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Research | 9 December 2020 | Open
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection
- Niyati Desai
- , Azfar Neyaz
- , Annamaria Szabolcs
- , Angela R. Shih
- , Jonathan H. Chen
- , Vishal Thapar
- , Linda T. Nieman
- , Alexander Solovyov
- , Arnav Mehta
- , David J. Lieb
- , Anupriya S. Kulkarni
- , Christopher Jaicks
- , Katherine H. Xu
- , Michael J. Raabe
- , Christopher J. Pinto
- , Dejan Juric
- , Ivan Chebib
- , Robert B. Colvin
- , Arthur Y. Kim
- , Robert Monroe
- , Sarah E. Warren
- , Patrick Danaher
- , Jason W. Reeves
- , Jingjing Gong
- , Erroll H. Rueckert
- , Benjamin D. Greenbaum
- , Nir Hacohen
- , Stephen M. Lagana
- , Miguel N. Rivera
- , Lynette M. Sholl
- , James R. Stone
- , David T. Ting
- & Vikram Deshpande
Nature Communications 11 , 1–15

Rights & permissionsfor article Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection . Opens in a new window.
Research | 19 June 2020
In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19
Modern Pathology 33 , 2104–2114

Rights & permissionsfor article In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19 . Opens in a new window.
Amendments and Corrections | 9 June 2017 | Open
Erratum: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2
- Haikuo Zhang
- , Christine Fillmore Brainson
- , Shohei Koyama
- , Amanda J. Redig
- , Ting Chen
- , Shuai Li
- , Manav Gupta
- , Carolina Garcia-de-Alba
- , Margherita Paschini
- , Grit S. Herter-Sprie
- , Gang Lu
- , Xin Zhang
- , Bryan P Marsh
- , Stephanie J. Tuminello
- , Chunxiao Xu
- , Zhao Chen
- , Xiaoen Wang
- , Esra A. Akbay
- , Mei Zheng
- , Sangeetha Palakurthi
- , Lynette M. Sholl
- , Anil K. Rustgi
- , David J. Kwiatkowski
- , J. Alan Diehl
- , Adam J. Bass
- , Norman E. Sharpless
- , Glenn Dranoff
- , Peter S. Hammerman
- , Hongbin Ji
- , Nabeel Bardeesy
- , Dieter Saur
- , Hideo Watanabe
- , Carla F. Kim
- & Kwok-Kin Wong
Nature Communications 8 , 1–1

Rights & permissionsfor article Erratum: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2 . Opens in a new window.
Reviews | 11 September 2020
Strategies for the successful implementation of plasma-based NSCLC genotyping in clinical practice
Nature Reviews Clinical Oncology 18 , 56–62

Rights & permissionsfor article Strategies for the successful implementation of plasma-based NSCLC genotyping in clinical practice . Opens in a new window.
Research | 28 August 2020
Intestinal metaplasia of the urinary tract harbors potentially oncogenic genetic variants
Modern Pathology 34 , 457–468

Rights & permissionsfor article Intestinal metaplasia of the urinary tract harbors potentially oncogenic genetic variants . Opens in a new window.
Research | 22 October 2019
Metaplastic thymoma: a distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions
Modern Pathology 33 , 560–565

Rights & permissionsfor article Metaplastic thymoma: a distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions . Opens in a new window.
Research | 5 August 2020
Mural nodules in mucinous ovarian tumors represent a morphologic spectrum of clonal neoplasms: a morphologic, immunohistochemical, and molecular analysis of 13 cases
Modern Pathology , 1–14

