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Amendments and Corrections | 29 August 2018
Publisher Correction: Suppression of insulin feedback enhances the efficacy of PI3K inhibitors
- Benjamin D. Hopkins
- , Chantal Pauli
- , Xing Du
- , Diana G. Wang
- , Xiang Li
- , David Wu
- , Solomon C. Amadiume
- , Marcus D. Goncalves
- , Cindy Hodakoski
- , Mark R. Lundquist
- , Rohan Bareja
- , Yan Ma
- , Emily M. Harris
- , Andrea Sboner
- , Himisha Beltran
- , Mark A. Rubin
- , Siddhartha Mukherjee
- & Lewis C. Cantley
Nature 563 , E24–E24

Rights & permissionsfor article Publisher Correction: Suppression of insulin feedback enhances the efficacy of PI3K inhibitors . Opens in a new window.
Amendments and Corrections | 3 September 2020
Author Correction: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer
- Andrea Lunardi
- , Ugo Ala
- , Mirjam T. Epping
- , Leonardo Salmena
- , John G. Clohessy
- , Kaitlyn A. Webster
- , Guocan Wang
- , Roberta Mazzucchelli
- , Maristella Bianconi
- , Edward C. Stack
- , Rosina Lis
- , Akash Patnaik
- , Lewis C. Cantley
- , Glenn Bubley
- , Carlos Cordon-Cardo
- , William L. Gerald
- , Rodolfo Montironi
- , Sabina Signoretti
- , Massimo Loda
- , Caterina Nardella
- & Pier Paolo Pandolfi
Nature Genetics 52 , 1132–1132

Rights & permissionsfor article Author Correction: A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer . Opens in a new window.
Amendments and Corrections | 29 March 2016
Erratum: NRF2 regulates serine biosynthesis in non–small cell lung cancer
- Gina M DeNicola
- , Pei-Hsuan Chen
- , Edouard Mullarky
- , Jessica A Sudderth
- , Zeping Hu
- , David Wu
- , Hao Tang
- , Yang Xie
- , John M Asara
- , Kenneth E Huffman
- , Ignacio I Wistuba
- , John D Minna
- , Ralph J DeBerardinis
- & Lewis C Cantley
Nature Genetics 48 , 473–473

Rights & permissionsfor article Erratum: NRF2 regulates serine biosynthesis in non–small cell lung cancer . Opens in a new window.
Amendments and Corrections | 5 October 2016
Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
- Cristovão M. Sousa
- , Douglas E. Biancur
- , Xiaoxu Wang
- , Christopher J. Halbrook
- , Mara H. Sherman
- , Li Zhang
- , Daniel Kremer
- , Rosa F. Hwang
- , Agnes K. Witkiewicz
- , Haoqiang Ying
- , John M. Asara
- , Ronald M. Evans
- , Lewis C. Cantley
- , Costas A. Lyssiotis
- & Alec C. Kimmelman
Nature 540 , 150–150

Rights & permissionsfor article Erratum: Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion . Opens in a new window.
Amendments and Corrections | 24 December 2012
Erratum: ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect
- Weiwei Yang
- , Yanhua Zheng
- , Yan Xia
- , Haitao Ji
- , Xiaomin Chen
- , Fang Guo
- , Costas A. Lyssiotis
- , Kenneth Aldape
- , Lewis C. Cantley
- & Zhimin Lu
Nature Cell Biology 15 , 124–124

Rights & permissionsfor article Erratum: ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect . Opens in a new window.
News and Views | 15 July 2020
A ‘fast’er way to treat breast cancer
- Marcus D. Goncalves
- & Lewis C. Cantley
Nature Metabolism 2 , 559–560

Rights & permissionsfor article A ‘fast’er way to treat breast cancer . Opens in a new window.
Research | 28 October 2020
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
- Yuling Han
- , Xiaohua Duan
- , Liuliu Yang
- , Benjamin E. Nilsson-Payant
- , Pengfei Wang
- , Fuyu Duan
- , Xuming Tang
- , Tomer M. Yaron
- , Tuo Zhang
- , Skyler Uhl
- , Yaron Bram
- , Chanel Richardson
- , Jiajun Zhu
- , Zeping Zhao
- , David Redmond
- , Sean Houghton
- , Duc-Huy T. Nguyen
- , Dong Xu
- , Xing Wang
- , Jose Jessurun
- , Alain Borczuk
- , Yaoxing Huang
- , Jared L. Johnson
- , Yuru Liu
- , Jenny Xiang
- , Hui Wang
- , Lewis C. Cantley
- , Benjamin R. tenOever
- , David D. Ho
- , Fong Cheng Pan
- , Todd Evans
- , Huanhuan Joyce Chen
- , Robert E. Schwartz
- & Shuibing Chen
Nature 589 , 270–275

