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Research | 13 January 2021 | Open
Development of an immune-related gene pairs index for the prognosis analysis of metastatic melanoma
- Rong-zhi Huang
- , Min Mao
- , Jie Zheng
- , Hai-qi Liang
- , Feng-ling Liu
- , Gui-you Zhou
- , Yao-qing Huang
- , Fan-yue Zeng
- & Xu Li
Scientific Reports 11 , 1–12

Rights & permissionsfor article Development of an immune-related gene pairs index for the prognosis analysis of metastatic melanoma . Opens in a new window.
Research | 10 September 2020 | Open
Accuracy assessment of a novel semiautomatic method evaluating bone grafts around the dental implant: an in vitro and ex vivo study
- Jun-Yu Shi
- , Yuan Li
- , Long-Fei Zhuang
- , Xiao Zhang
- , Ling-Feng Fan
- & Hong-Chang Lai
Scientific Reports 10 , 1–8

Rights & permissionsfor article Accuracy assessment of a novel semiautomatic method evaluating bone grafts around the dental implant: an in vitro and ex vivo study . Opens in a new window.
Amendments and Corrections | 17 June 2019 | Open
Publisher Correction: Extreme risk induced by communities in interdependent networks
- Jiachen Sun
- , Rui Zhang
- , Ling Feng
- , Christopher Monterola
- , Xiao Ma
- , Céline Rozenblat
- , H. Eugene Stanley
- , Boris Podobnik
- & Yanqing Hu
Communications Physics 2 , 1–1

Rights & permissionsfor article Publisher Correction: Extreme risk induced by communities in interdependent networks . Opens in a new window.
Research | 5 February 2019 | Open
Extracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-κB signaling
- Ling-feng Wan
- , Jian-jiang Shen
- , Yao-hui Wang
- , Wei Zhao
- , Nan-yuan Fang
- , Xin Yuan
- & Bo-yu Xue
Scientific Reports 9 , 1–13

Rights & permissionsfor article Extracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-κB signaling . Opens in a new window.
Research | 18 April 2018 | Open
IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population
- Ling-Feng Zha
- , Shao-Fang Nie
- , Qian-Wen Chen
- , Yu-Hua Liao
- , Hong-Song Zhang
- , Jiang-Tao Dong
- , Tian Xie
- , Fan Wang
- , Ting-Ting Tang
- , Ni Xia
- , Cheng-Qi Xu
- , Ying-Chao Zhou
- , Zhi-Peng Zeng
- , Jiao Jiao
- , Peng-Yun Wang
- , Qing K. Wang
- , Xin Tu
- & Xiang Cheng
Scientific Reports 8 , 1–8

Rights & permissionsfor article IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population . Opens in a new window.
Research | 31 May 2017 | Open
Sex-specific responses to winter flooding, spring waterlogging and post-flooding recovery in Populus deltoides
- Ling-Feng Miao
- , Fan Yang
- , Chun-Yu Han
- , Yu-Jin Pu
- , Yang Ding
- & Li-Jia Zhang
Scientific Reports 7 , 1–14

Rights & permissionsfor article Sex-specific responses to winter flooding, spring waterlogging and post-flooding recovery in Populus deltoides . Opens in a new window.
Research | 31 January 2018
Evolutionary history of the angiosperm flora of China
- Li-Min Lu
- , Ling-Feng Mao
- , Tuo Yang
- , Jian-Fei Ye
- , Bing Liu
- , Hong-Lei Li
- , Miao Sun
- , Joseph T. Miller
- , Sarah Mathews
- , Hai-Hua Hu
- , Yan-Ting Niu
- , Dan-Xiao Peng
- , You-Hua Chen
- , Stephen A. Smith
- , Min Chen
- , Kun-Li Xiang
- , Chi-Toan Le
- , Viet-Cuong Dang
- , An-Ming Lu
- , Pamela S. Soltis
- , Douglas E. Soltis
- , Jian-Hua Li
- & Zhi-Duan Chen
Nature 554 , 234–238

