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Amendments and Corrections | 23 December 2016
Correction: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
- Fiorenza Fumagalli
- , Julia Noack
- , Timothy J. Bergmann
- , Eduardo Cebollero
- , Giorgia Brambilla Pisoni
- , Elisa Fasana
- , Ilaria Fregno
- , Carmela Galli
- , Marisa Loi
- , Tatiana Soldà
- , Rocco D'Antuono
- , Andrea Raimondi
- , Martin Jung
- , Armin Melnyk
- , Stefan Schorr
- , Anne Schreiber
- , Luca Simonelli
- , Luca Varani
- , Caroline Wilson-Zbinden
- , Oliver Zerbe
- , Kay Hofmann
- , Matthias Peter
- , Manfredo Quadroni
- , Richard Zimmermann
- & Maurizio Molinari
Nature Cell Biology 19 , 76–76

Rights & permissionsfor article Correction: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery . Opens in a new window.
Research | 11 December 2014 | Open
Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s
Scientific Reports 4 , 1–6

Rights & permissionsfor article Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s . Opens in a new window.
Research | 22 November 2009
Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain
- Yogesh Kulathu
- , Masato Akutsu
- , Anja Bremm
- , Kay Hofmann
- & David Komander
Nature Structural & Molecular Biology 16 , 1328–1330

Rights & permissionsfor article Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain . Opens in a new window.
Research | 21 September 2005
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
- Etienne Meylan
- , Joseph Curran
- , Kay Hofmann
- , Darius Moradpour
- , Marco Binder
- , Ralf Bartenschlager
- & Jürg Tschopp
Nature 437 , 1167–1172

Rights & permissionsfor article Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus . Opens in a new window.
19 October 1998
Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle
- Nathalie Lauper
- , Andreas RP Beck
- , Sandrine Cariou
- , Larry Richman
- , Kay Hofmann
- , Walter Reith
- , Joyce M Slingerland
- & Bruno Amati
Oncogene 17 , 2637–2643

Rights & permissionsfor article Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle . Opens in a new window.
Research | 30 June 2005
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
- Thimo Kurz
- , Nurhan Özlü
- , Fabian Rudolf
- , Sean M. O'Rourke
- , Brian Luke
- , Kay Hofmann
- , Anthony A. Hyman
- , Bruce Bowerman
- & Matthias Peter
Nature 435 , 1257–1261

Rights & permissionsfor article The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae . Opens in a new window.
Research | 14 October 1999
Searching for FLASH domains
- Eugene V. Koonin
- , L. Aravind
- , Kay Hofmann
- , Jurg Tschopp
- & Vishva M. Dixit
Nature 401 , 662–662

Rights & permissionsfor article Searching for FLASH domains . Opens in a new window.
Research | 4 April 2004
RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation
- Etienne Meylan
- , Kim Burns
- , Kay Hofmann
- , Vincent Blancheteau
- , Fabio Martinon
- , Michelle Kelliher
- & Jürg Tschopp
Nature Immunology 5 , 503–507

Rights & permissionsfor article RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation . Opens in a new window.
Reviews | 1 September 2010
Selective autophagy: ubiquitin-mediated recognition and beyond
Nature Cell Biology 12 , 836–841

Rights & permissionsfor article Selective autophagy: ubiquitin-mediated recognition and beyond . Opens in a new window.
Reviews | 1 June 2003
When ubiquitin meets ubiquitin receptors: a signalling connection
Nature Reviews Molecular Cell Biology 4 , 491–497

Rights & permissionsfor article When ubiquitin meets ubiquitin receptors: a signalling connection . Opens in a new window.
Research | 14 January 2009
Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA
- Sebastian Leidel
- , Patrick G. A. Pedrioli
- , Tamara Bucher
- , Renée Brost
- , Michael Costanzo
- , Alexander Schmidt
- , Ruedi Aebersold
- , Charles Boone
- , Kay Hofmann
- & Matthias Peter
Nature 458 , 228–232

