nature.com search

Loading Filters

Showing 1–21 of 21 results

Loading Filters

Research | 30 November 2020 | Open
Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene
- Flora Doffe
- , Vincent Carbonnier
- , Manon Tissier
- , Bernard Leroy
- , Isabelle Martins
- , Johanna S. M. Mattsson
- , Patrick Micke
- , Sarka Pavlova
- , Sarka Pospisilova
- , Jana Smardova
- , Andreas C. Joerger
- , Klas G. Wiman
- , Guido Kroemer
- & Thierry Soussi
Cell Death and Differentiation , 1–16

Rights & permissionsfor article Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene . Opens in a new window.
Amendments and Corrections | 10 October 2019 | Open
Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277
Cell Death & Disease 10 , 1–2

Rights & permissionsfor article Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277 . Opens in a new window.
Amendments and Corrections | 13 April 2017 | Open
Erratum: APR-246/PRIMA-1^MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase
Cell Death & Disease 8 , e2751–e2751

Rights & permissionsfor article Erratum: APR-246/PRIMA-1MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase . Opens in a new window.
News and Views | 1 August 1997
An old acquaintance resurfaces in human mesothelioma
- Klas G. Wiman
- & George Klein
Nature Medicine 3 , 839–840

Rights & permissionsfor article An old acquaintance resurfaces in human mesothelioma . Opens in a new window.
Research | 2 June 2020 | Open
Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells
- Emarndeena H. Cheteh
- , Victoria Sarne
- , Sophia Ceder
- , Julie Bianchi
- , Martin Augsten
- , Helene Rundqvist
- , Lars Egevad
- , Arne Östman
- & Klas G. Wiman
Cell Death Discovery 6 , 1–14

Rights & permissionsfor article Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells . Opens in a new window.
12 September 2001
Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein
Oncogene 20 , 5466–5474

Rights & permissionsfor article Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein . Opens in a new window.
Research | 1 June 1997
Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain
- Galina Selivanova
- , Violetta Iotsova
- , Ismail Okan
- , Michael Fritsche
- , Marika Ström
- , Bernd Groner
- , Roland C. Grafström
- & Klas G. Wiman
Nature Medicine 3 , 632–638

Rights & permissionsfor article Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain . Opens in a new window.
27 November 1997
Wig-1, a new p53-induced gene encoding a zinc finger protein
- Shohreh Varmeh-Ziaie
- , Ismail Okan
- , Yisong Wang
- , Kristinn P Magnusson
- , Peter Warthoe
- , Michael Strauss
- & Klas G Wiman
Oncogene 15 , 2699–2704

Rights & permissionsfor article Wig-1, a new p53-induced gene encoding a zinc finger protein . Opens in a new window.
10 October 1998
Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation?
- Kristinn P Magnusson
- , Rosa Satalino
- , Wang Qian
- , George Klein
- & Klas G Wiman
Oncogene 17 , 2333–2337

Rights & permissionsfor article Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation? . Opens in a new window.
10 April 2002
Characterization of the p53-rescue drug CP-31398 in vitro and in living cells
Oncogene 21 , 2119–2129

Rights & permissionsfor article Characterization of the p53-rescue drug CP-31398 in vitro and in living cells . Opens in a new window.
20 December 2004
hTERT antagonizes p53-induced apoptosis independently of telomerase activity
Oncogene 24 , 1320–1327

Rights & permissionsfor article hTERT antagonizes p53-induced apoptosis independently of telomerase activity . Opens in a new window.
Research | 1 March 2002
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
Nature Medicine 8 , 282–288

Rights & permissionsfor article Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound . Opens in a new window.
19 April 2001
p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53
Oncogene 20 , 2171–2177

Rights & permissionsfor article p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53 . Opens in a new window.
28 February 2005
PRIMA-1^MET synergizes with cisplatin to induce tumor cell apoptosis
- Vladimir J N Bykov
- , Nicole Zache
- , Helene Stridh
- , Jacob Westman
- , Jan Bergman
- , Galina Selivanova
- & Klas G Wiman
Oncogene 24 , 3484–3491