Rights & permissionsfor article Mural nodules in mucinous ovarian tumors represent a morphologic spectrum of clonal neoplasms: a morphologic, immunohistochemical, and molecular analysis of 13 cases . Opens in a new window.
Research | 13 August 2019
Quantitative assessment of PD-L1 as an analyte in immunohistochemistry diagnostic assays using a standardized cell line tissue microarray
- Sandra Martinez-Morilla
- , John McGuire
- , Patricia Gaule
- , Lauren Moore
- , Balazs Acs
- , Delphine Cougot
- , Allen M. Gown
- , Hadi Yaziji
- , Wei-Lien Wang
- , Richard W. Cartun
- , Jason L. Hornick
- , Lynette M. Sholl
- , Jingxin Qiu
- , Mari Mino-Kenudson
- , Eunhee S. Yi
- , Mary Beth Beasley
- , Daniel T. Merrick
- , Abiy B. Ambaye
- , Zhong J. Zhang
- , Jill Walker
- & David L. Rimm
Laboratory Investigation 100 , 4–15

Rights & permissionsfor article Quantitative assessment of PD-L1 as an analyte in immunohistochemistry diagnostic assays using a standardized cell line tissue microarray . Opens in a new window.
Research | 22 June 2020
ARID1A mutations and expression loss in non-small cell lung carcinomas: clinicopathologic and molecular analysis
Modern Pathology 33 , 2256–2268

Rights & permissionsfor article ARID1A mutations and expression loss in non-small cell lung carcinomas: clinicopathologic and molecular analysis . Opens in a new window.
Research | 28 June 2018
Validation of a targeted next-generation sequencing approach to detect mismatch repair deficiency in colorectal adenocarcinoma
Modern Pathology 31 , 1882–1890

Rights & permissionsfor article Validation of a targeted next-generation sequencing approach to detect mismatch repair deficiency in colorectal adenocarcinoma . Opens in a new window.
Research | 4 August 2017
GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas
Modern Pathology 30 , 1720–1727

Rights & permissionsfor article GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas . Opens in a new window.
26 January 2017
Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study
- Arezou A. Ghazani
- , Nelly M. Oliver
- , Joseph P. St. Pierre
- , Andrea Garofalo
- , Irene R. Rainville
- , Elaine Hiller
- , Daniel J. Treacy
- , Vanesa Rojas-Rudilla
- , Sam Wood
- , Elizabeth Bair
- , Michael Parello
- , Franklin Huang
- , Marios Giannakis
- , Frederick H. Wilson
- , Elizabeth H. Stover
- , Steven M. Corsello
- , Tom Nguyen
- , Huma Q. Rana
- , Alanna J. Church
- , Carol Lowenstein
- , Carrie Cibulskis
- , Ali Amin-Mansour
- , Jennifer Heng
- , Lauren Brais
- , Abigail Santos
- , Patrick Bauer
- , Amanda Waldron
- , Peter Lo
- , Megan Gorman
- , Christine A. Lydon
- , Marisa Welch
- , Philip McNamara
- , Stacey Gabriel
- , Lynette M. Sholl
- , Neal I. Lindeman
- , Judy E. Garber
- , Steven Joffe
- , Eliezer M. Van Allen
- , Stacy W. Gray
- , Pasi A. Jänne
- , Levi A. Garraway
- & Nikhil Wagle
Genetics in Medicine 19 , 787–795

Rights & permissionsfor article Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study . Opens in a new window.
Research | 13 January 2017
Recurrent IDH2 R172X mutations in sinonasal undifferentiated carcinoma
Modern Pathology 30 , 650–659

Rights & permissionsfor article Recurrent IDH2 R172X mutations in sinonasal undifferentiated carcinoma . Opens in a new window.
Research | 6 May 2016
Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas
Modern Pathology 29 , 893–903

Rights & permissionsfor article Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas . Opens in a new window.
Research | 23 January 2015
Expression of ROS1 predicts ROS1 gene rearrangement in inflammatory myofibroblastic tumors
Modern Pathology 28 , 732–739

Rights & permissionsfor article Expression of ROS1 predicts ROS1 gene rearrangement in inflammatory myofibroblastic tumors . Opens in a new window.
Research | 13 November 2015
Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-κB regulatory genes
Modern Pathology 29 , 67–74