Rights & permissionsfor article Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA . Opens in a new window.
Research | 27 May 1999
Clathrin self-assembly is mediated by a tandemly repeated superhelix
- Joel A. Ybe
- , Frances M. Brodsky
- , Kay Hofmann
- , Kai Lin
- , Shu-Hui Liu
- , Lin Chen
- , Thomas N. Earnest
- , Robert J. Fletterick
- & Peter K. Hwang
Nature 399 , 371–375

Rights & permissionsfor article Clathrin self-assembly is mediated by a tandemly repeated superhelix . Opens in a new window.
Research | 10 July 1997
Inhibition of death receptor signals by cellular FLIP
- Martin Irmler
- , Margot Thome
- , Michael Hahne
- , Pascal Schneider
- , Kay Hofmann
- , Véronique Steiner
- , Jean-Luc Bodmer
- , Michael Schröter
- , Kim Burns
- , Chantal Mattmann
- , Donata Rimoldi
- , Lars E. French
- & Jürg Tschopp
Nature 388 , 190–195

Rights & permissionsfor article Inhibition of death receptor signals by cellular FLIP . Opens in a new window.
Research | 7 August 1997
Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion
- Yun Wang
- , Masaya Okamoto
- , Frank Schmitz
- , Kay Hofmann
- & Thomas C. Südhof
Nature 388 , 593–598

Rights & permissionsfor article Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion . Opens in a new window.
Research | 15 August 2019 | Open
Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain
Nature Communications 10 , 1–12

Rights & permissionsfor article Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain . Opens in a new window.
Research | 23 February 2018 | Open
A family of unconventional deubiquitinases with modular chain specificity determinants
- Thomas Hermanns
- , Christian Pichlo
- , Ilka Woiwode
- , Karsten Klopffleisch
- , Katharina F. Witting
- , Huib Ovaa
- , Ulrich Baumann
- & Kay Hofmann
Nature Communications 9 , 1–13

Rights & permissionsfor article A family of unconventional deubiquitinases with modular chain specificity determinants . Opens in a new window.
Research | 11 April 2018
Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity
Nature 556 , 381–385

Rights & permissionsfor article Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity . Opens in a new window.
Research | 27 July 2016 | Open
Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog
- Monika Sivá
- , Michal Svoboda
- , Václav Veverka
- , Jean-François Trempe
- , Kay Hofmann
- , Milan Kožíšek
- , Rozálie Hexnerová
- , František Sedlák
- , Jan Belza
- , Jiří Brynda
- , Pavel Šácha
- , Martin Hubálek
- , Jana Starková
- , Iva Flaisigová
- , Jan Konvalinka
- & Klára Grantz Šašková
Scientific Reports 6 , 1–15

Rights & permissionsfor article Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog . Opens in a new window.
Research | 17 October 2016
Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery
- Fiorenza Fumagalli
- , Julia Noack
- , Timothy J. Bergmann
- , Eduardo Cebollero
- , Giorgia Brambilla Pisoni
- , Elisa Fasana
- , Ilaria Fregno
- , Carmela Galli
- , Marisa Loi
- , Tatiana Soldà
- , Rocco D’Antuono
- , Andrea Raimondi
- , Martin Jung
- , Armin Melnyk
- , Stefan Schorr
- , Anne Schreiber
- , Luca Simonelli
- , Luca Varani
- , Caroline Wilson-Zbinden
- , Oliver Zerbe
- , Kay Hofmann
- , Matthias Peter
- , Manfredo Quadroni
- , Richard Zimmermann
- & Maurizio Molinari
Nature Cell Biology 18 , 1173–1184

Rights & permissionsfor article Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery . Opens in a new window.
Research | 2 November 2015
A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly
- Nathalie Eisenhardt
- , Viduth K Chaugule
- , Stefanie Koidl
- , Mathias Droescher
- , Esen Dogan
- , Jan Rettich
- , Päivi Sutinen
- , Susumu Y Imanishi
- , Kay Hofmann
- , Jorma J Palvimo
- & Andrea Pichler
Nature Structural & Molecular Biology 22 , 959–967

