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Showing 1–11 of 11 results
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Research | | Open
Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease
- Jonas B. Nielsen
- , Oren Rom
- , Ida Surakka
- , Sarah E. Graham
- , Wei Zhou
- , Tanmoy Roychowdhury
- , Lars G. Fritsche
- , Sarah A. Gagliano Taliun
- , Carlo Sidore
- , Yuhao Liu
- , Maiken E. Gabrielsen
- , Anne Heidi Skogholt
- , Brooke Wolford
- , William Overton
- , Ying Zhao
- , Jin Chen
- , He Zhang
- , Whitney E. Hornsby
- , Akua Acheampong
- , Austen Grooms
- , Amanda Schaefer
- , Gregory J. M. Zajac
- , Luis Villacorta
- , Jifeng Zhang
- , Ben Brumpton
- , Mari Løset
- , Vivek Rai
- , Pia R. Lundegaard
- , Morten S. Olesen
- , Kent D. Taylor
- , Nicholette D. Palmer
- , Yii-Der Chen
- , Seung H. Choi
- , Steven A. Lubitz
- , Patrick T. Ellinor
- , Kathleen C. Barnes
- , Michelle Daya
- , Nicholas Rafaels
- , Scott T. Weiss
- , Jessica Lasky-Su
- , Russell P. Tracy
- , Ramachandran S. Vasan
- , L. Adrienne Cupples
- , Rasika A. Mathias
- , Lisa R. Yanek
- , Lewis C. Becker
- , Patricia A. Peyser
- , Lawrence F. Bielak
- , Jennifer A. Smith
- , Stella Aslibekyan
- , Bertha A. Hidalgo
- , Donna K. Arnett
- , Marguerite R. Irvin
- , James G. Wilson
- , Solomon K. Musani
- , Adolfo Correa
- , Stephen S. Rich
- , Xiuqing Guo
- , Jerome I. Rotter
- , Barbara A. Konkle
- , Jill M. Johnsen
- , Allison E. Ashley-Koch
- , Marilyn J. Telen
- , Vivien A. Sheehan
- , John Blangero
- , Joanne E. Curran
- , Juan M. Peralta
- , Courtney Montgomery
- , Wayne H-H Sheu
- , Ren-Hua Chung
- , Karen Schwander
- , Seyed M. Nouraie
- , Victor R. Gordeuk
- , Yingze Zhang
- , Charles Kooperberg
- , Alexander P. Reiner
- , Rebecca D. Jackson
- , Eugene R. Bleecker
- , Deborah A. Meyers
- , Xingnan Li
- , Sayantan Das
- , Ketian Yu
- , Jonathon LeFaive
- , Albert Smith
- , Tom Blackwell
- , Daniel Taliun
- , Sebastian Zollner
- , Lukas Forer
- , Sebastian Schoenherr
- , Christian Fuchsberger
- , Anita Pandit
- , Matthew Zawistowski
- , Sachin Kheterpal
- , Chad M. Brummett
- , Pradeep Natarajan
- , David Schlessinger
- , Seunggeun Lee
- , Hyun Min Kang
- , Francesco Cucca
- , Oddgeir L. Holmen
- , Bjørn O. Åsvold
- , Michael Boehnke
- , Sekar Kathiresan
- , Goncalo R. Abecasis
- , Y. Eugene Chen
- , Cristen J. Willer
- & Kristian Hveem
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Research | | Open
MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk
- Ida Surakka
- , Lars G. Fritsche
- , Wei Zhou
- , Joshua Backman
- , Jack A. Kosmicki
- , Haocheng Lu
- , Ben Brumpton
- , Jonas B. Nielsen
- , Maiken E. Gabrielsen
- , Anne Heidi Skogholt
- , Brooke Wolford
- , Sarah E. Graham
- , Y. Eugene Chen
- , Seunggeun Lee
- , Hyun Min Kang
- , Arnulf Langhammer
- , Siri Forsmo
- , Bjørn O. Åsvold
- , Unnur Styrkarsdottir
- , Hilma Holm
- , Daniel Gudbjartsson
- , Kari Stefansson
- , Aris Baras
- , Xiaodong Bai
- , Suganthi Balasubramanian
- , Leland Barnard
- , Andrew Blumenfeld
- , Michael Cantor
- , Giovanni Coppola
- , Aris Economides
- , Gisu Eom
- , Lukas Habegger
- , Young Hahn
- , Alicia Hawes
- , Marcus B. Jones
- , Shareef Khalid
- , Luca A. Lotta
- , Evan K. Maxwell
- , Lyndon J. Mitnaul
- , John D. Overton
- , Jeffrey G. Reid
- , Manuel Allen Revez Ferreira
- , William Salerno
- , Deepika Sharma
- , Alan Shuldiner
- , Jeffrey C. Staples
- , Ashish Yadav
- , Goncalo R. Abecasis
- , Kristian Hveem
- & Cristen J. Willer
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Research | | Open
GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse association with thyroid cancer
- Wei Zhou
- , Ben Brumpton
- , Omer Kabil
- , Julius Gudmundsson
- , Gudmar Thorleifsson
