Showing 1–35 of 35 results
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Amendments and Corrections |
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Amendments and Corrections |
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News and Views |
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Research | | Open
SARS-CoV-2 viral load is associated with increased disease severity and mortality
- Jesse Fajnzylber
- , James Regan
- , Kendyll Coxen
- , Heather Corry
- , Colline Wong
- , Alexandra Rosenthal
- , Daniel Worrall
- , Francoise Giguel
- , Alicja Piechocka-Trocha
- , Caroline Atyeo
- , Stephanie Fischinger
- , Andrew Chan
- , Keith T. Flaherty
- , Kathryn Hall
- , Michael Dougan
- , Edward T. Ryan
- , Elizabeth Gillespie
- , Rida Chishti
- , Yijia Li
- , Nikolaus Jilg
- , Dusan Hanidziar
- , Rebecca M. Baron
- , Lindsey Baden
- , Athe M. Tsibris
- , Katrina A. Armstrong
- , Daniel R. Kuritzkes
- , Galit Alter
- , Bruce D. Walker
- , Xu Yu
- , Jonathan Z. Li
- , Betelihem A. (Betty) Abayneh
- , Patrick Allen
- , Diane Antille
- , Alejandro Balazs
- , Julia Bals
- , Max Barbash
- , Yannic Bartsch
- , Julie Boucau
- , Siobhan Boyce
- , Joan Braley
- , Karen Branch
- , Katherine Broderick
- , Julia Carney
- , Josh Chevalier
- , Manish C. Choudhary
- , Navin Chowdhury
- , Trevor Cordwell
- , George Daley
- , Susan Davidson
- , Michael Desjardins
- , Lauren Donahue
- , David Drew
- , Kevin Einkauf
- , Sampson Elizabeth
- , Ashley Elliman
- , Behzad Etemad
- , Jon Fallon
- , Liz Fedirko
- , Kelsey Finn
- , Jeanne Flannery
- , Pamela Forde
- , Pilar Garcia-Broncano
- , Elise Gettings
- , David Golan
- , Kirsten Goodman
- , Amanda Griffin
- , Sheila Grimmel
- , Kathleen Grinke
- , Ciputra Adijaya Hartana
- , Meg Healy
- , Howard Heller
- , Deborah Henault
- , Grace Holland
- , Chenyang Jiang
- , Hannah Jordan
- , Paulina Kaplonek
- , Elizabeth W. Karlson
- , Marshall Karpell
- , Chantal Kayitesi
- , Evan C. Lam
- , Vlasta LaValle
- , Kristina Lefteri
- , Xiaodong Lian
- , Mathias Lichterfeld
- , Daniel Lingwood
- , Hang Liu
- , Jinqing Liu
- , Kell Lopez
- , Yuting Lu
- , Sarah Luthern
- , Ngoc L. Ly
- , Maureen MacGowan
- , Karen Magispoc
- , Jordan Marchewka
- , Brittani Martino
- , Roseann McNamara
- , Ashlin Michell
- , Ilan Millstrom
- , Noah Miranda
- , Christian Nambu
- , Susan Nelson
- , Marjorie Noone
- , Lewis Novack
- , Claire O’Callaghan
- , Christine Ommerborn
- , Matthew Osborn
- , Lois Chris Pacheco
- , Nicole Phan
- , Shiv Pillai
- , Falisha A. Porto
- , Yelizaveta Rassadkina
- , Alexandra Reissis
- , Francis Ruzicka
- , Kyra Seiger
- , Kathleen Selleck
- , Libera Sessa
- , Arlene Sharpe
- , Christianne Sharr
- , Sally Shin
- , Nishant Singh
- , Sue Slaughenhaupt
- , Kimberly Smith Sheppard
- , Weiwei Sun
- , Xiaoming Sun
- , Elizabeth (Lizzie) Suschana
- , Opeyemi Talabi
- , Hannah Ticheli
- , Scott T. Weiss
- , Vivine Wilson
- & Alex Zhu
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Amendments and Corrections |
Author Correction: PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance
- Vivek Verma
- , Rajeev K Shrimali
- , Shamim Ahmad