Rights & permissionsfor article Identification of SARS-CoV-2 inhibitors using lung and colonic organoids . Opens in a new window.
Research | 30 October 2020 | Open
Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer
Nature Communications 11 , 1–15

Rights & permissionsfor article <i>Proline rich 11</i> (<i>PRR11</i>) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer . Opens in a new window.
News and Views | 4 November 1999
Grabbing phosphoproteins
- Michael B. Yaffe
- & Lewis C. Cantley
Nature 402 , 30–31

Rights & permissionsfor article Grabbing phosphoproteins . Opens in a new window.
Research | 19 August 2020
Age-induced accumulation of methylmalonic acid promotes tumour progression
- Ana P. Gomes
- , Didem Ilter
- , Vivien Low
- , Jennifer E. Endress
- , Juan Fernández-García
- , Adam Rosenzweig
- , Tanya Schild
- , Dorien Broekaert
- , Adnan Ahmed
- , Melanie Planque
- , Ilaria Elia
- , Julie Han
- , Charles Kinzig
- , Edouard Mullarky
- , Anders P. Mutvei
- , John Asara
- , Rafael de Cabo
- , Lewis C. Cantley
- , Noah Dephoure
- , Sarah-Maria Fendt
- & John Blenis
Nature 585 , 283–287

Rights & permissionsfor article Age-induced accumulation of methylmalonic acid promotes tumour progression . Opens in a new window.
Amendments and Corrections | 12 June 2013
Correction: Corrigendum: Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- Jaekyoung Son
- , Costas A. Lyssiotis
- , Haoqiang Ying
- , Xiaoxu Wang
- , Sujun Hua
- , Matteo Ligorio
- , Rushika M. Perera
- , Cristina R. Ferrone
- , Edouard Mullarky
- , Ng Shyh-Chang
- , Ya’an Kang
- , Jason B. Fleming
- , Nabeel Bardeesy
- , John M. Asara
- , Marcia C. Haigis
- , Ronald A. DePinho
- , Lewis C. Cantley
- & Alec C. Kimmelman
Nature 499 , 504–504

Rights & permissionsfor article Correction: Corrigendum: Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway . Opens in a new window.
News and Views | 9 October 2013
F stands for fructose and fat
- Costas A. Lyssiotis
- & Lewis C. Cantley
Nature 502 , 181–182

Rights & permissionsfor article F stands for fructose and fat . Opens in a new window.
Books and Arts | 1 October 2000
Phosphoinositide biology – messages from lipids
- Ji Luo
- & Lewis C. Cantley
Nature Cell Biology 2 , E190–E190

Rights & permissionsfor article Phosphoinositide biology – messages from lipids . Opens in a new window.
Research Highlights | 3 January 2012
Breathless cancer cells get fat on glutamine
- Dimitrios Anastasiou
- & Lewis C Cantley
Cell Research 22 , 443–446

Rights & permissionsfor article Breathless cancer cells get fat on glutamine . Opens in a new window.
News and Views | 1 October 1998
A flattened face for membranes
- Christopher L. Carpenter
- & Lewis C. Cantley
Nature Structural & Molecular Biology 5 , 843–845

Rights & permissionsfor article A flattened face for membranes . Opens in a new window.
News and Views | 1 October 2009
Cancer's insatiable appetite
Nature Biotechnology 27 , 916–917

Rights & permissionsfor article Cancer's insatiable appetite . Opens in a new window.
News and Views | 13 November 1997
A Bad kinase makes good
- Thomas F. Franke
- & Lewis C. Cantley
Nature 390 , 116–117