- , Josh Weinstock
- , Matthew Zawistowski
- , Jonas B. Nielsen
- , Layal Chaker
- , Marco Medici
- , Alexander Teumer
- , Silvia Naitza
- , Serena Sanna
- , Ulla T. Schultheiss
- , Anne Cappola
- , Juha Karjalainen
- , Mitja Kurki
- , Morgan Oneka
- , Peter Taylor
- , Lars G. Fritsche
- , Sarah E. Graham
- , Brooke N. Wolford
- , William Overton
- , Humaira Rasheed
- , Eirin B. Haug
- , Maiken E. Gabrielsen
- , Anne Heidi Skogholt
- , Ida Surakka
- , George Davey Smith
- , Anita Pandit
- , Tanmoy Roychowdhury
- , Whitney E. Hornsby
- , Jon G. Jonasson
- , Leigha Senter
- , Sandya Liyanarachchi
- , Matthew D. Ringel
- , Li Xu
- , Lambertus A. Kiemeney
- , Huiling He
- , Romana T. Netea-Maier
- , Jose I. Mayordomo
- , Theo S. Plantinga
- , Jon Hrafnkelsson
- , Hannes Hjartarson
- , Erich M. Sturgis
- , Aarno Palotie
- , Mark Daly
- , Cintia E. Citterio
- , Peter Arvan
- , Chad M. Brummett
- , Michael Boehnke
- , Albert de la Chapelle
- , Kari Stefansson
- , Kristian Hveem
- , Cristen J. Willer
- & Bjørn Olav Åsvold
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Research |
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Research | | Open
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Research | | Open
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis
- Sarah E. Graham
- , Jonas B. Nielsen
- , Matthew Zawistowski
- , Wei Zhou
- , Lars G. Fritsche
- , Maiken E. Gabrielsen
- , Anne Heidi Skogholt
- , Ida Surakka
- , Whitney E. Hornsby
- , Damian Fermin
- , Daniel B. Larach
- , Sachin Kheterpal
- , Chad M. Brummett
- , Seunggeun Lee
- , Hyun Min Kang
- , Goncalo R. Abecasis
- , Solfrid Romundstad
- , Stein Hallan
- , Matthew G. Sampson
- , Kristian Hveem
- & Cristen J. Willer
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Research |
Biological and clinical insights from genetics of insomnia symptoms
- Jacqueline M. Lane
- , Samuel E. Jones
- , Hassan S. Dashti
- , Andrew R. Wood
- , Krishna G. Aragam
- , Vincent T. van Hees
- , Linn B. Strand
- , Bendik S. Winsvold
- , Heming Wang
- , Jack Bowden
- , Yanwei Song
- , Krunal Patel
- , Simon G. Anderson
- , Robin N. Beaumont
- , David A. Bechtold
- , Brian E. Cade
- , Mary Haas
- , Sekar Kathiresan
- , Max A. Little
- , Annemarie I. Luik
- , Andrew S. Loudon
- , Shaun Purcell
- , Rebecca C. Richmond
- , Frank A. J. L. Scheer
- , Barbara Schormair
- , Jessica Tyrrell
- , John W. Winkelman
- , Juliane Winkelmann
- , Amy E. Martinsen
- , Anne H. Skogholt
- , Ben Brumpton
- , Bendik S. Winsvold
- , Børge Sivertsen
- , Cristen J. Willer
- , Daniela Bragantini
- , Håvard Kallestad
- , Imre Janszky
- , Ismail C. Guzey
- , John-Anker Zwart
- , Jonas B. Nielsen
- , Kristian B. Nilsen
- , Kristian Hveem
- , Lars Fritsche
- , Linda M. Pedersen
- , Linn B. Strand
- , Maiken E. Gabrielsen
- , Marianne B. Johnsen
- , Marie U. Lie
- , Morten Engstrøm
- , Trond Sand
- , Wei Zhou
- , Kristian Hveem
- , Chen Zhao
- , Jonas B. Nielsen
- , Cristen J. Willer
- , Susan Redline
- , Kai Spiegelhalder
- , Simon D. Kyle
- , David W. Ray
- , John-Anker Zwart
- , Ben Brumpton
- , Timothy M. Frayling
- , Deborah A. Lawlor
- , Martin K. Rutter
- , Michael N. Weedon
- & Richa Saxena
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Research |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
- Wei Zhou
- , Jonas B. Nielsen
- , Lars G. Fritsche
- , Rounak Dey
- , Maiken E. Gabrielsen
- , Brooke N. Wolford
- , Jonathon LeFaive
- , Peter VandeHaar
- , Sarah A. Gagliano
- , Aliya Gifford
- , Lisa A. Bastarache
- , Wei-Qi Wei
- , Joshua C. Denny
- , Maoxuan Lin
- , Kristian Hveem
- , Hyun Min Kang
- , Goncalo R. Abecasis
- , Cristen J. Willer
- & Seunggeun Lee
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Research |
Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
- Jonas B. Nielsen
- , Rosa B. Thorolfsdottir
- , Lars G. Fritsche
- , Wei Zhou
- , Morten W. Skov
- , Sarah E. Graham
- , Todd J. Herron
- , Shane McCarthy
- , Ellen M. Schmidt
- , Gardar Sveinbjornsson
- , Ida Surakka
- , Michael R. Mathis
- , Masatoshi Yamazaki
- , Ryan D. Crawford
- , Maiken E. Gabrielsen
- , Anne Heidi Skogholt
- , Oddgeir L. Holmen
- , Maoxuan Lin
- , Brooke N. Wolford
- , Rounak Dey
- , Håvard Dalen
- , Patrick Sulem
- , Jonathan H. Chung
- , Joshua D. Backman
- , David O. Arnar
- , Unnur Thorsteinsdottir
- , Aris Baras
- , Colm O’Dushlaine
- , Anders G. Holst
- , Xiaoquan Wen
- , Whitney Hornsby
- , Frederick E. Dewey
- , Michael Boehnke
- , Sachin Kheterpal
- , Bhramar Mukherjee
- , Seunggeun Lee
- , Hyun M. Kang
- , Hilma Holm
- , Jacob Kitzman
- , Jordan A. Shavit
- , José Jalife
- , Chad M. Brummett
- , Tanya M. Teslovich
- , David J. Carey
- , Daniel F. Gudbjartsson
- , Kari Stefansson
- , Gonçalo R. Abecasis
- , Kristian Hveem
- & Cristen J. Willer
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Research | | Open
Investigating the causal effect of smoking on hay fever and asthma: a Mendelian randomization meta-analysis in the CARTA consortium
- Tea Skaaby
- , Amy E. Taylor
- , Rikke K. Jacobsen
- , Lavinia Paternoster
- , Betina H. Thuesen
- , Tarunveer S. Ahluwalia
- , Sofus C. Larsen
- , Ang Zhou
- , Andrew Wong
- , Maiken E. Gabrielsen
- , Johan H. Bjørngaard
- , Claudia Flexeder
- , Satu Männistö
- , Rebecca Hardy
- , Diana Kuh
- , Sarah J. Barry
- , Line Tang Møllehave
- , Charlotte Cerqueira
- , Nele Friedrich
- , Tobias N. Bonten
- , Raymond Noordam
- , Dennis O. Mook-Kanamori
- , Christian Taube
- , Leon E. Jessen
- , Alex McConnachie
- , Naveed Sattar
- , Mark N. Upton
- , Charles McSharry
- , Klaus Bønnelykke
- , Hans Bisgaard
- , Holger Schulz
- , Konstantin Strauch
- , Thomas Meitinger
- , Annette Peters
- , Harald Grallert
- , Ellen A. Nohr
- , Mika Kivimaki
- , Meena Kumari
- , Uwe Völker
- , Matthias Nauck
- , Henry Völzke
- , Chris Power
- , Elina Hyppönen
- , Torben Hansen
- , Torben Jørgensen
- , Oluf Pedersen
- , Veikko Salomaa
- , Niels Grarup
- , Arnulf Langhammer
- , Pål R. Romundstad
- , Frank Skorpen
- , Jaakko Kaprio
- , Marcus R Munafò
- & Allan Linneberg
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Research |
Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology
- Manuel A Ferreira
- , Judith M Vonk
- , Hansjörg Baurecht
- , Ingo Marenholz
- , Chao Tian
- , Joshua D Hoffman
- , Quinta Helmer
- , Annika Tillander
- , Vilhelmina Ullemar
- , Jenny van Dongen
- , Yi Lu
- , Franz Rüschendorf
- , Jorge Esparza-Gordillo
- , Chris W Medway
- , Edward Mountjoy
- , Kimberley Burrows
- , Oliver Hummel
- , Sarah Grosche
- , Ben M Brumpton
- , John S Witte
- , Jouke-Jan Hottenga
- , Gonneke Willemsen
- , Jie Zheng
- , Elke Rodríguez
- , Melanie Hotze
- , Andre Franke
- , Joana A Revez
- , Jonathan Beesley
- , Melanie C Matheson
- , Shyamali C Dharmage
- , Lisa M Bain
- , Lars G Fritsche
- , Maiken E Gabrielsen
- , Brunilda Balliu
- , Jonas B Nielsen
- , Wei Zhou
- , Kristian Hveem
- , Arnulf Langhammer
- , Oddgeir L Holmen
- , Mari Løset
- , Gonçalo R Abecasis
- , Cristen J Willer
- , Andreas Arnold
- , Georg Homuth
- , Carsten O Schmidt
- , Philip J Thompson
- , Nicholas G Martin
- , David L Duffy
- , Natalija Novak
- , Holger Schulz
- , Stefan Karrasch
- , Christian Gieger
- , Konstantin Strauch
- , Ronald B Melles
- , David A Hinds
- , Norbert Hübner
- , Stephan Weidinger
- , Patrik K E Magnusson
- , Rick Jansen
- , Eric Jorgenson
- , Young-Ae Lee
- , Dorret I Boomsma
- , Catarina Almqvist
- , Robert Karlsson
- , Gerard H Koppelman
- & Lavinia Paternoster
