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Research | 14 January 2021 | Open
Continuous monitoring of neutrophils to lymphocytes ratio for estimating the onset, severity, and subsequent prognosis of immune related adverse events
- Ryosuke Matsukane
- , Hiroyuki Watanabe
- , Haruna Minami
- , Kojiro Hata
- , Kimitaka Suetsugu
- , Toshikazu Tsuji
- , Satohiro Masuda
- , Isamu Okamoto
- , Takashi Nakagawa
- , Takamichi Ito
- , Masatoshi Eto
- , Masaki Mori
- , Yoichi Nakanishi
- & Nobuaki Egashira
Scientific Reports 11 , 1–11

Rights & permissionsfor article Continuous monitoring of neutrophils to lymphocytes ratio for estimating the onset, severity, and subsequent prognosis of immune related adverse events . Opens in a new window.
Research | 23 October 2020 | Open
The endoluminal pressures during flexible gastrointestinal endoscopy
- Yuki Ushimaru
- , Kiyokazu Nakajima
- , Masashi Hirota
- , Yasuaki Miyazaki
- , Kotaro Yamashita
- , Takuro Saito
- , Koji Tanaka
- , Tomoki Makino
- , Tsuyoshi Takahashi
- , Yukinori Kurokawa
- , Makoto Yamasaki
- , Masaki Mori
- & Yuichiro Doki
Scientific Reports 10 , 1–9

Rights & permissionsfor article The endoluminal pressures during flexible gastrointestinal endoscopy . Opens in a new window.
Research | 19 October 2020
Prognostic impact of tumor microvessels in intrahepatic cholangiocarcinoma: association with tumor-infiltrating lymphocytes
- Kyohei Yugawa
- , Shinji Itoh
- , Tomoharu Yoshizumi
- , Norifumi Iseda
- , Takahiro Tomiyama
- , Takeo Toshima
- , Noboru Harada
- , Kenichi Kohashi
- , Yoshinao Oda
- & Masaki Mori
Modern Pathology , 1–10

Rights & permissionsfor article Prognostic impact of tumor microvessels in intrahepatic cholangiocarcinoma: association with tumor-infiltrating lymphocytes . Opens in a new window.
Research | 22 October 2020 | Open
Neuroepithelial cell competition triggers loss of cellular juvenescence
- Faidruz Azura Jam
- , Takao Morimune
- , Atsushi Tsukamura
- , Ayami Tano
- , Yuya Tanaka
- , Yasuhiro Mori
- , Takefumi Yamamoto
- , Masaki Nishimura
- , Ikuo Tooyama
- & Masaki Mori
Scientific Reports 10 , 1–14

Rights & permissionsfor article Neuroepithelial cell competition triggers loss of cellular juvenescence . Opens in a new window.
Research | 1 July 2020 | Open
The Geriatric Nutritional Risk Index predicts postoperative complications and prognosis in elderly patients with colorectal cancer after curative surgery
- Masaru Sasaki
- , Norikatsu Miyoshi
- , Shiki Fujino
- , Takayuki Ogino
- , Hidekazu Takahashi
- , Mamoru Uemura
- , Chu Matsuda
- , Hirofumi Yamamoto
- , Tsunekazu Mizushima
- , Masaki Mori
- & Yuichiro Doki
Scientific Reports 10 , 1–9

Rights & permissionsfor article The Geriatric Nutritional Risk Index predicts postoperative complications and prognosis in elderly patients with colorectal cancer after curative surgery . Opens in a new window.
Research | 24 January 2020 | Open
Theoretical analyses and experimental validation of the effects caused by the fluorinated substituent modification of DNA
- Jun Koseki
- , Masamitsu Konno
- , Ayumu Asai
- , Naohiro Horie
- , Kenta Tsunekuni
- , Koichi Kawamoto
- , Satoshi Obika
- , Yuichiro Doki
- , Masaki Mori
- & Hideshi Ishii
Scientific Reports 10 , 1–9

Rights & permissionsfor article Theoretical analyses and experimental validation of the effects caused by the fluorinated substituent modification of DNA . Opens in a new window.
Research | 19 February 2020 | Open
Some Gammaproteobacteria are enriched within CD14⁺ macrophages from intestinal lamina propria of Crohn’s disease patients versus mucus
- Yuki Sekido
- , Junichi Nishimura
- , Kazuhiro Nakano
- , Takeaki Osu
- , Cheryl-Emiliane T. Chow
- , Hiroshi Matsuno
- , Takayuki Ogino
- , Shiki Fujino
- , Norikatsu Miyoshi
- , Hidekazu Takahashi
- , Mamoru Uemura
- , Chu Matsuda
- , Hisako Kayama
- , Masaki Mori
- , Yuichiro Doki
- , Kiyoshi Takeda
- , Motoi Uchino
- , Hiroki Ikeuchi
- & Tsunekazu Mizushima
Scientific Reports 10 , 1–8

