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Reviews | 9 November 2020
A framework for understanding the functions of biomolecular condensates across scales
Nature Reviews Molecular Cell Biology , 1–21

Rights & permissionsfor article A framework for understanding the functions of biomolecular condensates across scales . Opens in a new window.
Research | 12 April 2009
The WAVE regulatory complex is inhibited
- Ayman M Ismail
- , Shae B Padrick
- , Baoyu Chen
- , Junko Umetani
- & Michael K Rosen
Nature Structural & Molecular Biology 16 , 561–563

Rights & permissionsfor article The WAVE regulatory complex is inhibited . Opens in a new window.
News and Views | 1 February 2002
Ignition of a cellular machine
- Mara Kreishman-Deltrick
- & Michael K. Rosen
Nature Cell Biology 4 , E31–E33

Rights & permissionsfor article Ignition of a cellular machine . Opens in a new window.
Research | 25 May 2020
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein
- Ruihui Zhang
- , Donghoon M. Lee
- , John R. Jimah
- , Nathalie Gerassimov
- , Changsong Yang
- , Sangjoon Kim
- , Delgermaa Luvsanjav
- , Jonathan Winkelman
- , Marcel Mettlen
- , Michael E. Abrams
- , Raghav Kalia
- , Peter Keene
- , Pratima Pandey
- , Benjamin Ravaux
- , Ji Hoon Kim
- , Jonathon A. Ditlev
- , Guofeng Zhang
- , Michael K. Rosen
- , Adam Frost
- , Neal M. Alto
- , Margaret Gardel
- , Sandra L. Schmid
- , Tatyana M. Svitkina
- , Jenny E. Hinshaw
- & Elizabeth H. Chen
Nature Cell Biology 22 , 674–688

Rights & permissionsfor article Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein . Opens in a new window.
Research | 7 March 2012
Phase transitions in the assembly of multivalent signalling proteins
- Pilong Li
- , Sudeep Banjade
- , Hui-Chun Cheng
- , Soyeon Kim
- , Baoyu Chen
- , Liang Guo
- , Marc Llaguno
- , Javoris V. Hollingsworth
- , David S. King
- , Salman F. Banani
- , Paul S. Russo
- , Qiu-Xing Jiang
- , B. Tracy Nixon
- & Michael K. Rosen
Nature 483 , 336–340

Rights & permissionsfor article Phase transitions in the assembly of multivalent signalling proteins . Opens in a new window.
Research | 20 June 2010
Rationally improving LOV domain–based photoswitches
Nature Methods 7 , 623–626

Rights & permissionsfor article Rationally improving LOV domain–based photoswitches . Opens in a new window.
Research | 23 July 2008
Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF_U
Nature 454 , 1009–1013

Rights & permissionsfor article Structural mechanism of WASP activation by the enterohaemorrhagic <i>E. coli</i> effector EspF<sub>U</sub> . Opens in a new window.
Research | 27 May 1999
Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein
Nature 399 , 379–383

Rights & permissionsfor article Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein . Opens in a new window.
Research | 1 March 2001
Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia
Nature Genetics 27 , 313–317

Rights & permissionsfor article Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia . Opens in a new window.
Research | 30 March 1995
Direct demonstration of an intramolecular SH2—phosphotyrosine interaction in the Crk protein
- Michael K. Rosen
- , Toshio Yamazaki
- , Gerald D. Gish
- , Cyril M. Kay
- , Tony Pawson
- & Lewis E. Kay
Nature 374 , 477–479

Rights & permissionsfor article Direct demonstration of an intramolecular SH2—phosphotyrosine interaction in the Crk protein . Opens in a new window.
Research | 18 May 2008
Internal dynamics control activation and activity of the autoinhibited Vav DH domain
Nature Structural & Molecular Biology 15 , 613–618

Rights & permissionsfor article Internal dynamics control activation and activity of the autoinhibited Vav DH domain . Opens in a new window.
Research | 19 June 1997
C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases
Nature 387 , 814–819

Rights & permissionsfor article C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases . Opens in a new window.
Research | 9 November 2016 | Open
Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
- Da Jia
- , Jin-San Zhang
- , Fang Li
- , Jing Wang
- , Zhihui Deng
- , Mark A. White
- , Douglas G. Osborne
- , Christine Phillips-Krawczak
- , Timothy S. Gomez
- , Haiying Li
- , Amika Singla
- , Ezra Burstein
- , Daniel D. Billadeau
- & Michael K. Rosen
Nature Communications 7 , 1–11