Rights & permissionsfor article Evolutionary history of the angiosperm flora of China . Opens in a new window.
Research | 31 August 2016 | Open
Chronic Rhinosinusitis Associated with Erectile Dysfunction: A Population-Based Study
- Shu-Yu Tai
- , Ling-Feng Wang
- , Chih-Feng Tai
- , Yu-Ting Huang
- & Chen-Yu Chien
Scientific Reports 6 , 1–7

Rights & permissionsfor article Chronic Rhinosinusitis Associated with Erectile Dysfunction: A Population-Based Study . Opens in a new window.
Research | 17 December 2015 | Open
Physical Modeling of Gate-Controlled Schottky Barrier Lowering of Metal-Graphene Contacts in Top-Gated Graphene Field-Effect Transistors
Scientific Reports 5 , 1–11

Rights & permissionsfor article Physical Modeling of Gate-Controlled Schottky Barrier Lowering of Metal-Graphene Contacts in Top-Gated Graphene Field-Effect Transistors . Opens in a new window.
Research | 6 October 2016 | Open
Epitomics: IgG-epitome decoding of E6, E7 and L1 proteins from oncogenic human papillomavirus type 58
- Wan-Xiang Xu
- , Jian Wang
- , Hai-Ping Tang
- , Ya-Ping He
- , Qian-Xi Zhu
- , Satish K. Gupta
- , Shao-Hua Gu
- , Qiang Huang
- , Chao-Neng Ji
- , Ling-Feng Liu
- , Gui-Ling Li
- , Cong-Jian Xu
- & Yi Xie
Scientific Reports 6 , 1–14

Rights & permissionsfor article Epitomics: IgG-epitome decoding of E6, E7 and L1 proteins from oncogenic human papillomavirus type 58 . Opens in a new window.
Research | 22 April 2016 | Open
Physical Modeling of Activation Energy in Organic Semiconductor Devices based on Energy and Momentum Conservations
- Ling-Feng Mao
- , H. Ning
- , Changjun Hu
- , Zhaolin Lu
- & Gaofeng Wang
Scientific Reports 6 , 1–12

Rights & permissionsfor article Physical Modeling of Activation Energy in Organic Semiconductor Devices based on Energy and Momentum Conservations . Opens in a new window.
Research | 24 April 2003 | Open
Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
- Shuang-Xi Ren
- , Gang Fu
- , Xiu-Gao Jiang
- , Rong Zeng
- , You-Gang Miao
- , Hai Xu
- , Yi-Xuan Zhang
- , Hui Xiong
- , Gang Lu
- , Ling-Feng Lu
- , Hong-Quan Jiang
- , Jia Jia
- , Yue-Feng Tu
- , Ju-Xing Jiang
- , Wen-Yi Gu
- , Yue-Qing Zhang
- , Zhen Cai
- , Hai-Hui Sheng
- , Hai-Feng Yin
- , Yi Zhang
- , Gen-Feng Zhu
- , Ma Wan
- , Hong-Lei Huang
- , Zhen Qian
- , Sheng-Yue Wang
- , Wei Ma
- , Zhi-Jian Yao
- , Yan Shen
- , Bo-Qin Qiang
- , Qi-Chang Xia
- , Xiao-Kui Guo
- , Antoine Danchin
- , Isabelle Saint Girons
- , Ronald L. Somerville
- , Yu-Mei Wen
- , Man-Hua Shi
- , Zhu Chen
- , Jian-Guo Xu
- & Guo-Ping Zhao
Nature 422 , 888–893

Rights & permissionsfor article Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing . Opens in a new window.
Research | 3 September 2018 | Open
Mechanistic modelling of viral spreading on empirical social network and popularity prediction
- Sijuan Ma
- , Ling Feng
- & Choy-Heng Lai
Scientific Reports 8 , 1–10

Rights & permissionsfor article Mechanistic modelling of viral spreading on empirical social network and popularity prediction . Opens in a new window.
Research | 28 August 2018 | Open
Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay
- Xian Zhao
- , Hai-Yong Tu
- , Lei Guo
- , Shengqing Zhu
- , Feng-Ling Qing
- & Lingling Chu
Nature Communications 9 , 1–7