Rights & permissionsfor article Some <i>Gammaproteobacteria</i> are enriched within CD14<sup>+</sup> macrophages from intestinal lamina propria of Crohn’s disease patients versus mucus . Opens in a new window.
Research | 16 September 2019 | Open
¹⁸F-FDG uptake in PET/CT is a potential predictive biomarker of response to anti-PD-1 antibody therapy in non-small cell lung cancer
- Kazuki Takada
- , Gouji Toyokawa
- , Yasuto Yoneshima
- , Kentaro Tanaka
- , Isamu Okamoto
- , Mototsugu Shimokawa
- , Sho Wakasu
- , Akira Haro
- , Atsushi Osoegawa
- , Tetsuzo Tagawa
- , Yoshinao Oda
- , Yoichi Nakanishi
- & Masaki Mori
Scientific Reports 9 , 1–7

Rights & permissionsfor article <sup>18</sup>F-FDG uptake in PET/CT is a potential predictive biomarker of response to anti-PD-1 antibody therapy in non-small cell lung cancer . Opens in a new window.
Research | 16 October 2019 | Open
CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure
- Kenta Tsunekuni
- , Masamitsu Konno
- , Naotsugu Haraguchi
- , Jun Koseki
- , Ayumu Asai
- , Kazuaki Matsuoka
- , Takashi Kobunai
- , Teiji Takechi
- , Yuichiro Doki
- , Masaki Mori
- & Hideshi Ishii
Scientific Reports 9 , 1–8

Rights & permissionsfor article CD44/CD133-Positive Colorectal Cancer Stem Cells are Sensitive to Trifluridine Exposure . Opens in a new window.
Research | 29 August 2019 | Open
Distinct methylation levels of mature microRNAs in gastrointestinal cancers
- Masamitsu Konno
- , Jun Koseki
- , Ayumu Asai
- , Akira Yamagata
- , Teppei Shimamura
- , Daisuke Motooka
- , Daisuke Okuzaki
- , Koichi Kawamoto
- , Tsunekazu Mizushima
- , Hidetoshi Eguchi
- , Shuji Takiguchi
- , Taroh Satoh
- , Koshi Mimori
- , Takahiro Ochiya
- , Yuichiro Doki
- , Ken Ofusa
- , Masaki Mori
- & Hideshi Ishii
Nature Communications 10 , 1–7

Rights & permissionsfor article Distinct methylation levels of mature microRNAs in gastrointestinal cancers . Opens in a new window.
Research | 29 June 2020
Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor
- Kazuya Iwamoto
- , Hidekazu Takahashi
- , Daisuke Okuzaki
- , Hideo Osawa
- , Takayuki Ogino
- , Norikatsu Miyoshi
- , Mamoru Uemura
- , Chu Matsuda
- , Hirofumi Yamamoto
- , Tsunekazu Mizushima
- , Masaki Mori
- , Yuichiro Doki
- & Hidetoshi Eguchi
British Journal of Cancer 123 , 955–964

Rights & permissionsfor article Syntenin-1 promotes colorectal cancer stem cell expansion and chemoresistance by regulating prostaglandin E2 receptor . Opens in a new window.
Research | 24 June 2020 | Open
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer
- Yingsong Lin
- , Masahiro Nakatochi
- , Yasuyuki Hosono
- , Hidemi Ito
- , Yoichiro Kamatani
- , Akihito Inoko
- , Hiromi Sakamoto
- , Fumie Kinoshita
- , Yumiko Kobayashi
- , Hiroshi Ishii
- , Masato Ozaka
- , Takashi Sasaki
- , Masato Matsuyama
- , Naoki Sasahira
- , Manabu Morimoto
- , Satoshi Kobayashi
- , Taito Fukushima
- , Makoto Ueno
- , Shinichi Ohkawa
- , Naoto Egawa
- , Sawako Kuruma
- , Mitsuru Mori
- , Haruhisa Nakao
- , Yasushi Adachi
- , Masumi Okuda
- , Takako Osaki
- , Shigeru Kamiya
- , Chaochen Wang
- , Kazuo Hara
- , Yasuhiro Shimizu
- , Tatsuo Miyamoto
- , Yuko Hayashi
- , Hiromichi Ebi
- , Tomohiro Kohmoto
- , Issei Imoto
- , Yumiko Kasugai
- , Yoshinori Murakami
- , Masato Akiyama
- , Kazuyoshi Ishigaki
- , Koichi Matsuda
- , Makoto Hirata
- , Kazuaki Shimada
- , Takuji Okusaka
- , Takahisa Kawaguchi
- , Meiko Takahashi
- , Yoshiyuki Watanabe
- , Kiyonori Kuriki
- , Aya Kadota
- , Rieko Okada
- , Haruo Mikami
- , Toshiro Takezaki
- , Sadao Suzuki
- , Taiki Yamaji
- , Motoki Iwasaki
- , Norie Sawada
- , Atsushi Goto
- , Kengo Kinoshita
- , Nobuo Fuse
- , Fumiki Katsuoka
- , Atsushi Shimizu
- , Satoshi S. Nishizuka
- , Kozo Tanno
- , Ken Suzuki
- , Yukinori Okada
- , Momoko Horikoshi
- , Toshimasa Yamauchi
- , Takashi Kadowaki
- , Herbert Yu
- , Jun Zhong
- , Laufey T. Amundadottir
- , Yuichiro Doki
- , Hideshi Ishii
- , Hidetoshi Eguchi
- , David Bogumil
- , Christopher A. Haiman
- , Loic Le Marchand
- , Masaki Mori
- , Harvey Risch
- , Veronica W. Setiawan
- , Shoichiro Tsugane
- , Kenji Wakai
- , Teruhiko Yoshida
- , Fumihiko Matsuda
- , Michiaki Kubo
- , Shogo Kikuchi
- & Keitaro Matsuo
Nature Communications 11 , 1–12