Rights & permissionsfor article Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-κB regulatory genes . Opens in a new window.
Research | 4 September 2015
Targeted genomic profiling reveals recurrent KRAS mutations and gain of chromosome 1q in mesonephric carcinomas of the female genital tract
- Jelena Mirkovic
- , Lynette M Sholl
- , Elizabeth Garcia
- , Neal Lindeman
- , Laura MacConaill
- , Michelle Hirsch
- , Paola Dal Cin
- , Melissa Gorman
- , Justine A Barletta
- , Marisa R Nucci
- , W Glenn McCluggage
- & Brooke E Howitt
Modern Pathology 28 , 1504–1514

Rights & permissionsfor article Targeted genomic profiling reveals recurrent KRAS mutations and gain of chromosome 1q in mesonephric carcinomas of the female genital tract . Opens in a new window.
Research | 18 January 2009
In situ genetic analysis of cellular chimerism
- David Wu
- , Quynh Vu
- , Anhthu Nguyen
- , James R Stone
- , Hannah Stubbs
- , Georgiana Kuhlmann
- , Lynette M Sholl
- & A John Iafrate
Nature Medicine 15 , 215–219

Rights & permissionsfor article In situ genetic analysis of cellular chimerism . Opens in a new window.
Research | 3 August 2007
Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma
- Lynette M Sholl
- , A John Iafrate
- , Yi-Ping Chou
- , Ming-Tsang Wu
- , Yih-Gang Goan
- , Li Su
- , Yen-Tsung Huang
- , David C Christiani
- & Lucian R Chirieac
Modern Pathology 20 , 1028–1035

Rights & permissionsfor article Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma . Opens in a new window.
Research | 9 January 2019
Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma
Modern Pathology 32 , 830–843

Rights & permissionsfor article Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma . Opens in a new window.
Research | 14 February 2019
Characteristics of mismatch repair deficiency in sarcomas
Modern Pathology 32 , 977–987

Rights & permissionsfor article Characteristics of mismatch repair deficiency in sarcomas . Opens in a new window.
Research | 27 August 2018
Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors
- Diana Miao
- , Claire A. Margolis
- , Natalie I. Vokes
- , David Liu
- , Amaro Taylor-Weiner
- , Stephanie M. Wankowicz
- , Dennis Adeegbe
- , Daniel Keliher
- , Bastian Schilling
- , Adam Tracy
- , Michael Manos
- , Nicole G. Chau
- , Glenn J. Hanna
- , Paz Polak
- , Scott J. Rodig
- , Sabina Signoretti
- , Lynette M. Sholl
- , Jeffrey A. Engelman
- , Gad Getz
- , Pasi A. Jänne
- , Robert I. Haddad
- , Toni K. Choueiri
- , David A. Barbie
- , Rizwan Haq
- , Mark M. Awad
- , Dirk Schadendorf
- , F. Stephen Hodi
- , Joaquim Bellmunt
- , Kwok-Kin Wong
- , Peter Hammerman
- & Eliezer M. Van Allen
Nature Genetics 50 , 1271–1281

Rights & permissionsfor article Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors . Opens in a new window.
Reviews | 1 December 2017
Implications of the tumor immune microenvironment for staging and therapeutics
- Janis M Taube
- , Jérôme Galon
- , Lynette M Sholl
- , Scott J Rodig
- , Tricia R Cottrell
- , Nicolas A Giraldo
- , Alexander S Baras
- , Sanjay S Patel
- , Robert A Anders
- , David L Rimm
- & Ashley Cimino-Mathews
Modern Pathology 31 , 214–234

Rights & permissionsfor article Implications of the tumor immune microenvironment for staging and therapeutics . Opens in a new window.
Research | 7 April 2017 | Open
Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2
- Haikuo Zhang
- , Christine Fillmore Brainson
- , Shohei Koyama
- , Amanda J. Redig
- , Ting Chen
- , Shuai Li
- , Manav Gupta
- , Carolina Garcia-de-Alba
- , Margherita Paschini
- , Grit S. Herter-Sprie
- , Gang Lu
- , Xin Zhang
- , Bryan P. Marsh
- , Stephanie J. Tuminello
- , Chunxiao Xu
- , Zhao Chen
- , Xiaoen Wang
- , Esra A. Akbay
- , Mei Zheng
- , Sangeetha Palakurthi
- , Lynette M. Sholl
- , Anil K. Rustgi
- , David J. Kwiatkowski
- , J Alan Diehl
- , Adam J. Bass
- , Norman E. Sharpless
- , Glenn Dranoff
- , Peter S. Hammerman
- , Hongbin Ji
- , Nabeel Bardeesy
- , Dieter Saur
- , Hideo Watanabe
- , Carla F. Kim
- & Kwok-Kin Wong
Nature Communications 8 , 1–15