Rights & permissionsfor article Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay . Opens in a new window.
Research | 28 September 2018 | Open
A study of the correlation between obesity and intestinal flora in school-age children
- Xiaolin Gao
- , Ruizhen Jia
- , Liang Xie
- , Linghan Kuang
- , Ling Feng
- & Chaomin Wan
Scientific Reports 8 , 1–8

Rights & permissionsfor article A study of the correlation between obesity and intestinal flora in school-age children . Opens in a new window.
Research | 19 October 2017
Hematopoietic stem cell-derived exosomes promote hematopoietic differentiation of mouse embryonic stem cells in vitro via inhibiting the miR126/Notch1 pathway
- Feng-ling Liao
- , Lin Tan
- , Hua Liu
- , Jin-ju Wang
- , Xiao-tang Ma
- , Bin Zhao
- , Yanfang Chen
- , Ji Bihl
- , Yi Yang
- & Ri-ling Chen
Acta Pharmacologica Sinica 39 , 552–560

Rights & permissionsfor article Hematopoietic stem cell-derived exosomes promote hematopoietic differentiation of mouse embryonic stem cells in vitro via inhibiting the miR126/Notch1 pathway . Opens in a new window.
Research | 8 September 2016 | Open
Factors associated with Severe Fever with Thrombocytopenia Syndrome infection and fatal outcome
- Jimin Sun
- , Zhenyu Gong
- , Feng Ling
- , Rong Zhang
- , Zhendong Tong
- , Yue Chang
- , Enfu Chen
- , Qiyong Liu
- , Junfen Lin
- , Zhiping Chen
- & Jianmin Jiang
Scientific Reports 6 , 1–6

Rights & permissionsfor article Factors associated with Severe Fever with Thrombocytopenia Syndrome infection and fatal outcome . Opens in a new window.
Research | 3 March 2017 | Open
Risk factors for avian influenza virus contamination of live poultry markets in Zhejiang, China during the 2015–2016 human influenza season
- Xiaoxiao Wang
- , Qimei Wang
- , Wei Cheng
- , Zhao Yu
- , Feng Ling
- , Haiyan Mao
- & Enfu Chen
Scientific Reports 7 , 1–9

Rights & permissionsfor article Risk factors for avian influenza virus contamination of live poultry markets in Zhejiang, China during the 2015–2016 human influenza season . Opens in a new window.
Research | 29 January 2020 | Open
Revealing the predictability of intrinsic structure in complex networks
- Jiachen Sun
- , Ling Feng
- , Jiarong Xie
- , Xiao Ma
- , Dashun Wang
- & Yanqing Hu
Nature Communications 11 , 1–10

Rights & permissionsfor article Revealing the predictability of intrinsic structure in complex networks . Opens in a new window.
Research | 22 November 2010
Sorafenib extends the survival time of patients with multiple recurrences of hepatocellular carcinoma after liver transplantation
- Wei-feng Tan
- , Zhi-quan Qiu
- , Yong Yu
- , Rong-zheng Ran
- , Bing Yi
- , Wan-yee Lau
- , Chen Liu
- , Ying-he Qiu
- , Fei-ling Feng
- , Jing-han Wang
- , Pei-ning Yan
- , Bai-he Zhang
- , Meng-chao Wu
- , Xiang-ji Luo
- & Xiao-qing Jiang
Acta Pharmacologica Sinica 31 , 1643–1648

Rights & permissionsfor article Sorafenib extends the survival time of patients with multiple recurrences of hepatocellular carcinoma after liver transplantation . Opens in a new window.
1 February 2011
Pneumococcal Peptidoglycan-Polysaccharides Regulate Toll-Like Receptor 2 in the Mouse Middle Ear Epithelial Cells
- Masahiro Komori
- , Yoshihisa Nakamura
- , Jesse Ping
- , Ling Feng
- , Katsuhiro Toyama
- , Youngki Kim
- , Patricia Ferrieri
- & Jizhen Lin
Pediatric Research 69 , 101–105