Rights & permissionsfor article Genome-wide association meta-analysis identifies <i>GP2</i> gene risk variants for pancreatic cancer . Opens in a new window.
Research | 8 June 2020
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
- Kazuyoshi Ishigaki
- , Masato Akiyama
- , Masahiro Kanai
- , Atsushi Takahashi
- , Eiryo Kawakami
- , Hiroki Sugishita
- , Saori Sakaue
- , Nana Matoba
- , Siew-Kee Low
- , Yukinori Okada
- , Chikashi Terao
- , Tiffany Amariuta
- , Steven Gazal
- , Yuta Kochi
- , Momoko Horikoshi
- , Ken Suzuki
- , Kaoru Ito
- , Satoshi Koyama
- , Kouichi Ozaki
- , Shumpei Niida
- , Yasushi Sakata
- , Yasuhiko Sakata
- , Takashi Kohno
- , Kouya Shiraishi
- , Yukihide Momozawa
- , Makoto Hirata
- , Koichi Matsuda
- , Masashi Ikeda
- , Nakao Iwata
- , Shiro Ikegawa
- , Ikuyo Kou
- , Toshihiro Tanaka
- , Hidewaki Nakagawa
- , Akari Suzuki
- , Tomomitsu Hirota
- , Mayumi Tamari
- , Kazuaki Chayama
- , Daiki Miki
- , Masaki Mori
- , Satoshi Nagayama
- , Yataro Daigo
- , Yoshio Miki
- , Toyomasa Katagiri
- , Osamu Ogawa
- , Wataru Obara
- , Hidemi Ito
- , Teruhiko Yoshida
- , Issei Imoto
- , Takashi Takahashi
- , Chizu Tanikawa
- , Takao Suzuki
- , Nobuaki Sinozaki
- , Shiro Minami
- , Hiroki Yamaguchi
- , Satoshi Asai
- , Yasuo Takahashi
- , Ken Yamaji
- , Kazuhisa Takahashi
- , Tomoaki Fujioka
- , Ryo Takata
- , Hideki Yanai
- , Akihide Masumoto
- , Yukihiro Koretsune
- , Hiromu Kutsumi
- , Masahiko Higashiyama
- , Shigeo Murayama
- , Naoko Minegishi
- , Kichiya Suzuki
- , Kozo Tanno
- , Atsushi Shimizu
- , Taiki Yamaji
- , Motoki Iwasaki
- , Norie Sawada
- , Hirokazu Uemura
- , Keitaro Tanaka
- , Mariko Naito
- , Makoto Sasaki
- , Kenji Wakai
- , Shoichiro Tsugane
- , Masayuki Yamamoto
- , Kazuhiko Yamamoto
- , Yoshinori Murakami
- , Yusuke Nakamura
- , Soumya Raychaudhuri
- , Johji Inazawa
- , Toshimasa Yamauchi
- , Takashi Kadowaki
- , Michiaki Kubo
- & Yoichiro Kamatani
Nature Genetics 52 , 669–679

Rights & permissionsfor article Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases . Opens in a new window.
Research | 5 December 2018 | Open
Sox2 is associated with cancer stem-like properties in colorectal cancer
- Koki Takeda
- , Tsunekazu Mizushima
- , Yuhki Yokoyama
- , Haruka Hirose
- , Xin Wu
- , Yamin Qian
- , Katsuya Ikehata
- , Norikatsu Miyoshi
- , Hidekazu Takahashi
- , Naotsugu Haraguchi
- , Taishi Hata
- , Chu Matsuda
- , Yuichiro Doki
- , Masaki Mori
- & Hirofumi Yamamoto
Scientific Reports 8 , 1–9

Rights & permissionsfor article Sox2 is associated with cancer stem-like properties in colorectal cancer . Opens in a new window.
Research | 31 July 2017 | Open
Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions
- Takahiro Matsui
- , Hiroki Mizuno
- , Takao Sudo
- , Junichi Kikuta
- , Naotsugu Haraguchi
- , Jun-ichiro Ikeda
- , Tsunekazu Mizushima
- , Hirofumi Yamamoto
- , Eiichi Morii
- , Masaki Mori
- & Masaru Ishii
Scientific Reports 7 , 1–9

Rights & permissionsfor article Non-labeling multiphoton excitation microscopy as a novel diagnostic tool for discriminating normal tissue and colorectal cancer lesions . Opens in a new window.
Research | 17 January 2018 | Open
Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells
- Masamitsu Konno
- , Hidetoshi Matsui
- , Jun Koseki
- , Ayumu Asai
- , Yoshihiro Kano
- , Koichi Kawamoto
- , Naohiro Nishida
- , Daisuke Sakai
- , Toshihiro Kudo
- , Taroh Satoh
- , Yuichiro Doki
- , Masaki Mori
- & Hideshi Ishii
Scientific Reports 8 , 1–9