- , Winjie Dai
- , Hua Wang
- , Sumin Lu
- , Rahul Nandre
- , Pankaj Gaur
- , Jose Lopez
- , Moshe Sade-Feldman
- , Keren Yizhak
- , Stacey L. Bjorgaard
- , Keith T. Flaherty
- , Jennifer A. Wargo
- , Genevieve M. Boland
- , Ryan J. Sullivan
- , Gad Getz
- , Scott A. Hammond
- , Ming Tan
- , Jingjing Qi
- , Phillip Wong
- , Taha Merghoub
- , Jedd Wolchok
- , Nir Hacohen
- , John E. Janik
- , Mikayel Mkrtichyan
- , Seema Gupta
- & Samir N. Khleif
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Research |
Combined PD-1, BRAF and MEK inhibition in advanced BRAF-mutant melanoma: safety run-in and biomarker cohorts of COMBI-i
- Reinhard Dummer
- , Celeste Lebbé
- , Victoria Atkinson
- , Mario Mandalà
- , Paul D. Nathan
- , Ana Arance
- , Erika Richtig
- , Naoya Yamazaki
- , Caroline Robert
- , Dirk Schadendorf
- , Hussein A. Tawbi
- , Paolo A. Ascierto
- , Antoni Ribas
- , Keith T. Flaherty
- , Neha Pakhle
- , Catarina D. Campbell
- , Daniel Gusenleitner
- , Aisha Masood
- , Jan C. Brase
- , Eduard Gasal
- & Georgina V. Long
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Amendments and Corrections |
Author Correction: PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas
- Hezhe Lu
- , Shujing Liu
- , Gao Zhang
- , Bin Wu
- , Yueyao Zhu
- , Dennie T. Frederick
- , Yi Hu
- , Wenqun Zhong
- , Sergio Randell
- , Norah Sadek
- , Wei Zhang
- , Gang Chen
- , Chaoran Cheng
- , Jingwen Zeng
- , Lawrence W. Wu
- , Jie Zhang
- , Xiaoming Liu
- , Wei Xu
- , Clemens Krepler
- , Katrin Sproesser
- , Min Xiao
- , Benchun Miao
- , Jianglan Liu
- , Claire D. Song
- , Jephrey Y. Liu
- , Giorgos C. Karakousis
- , Lynn M. Schuchter
- , Yiling Lu
- , Gordon Mills
- , Yusheng Cong
- , Jonathan Chernoff
- , Jun Guo
- , Genevieve M. Boland
- , Ryan J. Sullivan
- , Zhi Wei
- , Jeffrey Field
- , Ravi K. Amaravadi
- , Keith T. Flaherty
- , Meenhard Herlyn
- , Xiaowei Xu
- & Wei Guo
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Comments and Opinion |
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Amendments and Corrections |
Correction: Corrigendum: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
- Amanpreet Kaur
- , Marie R. Webster
- , Katie Marchbank
- , Reeti Behera
- , Abibatou Ndoye
- , Curtis H. Kugel
- , Vanessa M. Dang
- , Jessica Appleton
- , Michael P. O’Connell
- , Phil Cheng
- , Alexander A. Valiga
- , Rachel Morissette
- , Nazli B. McDonnell
- , Luigi Ferrucci
- , Andrew V. Kossenkov
- , Katrina Meeth
- , Hsin-Yao Tang
- , Xiangfan Yin
- , William H. Wood
- , Elin Lehrmann
- , Kevin G. Becker
- , Keith T. Flaherty
- , Dennie T. Frederick
- , Jennifer A. Wargo
- , Zachary A. Cooper
- , Michael T. Tetzlaff
- , Courtney Hudgens
- , Katherine M. Aird
- , Rugang Zhang
- , Xiaowei Xu
- , Qin Liu
- , Edmund Bartlett
- , Giorgos Karakousis
- , Zeynep Eroglu
- , Roger S. Lo
- , Matthew Chan
- , Alexander M. Menzies
- , Georgina V. Long
- , Douglas B. Johnson
- , Jeffrey Sosman
- , Bastian Schilling
- , Dirk Schadendorf
- , David W. Speicher
- , Marcus Bosenberg
- , Antoni Ribas
- & Ashani T. Weeraratna
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News and Views |