Rights & permissionsfor article PRIMA-1MET synergizes with cisplatin to induce tumor cell apoptosis . Opens in a new window.
Research | 23 August 2018 | Open
Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246
- Lena Haffo
- , Jun Lu
- , Vladimir J. N. Bykov
- , Sebastin S. Martin
- , Xiaoyuan Ren
- , Lucia Coppo
- , Klas G. Wiman
- & Arne Holmgren
Scientific Reports 8 , 1–10

Rights & permissionsfor article Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246 . Opens in a new window.
Research | 18 April 2018 | Open
APR-246 reactivates mutant p53 by targeting cysteines 124 and 277
Cell Death & Disease 9 , 1–12

Rights & permissionsfor article APR-246 reactivates mutant p53 by targeting cysteines 124 and 277 . Opens in a new window.
Reviews | 15 December 2017
Targeting mutant p53 for efficient cancer therapy
Nature Reviews Cancer 18 , 89–102

Rights & permissionsfor article Targeting mutant p53 for efficient cancer therapy . Opens in a new window.
Research | 1 June 2017 | Open
Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death
- Emarndeena H Cheteh
- , Martin Augsten
- , Helene Rundqvist
- , Julie Bianchi
- , Victoria Sarne
- , Lars Egevad
- , Vladimir JN Bykov
- , Arne Östman
- & Klas G Wiman
Cell Death & Disease 8 , e2848–e2848

Rights & permissionsfor article Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death . Opens in a new window.
Research | 28 March 2017 | Open
Inhibiting the system x_C⁻/glutathione axis selectively targets cancers with mutant-p53 accumulation
- David S. Liu
- , Cuong P. Duong
- , Sue Haupt
- , Karen G. Montgomery
- , Colin M. House
- , Walid J. Azar
- , Helen B. Pearson
- , Oliver M. Fisher
- , Matthew Read
- , Glen R. Guerra
- , Ygal Haupt
- , Carleen Cullinane
- , Klas G. Wiman
- , Lars Abrahmsen
- , Wayne A. Phillips
- & Nicholas J. Clemons
Nature Communications 8 , 1–14

Rights & permissionsfor article Inhibiting the system xC−/glutathione axis selectively targets cancers with mutant-p53 accumulation . Opens in a new window.
26 October 2000
Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells
- Dawei Xu
- , Qian Wang
- , Astrid Gruber
- , Magnus Björkholm
- , Zhiguo Chen
- , Ahmed Zaid
- , Galina Selivanova
- , Curt Peterson
- , Klas G Wiman
- & Pavel Pisa
Oncogene 19 , 5123–5133

Rights & permissionsfor article Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells . Opens in a new window.
6 August 2003
Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblasts
- Mikael S Lindström
- & Klas G Wiman
Oncogene 22 , 4993–5005

Rights & permissionsfor article Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblasts . Opens in a new window.

Refine your results by…

Filters

Filter By:

Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene

Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Erratum: APR-246/PRIMA-1^MET inhibits thioredoxin reductase 1 and converts the enzyme to a dedicated NADPH oxidase

An old acquaintance resurfaces in human mesothelioma

Interleukin-6 derived from cancer-associated fibroblasts attenuates the p53 response to doxorubicin in prostate cancer cells

Human wig-1, a p53 target gene that encodes a growth inhibitory zinc finger protein

Restoration of the growth suppression function of mutant p53 by a synthetic peptide derived from the p53 C-terminal domain

Wig-1, a new p53-induced gene encoding a zinc finger protein

Is conversion of solid into more anoxic ascites tumors associated with p53 inactivation?

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells

hTERT antagonizes p53-induced apoptosis independently of telomerase activity

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound

p14ARF homozygous deletion or MDM2 overexpression in Burkitt lymphoma lines carrying wild type p53

PRIMA-1^MET synergizes with cisplatin to induce tumor cell apoptosis

Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

Targeting mutant p53 for efficient cancer therapy

Human cancer-associated fibroblasts enhance glutathione levels and antagonize drug-induced prostate cancer cell death

Inhibiting the system x_C⁻/glutathione axis selectively targets cancers with mutant-p53 accumulation

Downregulation of telomerase reverse transcriptase mRNA expression by wild type p53 in human tumor cells

Myc and E2F1 induce p53 through p14ARF-independent mechanisms in human fibroblasts

Quick links

Refine your results by…

Filters ​

Filter By:

Search

Quick links

Filters