Rights & permissionsfor article Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells . Opens in a new window.
20 June 2017 | Open
Downregulation of serum metabolite GTA-446 as a novel potential marker for early detection of colorectal cancer
- Tsuyoshi Hata
- , Ichiro Takemasa
- , Hidekazu Takahashi
- , Naotsugu Haraguchi
- , Junichi Nishimura
- , Taishi Hata
- , Tsunekazu Mizushima
- , Yuichiro Doki
- & Masaki Mori
British Journal of Cancer 117 , 227–232

Rights & permissionsfor article Downregulation of serum metabolite GTA-446 as a novel potential marker for early detection of colorectal cancer . Opens in a new window.
Research | 10 January 2018 | Open
Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis
- Jun Koseki
- , Masamitsu Konno
- , Ayumu Asai
- , Hugh Colvin
- , Koichi Kawamoto
- , Naohiro Nishida
- , Daisuke Sakai
- , Toshihiro Kudo
- , Taroh Satoh
- , Yuichiro Doki
- , Masaki Mori
- & Hideshi Ishii
Scientific Reports 8 , 1–7

Rights & permissionsfor article Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis . Opens in a new window.
Correspondence | 11 April 2017
Robotic crowd biology with Maholo LabDroids
- Nozomu Yachie
- , Koichi Takahashi
- , Toshiaki Katayama
- , Takeshi Sakurada
- , Genki N. Kanda
- , Eiji Takagi
- , Takako Hirose
- , Tatsuo Katsura
- , Tetsuo Moriya
- , Hiroaki Kitano
- , Junichi Tsujii
- , Tomoyuki Shiraki
- , Hirokazu Kariyazaki
- , Motohisa Kamei
- , Noriko Abe
- , Takuya Fukuda
- , Yukiko Sawada
- , Yukio Hashiguchi
- , Kenji Matsukuma
- , Shinji Murai
- , Naoyuki Sasaki
- , Tatsuro Ipposhi
- , Hideo Urabe
- , Taku Kudo
- , Makoto Umeno
- , Seiki Ono
- , Kohei Miyauchi
- , Miki Nakamura
- , Takahiro Kizaki
- , Takashi Suyama
- , Tomohisa Hatta
- , Tohru Natsume
- , Tazro Ohta
- , Yosuke Ozawa
- , Shoji Ihara
- , Satoshi Tamaki
- , Erick Antezana
- , Alexander Garcia-Castro
- , Jean-Luc Perret
- , Soh Ishiguro
- , Hideto Mori
- , Daniel Evans-Yamamoto
- , Nanami Masuyama
- , Masaru Tomita
- , Toshiaki Katayama
- , Masaki Matsumoto
- , Hiroshi Nakayama
- , Ayaka Shirasawa
- , Kazutaka Shimbo
- , Naoyuki Yamada
- , Keiichi I. Nakayama
- , Takatsune Shimizu
- , Hideyuki Saya
- , Satoshi Yamashita
- , Takahide Matsushima
- , Hiroshi Asahara
- , Hidetoshi Eguchi
- , Manabu Mikamori
- , Masaki Mori
- & Tohru Natsume
Nature Biotechnology 35 , 310–312

Rights & permissionsfor article Robotic crowd biology with Maholo LabDroids . Opens in a new window.
Research | 9 June 2016 | Open
Rapid diagnosis of lymph node metastasis in breast cancer using a new fluorescent method with γ-glutamyl hydroxymethyl rhodamine green
- Yoshiaki Shinden
- , Hiroki Ueo
- , Taro Tobo
- , Ayako Gamachi
- , Mitsuaki Utou
- , Hisateru Komatsu
- , Sho Nambara
- , Tomoko Saito
- , Masami Ueda
- , Hidenari Hirata
- , Shotaro Sakimura
- , Yuki Takano
- , Ryutaro Uchi
- , Junji Kurashige
- , Sayuri Akiyoshi
- , Tomohiro Iguchi
- , Hidetoshi Eguchi
- , Keishi Sugimachi
- , Yoko Kubota
- , Yuichiro Kai
- , Kenji Shibuta
- , Yuko Kijima
- , Heiji Yoshinaka
- , Shoji Natsugoe
- , Masaki Mori
- , Yoshihiko Maehara
- , Masayo Sakabe
- , Mako Kamiya
- , John W. Kakareka
- , Thomas J. Pohida
- , Peter L. Choyke
- , Hisataka Kobayashi
- , Hiroaki Ueo
- , Yasuteru Urano
- & Koshi Mimori
Scientific Reports 6 , 1–7

Rights & permissionsfor article Rapid diagnosis of lymph node metastasis in breast cancer using a new fluorescent method with γ-glutamyl hydroxymethyl rhodamine green . Opens in a new window.
Research | 11 February 2016 | Open
A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells
- Jun Koseki
- , Hidetoshi Matsui
- , Masamitsu Konno
- , Naohiro Nishida
- , Koichi Kawamoto
- , Yoshihiro Kano
- , Masaki Mori
- , Yuichiro Doki
- & Hideshi Ishii
Scientific Reports 6 , 1–8