Rights & permissionsfor article A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly . Opens in a new window.
Research | 28 September 2014
Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features
- Davor Lessel
- , Bruno Vaz
- , Swagata Halder
- , Paul J Lockhart
- , Ivana Marinovic-Terzic
- , Jaime Lopez-Mosqueda
- , Melanie Philipp
- , Joe C H Sim
- , Katherine R Smith
- , Judith Oehler
- , Elisa Cabrera
- , Raimundo Freire
- , Kate Pope
- , Amsha Nahid
- , Fiona Norris
- , Richard J Leventer
- , Martin B Delatycki
- , Gotthold Barbi
- , Simon von Ameln
- , Josef Högel
- , Marina Degoricija
- , Regina Fertig
- , Martin D Burkhalter
- , Kay Hofmann
- , Holger Thiele
- , Janine Altmüller
- , Gudrun Nürnberg
- , Peter Nürnberg
- , Melanie Bahlo
- , George M Martin
- , Cora M Aalfs
- , Junko Oshima
- , Janos Terzic
- , David J Amor
- , Ivan Dikic
- , Kristijan Ramadan
- & Christian Kubisch
Nature Genetics 46 , 1239–1244

Rights & permissionsfor article Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features . Opens in a new window.
Research | 22 May 2008
Proteasome subunit Rpn13 is a novel ubiquitin receptor
- Koraljka Husnjak
- , Suzanne Elsasser
- , Naixia Zhang
- , Xiang Chen
- , Leah Randles
- , Yuan Shi
- , Kay Hofmann
- , Kylie J. Walters
- , Daniel Finley
- & Ivan Dikic
Nature 453 , 481–488

Rights & permissionsfor article Proteasome subunit Rpn13 is a novel ubiquitin receptor . Opens in a new window.
Research | 3 March 2013
Ubiquitylation-dependent localization of PLK1 in mitosis
- Jochen Beck
- , Sarah Maerki
- , Markus Posch
- , Thibaud Metzger
- , Avinash Persaud
- , Hartmut Scheel
- , Kay Hofmann
- , Daniela Rotin
- , Patrick Pedrioli
- , Jason R. Swedlow
- , Matthias Peter
- & Izabela Sumara
Nature Cell Biology 15 , 430–439

Rights & permissionsfor article Ubiquitylation-dependent localization of PLK1 in mitosis . Opens in a new window.
Research | 3 April 1997
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors
- Margot Thome
- , Pascal Schneider
- , Kay Hofmann
- , Helmut Fickenscher
- , Edgar Meinl
- , Frank Neipel
- , Chantal Mattmann
- , Kim Burns
- , Jean-Luc Bodmer
- , Michael Schröter
- , Carsten Scaffidi
- , Peter H. Krammer
- , Marcus E. Peter
- & Jürg Tschopp
Nature 386 , 517–521

Rights & permissionsfor article Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors . Opens in a new window.
Research | 17 December 2008
WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity
- Andrew Xiao
- , Haitao Li
- , David Shechter
- , Sung Hee Ahn
- , Laura A. Fabrizio
- , Hediye Erdjument-Bromage
- , Satoko Ishibe-Murakami
- , Bin Wang
- , Paul Tempst
- , Kay Hofmann
- , Dinshaw J. Patel
- , Stephen J. Elledge
- & C. David Allis
Nature 457 , 57–62

Rights & permissionsfor article WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity . Opens in a new window.

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Correction: Corrigendum: Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery

Evolutionary link between metazoan RHIM motif and prion-forming domain of fungal heterokaryon incompatibility factor HET-s/HET-s

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae

Searching for FLASH domains

RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation

Selective autophagy: ubiquitin-mediated recognition and beyond

When ubiquitin meets ubiquitin receptors: a signalling connection

Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA

Clathrin self-assembly is mediated by a tandemly repeated superhelix

Inhibition of death receptor signals by cellular FLIP

Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain

A family of unconventional deubiquitinases with modular chain specificity determinants

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog

Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery

A new vertebrate SUMO enzyme family reveals insights into SUMO-chain assembly

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features

Proteasome subunit Rpn13 is a novel ubiquitin receptor

Ubiquitylation-dependent localization of PLK1 in mitosis

Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

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