Rights & permissionsfor article A Bad kinase makes good . Opens in a new window.
Amendments and Corrections | 26 November 2012
Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
- Dimitrios Anastasiou
- , Yimin Yu
- , William J Israelsen
- , Jian-kang Jiang
- , Matthew B Boxer
- , Bum Soo Hong
- , Wolfram Tempel
- , Svetoslav Dimov
- , Min Shen
- , Abhishek Jha
- , Hua Yang
- , Katherine R Mattaini
- , Christian M Metallo
- , Brian P Fiske
- , Kevin D Courtney
- , Scott Malstrom
- , Tahsin M Khan
- , Charles Kung
- , Amanda P Skoumbourdis
- , Henrike Veith
- , Noel Southall
- , Martin J Walsh
- , Kyle R Brimacombe
- , William Leister
- , Sophia Y Lunt
- , Zachary R Johnson
- , Katharine E Yen
- , Kaiko Kunii
- , Shawn M Davidson
- , Heather R Christofk
- , Christopher P Austin
- , James Inglese
- , Marian H Harris
- , John M Asara
- , Gregory Stephanopoulos
- , Francesco G Salituro
- , Shengfang Jin
- , Lenny Dang
- , Douglas S Auld
- , Hee-Won Park
- , Lewis C Cantley
- , Craig J Thomas
- & Matthew G Vander Heiden
Nature Chemical Biology 8 , 1008–1008

Rights & permissionsfor article Erratum: Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis . Opens in a new window.
Research | 29 September 2004
A rapid method for determining protein kinase phosphorylation specificity
- Jessica E Hutti
- , Emily T Jarrell
- , James D Chang
- , Derek W Abbott
- , Peter Storz
- , Alex Toker
- , Lewis C Cantley
- & Benjamin E Turk
Nature Methods 1 , 27–29

Rights & permissionsfor article A rapid method for determining protein kinase phosphorylation specificity . Opens in a new window.
Amendments and Corrections | 17 June 2010
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
- Lenny Dang
- , David W. White
- , Stefan Gross
- , Bryson D. Bennett
- , Mark A. Bittinger
- , Edward M. Driggers
- , Valeria R. Fantin
- , Hyun Gyung Jang
- , Shengfang Jin
- , Marie C. Keenan
- , Kevin M. Marks
- , Robert M. Prins
- , Patrick S. Ward
- , Katharine E. Yen
- , Linda M. Liau
- , Joshua D. Rabinowitz
- , Lewis C. Cantley
- , Craig B. Thompson
- , Matthew G. Vander Heiden
- & Shinsan M. Su
Nature 465 , 966–966

Rights & permissionsfor article Cancer-associated IDH1 mutations produce 2-hydroxyglutarate . Opens in a new window.
Books and Arts | 8 September 2004
Sizing up a growing field
- Brendan D. Manning
- & Lewis C. Cantley
Nature 431 , 128–129

Rights & permissionsfor article Sizing up a growing field . Opens in a new window.
Research | 12 March 2019 | Open
Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase
- Yuxiang Zheng
- , Shivan Ramsamooj
- , Qian Li
- , Jared L. Johnson
- , Tomer M. Yaron
- , Klaus Sharra
- & Lewis C. Cantley
Scientific Reports 9 , 1–11

Rights & permissionsfor article Regulation of folate and methionine metabolism by multisite phosphorylation of human methylenetetrahydrofolate reductase . Opens in a new window.
Reviews | 3 March 2020
Insulin–PI3K signalling: an evolutionarily insulated metabolic driver of cancer
Nature Reviews Endocrinology 16 , 276–283

Rights & permissionsfor article Insulin–PI3K signalling: an evolutionarily insulated metabolic driver of cancer . Opens in a new window.
Research | 24 June 2002
A PtdInsP₃- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity
Nature Cell Biology 4 , 509–513

Rights & permissionsfor article A PtdInsP<sub>3</sub>- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity . Opens in a new window.
Research | 29 December 2003
Identification of small molecule inhibitors of anthrax lethal factor
- Rekha G Panchal
- , Ann R Hermone
- , Tam Luong Nguyen
- , Thiang Yian Wong
- , Robert Schwarzenbacher
- , James Schmidt
- , Douglas Lane
- , Connor McGrath
- , Benjamin E Turk
- , James Burnett
- , M Javad Aman
- , Stephen Little
- , Edward A Sausville
- , Daniel W Zaharevitz
- , Lewis C Cantley
- , Robert C Liddington
- , Rick Gussio
- & Sina Bavari
Nature Structural & Molecular Biology 11 , 67–72

Rights & permissionsfor article Identification of small molecule inhibitors of anthrax lethal factor . Opens in a new window.
Research | 1 April 2001
A motif-based profile scanning approach for genome-wide prediction of signaling pathways
Nature Biotechnology 19 , 348–353

Rights & permissionsfor article A motif-based profile scanning approach for genome-wide prediction of signaling pathways . Opens in a new window.
Research | 6 April 1978
Vanadate inhibits the red cell (Na⁺, K⁺) ATPase from the cytoplasmic side
Nature 272 , 552–554