Rights & permissionsfor article A Trans-omics Mathematical Analysis Reveals Novel Functions of the Ornithine Metabolic Pathway in Cancer Stem Cells . Opens in a new window.
Research | 10 March 2020
Anti-glypican-1 antibody–drug conjugate is a potential therapy against pancreatic cancer
- Takahiko Nishigaki
- , Tsuyoshi Takahashi
- , Satoshi Serada
- , Minoru Fujimoto
- , Tomoharu Ohkawara
- , Hisashi Hara
- , Takahito Sugase
- , Toru Otsuru
- , Yurina Saito
- , Shigehiro Tsujii
- , Taisei Nomura
- , Koji Tanaka
- , Yasuhiro Miyazaki
- , Tomoki Makino
- , Yukinori Kurokawa
- , Kiyokazu Nakajima
- , Hidetoshi Eguchi
- , Makoto Yamasaki
- , Masaki Mori
- , Yuichiro Doki
- & Tetsuji Naka
British Journal of Cancer 122 , 1333–1341

Rights & permissionsfor article Anti-glypican-1 antibody–drug conjugate is a potential therapy against pancreatic cancer . Opens in a new window.
Research | 7 April 2014 | Open
Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen
- Yusuke Yoshioka
- , Nobuyoshi Kosaka
- , Yuki Konishi
- , Hideki Ohta
- , Hiroyuki Okamoto
- , Hikaru Sonoda
- , Ryoji Nonaka
- , Hirofumi Yamamoto
- , Hideshi Ishii
- , Masaki Mori
- , Koh Furuta
- , Takeshi Nakajima
- , Hiroshi Hayashi
- , Hajime Sugisaki
- , Hiroko Higashimoto
- , Takashi Kato
- , Fumitaka Takeshita
- & Takahiro Ochiya
Nature Communications 5 , 1–8

Rights & permissionsfor article Ultra-sensitive liquid biopsy of circulating extracellular vesicles using ExoScreen . Opens in a new window.
News and Views | 21 April 2015
Back to the stroma—the real villain in colorectal cancer?
- Hugh Colvin
- & Masaki Mori
Nature Reviews Gastroenterology & Hepatology 12 , 256–258

Rights & permissionsfor article Back to the stroma—the real villain in colorectal cancer? . Opens in a new window.
Research Highlights | 9 July 2013
EGFR gets in the way of microRNA biogenesis
Cell Research 23 , 1157–1158

Rights & permissionsfor article EGFR gets in the way of microRNA biogenesis . Opens in a new window.
Research | 13 July 2015 | Open
Rapid intraoperative visualization of breast lesions with γ-glutamyl hydroxymethyl rhodamine green
- Hiroki Ueo
- , Yoshiaki Shinden
- , Taro Tobo
- , Ayako Gamachi
- , Mitsuaki Udo
- , Hisateru Komatsu
- , Sho Nambara
- , Tomoko Saito
- , Masami Ueda
- , Hidenari Hirata
- , Shotaro Sakimura
- , Yuki Takano
- , Ryutaro Uchi
- , Junji Kurashige
- , Sayuri Akiyoshi
- , Tomohiro Iguchi
- , Hidetoshi Eguchi
- , Keishi Sugimachi
- , Yoko Kubota
- , Yuichiro Kai
- , Kenji Shibuta
- , Yuko Kijima
- , Heiji Yoshinaka
- , Shoji Natsugoe
- , Masaki Mori
- , Yoshihiko Maehara
- , Masayo Sakabe
- , Mako Kamiya
- , John W. Kakareka
- , Thomas J. Pohida
- , Peter L. Choyke
- , Hisataka Kobayashi
- , Hiroaki Ueo
- , Yasuteru Urano
- & Koshi Mimori
Scientific Reports 5 , 1–6

Rights & permissionsfor article Rapid intraoperative visualization of breast lesions with γ-glutamyl hydroxymethyl rhodamine green . Opens in a new window.
Research | 13 January 2015 | Open
A glucose carbonate apatite complex exhibits in vitro and in vivo anti-tumour effects
- Hirofumi Yamamoto
- , Xin Wu
- , Hiroyuki Nakanishi
- , Yuki Yamamoto
- , Mamoru Uemura
- , Taishi Hata
- , Junichi Nishimura
- , Ichiro Takemasa
- , Tsunekazu Mizushima
- , Jun-Ichi Sasaki
- , Satoshi Imazato
- , Nariaki Matsuura
- , Yuichiro Doki
- & Masaki Mori
Scientific Reports 5 , 1–7

Rights & permissionsfor article A glucose carbonate apatite complex exhibits <i>in vitro</i> and <i>in vivo</i> anti-tumour effects . Opens in a new window.
Research | 18 February 2020
miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells
- Yoshihiro Morimoto
- , Tsunekazu Mizushima
- , Xin Wu
- , Daisuke Okuzaki
- , Yuhki Yokoyama
- , Akira Inoue
- , Tsuyoshi Hata
- , Haruka Hirose
- , Yamin Qian
- , Jiaqi Wang
- , Norikatsu Miyoshi
- , Hidekazu Takahashi
- , Naotsugu Haraguchi
- , Chu Matsuda
- , Yuichiro Doki
- , Masaki Mori
- & Hirofumi Yamamoto
British Journal of Cancer 122 , 1037–1049

