , Eric Bonneil
- , Shinji Takagi
- , Rima Al-Awar
- , Mike Tyers
- , Stephane Richard
- , Masayuki Takizawa
- , Anne-Claude Gingras
- , Cheryl H. Arrowsmith
- , Masoud Vedadi
- , Peter J. Brown
- , Hiroshi Nara
- & Dalia Barsyte-Lovejoy
Nature Communications 11 , 1–15

Rights & permissionsfor article Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response . Opens in a new window.
Correspondence | 30 January 2014
BoxPlotR: a web tool for generation of box plots
Nature Methods 11 , 121–122

Rights & permissionsfor article BoxPlotR: a web tool for generation of box plots . Opens in a new window.
Research | 15 February 2001
The cell-cycle regulatory protein Cks1 is required for SCF^Skp2-mediated ubiquitinylation of p27
- Dvora Ganoth
- , Gil Bornstein
- , Tun K. Ko
- , Brett Larsen
- , Mike Tyers
- , Michele Pagano
- & Avram Hershko
Nature Cell Biology 3 , 321–324

Rights & permissionsfor article The cell-cycle regulatory protein Cks1 is required for SCFSkp2-mediated ubiquitinylation of p27 . Opens in a new window.
Research | 3 September 2003
The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase
- Lionel Pintard
- , John H. Willis
- , Andrew Willems
- , Jacque-Lynne F. Johnson
- , Martin Srayko
- , Thimo Kurz
- , Sarah Glaser
- , Paul E. Mains
- , Mike Tyers
- , Bruce Bowerman
- & Matthias Peter
Nature 425 , 311–316

Rights & permissionsfor article The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase . Opens in a new window.
News and Views | 20 September 2001
Archipelago of destruction
- Michael Schwab
- & Mike Tyers
Nature 413 , 268–269

Rights & permissionsfor article Archipelago of destruction . Opens in a new window.
Reviews | 27 March 2012
Protein interaction data curation: the International Molecular Exchange (IMEx) consortium
- Sandra Orchard
- , Samuel Kerrien
- , Sara Abbani
- , Bruno Aranda
- , Jignesh Bhate
- , Shelby Bidwell
- , Alan Bridge
- , Leonardo Briganti
- , Fiona S L Brinkman
- , Gianni Cesareni
- , Andrew Chatr-aryamontri
- , Emilie Chautard
- , Carol Chen
- , Marine Dumousseau
- , Johannes Goll
- , Robert E W Hancock
- , Linda I Hannick
- , Igor Jurisica
- , Jyoti Khadake
- , David J Lynn
- , Usha Mahadevan
- , Livia Perfetto
- , Arathi Raghunath
- , Sylvie Ricard-Blum
- , Bernd Roechert
- , Lukasz Salwinski
- , Volker Stümpflen
- , Mike Tyers
- , Peter Uetz
- , Ioannis Xenarios
- & Henning Hermjakob
Nature Methods 9 , 345–350

Rights & permissionsfor article Protein interaction data curation: the International Molecular Exchange (IMEx) consortium . Opens in a new window.
Special Features | 13 March 2003
From genomics to proteomics
- Mike Tyers
- & Matthias Mann
Nature 422 , 193–197

Rights & permissionsfor article From genomics to proteomics . Opens in a new window.
Research | 22 September 1994
Inhibition of Gl cyclin activity by the Ras/cAMP pathway in yeast
- George Tokiwa
- , Mike Tyers
- , Tom Volpe
- & Bruce Futcher
Nature 371 , 342–345

