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Research | 7 January 2021
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
- Xing Yi Woo
- , Jessica Giordano
- , Anuj Srivastava
- , Zi-Ming Zhao
- , Michael W. Lloyd
- , Roebi de Bruijn
- , Yun-Suhk Suh
- , Rajesh Patidar
- , Li Chen
- , Sandra Scherer
- , Matthew H. Bailey
- , Chieh-Hsiang Yang
- , Emilio Cortes-Sanchez
- , Yuanxin Xi
- , Jing Wang
- , Jayamanna Wickramasinghe
- , Andrew V. Kossenkov
- , Vito W. Rebecca
- , Hua Sun
- , R. Jay Mashl
- , Sherri R. Davies
- , Ryan Jeon
- , Christian Frech
- , Jelena Randjelovic
- , Jacqueline Rosains
- , Francesco Galimi
- , Andrea Bertotti
- , Adam Lafferty
- , Alice C. O’Farrell
- , Elodie Modave
- , Diether Lambrechts
- , Petra ter Brugge
- , Violeta Serra
- , Elisabetta Marangoni
- , Rania El Botty
- , Hyunsoo Kim
- , Jong-Il Kim
- , Han-Kwang Yang
- , Charles Lee
- , Dennis A. Dean II
- , Brandi Davis-Dusenbery
- , Yvonne A. Evrard
- , James H. Doroshow
- , Alana L. Welm
- , Bryan E. Welm
- , Michael T. Lewis
- , Bingliang Fang
- , Jack A. Roth
- , Funda Meric-Bernstam
- , Meenhard Herlyn
- , Michael A. Davies
- , Li Ding
- , Shunqiang Li
- , Ramaswamy Govindan
- , Claudio Isella
- , Jeffrey A. Moscow
- , Livio Trusolino
- , Annette T. Byrne
- , Jos Jonkers
- , Carol J. Bult
- , Enzo Medico
- , Jeffrey H. Chuang
- , Matthew H. Bailey
- , Vito W. Rebecca
- , Michael A. Davies
- , Peter N. Robinson
- , Brian J. Sanderson
- , Steven B. Neuhauser
- , Lacey E. Dobrolecki
- , Xiaofeng Zheng
- , Mourad Majidi
- , Ran Zhang
- , Xiaoshan Zhang
- , Argun Akcakanat
- , Kurt W. Evans
- , Timothy A. Yap
- , Dali Li
- , Erkan Yucan
- , Christopher D. Lanier
- , Turcin Saridogan
- , Bryce P. Kirby
- , Min Jin Ha
- , Huiqin Chen
- , Scott Kopetz
- , David G. Menter
- , Jianhua Zhang
- , Shannon N. Westin
- , Michael P. Kim
- , Bingbing Dai
- , Don L. Gibbons
- , Coya Tapia
- , Vanessa B. Jensen
- , Gao Boning
- , John D. Minna
- , Hyunsil Park
- , Brenda C. Timmons
- , Luc Girard
- , Dylan Fingerman
- , Qin Liu
- , Rajasekharan Somasundaram
- , Min Xiao
- , Vashisht G. Yennu-Nanda
- , Michael T. Tetzlaff
- , Xiaowei Xu
- , Katherine L. Nathanson
- , Song Cao
- , Feng Chen
- , John F. DiPersio
- , Kian H. Lim
- , Cynthia X. Ma
- , Fernanda M. Rodriguez
- , Brian A. Van Tine
- , Andrea Wang-Gillam
- , Michael C. Wendl
- , Yige Wu
- , Matthew A. Wyczalkowski
- , Lijun Yao
- , Reyka Jayasinghe
- , Rebecca L. Aft
- , Ryan C. Fields
- , Jingqin Luo
- , Katherine C. Fuh
- , Vicki Chin
- , John DiGiovanna
- , Jeffrey Grover
- , Soner Koc
- , Sara Seepo
- , Tiffany Wallace
- , Chong-Xian Pan
- , Moon S. Chen Jr
- , Luis G. Carvajal-Carmona
- , Amanda R. Kirane
- , May Cho
- , David R. Gandara
- , Jonathan W. Riess
- , Tiffany Le
- , Ralph W. deVere White
- , Clifford G. Tepper
- , Hongyong Zhang
- , Nicole B. Coggins
- , Paul Lott
- , Ana Estrada
- , Ted Toal
- , Alexa Morales Arana
- , Guadalupe Polanco-Echeverry
- , Sienna Rocha
- , Ai-Hong Ma
- , Nicholas Mitsiades
- , Salma Kaochar
- , Bert W. O’Malley
- , Matthew J. Ellis
- , Susan G. Hilsenbeck
- , Michael Ittmann
- , Roebi de Bruijn
- , Petra ter Brugge
- , Simona Corso
- , Alessandro Fiori
- , Silvia Giordano
- , Marieke van de Ven
- , Daniel S. Peeper
- , Ian Miller
- , Cristina Bernadó
- , Beatriz Morancho
- , Lorena Ramírez
- , Joaquín Arribas
- , Héctor G. Palmer
- , Alejandro Piris-Gimenez
- , Laura Soucek
- , Ahmed Dahmani
- , Elodie Montaudon
- , Fariba Nemati
- , Virginie Dangles-Marie
- , Didier Decaudin
- , Sergio Roman-Roman
- , Denis G. Alférez
- , Katherine Spence
- , Robert B. Clarke
- , Mohamed Bentires-Alj
- , David K. Chang
- , Andrew V. Biankin
- , Alejandra Bruna
- , Martin O’Reilly
- , Carlos Caldas
- , Oriol Casanovas
- , Eva Gonzalez-Suarez
- , Purificacíon Muñoz
- , Alberto Villanueva
- , Nathalie Conte
- , Jeremy Mason
- , Ross Thorne
- , Terrence F. Meehan
- , Helen Parkinson
- , Zdenka Dudova
- , Ales Křenek
- , Dalibor Stuchlík
- , Olivier Elemento
- , Giorgio Inghirami
- , Anna Golebiewska
- , Simone P. Niclou
- , G. Bea A. Wisman
- , Steven de Jong
- , Petra Kralova
- , Radislav Sedlacek
- , Elisa Claeys
- , Eleonora Leucci
- , Massimiliano Borsani
- , Luisa Lanfrancone
- , Pier Giuseppe Pelicci
- , Gunhild Mari Mælandsmo
- , Jens Henrik Norum
- & Emilie Vinolo
Nature Genetics 53 , 86–99