Rights & permissionsfor article Vanadate inhibits the red cell (Na<sup>+</sup>, K<sup>+</sup>) ATPase from the cytoplasmic side . Opens in a new window.
Editorial | 12 December 2002
Overview of the Alliance for Cellular Signaling
- Alfred G. Gilman
- , Melvin I. Simon
- , Henry R. Bourne
- , Bruce A. Harris
- , Rochelle Long
- , Elliott M. Ross
- , James T. Stull
- , Ronald Taussig
- , Henry R. Bourne
- , Adam P. Arkin
- , Melanie H. Cobb
- , Jason G. Cyster
- , Peter N. Devreotes
- , James E. Ferrell
- , David Fruman
- , Michael Gold
- , Arthur Weiss
- , James T. Stull
- , Michael J. Berridge
- , Lewis C. Cantley
- , William A. Catterall
- , Shaun R. Coughlin
- , Eric N. Olson
- , Temple F. Smith
- , Joan S. Brugge
- , David Botstein
- , Jack E. Dixon
- , Tony Hunter
- , Robert J. Lefkowitz
- , Anthony J. Pawson
- , Paul W. Sternberg
- , Harold Varmus
- , Shankar Subramaniam
- , Robert S. Sinkovits
- , Joshua Li
- , Dennis Mock
- , Yuhong Ning
- , Brian Saunders
- , Paul C. Sternweis
- , Donald Hilgemann
- , Richard H. Scheuermann
- , Dianne DeCamp
- , Robert Hsueh
- , Keng-Mean Lin
- , Yan Ni
- , William E. Seaman
- , Paul C. Simpson
- , Timothy D. O'Connell
- , Tamara Roach
- , Melvin I. Simon
- , Sangdun Choi
- , Pamela Eversole-Cire
- , Iain Fraser
- , Marc C. Mumby
- , Yingming Zhao
- , Deirdre Brekken
- , Hongjun Shu
- , Tobias Meyer
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- , Won Do Heo
- , Jen Liou
- , Nancy O'Rourke
- , Mary Verghese
- , Susanne M. Mumby
- , Heping Han
- , H. Alex Brown
- , Jeffrey S. Forrester
- , Pavlina Ivanova
- , Stephen B. Milne
- , Patrick J. Casey
- , T. Kendall Harden
- , Adam P. Arkin
- , John Doyle
- , Martha L. Gray
- , Tobias Meyer
- , Stephen Michnick
- , Martin A. Schmidt
- , Mehmet Toner
- , Roger Y. Tsien
- , Madhusudan Natarajan
- , Rama Ranganathan
- & Gilberto R. Sambrano
Nature 420 , 703–706

Rights & permissionsfor article Overview of the Alliance for Cellular Signaling . Opens in a new window.
Research | 9 June 1994
SH2 domain specificity and activity modified by a single residue
Nature 369 , 502–505

Rights & permissionsfor article SH2 domain specificity and activity modified by a single residue . Opens in a new window.
Research | 1 November 2000
Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85α
Nature Genetics 26 , 379–382

Rights & permissionsfor article Hypoglycaemia, liver necrosis and perinatal death in mice lacking all isoforms of phosphoinositide 3-kinase p85α . Opens in a new window.
Research | 18 March 2012
A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response
- Zhao Chen
- , Katherine Cheng
- , Zandra Walton
- , Yuchuan Wang
- , Hiromichi Ebi
- , Takeshi Shimamura
- , Yan Liu
- , Tanya Tupper
- , Jing Ouyang
- , Jie Li
- , Peng Gao
- , Michele S. Woo
- , Chunxiao Xu
- , Masahiko Yanagita
- , Abigail Altabef
- , Shumei Wang
- , Charles Lee
- , Yuji Nakada
- , Christopher G. Peña
- , Yanping Sun
- , Yoko Franchetti
- , Catherine Yao
- , Amy Saur
- , Michael D. Cameron
- , Mizuki Nishino
- , D. Neil Hayes
- , Matthew D. Wilkerson
- , Patrick J. Roberts
- , Carrie B. Lee
- , Nabeel Bardeesy
- , Mohit Butaney
- , Lucian R. Chirieac
- , Daniel B. Costa
- , David Jackman
- , Norman E. Sharpless
- , Diego H. Castrillon
- , George D. Demetri
- , Pasi A. Jänne
- , Pier Paolo Pandolfi
- , Lewis C. Cantley
- , Andrew L. Kung
- , Jeffrey A. Engelman
- & Kwok-Kin Wong
Nature 483 , 613–617