Rights & permissionsfor article Pneumococcal Peptidoglycan-Polysaccharides Regulate Toll-Like Receptor 2 in the Mouse Middle Ear Epithelial Cells . Opens in a new window.
1 December 2000
Identification and genetic mapping of four novel genes that regulate leaf development in Arabidopsis
- Yue SUN
- , Wei ZHANG
- , Feng Ling LI
- , Ying Li GUO
- , Tian Lei LIU
- & Hai HUANG
Cell Research 10 , 325–335

Rights & permissionsfor article Identification and genetic mapping of four novel genes that regulate leaf development in Arabidopsis . Opens in a new window.
Research | 26 November 2012 | Open
Changes in Cross-Correlations as an Indicator for Systemic Risk
- Zeyu Zheng
- , Boris Podobnik
- , Ling Feng
- & Baowen Li
Scientific Reports 2 , 1–8

Rights & permissionsfor article Changes in Cross-Correlations as an Indicator for Systemic Risk . Opens in a new window.
Research | 3 July 2009
Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells
- Peng-fei Ge
- , Ji-zhou Zhang
- , Xiao-fei Wang
- , Fan-kai Meng
- , Wen-chen Li
- , Yong-xin Luan
- , Feng Ling
- & Yi-nan Luo
Acta Pharmacologica Sinica 30 , 1046–1052

Rights & permissionsfor article Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells . Opens in a new window.
Research | 1 November 2007
Sodium butyrate-induced death-associated protein kinase expression promote Raji cell morphological change and apoptosis by reducing FAK protein levels
- Hai-tao Zhang
- , Zhe-ling Feng
- , Jun Wu
- , Ya-jun Wang
- , Xia Guo
- , Nian-ci Liang
- , Zhen-yu Zhu
- & Jian-quan Ma
Acta Pharmacologica Sinica 28 , 1783–1790

Rights & permissionsfor article Sodium butyrate-induced death-associated protein kinase expression promote Raji cell morphological change and apoptosis by reducing FAK protein levels . Opens in a new window.
Research | 27 December 2019 | Open
Expression response of chalcone synthase gene to inducing conditions and its effect on flavonoids accumulation in two medicinal species of Anoectochilus
- Lin Yang
- , Jun Cheng Zhang
- , Jing Tao Qu
- , Gang He
- , Hao Qiang Yu
- , Wan Chen Li
- & Feng Ling Fu
Scientific Reports 9 , 1–10

Rights & permissionsfor article Expression response of chalcone synthase gene to inducing conditions and its effect on flavonoids accumulation in two medicinal species of Anoectochilus . Opens in a new window.
Research | 8 May 2019 | Open
Extreme risk induced by communities in interdependent networks
- Jiachen Sun
- , Rui Zhang
- , Ling Feng
- , Christopher Monterola
- , Xiao Ma
- , Céline Rozenblat
- , H. Eugene Stanley
- , Boris Podobnik
- & Yanqing Hu
Communications Physics 2 , 1–7

Rights & permissionsfor article Extreme risk induced by communities in interdependent networks . Opens in a new window.
Research | 1 April 2019 | Open
Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr1
Scientific Reports 9 , 1–12

Rights & permissionsfor article Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr1 . Opens in a new window.
Research | 18 December 2018 | Open
Ergosterol peroxide from marine fungus Phoma sp. induces ROS-dependent apoptosis and autophagy in human lung adenocarcinoma cells
- Han-Ying Wu
- , Feng-Ling Yang
- , Lan-Hui Li
- , Yerra Koteswara Rao
- , Tz-Chuen Ju
- , Wei-Ting Wong
- , Chih-Yu Hsieh
- , Michael V. Pivkin
- , Kuo-Feng Hua
- & Shih-Hsiung Wu
Scientific Reports 8 , 1–14