Rights & permissionsfor article Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts . Opens in a new window.
Amendments and Corrections | 1 December 2017
Erratum: Small-cell lung cancer: what we know, what we need to know and the path forward
Nature Reviews Cancer 17 , 765–765

Rights & permissionsfor article Erratum: Small-cell lung cancer: what we know, what we need to know and the path forward . Opens in a new window.
Research | 30 November 2020
The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer
- Jiyeon Kim
- , Hyun Min Lee
- , Feng Cai
- , Bookyung Ko
- , Chendong Yang
- , Elizabeth L. Lieu
- , Nefertiti Muhammad
- , Shawn Rhyne
- , Kailong Li
- , Mohamed Haloul
- , Wen Gu
- , Brandon Faubert
- , Akash K. Kaushik
- , Ling Cai
- , Sahba Kasiri
- , Ummay Marriam
- , Kien Nham
- , Luc Girard
- , Hui Wang
- , Xiankai Sun
- , James Kim
- , John D. Minna
- , Keziban Unsal-Kacmaz
- & Ralph J. DeBerardinis
Nature Metabolism 2 , 1401–1412

Rights & permissionsfor article The hexosamine biosynthesis pathway is a targetable liability in <i>KRAS</i>/<i>LKB1</i> mutant lung cancer . Opens in a new window.
Amendments and Corrections | 29 March 2016
Erratum: NRF2 regulates serine biosynthesis in non–small cell lung cancer
- Gina M DeNicola
- , Pei-Hsuan Chen
- , Edouard Mullarky
- , Jessica A Sudderth
- , Zeping Hu
- , David Wu
- , Hao Tang
- , Yang Xie
- , John M Asara
- , Kenneth E Huffman
- , Ignacio I Wistuba
- , John D Minna
- , Ralph J DeBerardinis
- & Lewis C Cantley
Nature Genetics 48 , 473–473