Rights & permissionsfor article Inhibition of Gl cyclin activity by the Ras/cAMP pathway in yeast . Opens in a new window.
Amendments and Corrections | 30 May 2012
Correction: Corrigendum: Protein interaction data curation: the International Molecular Exchange (IMEx) consortium
- Sandra Orchard
- , Samuel Kerrien
- , Sara Abbani
- , Bruno Aranda
- , Jignesh Bhate
- , Shelby Bidwell
- , Alan Bridge
- , Leonardo Briganti
- , Fiona Brinkman
- , Gianni Cesareni
- , Andrew Chatr-aryamontri
- , Emilie Chautard
- , Carol Chen
- , Marine Dumousseau
- , Johannes Goll
- , Robert Hancock
- , Linda I Hannick
- , Igor Jurisica
- , Jyoti Khadake
- , David J Lynn
- , Usha Mahadevan
- , Livia Perfetto
- , Arathi Raghunath
- , Sylvie Ricard-Blum
- , Bernd Roechert
- , Lukasz Salwinski
- , Volker Stümpflen
- , Mike Tyers
- , Peter Uetz
- , Ioannis Xenarios
- & Henning Hermjakob
Nature Methods 9 , 626–626

Rights & permissionsfor article Correction: Corrigendum: Protein interaction data curation: the International Molecular Exchange (IMEx) consortium . Opens in a new window.
Research | 27 June 2010
An allosteric inhibitor of substrate recognition by the SCF^Cdc4 ubiquitin ligase
- Stephen Orlicky
- , Xiaojing Tang
- , Victor Neduva
- , Nadine Elowe
- , Eric D Brown
- , Frank Sicheri
- & Mike Tyers
Nature Biotechnology 28 , 733–737

Rights & permissionsfor article An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase . Opens in a new window.
Research | 24 April 2011
Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy
- Linda Ejim
- , Maya A Farha
- , Shannon B Falconer
- , Jan Wildenhain
- , Brian K Coombes
- , Mike Tyers
- , Eric D Brown
- & Gerard D Wright
Nature Chemical Biology 7 , 348–350

Rights & permissionsfor article Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy . Opens in a new window.
Correspondence | 29 June 2011
PSICQUIC and PSISCORE: accessing and scoring molecular interactions
- Bruno Aranda
- , Hagen Blankenburg
- , Samuel Kerrien
- , Fiona S L Brinkman
- , Arnaud Ceol
- , Emilie Chautard
- , Jose M Dana
- , Javier De Las Rivas
- , Marine Dumousseau
- , Eugenia Galeota
- , Anna Gaulton
- , Johannes Goll
- , Robert E W Hancock
- , Ruth Isserlin
- , Rafael C Jimenez
- , Jules Kerssemakers
- , Jyoti Khadake
- , David J Lynn
- , Magali Michaut
- , Gavin O'Kelly
- , Keiichiro Ono
- , Sandra Orchard
- , Carlos Prieto
- , Sabry Razick
- , Olga Rigina
- , Lukasz Salwinski
- , Milan Simonovic
- , Sameer Velankar
- , Andrew Winter
- , Guanming Wu
- , Gary D Bader
- , Gianni Cesareni
- , Ian M Donaldson
- , David Eisenberg
- , Gerard J Kleywegt
- , John Overington
- , Sylvie Ricard-Blum
- , Mike Tyers
- , Mario Albrecht
- & Henning Hermjakob
Nature Methods 8 , 528–529

Rights & permissionsfor article PSICQUIC and PSISCORE: accessing and scoring molecular interactions . Opens in a new window.
2 February 2011 | Open
The BioGRID Interaction Database
- Julie Nixon
- , Mike Tyers
- , Teresa Reguly
- , Jennifer Rust
- , Andrew Winter
- , Michael Livstone
- , Bobby-Joe Breitkreutz
- , Chris Stark
- , Lorrie Boucher
- , Andrew Chatr-Aryamontri
- , Kara Dolinski
- & Rose Oughtred
Nature Precedings , 1–1

Rights & permissionsfor article The BioGRID Interaction Database . Opens in a new window.
Research | 3 September 1998
Yeast G1 cyclins are unstable in G1 phase
Nature 395 , 86–89

Rights & permissionsfor article Yeast G1 cyclins are unstable in G1 phase . Opens in a new window.
Research | 5 December 2010
SAINT: probabilistic scoring of affinity purification–mass spectrometry data
Nature Methods 8 , 70–73