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Research | | Open
Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
- Julia Boshuizen
- , David W. Vredevoogd
- , Oscar Krijgsman
- , Maarten A. Ligtenberg
- , Stephanie Blankenstein
- , Beaunelle de Bruijn
- , Dennie T. Frederick
- , Juliana C. N. Kenski
- , Mara Parren
- , Marieke Brüggemann
- , Max F. Madu
- , Elisa A. Rozeman
- , Ji-Ying Song
- , Hugo M. Horlings
- , Christian U. Blank
- , Alexander C. J. van Akkooi
- , Keith T. Flaherty
- , Genevieve M. Boland
- & Daniel S. Peeper
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Research | | Open
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Research |
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
- Poulikos I. Poulikakos
- , Yogindra Persaud
- , Manickam Janakiraman
- , Xiangju Kong
- , Charles Ng
- , Gatien Moriceau
- , Hubing Shi
- , Mohammad Atefi
- , Bjoern Titz
- , May Tal Gabay
- , Maayan Salton
- , Kimberly B. Dahlman
- , Madhavi Tadi
- , Jennifer A. Wargo
- , Keith T. Flaherty
- , Mark C. Kelley
- , Tom Misteli
- , Paul B. Chapman
- , Jeffrey A. Sosman
- , Thomas G. Graeber
- , Antoni Ribas
- , Roger S. Lo
- , Neal Rosen
- & David B. Solit
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Reviews |
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Research |
Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma
- Gideon Bollag
- , Peter Hirth
- , James Tsai
- , Jiazhong Zhang
- , Prabha N. Ibrahim
- , Hanna Cho
- , Wayne Spevak
- , Chao Zhang
- , Ying Zhang
- , Gaston Habets
- , Elizabeth A. Burton
- , Bernice Wong
- , Garson Tsang
- , Brian L. West
- , Ben Powell
- , Rafe Shellooe
- , Adhirai Marimuthu
- , Hoa Nguyen
- , Kam Y. J. Zhang
- , Dean R. Artis
- , Joseph Schlessinger
- , Fei Su
- , Brian Higgins
- , Raman Iyer
- , Kurt D’Andrea
- , Astrid Koehler
- , Michael Stumm
- , Paul S. Lin
- , Richard J. Lee
- , Joseph Grippo
- , Igor Puzanov
- , Kevin B. Kim
- , Antoni Ribas
- , Grant A. McArthur
- , Jeffrey A. Sosman
- , Paul B. Chapman
- , Keith T. Flaherty
- , Xiaowei Xu
- , Katherine L. Nathanson
- & Keith Nolop
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Research |
PD-1 blockade in subprimed CD8 cells induces dysfunctional PD-1+CD38hi cells and anti-PD-1 resistance
- Vivek Verma
- , Rajeev K Shrimali
- , Shamim Ahmad
- , Winjie Dai
- , Hua Wang
- , Sumin Lu
- , Rahul Nandre
- , Pankaj Gaur
- , Jose Lopez
- , Moshe Sade-Feldman
- , Keren Yizhak
- , Stacey L. Bjorgaard
- , Keith T. Flaherty
- , Jennifer A. Wargo
- , Genevieve M. Boland
- , Ryan J. Sullivan
- , Gad Getz
- , Scott A. Hammond
- , Ming Tan
- , Jingjing Qi
- , Phillip Wong
- , Taha Merghoub
- , Jedd Wolchok
- , Nir Hacohen
- , John E. Janik
- , Mikayel Mkrtichyan
- , Seema Gupta
- & Samir N. Khleif
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Reviews |
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| Open
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Research | | Open
Resistance to checkpoint blockade therapy through inactivation of antigen presentation
- Moshe Sade-Feldman
- , Yunxin J. Jiao
- , Jonathan H. Chen