Rights & permissionsfor article miR-4711-5p regulates cancer stemness and cell cycle progression via KLF5, MDM2 and TFDP1 in colon cancer cells . Opens in a new window.
Research | 1 May 2005
A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease
- Shoji Seki
- , Yoshiharu Kawaguchi
- , Kazuhiro Chiba
- , Yasuo Mikami
- , Hideki Kizawa
- , Takeshi Oya
- , Futoshi Mio
- , Masaki Mori
- , Yoshinari Miyamoto
- , Ikuko Masuda
- , Tatsuhiko Tsunoda
- , Michihiro Kamata
- , Toshikazu Kubo
- , Yoshiaki Toyama
- , Tomoatsu Kimura
- , Yusuke Nakamura
- & Shiro Ikegawa
Nature Genetics 37 , 607–612

Rights & permissionsfor article A functional SNP in <i>CILP</i>, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease . Opens in a new window.
Research | 1 December 2006
Association study of COL9A2 with lumbar disc disease in the Japanese population
- Shoji Seki
- , Yoshiharu Kawaguchi
- , Masaki Mori
- , Futoshi Mio
- , Kazuhiro Chiba
- , Yasuo Mikami
- , Tatsuhiko Tsunoda
- , Toshikazu Kubo
- , Yoshiaki Toyama
- , Tomoatsu Kimura
- & Shiro Ikegawa
Journal of Human Genetics 51 , 1063–1067

Rights & permissionsfor article Association study of <i>COL9A2</i> with lumbar disc disease in the Japanese population . Opens in a new window.
4 April 2000 | Open
A dominant negative mutation of transforming growth factor- β receptor type II gene in microsatellite stable oesophageal carcinoma
- Shinji Tanaka
- , Masaki Mori
- , Ken-ichi Mafune
- , Shinji Ohno
- & Keizo Sugimachi
British Journal of Cancer 82 , 1557–1560

Rights & permissionsfor article A dominant negative mutation of transforming growth factor- <i>β</i> receptor type II gene in microsatellite stable oesophageal carcinoma . Opens in a new window.
16 July 2002
Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer
- Shin Sasaki
- , Tatsuya Nakamura
- , Hirofumi Arakawa
- , Masaki Mori
- , Toshiaki Watanabe
- , Hirokazu Nagawa
- & Carlo M Croce
Oncogene 21 , 5024–5030

Rights & permissionsfor article Isolation and characterization of a novel gene, hRFI, preferentially expressed in esophageal cancer . Opens in a new window.
15 February 2011 | Open
Gain-of-function oncogenic mutations in TP53 enhance defined factor-mediated cellular reprogramming
- Jeong Ho Moon
- , Hideshi Ishii
- , Dyah Laksmi Dewi
- , Yoshihiro Kano
- , Kazuyoshi Yamamoto
- , Shinpei Nishikawa
- , Yoshiyuki Fujiwara
- , Yuichiro Doki
- & Masaki Mori
Nature Precedings , 1–1

Rights & permissionsfor article Gain-of-function oncogenic mutations in TP53 enhance defined factor-mediated cellular reprogramming . Opens in a new window.
1 June 1997
p27 expression and gastric carcinoma
- Masaki Mori
- , Koshi Mimori
- , Takeshi Shiraishi
- , Shinji Tanaka
- , Hiroaki Ueo
- , Keizo Sugimachi
- & Tsuyoshi Akiyoshi
Nature Medicine 3 , 593–593

Rights & permissionsfor article p27 expression and gastric carcinoma . Opens in a new window.
1 July 1985
COMPARISON OF SURFACE DIFFERENTIATION ANTIGENS BETWEEN SEPARATED HGPRT-POSITIVE AND NEGATIVE T-CELL POPULATIONS FROM TWO LESCH-NYHAN HETEROZYGOTES: 233
Pediatric Research 19 , 782–782

Rights & permissionsfor article COMPARISON OF SURFACE DIFFERENTIATION ANTIGENS BETWEEN SEPARATED HGPRT-POSITIVE AND NEGATIVE T-CELL POPULATIONS FROM TWO LESCH-NYHAN HETEROZYGOTES: 233 . Opens in a new window.
29 May 2003
MAL gene expression in esophageal cancer suppresses motility, invasion and tumorigenicity and enhances apoptosis through the Fas pathway
- Koshi Mimori
- , Takeshi Shiraishi
- , Kohjiro Mashino
- , Hideto Sonoda
- , Keishi Yamashita
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- , Takaaki Masuda
- , Tohru Utsunomiya
- , Miguel A Alonso
- , Hiroshi Inoue
- & Masaki Mori
Oncogene 22 , 3463–3471