Rights & permissionsfor article A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response . Opens in a new window.
Reviews | 12 June 1997
Signalling through the lipid products of phosphoinositide-3-OH kinase
- Alex Toker
- & Lewis C. Cantley
Nature 387 , 673–676

Rights & permissionsfor article Signalling through the lipid products of phosphoinositide-3-OH kinase . Opens in a new window.
Reviews | 28 February 2013
Cancer metabolism: fatty acid oxidation in the limelight
Nature Reviews Cancer 13 , 227–232

Rights & permissionsfor article Cancer metabolism: fatty acid oxidation in the limelight . Opens in a new window.
Research | 29 December 2003
The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor
Nature Structural & Molecular Biology 11 , 60–66

Rights & permissionsfor article The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor . Opens in a new window.
Research | 13 March 2008
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
Nature 452 , 230–233

Rights & permissionsfor article The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth . Opens in a new window.
Research | 13 November 1997
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate
Nature 390 , 192–196

Rights & permissionsfor article A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate . Opens in a new window.
Research | 9 February 1995
Catalytic specificity of protein-tyrosine kinases is critical for selective signalling
Nature 373 , 536–539

Rights & permissionsfor article Catalytic specificity of protein-tyrosine kinases is critical for selective signalling . Opens in a new window.
Protocols | 27 June 2006
Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates
Nature Protocols 1 , 375–379

Rights & permissionsfor article Determining protein kinase substrate specificity by parallel solution-phase assay of large numbers of peptide substrates . Opens in a new window.
Research | 30 November 2008
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
- Jeffrey A Engelman
- , Liang Chen
- , Xiaohong Tan
- , Katherine Crosby
- , Alexander R Guimaraes
- , Rabi Upadhyay
- , Michel Maira
- , Kate McNamara
- , Samanthi A Perera
- , Youngchul Song
- , Lucian R Chirieac
- , Ramneet Kaur
- , Angela Lightbown
- , Jessica Simendinger
- , Timothy Li
- , Robert F Padera
- , Carlos García-Echeverría
- , Ralph Weissleder
- , Umar Mahmood
- , Lewis C Cantley
- & Kwok-Kin Wong
Nature Medicine 14 , 1351–1356

Rights & permissionsfor article Effective use of PI3K and MEK inhibitors to treat mutant <i>Kras</i> G12D and <i>PIK3CA</i> H1047R murine lung cancers . Opens in a new window.
Research | 12 June 2001
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K
- Fumihiko Kanai
- , Hui Liu
- , Seth J. Field
- , Hares Akbary
- , Tsuyoshi Matsuo
- , Glenn E. Brown
- , Lewis C. Cantley
- & Michael B. Yaffe
Nature Cell Biology 3 , 675–678

Rights & permissionsfor article The PX domains of p47phox and p40phox bind to lipid products of PI(3)K . Opens in a new window.
Protocols | 27 June 2006
In-gel stable isotope labeling for relative quantification using mass spectrometry
- John M Asara
- , Xiang Zhang
- , Bin Zheng
- , Lisa A Maroney
- , Heather R Christofk
- , Ning Wu
- & Lewis C Cantley
Nature Protocols 1 , 46–51

Rights & permissionsfor article In-gel stable isotope labeling for relative quantification using mass spectrometry . Opens in a new window.
Research | 1 July 2001
Determination of protease cleavage site motifs using mixture-based oriented peptide libraries
Nature Biotechnology 19 , 661–667

Rights & permissionsfor article Determination of protease cleavage site motifs using mixture-based oriented peptide libraries . Opens in a new window.
Research | 23 September 2019 | Open
PIK3CA and MAP3K1 alterations imply luminal A status and are associated with clinical benefit from pan-PI3K inhibitor buparlisib and letrozole in ER+ metastatic breast cancer
npj Breast Cancer 5 , 1–9

Rights & permissionsfor article PIK3CA and MAP3K1 alterations imply luminal A status and are associated with clinical benefit from pan-PI3K inhibitor buparlisib and letrozole in ER+ metastatic breast cancer . Opens in a new window.
Reviews | 9 April 2019
Targeting cancer vulnerabilities with high-dose vitamin C
Nature Reviews Cancer 19 , 271–282