Rights & permissionsfor article Erratum: NRF2 regulates serine biosynthesis in non–small cell lung cancer . Opens in a new window.
Amendments and Corrections | 1 May 2019
Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells
- Jiyeon Kim
- , Zeping Hu
- , Ling Cai
- , Kailong Li
- , Eunhee Choi
- , Brandon Faubert
- , Divya Bezwada
- , Jaime Rodriguez-Canales
- , Pamela Villalobos
- , Yu-Fen Lin
- , Min Ni
- , Kenneth E. Huffman
- , Luc Girard
- , Lauren A. Byers
- , Keziban Unsal-Kacmaz
- , Christopher G. Peña
- , John V. Heymach
- , Els Wauters
- , Johan Vansteenkiste
- , Diego H. Castrillon
- , Benjamin P. C. Chen
- , Ignacio Wistuba
- , Diether Lambrechts
- , Jian Xu
- , John D. Minna
- & Ralph J. DeBerardinis
Nature 569 , E4–E4

Rights & permissionsfor article Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells . Opens in a new window.
Amendments and Corrections | 7 June 2019
Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data
- Charles M. Rudin
- , John T. Poirier
- , Lauren Averett Byers
- , Caroline Dive
- , Afshin Dowlati
- , Julie George
- , John V. Heymach
- , Jane E. Johnson
- , Jonathan M. Lehman
- , David MacPherson
- , Pierre P. Massion
- , John D. Minna
- , Trudy G. Oliver
- , Vito Quaranta
- , Julien Sage
- , Roman K. Thomas
- , Christopher R. Vakoc
- & Adi F. Gazdar
Nature Reviews Cancer 19 , 415–415

Rights & permissionsfor article Author Correction: Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data . Opens in a new window.
Research Highlights | 2 July 2019
AIF: an acquired metabolic liability in lung cancer
Cell Research 29 , 607–608

Rights & permissionsfor article AIF: an acquired metabolic liability in lung cancer . Opens in a new window.
News and Views | 9 April 2018
Evaluating tumor-suppressor gene combinations
- James Kim
- & John D. Minna
Nature Genetics 50 , 480–482

Rights & permissionsfor article Evaluating tumor-suppressor gene combinations . Opens in a new window.
Amendments and Corrections | 28 January 2015
Correction: Corrigendum: A pan-cancer proteomic perspective on The Cancer Genome Atlas
- Rehan Akbani
- , Patrick Kwok Shing Ng
- , Henrica M.J. Werner
- , Maria Shahmoradgoli
- , Fan Zhang
- , Zhenlin Ju
- , Wenbin Liu
- , Ji-Yeon Yang
- , Kosuke Yoshihara
- , Jun Li
- , Shiyun Ling
- , Elena G. Seviour
- , Prahlad T. Ram
- , John D. Minna
- , Lixia Diao
- , Pan Tong
- , John V. Heymach
- , Steven M. Hill
- , Frank Dondelinger
- , Nicolas Städler
- , Lauren A. Byers
- , Funda Meric-Bernstam
- , John N. Weinstein
- , Bradley M. Broom
- , Roeland G.W. Verhaak
- , Han Liang
- , Sach Mukherjee
- , Yiling Lu
- & Gordon B. Mills
Nature Communications 6 , 1–1

Rights & permissionsfor article Correction: Corrigendum: A pan-cancer proteomic perspective on The Cancer Genome Atlas . Opens in a new window.
News and Views | 1 August 2008
Predicting the future for people with lung cancer
- Yang Xie
- & John D Minna
Nature Medicine 14 , 812–813

Rights & permissionsfor article Predicting the future for people with lung cancer . Opens in a new window.
1 January 2005
Erlotinib hydrochloride
Nature Reviews Drug Discovery 4 , 13–14

Rights & permissionsfor article Erlotinib hydrochloride . Opens in a new window.
1 November 2004
The impact of epidermal-growth-factor-receptor mutations in response to lung-cancer therapy
- Jonathan E Dowell
- & John D Minna
Nature Reviews Clinical Oncology 1 , 2–3

Rights & permissionsfor article The impact of epidermal-growth-factor-receptor mutations in response to lung-cancer therapy . Opens in a new window.
1 April 2006
EGFR mutations and molecularly targeted therapy: a new era in the treatment of lung cancer
- Jonathan E Dowell
- & John D Minna
Nature Reviews Clinical Oncology 3 , 170–171