Rights & permissionsfor article <i>MAL</i> gene expression in esophageal cancer suppresses motility, invasion and tumorigenicity and enhances apoptosis through the Fas pathway . Opens in a new window.
Research | 20 December 2019 | Open
TAS-116 inhibits oncogenic KIT signalling on the Golgi in both imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours
- Yurina Saito
- , Tsuyoshi Takahashi
- , Yuuki Obata
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- , Fumio Nakagawa
- , Satoshi Serada
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- , Takahito Sugase
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- , Tomoki Makino
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- , Makoto Yamasaki
- , Seiichi Hirota
- , Tetsuji Naka
- , Masaki Mori
- & Yuichiro Doki
British Journal of Cancer 122 , 658–667

Rights & permissionsfor article TAS-116 inhibits oncogenic KIT signalling on the Golgi in both imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours . Opens in a new window.
Research | 31 October 2019 | Open
Serum milk fat globule-EGF factor 8 (MFG-E8) as a diagnostic and prognostic biomarker in patients with hepatocellular carcinoma
- Tomonari Shimagaki
- , Sachiyo Yoshio
- , Hironari Kawai
- , Yuzuru Sakamoto
- , Hiroyoshi Doi
- , Michitaka Matsuda
- , Taizo Mori
- , Yosuke Osawa
- , Moto Fukai
- , Takeshi Yoshida
- , Yunfei Ma
- , Tomoyuki Akita
- , Junko Tanaka
- , Akinobu Taketomi
- , Rikinari Hanayama
- , Tomoharu Yoshizumi
- , Masaki Mori
- & Tatsuya Kanto
Scientific Reports 9 , 1–12

Rights & permissionsfor article Serum milk fat globule-EGF factor 8 (MFG-E8) as a diagnostic and prognostic biomarker in patients with hepatocellular carcinoma . Opens in a new window.
Research | 28 June 2019 | Open
Principles and development of collagen-mediated tissue fusion induced by laser irradiation
- Shun Sasaki
- , Tetsuo Ikeda
- , Shin-ichiro Okihara
- , Shotaro Nishimura
- , Ryu Nakadate
- , Hiroshi Saeki
- , Eiji Oki
- , Masaki Mori
- , Makoto Hashizume
- & Yoshihiko Maehara
Scientific Reports 9 , 1–10

Rights & permissionsfor article Principles and development of collagen-mediated tissue fusion induced by laser irradiation . Opens in a new window.
Research | 24 January 2019 | Open
The rice CYP78A gene BSR2 confers resistance to Rhizoctonia solani and affects seed size and growth in Arabidopsis and rice
- Satoru Maeda
- , Joseph G. Dubouzet
- , Youichi Kondou
- , Yusuke Jikumaru
- , Shigemi Seo
- , Kenji Oda
- , Minami Matsui
- , Hirohiko Hirochika
- & Masaki Mori
Scientific Reports 9 , 1–14

Rights & permissionsfor article The rice <i>CYP78A</i> gene <i>BSR2</i> confers resistance to <i>Rhizoctonia solani</i> and affects seed size and growth in <i>Arabidopsis</i> and rice . Opens in a new window.
Research | 13 November 2018 | Open
Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells
- Keisuke Tamari
- , Masamitsu Konno
- , Ayumu Asai
- , Jun Koseki
- , Kazuhiko Hayashi
- , Koichi Kawamoto
- , Noriyuki Murai
- , Senya Matsufuji
- , Fumiaki Isohashi
- , Taroh Satoh
- , Noriko Goto
- , Shinji Tanaka
- , Yuichiro Doki
- , Masaki Mori
- , Kazuhiko Ogawa
- & Hideshi Ishii
Cell Death Discovery 4 , 1–9

Rights & permissionsfor article Polyamine flux suppresses histone lysine demethylases and enhances <i>ID1</i> expression in cancer stem cells . Opens in a new window.
Research | 15 February 2018 | Open
Identification of juvenility-associated genes in the mouse hepatocytes and cardiomyocytes
Scientific Reports 8 , 1–12

Rights & permissionsfor article Identification of juvenility-associated genes in the mouse hepatocytes and cardiomyocytes . Opens in a new window.
Research | 23 July 2018 | Open
A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer
- Tomoko Saito
- , Atsushi Niida
- , Ryutaro Uchi
- , Hidenari Hirata
- , Hisateru Komatsu
- , Shotaro Sakimura
- , Shuto Hayashi
- , Sho Nambara
- , Yosuke Kuroda
- , Shuhei Ito
- , Hidetoshi Eguchi
- , Takaaki Masuda
- , Keishi Sugimachi
- , Taro Tobo
- , Haruto Nishida
- , Tsutomu Daa
- , Kenichi Chiba
- , Yuichi Shiraishi
- , Tetsuichi Yoshizato
- , Masaaki Kodama
- , Tadayoshi Okimoto
- , Kazuhiro Mizukami
- , Ryo Ogawa
- , Kazuhisa Okamoto
- , Mitsutaka Shuto
- , Kensuke Fukuda
- , Yusuke Matsui
- , Teppei Shimamura
- , Takanori Hasegawa
- , Yuichiro Doki
- , Satoshi Nagayama
- , Kazutaka Yamada
- , Mamoru Kato
- , Tatsuhiro Shibata
- , Masaki Mori
- , Hiroyuki Aburatani
- , Kazunari Murakami
- , Yutaka Suzuki
- , Seishi Ogawa
- , Satoru Miyano
- & Koshi Mimori
Nature Communications 9 , 1–11