Rights & permissionsfor article Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2 . Opens in a new window.
Research | 1 February 2016
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma
- Yotam Drier
- , Matthew J Cotton
- , Kaylyn E Williamson
- , Shawn M Gillespie
- , Russell J H Ryan
- , Michael J Kluk
- , Christopher D Carey
- , Scott J Rodig
- , Lynette M Sholl
- , Amir H Afrogheh
- , William C Faquin
- , Lurdes Queimado
- , Jun Qi
- , Michael J Wick
- , Adel K El-Naggar
- , James E Bradner
- , Christopher A Moskaluk
- , Jon C Aster
- , Birgit Knoechel
- & Bradley E Bernstein
Nature Genetics 48 , 265–272

Rights & permissionsfor article An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma . Opens in a new window.
Research | 18 July 2014
Succinate dehydrogenase-deficient renal cell carcinoma: detailed characterization of 11 tumors defining a unique subtype of renal cell carcinoma
- Sean R Williamson
- , John N Eble
- , Mahul B Amin
- , Nilesh S Gupta
- , Steven C Smith
- , Lynette M Sholl
- , Rodolfo Montironi
- , Michelle S Hirsch
- & Jason L Hornick
Modern Pathology 28 , 80–94

Rights & permissionsfor article Succinate dehydrogenase-deficient renal cell carcinoma: detailed characterization of 11 tumors defining a unique subtype of renal cell carcinoma . Opens in a new window.

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Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection

In situ detection of SARS-CoV-2 in lungs and airways of patients with COVID-19

Erratum: Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

Strategies for the successful implementation of plasma-based NSCLC genotyping in clinical practice

Intestinal metaplasia of the urinary tract harbors potentially oncogenic genetic variants

Metaplastic thymoma: a distinctive thymic neoplasm characterized by YAP1-MAML2 gene fusions

Mural nodules in mucinous ovarian tumors represent a morphologic spectrum of clonal neoplasms: a morphologic, immunohistochemical, and molecular analysis of 13 cases

Quantitative assessment of PD-L1 as an analyte in immunohistochemistry diagnostic assays using a standardized cell line tissue microarray

ARID1A mutations and expression loss in non-small cell lung carcinomas: clinicopathologic and molecular analysis

Validation of a targeted next-generation sequencing approach to detect mismatch repair deficiency in colorectal adenocarcinoma

GNAS mutations in primary mucinous and non-mucinous lung adenocarcinomas

Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study

Recurrent IDH2 R172X mutations in sinonasal undifferentiated carcinoma

Morphologic correlates of molecular alterations in extrauterine Müllerian carcinomas

Expression of ROS1 predicts ROS1 gene rearrangement in inflammatory myofibroblastic tumors

Targeted genomic sequencing of follicular dendritic cell sarcoma reveals recurrent alterations in NF-κB regulatory genes

Targeted genomic profiling reveals recurrent KRAS mutations and gain of chromosome 1q in mesonephric carcinomas of the female genital tract

In situ genetic analysis of cellular chimerism

Validation of chromogenic in situ hybridization for detection of EGFR copy number amplification in nonsmall cell lung carcinoma

Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma

Characteristics of mismatch repair deficiency in sarcomas

Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors

Implications of the tumor immune microenvironment for staging and therapeutics

Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma

Succinate dehydrogenase-deficient renal cell carcinoma: detailed characterization of 11 tumors defining a unique subtype of renal cell carcinoma

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