Rights & permissionsfor article Ergosterol peroxide from marine fungus Phoma sp. induces ROS-dependent apoptosis and autophagy in human lung adenocarcinoma cells . Opens in a new window.
Research | 9 March 2018 | Open
Evaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization
- Ji Yan
- , Shu Zhang
- , Dejia Huang
- , Xiaolin Xue
- , Jing Xu
- , Qianmin Tao
- , Weize Zhang
- , Zheng Zhang
- , Wei Hua
- , Yanchun Liang
- , Baopeng Tang
- , Wei Xu
- , Geng Xu
- , Xuejun Ren
- , Jingfeng Wang
- , Tao Guo
- , Shaobin Jia
- , Yugang Dong
- , Hong Jiang
- , Guosheng Fu
- , Liguang Zhu
- , Lin Chen
- , Fuli Tian
- , Feng Ling
- , Jianmei Li
- , Xiaoyong Qi
- , Yinglu Hao
- , Yutang Wang
- , Liangrong Zheng
- , Xiaoqun Pu
- , Farong Shen
- , Guangping Li
- , Hui Li
- & Fang Peng
Scientific Reports 8 , 1–10

Rights & permissionsfor article Evaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization . Opens in a new window.
Research | 17 February 2017 | Open
Structural basis for fragmenting the exopolysaccharide of Acinetobacter baumannii by bacteriophage ΦAB6 tailspike protein
- I-Ming Lee
- , I-Fan Tu
- , Feng-Ling Yang
- , Tzu-Ping Ko
- , Jiahn-Haur Liao
- , Nien-Tsung Lin
- , Chung-Yi Wu
- , Chien-Tai Ren
- , Andrew H.-J. Wang
- , Ching-Ming Chang
- , Kai-Fa Huang
- & Shih-Hsiung Wu
Scientific Reports 7 , 1–13

Rights & permissionsfor article Structural basis for fragmenting the exopolysaccharide of Acinetobacter baumannii by bacteriophage ΦAB6 tailspike protein . Opens in a new window.
Research | 23 August 2016 | Open
Identification of a capsular variant and characterization of capsular acetylation in Klebsiella pneumoniae PLA-associated type K57
- Chun-Ru Hsu
- , Chun-Hsing Liao
- , Tzu-Lung Lin
- , Han-Ru Yang
- , Feng-Ling Yang
- , Pei-Fang Hsieh
- , Shih-Hsiung Wu
- & Jin-Town Wang
Scientific Reports 6 , 1–13

Rights & permissionsfor article Identification of a capsular variant and characterization of capsular acetylation in Klebsiella pneumoniae PLA-associated type K57 . Opens in a new window.
Research | 14 January 2015 | Open
Distance-Dependent Plasmon-Enhanced Fluorescence of Upconversion Nanoparticles using Polyelectrolyte Multilayers as Tunable Spacers
- Ai Ling Feng
- , Min Li You
- , Limei Tian
- , Srikanth Singamaneni
- , Ming Liu
- , Zhenfeng Duan
- , Tian Jian Lu
- , Feng Xu
- & Min Lin
Scientific Reports 5 , 1–10

Rights & permissionsfor article Distance-Dependent Plasmon-Enhanced Fluorescence of Upconversion Nanoparticles using Polyelectrolyte Multilayers as Tunable Spacers . Opens in a new window.
Research | 11 July 2011
Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes
- Hong Zhou
- , Yong-jun Li
- , Mian Wang
- , Li-hui Zhang
- , Bing-yan Guo
- , Zhan-sheng Zhao
- , Feng-ling Meng
- , Yong-gui Deng
- & Rui-ying Wang
Acta Pharmacologica Sinica 32 , 999–1008

Rights & permissionsfor article Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes . Opens in a new window.
12 April 2010
Bisphenol A in combination with TNF-α selectively induces Th2 cell-promoting dendritic cells in vitro with an estrogen-like activity
- Hongchuan Guo
- , Tianyi Liu
- , Yasushi Uemura
- , Shunchang Jiao
- , Deqing Wang
- , Zilin Lin
- , Yayoi Narita
- , Motoharu Suzuki
- , Narumi Hirosawa
- , Yasuko Ichihara
- , Osamu Ishihara
- , Hirosato Kikuchi
- , Yasushi Sakamoto
- , Satoru Senju
- , Qiuhang Zhang
- & Feng Ling
Cellular & Molecular Immunology 7 , 227–234

Rights & permissionsfor article Bisphenol A in combination with TNF-α selectively induces Th2 cell-promoting dendritic cells in vitro with an estrogen-like activity . Opens in a new window.