Rights & permissionsfor article SAINT: probabilistic scoring of affinity purification–mass spectrometry data . Opens in a new window.
Correspondence | 13 October 2010
ProHits: integrated software for mass spectrometry–based interaction proteomics
- Guomin Liu
- , Jianping Zhang
- , Brett Larsen
- , Chris Stark
- , Ashton Breitkreutz
- , Zhen-Yuan Lin
- , Bobby-Joe Breitkreutz
- , Yongmei Ding
- , Karen Colwill
- , Adrian Pasculescu
- , Tony Pawson
- , Jeffrey L Wrana
- , Alexey I Nesvizhskii
- , Brian Raught
- , Mike Tyers
- & Anne-Claude Gingras
Nature Biotechnology 28 , 1015–1017

Rights & permissionsfor article ProHits: integrated software for mass spectrometry–based interaction proteomics . Opens in a new window.
Reviews | 8 August 2007
The minimum information required for reporting a molecular interaction experiment (MIMIx)
- Sandra Orchard
- , Lukasz Salwinski
- , Samuel Kerrien
- , Luisa Montecchi-Palazzi
- , Matthias Oesterheld
- , Volker Stümpflen
- , Arnaud Ceol
- , Andrew Chatr-aryamontri
- , John Armstrong
- , Peter Woollard
- , John J Salama
- , Susan Moore
- , Jérôme Wojcik
- , Gary D Bader
- , Marc Vidal
- , Michael E Cusick
- , Mark Gerstein
- , Anne-Claude Gavin
- , Giulio Superti-Furga
- , Jack Greenblatt
- , Joel Bader
- , Peter Uetz
- , Mike Tyers
- , Pierre Legrain
- , Stan Fields
- , Nicola Mulder
- , Michael Gilson
- , Michael Niepmann
- , Lyle Burgoon
- , Javier De Las Rivas
- , Carlos Prieto
- , Victoria M Perreau
- , Chris Hogue
- , Hans-Werner Mewes
- , Rolf Apweiler
- , Ioannis Xenarios
- , David Eisenberg
- , Gianni Cesareni
- & Henning Hermjakob
Nature Biotechnology 25 , 894–898

Rights & permissionsfor article The minimum information required for reporting a molecular interaction experiment (MIMIx) . Opens in a new window.
Research | 10 January 2002
Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry
- Yuen Ho
- , Albrecht Gruhler
- , Adrian Heilbut
- , Gary D. Bader
- , Lynda Moore
- , Sally-Lin Adams
- , Anna Millar
- , Paul Taylor
- , Keiryn Bennett
- , Kelly Boutilier
- , Lingyun Yang
- , Cheryl Wolting
- , Ian Donaldson
- , Søren Schandorff
- , Juanita Shewnarane
- , Mai Vo
- , Joanne Taggart
- , Marilyn Goudreault
- , Brenda Muskat
- , Cris Alfarano
- , Danielle Dewar
- , Zhen Lin
- , Katerina Michalickova
- , Andrew R. Willems
- , Holly Sassi
- , Peter A. Nielsen
- , Karina J. Rasmussen
- , Jens R. Andersen
- , Lene E. Johansen
- , Lykke H. Hansen
- , Hans Jespersen
- , Alexandre Podtelejnikov
- , Eva Nielsen
- , Janne Crawford
- , Vibeke Poulsen
- , Birgitte D. Sørensen
- , Jesper Matthiesen
- , Ronald C. Hendrickson
- , Frank Gleeson
- , Tony Pawson
- , Michael F. Moran
- , Daniel Durocher
- , Matthias Mann
- , Christopher W. V. Hogue
- , Daniel Figeys
- & Mike Tyers
Nature 415 , 180–183

Rights & permissionsfor article Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry . Opens in a new window.
Correspondence | 1 December 2009
Recurated protein interaction datasets
- Lukasz Salwinski
- , Luana Licata
- , Andrew Winter
- , David Thorneycroft
- , Jyoti Khadake
- , Arnaud Ceol
- , Andrew Chatr Aryamontri
- , Rose Oughtred
- , Michael Livstone
- , Lorrie Boucher
- , David Botstein
- , Kara Dolinski
- , Tanya Berardini
- , Eva Huala
- , Mike Tyers
- , David Eisenberg
- , Gianni Cesareni
- & Henning Hermjakob
Nature Methods 6 , 860–861