Rights & permissionsfor article Structural and mechanistic insights into regulation of the retromer coat by TBC1d5 . Opens in a new window.
Research | 7 March 2016 | Open
Data publication with the structural biology data grid supports live analysis
- Peter A. Meyer
- , Stephanie Socias
- , Jason Key
- , Elizabeth Ransey
- , Emily C. Tjon
- , Alejandro Buschiazzo
- , Ming Lei
- , Chris Botka
- , James Withrow
- , David Neau
- , Kanagalaghatta Rajashankar
- , Karen S. Anderson
- , Richard H. Baxter
- , Stephen C. Blacklow
- , Titus J. Boggon
- , Alexandre M. J. J. Bonvin
- , Dominika Borek
- , Tom J. Brett
- , Amedeo Caflisch
- , Chung-I Chang
- , Walter J. Chazin
- , Kevin D. Corbett
- , Michael S. Cosgrove
- , Sean Crosson
- , Sirano Dhe-Paganon
- , Enrico Di Cera
- , Catherine L. Drennan
- , Michael J. Eck
- , Brandt F. Eichman
- , Qing R. Fan
- , Adrian R. Ferré-D'Amaré
- , J. Christopher Fromme
- , K. Christopher Garcia
- , Rachelle Gaudet
- , Peng Gong
- , Stephen C. Harrison
- , Ekaterina E. Heldwein
- , Zongchao Jia
- , Robert J. Keenan
- , Andrew C. Kruse
- , Marc Kvansakul
- , Jason S. McLellan
- , Yorgo Modis
- , Yunsun Nam
- , Zbyszek Otwinowski
- , Emil F. Pai
- , Pedro José Barbosa Pereira
- , Carlo Petosa
- , C. S. Raman
- , Tom A. Rapoport
- , Antonina Roll-Mecak
- , Michael K. Rosen
- , Gabby Rudenko
- , Joseph Schlessinger
- , Thomas U. Schwartz
- , Yousif Shamoo
- , Holger Sondermann
- , Yizhi J. Tao
- , Niraj H. Tolia
- , Oleg V. Tsodikov
- , Kenneth D. Westover
- , Hao Wu
- , Ian Foster
- , James S. Fraser
- , Filipe R. N C. Maia
- , Tamir Gonen
- , Tom Kirchhausen
- , Kay Diederichs
- , Mercè Crosas
- & Piotr Sliz
Nature Communications 7 , 1–12

Rights & permissionsfor article Data publication with the structural biology data grid supports live analysis . Opens in a new window.
Reviews | 22 February 2017
Biomolecular condensates: organizers of cellular biochemistry
Nature Reviews Molecular Cell Biology 18 , 285–298

Rights & permissionsfor article Biomolecular condensates: organizers of cellular biochemistry . Opens in a new window.
Research | 20 July 2003
A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex
Nature Structural & Molecular Biology 10 , 591–598

Rights & permissionsfor article A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex . Opens in a new window.
Research | 28 August 2011
Mechanism of actin filament nucleation by the bacterial effector VopL
Nature Structural & Molecular Biology 18 , 1068–1074

Rights & permissionsfor article Mechanism of actin filament nucleation by the bacterial effector VopL . Opens in a new window.
Research | 5 January 2005
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain
Nature 433 , 488–494

Rights & permissionsfor article Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain . Opens in a new window.
Research | 9 March 2000
Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein
Nature 404 , 151–158

Rights & permissionsfor article Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein . Opens in a new window.
Research | 1 December 1998
Structure and mutagenesis of the Dbl homology domain
- Behzad Aghazadeh
- , Kejin Zhu
- , Terrance J. Kubiseski
- , Grace A. Liu
- , Tony Pawson
- , Yi Zheng
- & Michael K. Rosen
Nature Structural & Molecular Biology 5 , 1098–1107

Rights & permissionsfor article Structure and mutagenesis of the Dbl homology domain . Opens in a new window.
Research | 24 November 2010
Structure and control of the actin regulatory WAVE complex
Nature 468 , 533–538

Rights & permissionsfor article Structure and control of the actin regulatory WAVE complex . Opens in a new window.
Research | 4 July 2004
Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation
Nature Structural & Molecular Biology 11 , 747–755

Rights & permissionsfor article Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation . Opens in a new window.
Research | 6 July 2008
Estimation of the available free energy in a LOV2-Jα photoswitch
Nature Chemical Biology 4 , 491–497

Rights & permissionsfor article Estimation of the available free energy in a LOV2-Jα photoswitch . Opens in a new window.

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A framework for understanding the functions of biomolecular condensates across scales

The WAVE regulatory complex is inhibited

Ignition of a cellular machine

Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein

Phase transitions in the assembly of multivalent signalling proteins

Rationally improving LOV domain–based photoswitches

Structural mechanism of WASP activation by the enterohaemorrhagic E. coli effector EspF_U

Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein

Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

Direct demonstration of an intramolecular SH2—phosphotyrosine interaction in the Crk protein

Internal dynamics control activation and activity of the autoinhibited Vav DH domain

C-terminal binding domain of Rho GDP-dissociation inhibitor directs N-terminal inhibitory peptide to GTPases

Structural and mechanistic insights into regulation of the retromer coat by TBC1d5

Data publication with the structural biology data grid supports live analysis

Biomolecular condensates: organizers of cellular biochemistry

A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex

Mechanism of actin filament nucleation by the bacterial effector VopL

Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain

Autoinhibition and activation mechanisms of the Wiskott–Aldrich syndrome protein

Structure and mutagenesis of the Dbl homology domain

Structure and control of the actin regulatory WAVE complex

Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation

Estimation of the available free energy in a LOV2-Jα photoswitch

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