Rights & permissionsfor article Targeting cancer vulnerabilities with high-dose vitamin C . Opens in a new window.
Research | 21 September 2018 | Open
The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation
- Ho-Soo Lee
- , Zhonghui Lin
- , Sunyoung Chae
- , Young-Suk Yoo
- , Byung-Gyu Kim
- , Youngsoo Lee
- , Jared L. Johnson
- , You-Sun Kim
- , Lewis C. Cantley
- , Chang-Woo Lee
- , Hongtao Yu
- & Hyeseong Cho
Nature Communications 9 , 1–13

Rights & permissionsfor article The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation . Opens in a new window.
Reviews | 15 October 2018
Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine
- Michele Carbone
- , Ivano Amelio
- , El Bachir Affar
- , James Brugarolas
- , Lisa A Cannon-Albright
- , Lewis C. Cantley
- , Webster K. Cavenee
- , Zhijian Chen
- , Carlo M. Croce
- , Alan D’ Andrea
- , David Gandara
- , Carlotta Giorgi
- , Wei Jia
- , Qing Lan
- , Tak Wah Mak
- , James L. Manley
- , Katsuhiko Mikoshiba
- , Jose N Onuchic
- , Harvey I. Pass
- , Paolo Pinton
- , Carol Prives
- , Nathaniel Rothman
- , Said M. Sebti
- , James Turkson
- , Xifeng Wu
- , Haining Yang
- , Herbert Yu
- & Gerry Melino
Cell Death and Differentiation 25 , 1885–1904

Rights & permissionsfor article Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine . Opens in a new window.
Research | 4 July 2018
Suppression of insulin feedback enhances the efficacy of PI3K inhibitors
- Benjamin D. Hopkins
- , Chantal Pauli
- , Xing Du
- , Diana G. Wang
- , Xiang Li
- , David Wu
- , Solomon C. Amadiume
- , Marcus D. Goncalves
- , Cindy Hodakoski
- , Mark R. Lundquist
- , Rohan Bareja
- , Yan Ma
- , Emily M. Harris
- , Andrea Sboner
- , Himisha Beltran
- , Mark A. Rubin
- , Siddhartha Mukherjee
- & Lewis C. Cantley
Nature 560 , 499–503

Rights & permissionsfor article Suppression of insulin feedback enhances the efficacy of PI3K inhibitors . Opens in a new window.
Research | 17 January 2018
Chromosomal instability drives metastasis through a cytosolic DNA response
- Samuel F. Bakhoum
- , Bryan Ngo
- , Ashley M. Laughney
- , Julie-Ann Cavallo
- , Charles J. Murphy
- , Peter Ly
- , Pragya Shah
- , Roshan K. Sriram
- , Thomas B. K. Watkins
- , Neil K. Taunk
- , Mercedes Duran
- , Chantal Pauli
- , Christine Shaw
- , Kalyani Chadalavada
- , Vinagolu K. Rajasekhar
- , Giulio Genovese
- , Subramanian Venkatesan
- , Nicolai J. Birkbak
- , Nicholas McGranahan
- , Mark Lundquist
- , Quincey LaPlant
- , John H. Healey
- , Olivier Elemento
- , Christine H. Chung
- , Nancy Y. Lee
- , Marcin Imielenski
- , Gouri Nanjangud
- , Dana Pe’er
- , Don W. Cleveland
- , Simon N. Powell
- , Jan Lammerding
- , Charles Swanton
- & Lewis C. Cantley
Nature 553 , 467–472

Rights & permissionsfor article Chromosomal instability drives metastasis through a cytosolic DNA response . Opens in a new window.
Research | 3 February 2016 | Open
A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2
- Susanne B. Breitkopf
- , Xuemei Yang
- , Michael J. Begley
- , Meghana Kulkarni
- , Yu-Hsin Chiu
- , Alexa B. Turke
- , Jessica Lauriol
- , Min Yuan
- , Jie Qi
- , Jeffrey A. Engelman
- , Pengyu Hong
- , Maria I. Kontaridis
- , Lewis C. Cantley
- , Norbert Perrimon
- & John M. Asara
Scientific Reports 6 , 1–14

Rights & permissionsfor article A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2 . Opens in a new window.
Research | 18 April 2016
Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer
- Evan C. Lien
- , Costas A. Lyssiotis
- , Ashish Juvekar
- , Hai Hu
- , John M. Asara
- , Lewis C. Cantley
- & Alex Toker
Nature Cell Biology 18 , 572–578

Rights & permissionsfor article Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer . Opens in a new window.

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