- , Michael S. Rooney
- , Michal Barzily-Rokni
- , Jean-Pierre Eliane
- , Stacey L. Bjorgaard
- , Marc R. Hammond
- , Hans Vitzthum
- , Shauna M. Blackmon
- , Dennie T. Frederick
- , Mehlika Hazar-Rethinam
- , Brandon A. Nadres
- , Emily E. Van Seventer
- , Sachet A. Shukla
- , Keren Yizhak
- , John P. Ray
- , Daniel Rosebrock
- , Dimitri Livitz
- , Viktor Adalsteinsson
- , Gad Getz
- , Lyn M. Duncan
- , Bo Li
- , Ryan B. Corcoran
- , Donald P. Lawrence
- , Anat Stemmer-Rachamimov
- , Genevieve M. Boland
- , Dan A. Landau
- , Keith T. Flaherty
- , Ryan J. Sullivan
- & Nir Hacohen
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Research |
PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas
- Hezhe Lu
- , Shujing Liu
- , Gao Zhang
- , Bin Wu
- , Yueyao Zhu
- , Dennie T. Frederick
- , Yi Hu
- , Wenqun Zhong
- , Sergio Randell
- , Norah Sadek
- , Wei Zhang
- , Gang Chen
- , Chaoran Cheng
- , Jingwen Zeng
- , Lawrence W. Wu
- , Jie Zhang
- , Xiaoming Liu
- , Wei Xu
- , Clemens Krepler
- , Katrin Sproesser
- , Min Xiao
- , Benchun Miao
- , Jianglan Liu
- , Claire D. Song
- , Jephrey Y. Liu
- , Giorgos C. Karakousis
- , Lynn M. Schuchter
- , Yiling Lu
- , Gordon Mills
- , Yusheng Cong
- , Jonathan Chernoff
- , Jun Guo
- , Genevieve M. Boland
- , Ryan J. Sullivan
- , Zhi Wei
- , Jeffrey Field
- , Ravi K. Amaravadi
- , Keith T. Flaherty
- , Meenhard Herlyn
- , Xiaowei Xu
- & Wei Guo
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Research |
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Research | | Open
Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors
- Yunching Chen
- , Ya-Chi Liu
- , Yun-Chieh Sung
- , Rakesh R. Ramjiawan
- , Ts-Ting Lin
- , Chih-Chun Chang
- , Kuo-Shyang Jeng
- , Chiung-Fang Chang
- , Chun-Hung Liu
- , Dong-Yu Gao
- , Fu-Fei Hsu
- , Annique M. Duyverman
- , Shuji Kitahara
- , Peigen Huang
- , Simona Dima
- , Irinel Popescu
- , Keith T. Flaherty
- , Andrew X. Zhu
- , Nabeel Bardeesy
- , Rakesh K. Jain
- , Cyril H. Benes
- & Dan G. Duda
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Reviews |
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Research |
sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
- Amanpreet Kaur
- , Marie R. Webster
- , Katie Marchbank
- , Reeti Behera
- , Abibatou Ndoye
- , Curtis H. Kugel
- , Vanessa M. Dang
- , Jessica Appleton
- , Michael P. O’Connell
- , Phil Cheng
- , Alexander A. Valiga
- , Rachel Morissette
- , Nazli B. McDonnell
- , Luigi Ferrucci
- , Andrew V. Kossenkov
- , Katrina Meeth
- , Hsin-Yao Tang
- , Xiangfan Yin
- , William H. Wood
- , Elin Lehrmann
- , Kevin G. Becker
- , Keith T. Flaherty
- , Dennie T. Frederick
- , Jennifer A. Wargo
- , Zachary A. Cooper
- , Michael T. Tetzlaff
- , Courtney Hudgens
- , Katherine M. Aird
- , Rugang Zhang
- , Xiaowei Xu
- , Qin Liu
- , Edmund Bartlett
- , Giorgos Karakousis
- , Zeynep Eroglu
- , Roger S. Lo
- , Matthew Chan
- , Alexander M. Menzies
- , Georgina V. Long
- , Douglas B. Johnson
- , Jeffrey Sosman
- , Bastian Schilling
- , Dirk Schadendorf
- , David W. Speicher
- , Marcus Bosenberg
- , Antoni Ribas
- & Ashani T. Weeraratna