Rights & permissionsfor article <i>EGFR</i> mutations and molecularly targeted therapy: a new era in the treatment of lung cancer . Opens in a new window.
Research | 4 November 2007 | Open
Characterizing the cancer genome in lung adenocarcinoma
- Barbara A. Weir
- , Michele S. Woo
- , Gad Getz
- , Sven Perner
- , Li Ding
- , Rameen Beroukhim
- , William M. Lin
- , Michael A. Province
- , Aldi Kraja
- , Laura A. Johnson
- , Kinjal Shah
- , Mitsuo Sato
- , Roman K. Thomas
- , Justine A. Barletta
- , Ingrid B. Borecki
- , Stephen Broderick
- , Andrew C. Chang
- , Derek Y. Chiang
- , Lucian R. Chirieac
- , Jeonghee Cho
- , Yoshitaka Fujii
- , Adi F. Gazdar
- , Thomas Giordano
- , Heidi Greulich
- , Megan Hanna
- , Bruce E. Johnson
- , Mark G. Kris
- , Alex Lash
- , Ling Lin
- , Neal Lindeman
- , Elaine R. Mardis
- , John D. McPherson
- , John D. Minna
- , Margaret B. Morgan
- , Mark Nadel
- , Mark B. Orringer
- , John R. Osborne
- , Brad Ozenberger
- , Alex H. Ramos
- , James Robinson
- , Jack A. Roth
- , Valerie Rusch
- , Hidefumi Sasaki
- , Frances Shepherd
- , Carrie Sougnez
- , Margaret R. Spitz
- , Ming-Sound Tsao
- , David Twomey
- , Roel G. W. Verhaak
- , George M. Weinstock
- , David A. Wheeler
- , Wendy Winckler
- , Akihiko Yoshizawa
- , Soyoung Yu
- , Maureen F. Zakowski
- , Qunyuan Zhang
- , David G. Beer
- , Ignacio I. Wistuba
- , Mark A. Watson
- , Levi A. Garraway
- , Marc Ladanyi
- , William D. Travis
- , William Pao
- , Mark A. Rubin
- , Stacey B. Gabriel
- , Richard A. Gibbs
- , Harold E. Varmus
- , Richard K. Wilson
- , Eric S. Lander
- & Matthew Meyerson
Nature 450 , 893–898

Rights & permissionsfor article Characterizing the cancer genome in lung adenocarcinoma . Opens in a new window.
Research | 20 April 2020
eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer
- Shruthy Suresh
- , BeiBei Chen
- , Jingfei Zhu
- , Ryan J. Golden
- , Changzheng Lu
- , Bret M. Evers
- , Nicole Novaresi
- , Bethany Smith
- , Xiaowei Zhan
- , Vanessa Schmid
- , Sojeong Jun
- , Chelsea M. Karacz
- , Michael Peyton
- , Lin Zhong
- , Zhuoyu Wen
- , Adwait Amod Sathe
- , Chao Xing
- , Carmen Behrens
- , Ignacio I. Wistuba
- , Guanghua Xiao
- , Yang Xie
- , Yang-Xin Fu
- , John D. Minna
- , Joshua T. Mendell
- & Kathryn A. O’Donnell
Nature Cancer 1 , 533–545

Rights & permissionsfor article eIF5B drives integrated stress response-dependent translation of PD-L1 in lung cancer . Opens in a new window.
Research | 6 April 2020
EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer
- Ke Gong
- , Gao Guo
- , Nishah Panchani
- , Matthew E. Bender
- , David E. Gerber
- , John D. Minna
- , Farjana Fattah
- , Boning Gao
- , Michael Peyton
- , Kemp Kernstine
- , Bipasha Mukherjee
- , Sandeep Burma
- , Cheng-Ming Chiang
- , Shanrong Zhang
- , Adwait Amod Sathe
- , Chao Xing
- , Kathryn H. Dao
- , Dawen Zhao
- , Esra A. Akbay
- & Amyn A. Habib
Nature Cancer 1 , 394–409

Rights & permissionsfor article EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer . Opens in a new window.
Research | 12 February 2020
Mechanical regulation of glycolysis via cytoskeleton architecture
- Jin Suk Park
- , Christoph J. Burckhardt
- , Rossana Lazcano
- , Luisa M. Solis
- , Tadamoto Isogai
- , Linqing Li
- , Christopher S. Chen
- , Boning Gao
- , John D. Minna
- , Robert Bachoo
- , Ralph J. DeBerardinis
- & Gaudenz Danuser
Nature 578 , 621–626

Rights & permissionsfor article Mechanical regulation of glycolysis via cytoskeleton architecture . Opens in a new window.
Research | 29 August 1985
Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer
- Frank Cuttitta
- , Desmond N. Carney
- , James Mulshine
- , Terry W. Moody
- , Joseph Fedorko
- , Adam Fischler
- & John D. Minna
Nature 316 , 823–826