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Development of an immune-related gene pairs index for the prognosis analysis of metastatic melanoma

Accuracy assessment of a novel semiautomatic method evaluating bone grafts around the dental implant: an in vitro and ex vivo study

Publisher Correction: Extreme risk induced by communities in interdependent networks

Extracts of Qizhu decoction inhibit hepatitis and hepatocellular carcinoma in vitro and in C57BL/6 mice by suppressing NF-κB signaling

IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population

Sex-specific responses to winter flooding, spring waterlogging and post-flooding recovery in Populus deltoides

Evolutionary history of the angiosperm flora of China

Chronic Rhinosinusitis Associated with Erectile Dysfunction: A Population-Based Study

Physical Modeling of Gate-Controlled Schottky Barrier Lowering of Metal-Graphene Contacts in Top-Gated Graphene Field-Effect Transistors

Epitomics: IgG-epitome decoding of E6, E7 and L1 proteins from oncogenic human papillomavirus type 58

Physical Modeling of Activation Energy in Organic Semiconductor Devices based on Energy and Momentum Conservations

Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing

Mechanistic modelling of viral spreading on empirical social network and popularity prediction

Intermolecular selective carboacylation of alkenes via nickel-catalyzed reductive radical relay

A study of the correlation between obesity and intestinal flora in school-age children

Hematopoietic stem cell-derived exosomes promote hematopoietic differentiation of mouse embryonic stem cells in vitro via inhibiting the miR126/Notch1 pathway

Factors associated with Severe Fever with Thrombocytopenia Syndrome infection and fatal outcome

Risk factors for avian influenza virus contamination of live poultry markets in Zhejiang, China during the 2015–2016 human influenza season

Revealing the predictability of intrinsic structure in complex networks

Sorafenib extends the survival time of patients with multiple recurrences of hepatocellular carcinoma after liver transplantation

Pneumococcal Peptidoglycan-Polysaccharides Regulate Toll-Like Receptor 2 in the Mouse Middle Ear Epithelial Cells

Identification and genetic mapping of four novel genes that regulate leaf development in Arabidopsis

Changes in Cross-Correlations as an Indicator for Systemic Risk

Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells

Sodium butyrate-induced death-associated protein kinase expression promote Raji cell morphological change and apoptosis by reducing FAK protein levels

Expression response of chalcone synthase gene to inducing conditions and its effect on flavonoids accumulation in two medicinal species of Anoectochilus

Extreme risk induced by communities in interdependent networks

Prevention of mitochondrial genomic instability in yeast by the mitochondrial recombinase Mhr1

Ergosterol peroxide from marine fungus Phoma sp. induces ROS-dependent apoptosis and autophagy in human lung adenocarcinoma cells

Evaluation of the therapeutic effects of QuickOpt optimization in Chinese patients with chronic heart failure treated by cardiac resynchronization

Structural basis for fragmenting the exopolysaccharide of Acinetobacter baumannii by bacteriophage ΦAB6 tailspike protein

Identification of a capsular variant and characterization of capsular acetylation in Klebsiella pneumoniae PLA-associated type K57

Distance-Dependent Plasmon-Enhanced Fluorescence of Upconversion Nanoparticles using Polyelectrolyte Multilayers as Tunable Spacers

Involvement of RhoA/ROCK in myocardial fibrosis in a rat model of type 2 diabetes

Bisphenol A in combination with TNF-α selectively induces Th2 cell-promoting dendritic cells in vitro with an estrogen-like activity

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