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Research |
The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies
- Luping Lin
- , Amit J Sabnis
- , Elton Chan
- , Victor Olivas
- , Lindsay Cade
- , Evangelos Pazarentzos
- , Saurabh Asthana
- , Dana Neel
- , Jenny Jiacheng Yan
- , Xinyuan Lu
- , Luu Pham
- , Mingxue M Wang
- , Niki Karachaliou
- , Maria Gonzalez Cao
- , Jose Luis Manzano
- , Jose Luis Ramirez
- , Jose Miguel Sanchez Torres
- , Fiamma Buttitta
- , Charles M Rudin
- , Eric A Collisson
- , Alain Algazi
- , Eric Robinson
- , Iman Osman
- , Eva Muñoz-Couselo
- , Javier Cortes
- , Dennie T Frederick
- , Zachary A Cooper
- , Martin McMahon
- , Antonio Marchetti
- , Rafael Rosell
- , Keith T Flaherty
- , Jennifer A Wargo
- & Trever G Bivona
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Reviews |
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Research |
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Research |
Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR
- Miguel Vizoso
- , Humberto J Ferreira
- , Paula Lopez-Serra
- , F Javier Carmona
- , Anna Martínez-Cardús
- , Maria Romina Girotti
- , Alberto Villanueva
- , Sonia Guil
- , Catia Moutinho
- , Julia Liz
- , Anna Portela
- , Holger Heyn
- , Sebastian Moran
- , August Vidal
- , Maria Martinez-Iniesta
- , Jose L Manzano
- , Maria Teresa Fernandez-Figueras
- , Elena Elez
- , Eva Muñoz-Couselo
- , Rafael Botella-Estrada
- , Alfonso Berrocal
- , Fredrik Pontén
- , Joost van den Oord
- , William M Gallagher
- , Dennie T Frederick
- , Keith T Flaherty
- , Ultan McDermott
- , Paul Lorigan
- , Richard Marais
- & Manel Esteller
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Reviews |
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Research |
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
- Ravid Straussman
- , Teppei Morikawa
- , Kevin Shee
- , Michal Barzily-Rokni
- , Zhi Rong Qian
- , Jinyan Du
- , Ashli Davis
- , Margaret M. Mongare
- , Joshua Gould
- , Dennie T. Frederick
- , Zachary A. Cooper
- , Paul B. Chapman
- , David B. Solit
- , Antoni Ribas
- , Roger S. Lo
- , Keith T. Flaherty
- , Shuji Ogino
- , Jennifer A. Wargo
- & Todd R. Golub
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Reviews |
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Research |
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Research |
COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
- Cory M. Johannessen
- , Jesse S. Boehm
- , So Young Kim
- , Sapana R. Thomas
- , Leslie Wardwell
- , Laura A. Johnson
- , Caroline M. Emery
- , Nicolas Stransky
- , Alexandria P. Cogdill
- , Jordi Barretina
- , Giordano Caponigro
- , Haley Hieronymus
- , Ryan R. Murray
- , Kourosh Salehi-Ashtiani
- , David E. Hill
- , Marc Vidal
- , Jean J. Zhao
- , Xiaoping Yang
- , Ozan Alkan
- , Sungjoon Kim
- , Jennifer L. Harris
- , Christopher J. Wilson
- , Vic E. Myer
- , Peter M. Finan
- , David E. Root
- , Thomas M. Roberts
- , Todd Golub
- , Keith T. Flaherty
- , Reinhard Dummer
- , Barbara L. Weber
- , William R. Sellers
- , Robert Schlegel
- , Jennifer A. Wargo
- , William C. Hahn
- & Levi A. Garraway