Rights & permissionsfor article Recurated protein interaction datasets . Opens in a new window.
Research | 1 December 2005
Global analysis of protein phosphorylation in yeast
- Jason Ptacek
- , Geeta Devgan
- , Gregory Michaud
- , Heng Zhu
- , Xiaowei Zhu
- , Joseph Fasolo
- , Hong Guo
- , Ghil Jona
- , Ashton Breitkreutz
- , Richelle Sopko
- , Rhonda R. McCartney
- , Martin C. Schmidt
- , Najma Rachidi
- , Soo-Jung Lee
- , Angie S. Mah
- , Lihao Meng
- , Michael J. R. Stark
- , David F. Stern
- , Claudio De Virgilio
- , Mike Tyers
- , Brenda Andrews
- , Mark Gerstein
- , Barry Schweitzer
- , Paul F. Predki
- & Michael Snyder
Nature 438 , 679–684

Rights & permissionsfor article Global analysis of protein phosphorylation in yeast . Opens in a new window.
Reviews | 25 January 2019
Drug combinations: a strategy to extend the life of antibiotics in the 21st century
- Mike Tyers
- & Gerard D. Wright
Nature Reviews Microbiology 17 , 141–155

Rights & permissionsfor article Drug combinations: a strategy to extend the life of antibiotics in the 21st century . Opens in a new window.
Reviews | 13 October 2017
WD40 repeat domain proteins: a novel target class?
Nature Reviews Drug Discovery 16 , 773–786

Rights & permissionsfor article WD40 repeat domain proteins: a novel target class? . Opens in a new window.
Research | 3 January 2017 | Open
An allosteric conduit facilitates dynamic multisite substrate recognition by the SCF^Cdc4 ubiquitin ligase
- Veronika Csizmok
- , Stephen Orlicky
- , Jing Cheng
- , Jianhui Song
- , Alaji Bah
- , Neda Delgoshaie
- , Hong Lin
- , Tanja Mittag
- , Frank Sicheri
- , Hue Sun Chan
- , Mike Tyers
- & Julie D. Forman-Kay
Nature Communications 8 , 1–14

Rights & permissionsfor article An allosteric conduit facilitates dynamic multisite substrate recognition by the SCFCdc4 ubiquitin ligase . Opens in a new window.
Research | 22 November 2016 | Open
Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism
- Jan Wildenhain
- , Michaela Spitzer
- , Sonam Dolma
- , Nick Jarvik
- , Rachel White
- , Marcia Roy
- , Emma Griffiths
- , David S. Bellows
- , Gerard D. Wright
- & Mike Tyers
Scientific Data 3 , 1–9

Rights & permissionsfor article Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism . Opens in a new window.
Research | 25 June 2015 | Open
Caenorhabditis elegans is a useful model for anthelmintic discovery
- Andrew R. Burns
- , Genna M. Luciani
- , Gabriel Musso
- , Rachel Bagg
- , May Yeo
- , Yuqian Zhang
- , Luckshika Rajendran
- , John Glavin
- , Robert Hunter
- , Elizabeth Redman
- , Susan Stasiuk
- , Michael Schertzberg
- , G. Angus McQuibban
- , Conor R. Caffrey
- , Sean R. Cutler
- , Mike Tyers
- , Guri Giaever
- , Corey Nislow
- , Andy G. Fraser
- , Calum A. MacRae
- , John Gilleard
- & Peter J. Roy
Nature Communications 6 , 1–11

Rights & permissionsfor article Caenorhabditis elegans is a useful model for anthelmintic discovery . Opens in a new window.
Research | 15 December 2013
E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin
- Hao Huang
- , Derek F Ceccarelli
- , Stephen Orlicky
- , Daniel J St-Cyr
- , Amy Ziemba
- , Pankaj Garg
- , Serge Plamondon
- , Manfred Auer
- , Sachdev Sidhu
- , Anne Marinier
- , Gary Kleiger
- , Mike Tyers
- & Frank Sicheri
Nature Chemical Biology 10 , 156–163