Rights & permissionsfor article A temporal shift of the evolutionary principle shaping intratumor heterogeneity in colorectal cancer . Opens in a new window.
Research | 22 March 2018
Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug
- Naoki Shinno
- , Hirokazu Kimura
- , Ryota Sada
- , Shuji Takiguchi
- , Masaki Mori
- , Katsumi Fumoto
- , Yuichiro Doki
- & Akira Kikuchi
Oncogene 37 , 3471–3484

Rights & permissionsfor article Activation of the Dickkopf1-CKAP4 pathway is associated with poor prognosis of esophageal cancer and anti-CKAP4 antibody may be a new therapeutic drug . Opens in a new window.
Research | 8 August 2018
Poly(ethylene glycol)–poly(lysine) block copolymer–ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells
- Reishi Toshiyama
- , Masamitsu Konno
- , Hidetoshi Eguchi
- , Hiroyasu Takemoto
- , Takehiro Noda
- , Ayumu Asai
- , Jun Koseki
- , Naotsugu Haraguchi
- , Yuji Ueda
- , Katsunori Matsushita
- , Kei Asukai
- , Tomofumi Ohashi
- , Yoshifumi Iwagami
- , Daisaku Yamada
- , Daisuke Sakai
- , Tadafumi Asaoka
- , Toshihiro Kudo
- , Koichi Kawamoto
- , Kunihito Gotoh
- , Shogo Kobayashi
- , Taroh Satoh
- , Yuichiro Doki
- , Nobuhiro Nishiyama
- , Masaki Mori
- & Hideshi Ishii
Oncogene 38 , 244–260

Rights & permissionsfor article Poly(ethylene glycol)–poly(lysine) block copolymer–ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells . Opens in a new window.
Research | 20 July 2017 | Open
Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism
- Naoki Yamada
- , Yuto Honda
- , Hiroyasu Takemoto
- , Takahiro Nomoto
- , Makoto Matsui
- , Keishiro Tomoda
- , Masamitsu Konno
- , Hideshi Ishii
- , Masaki Mori
- & Nobuhiro Nishiyama
Scientific Reports 7 , 1–10

Rights & permissionsfor article Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism . Opens in a new window.
3 May 2016 | Open
Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer
- Hideki Osawa
- , Hidekazu Takahashi
- , Junichi Nishimura
- , Katsuya Ohta
- , Naotsugu Haraguchi
- , Taishi Hata
- , Hirofumi Yamamoto
- , Tsunekazu Mizushima
- , Ichiro Takemasa
- , Yuichiro Doki
- & Masaki Mori
British Journal of Cancer 114 , 1251–1260

Rights & permissionsfor article Full-length LGR5-positive cells have chemoresistant characteristics in colorectal cancer . Opens in a new window.
Research | 15 February 2017 | Open
MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma
- Manabu Mikamori
- , Daisaku Yamada
- , Hidetoshi Eguchi
- , Shinichiro Hasegawa
- , Tomoya Kishimoto
- , Yoshito Tomimaru
- , Tadafumi Asaoka
- , Takehiro Noda
- , Hiroshi Wada
- , Koichi Kawamoto
- , Kunihito Gotoh
- , Yutaka Takeda
- , Masahiro Tanemura
- , Masaki Mori
- & Yuichiro Doki
Scientific Reports 7 , 1–14

Rights & permissionsfor article MicroRNA-155 Controls Exosome Synthesis and Promotes Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma . Opens in a new window.
Research | 7 December 2016 | Open
Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer
- Masaaki Miyo
- , Masamitsu Konno
- , Naohiro Nishida
- , Toshinori Sueda
- , Kozo Noguchi
- , Hidetoshi Matsui
- , Hugh Colvin
- , Koichi Kawamoto
- , Jun Koseki
- , Naotsugu Haraguchi
- , Junichi Nishimura
- , Taishi Hata
- , Noriko Gotoh
- , Fumio Matsuda
- , Taroh Satoh
- , Tsunekazu Mizushima
- , Hiroshi Shimizu
- , Yuichiro Doki
- , Masaki Mori
- & Hideshi Ishii
Scientific Reports 6 , 1–13

Rights & permissionsfor article Metabolic Adaptation to Nutritional Stress in Human Colorectal Cancer . Opens in a new window.
Research | 11 January 2016 | Open
BRAF^V600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells
- Toshinori Sueda
- , Daisuke Sakai
- , Koichi Kawamoto
- , Masamitsu Konno
- , Naohiro Nishida
- , Jun Koseki
- , Hugh Colvin
- , Hidekazu Takahashi
- , Naotsugu Haraguchi
- , Junichi Nishimura
- , Taishi Hata
- , Ichiro Takemasa
- , Tsunekazu Mizushima
- , Hirofumi Yamamoto
- , Taroh Satoh
- , Yuichiro Doki
- , Masaki Mori
- & Hideshi Ishii
Scientific Reports 6 , 1–14

Rights & permissionsfor article BRAF<sup>V600E</sup> inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells . Opens in a new window.

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