Rights & permissionsfor article E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin . Opens in a new window.
Research | 30 May 2010
A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans
- Andrew R Burns
- , Iain M Wallace
- , Jan Wildenhain
- , Mike Tyers
- , Guri Giaever
- , Gary D Bader
- , Corey Nislow
- , Sean R Cutler
- & Peter J Roy
Nature Chemical Biology 6 , 549–557

Rights & permissionsfor article A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans . Opens in a new window.
Research | 8 April 2007
Chemical genetics reveals a complex functional ground state of neural stem cells
- Phedias Diamandis
- , Jan Wildenhain
- , Ian D Clarke
- , Adrian G Sacher
- , Jeremy Graham
- , David S Bellows
- , Erick K M Ling
- , Ryan J Ward
- , Leanne G Jamieson
- , Mike Tyers
- & Peter B Dirks
Nature Chemical Biology 3 , 268–273

Rights & permissionsfor article Chemical genetics reveals a complex functional ground state of neural stem cells . Opens in a new window.
Research | 29 November 2001
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
- Piers Nash
- , Xiaojing Tang
- , Stephen Orlicky
- , Qinghua Chen
- , Frank B. Gertler
- , Michael D. Mendenhall
- , Frank Sicheri
- , Tony Pawson
- & Mike Tyers
Nature 414 , 514–521

Rights & permissionsfor article Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication . Opens in a new window.
Research | 9 November 2008
Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases
- Alexander U Singer
- , John R Rohde
- , Robert Lam
- , Tatiana Skarina
- , Olga Kagan
- , Rosa DiLeo
- , Nickolay Y Chirgadze
- , Marianne E Cuff
- , Andrzej Joachimiak
- , Mike Tyers
- , Philippe J Sansonetti
- , Claude Parsot
- & Alexei Savchenko
Nature Structural & Molecular Biology 15 , 1293–1301

Rights & permissionsfor article Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases . Opens in a new window.

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Author Correction: Caenorhabditis elegans is a useful model for anthelmintic discovery

Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

Gene Information eXtension (GIX): effortless retrieval of gene product information on any website

Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

BoxPlotR: a web tool for generation of box plots

The cell-cycle regulatory protein Cks1 is required for SCF^Skp2-mediated ubiquitinylation of p27

The BTB protein MEL-26 is a substrate-specific adaptor of the CUL-3 ubiquitin-ligase

Archipelago of destruction

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium

From genomics to proteomics

Inhibition of Gl cyclin activity by the Ras/cAMP pathway in yeast

Correction: Corrigendum: Protein interaction data curation: the International Molecular Exchange (IMEx) consortium

An allosteric inhibitor of substrate recognition by the SCF^Cdc4 ubiquitin ligase

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy

PSICQUIC and PSISCORE: accessing and scoring molecular interactions

The BioGRID Interaction Database

Yeast G1 cyclins are unstable in G1 phase

SAINT: probabilistic scoring of affinity purification–mass spectrometry data

ProHits: integrated software for mass spectrometry–based interaction proteomics

The minimum information required for reporting a molecular interaction experiment (MIMIx)

Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry

Recurated protein interaction datasets

Global analysis of protein phosphorylation in yeast

Drug combinations: a strategy to extend the life of antibiotics in the 21st century

WD40 repeat domain proteins: a novel target class?

An allosteric conduit facilitates dynamic multisite substrate recognition by the SCF^Cdc4 ubiquitin ligase

Systematic chemical-genetic and chemical-chemical interaction datasets for prediction of compound synergism

Caenorhabditis elegans is a useful model for anthelmintic discovery

E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin

A predictive model for drug bioaccumulation and bioactivity in Caenorhabditis elegans

Chemical genetics reveals a complex functional ground state of neural stem cells

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases

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