Rights & permissionsfor article Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer . Opens in a new window.
28 February 2005
The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer
- Ikuo Sekine
- , Mitsuo Sato
- , Noriaki Sunaga
- , Shinichi Toyooka
- , Michael Peyton
- , Ramon Parsons
- , Weidong Wang
- , Adi F Gazdar
- & John D Minna
Oncogene 24 , 2735–2738

Rights & permissionsfor article The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer . Opens in a new window.
9 April 2001
Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers
- Eva Forgacs
- , Jonathan D Wren
- , Craig Kamibayashi
- , Masashi Kondo
- , Xie L Xu
- , Sanford Markowitz
- , Gail E Tomlinson
- , Carolyn Y Muller
- , Adi F Gazdar
- , Harold R Garner
- & John D Minna
Oncogene 20 , 1005–1009

Rights & permissionsfor article Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers . Opens in a new window.
2 February 1999
Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
- Ignacio I Wistuba
- , Carmen Behrens
- , Sara Milchgrub
- , David Bryant
- , Jaclyn Hung
- , John D Minna
- & Adi F Gazdar
Oncogene 18 , 643–650

Rights & permissionsfor article Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma . Opens in a new window.
22 March 2001
Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours
- Angelo Agathanggelou
- , Sofia Honorio
- , Donia P Macartney
- , Alonso Martinez
- , Ashraf Dallol
- , Janet Rader
- , Paul Fullwood
- , Anita Chauhan
- , Rosemary Walker
- , Jacqueline A Shaw
- , Shigeto Hosoe
- , Michael I Lerman
- , John D Minna
- , Eamonn R Maher
- & Farida Latif
Oncogene 20 , 1509–1518

Rights & permissionsfor article Methylation associated inactivation of <i>RASSF1A</i> from region 3p21.3 in lung, breast and ovarian tumours . Opens in a new window.
22 September 1998
Mutation analysis of the PTEN/MMAC1 gene in lung cancer
- Eva Forgacs
- , Eric J Biesterveld
- , Yoshitaka Sekido
- , Kwun Fong
- , Sabeeha Muneer
- , Ignacio I Wistuba
- , Sara Milchgrub
- , Ruth Brezinschek
- , Arvind Virmani
- , Adi F Gazdar
- & John D Minna
Oncogene 17 , 1557–1565

Rights & permissionsfor article Mutation analysis of the <i>PTEN/MMAC1</i> gene in lung cancer . Opens in a new window.
4 September 1998
TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer
- Yun Oh
- , Monja L Proctor
- , You Hong Fan
- , Li-Kuo Su
- , Waun Ki Hong
- , Kwun M Fong
- , Yoshitaka S Sekido
- , Adi F Gazdar
- , John D Minna
- & Li Mao
Oncogene 17 , 1141–1148

Rights & permissionsfor article <i>TSG101</i> is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer . Opens in a new window.
14 June 2002
Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines
- Kenichi Harada
- , Shinichi Toyooka
- , Anirban Maitra
- , Riichiroh Maruyama
- , Kiyomi O Toyooka
- , Charles F Timmons
- , Gail E Tomlinson
- , Domenico Mastrangelo
- , Robert J Hay
- , John D Minna
- & Adi F Gazdar
Oncogene 21 , 4345–4349

Rights & permissionsfor article Aberrant promoter methylation and silencing of the <i>RASSF1A</i> gene in pediatric tumors and cell lines . Opens in a new window.
14 June 2002
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells
Oncogene 21 , 4340–4344

Rights & permissionsfor article Progressive aberrant methylation of the <i>RASSF1A</i> gene in simian virus 40 infected human mesothelial cells . Opens in a new window.
Research | 13 July 1978
Conservation of autosomal gene synteny groups in mouse and man
Nature 274 , 160–163

Rights & permissionsfor article Conservation of autosomal gene synteny groups in mouse and man . Opens in a new window.
Research | 10 November 1983
Amplification and expression of the c-myc oncogene in human lung cancer cell lines
Nature 306 , 194–196

Rights & permissionsfor article Amplification and expression of the c-<i>myc</i> oncogene in human lung cancer cell lines . Opens in a new window.
7 May 2002
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers
- Ashraf Dallol
- , Eva Forgacs
- , Alonso Martinez
- , Yoshitaka Sekido
- , Rosemary Walker
- , Takeshi Kishida
- , Pamela Rabbitts
- , Eamonn R Maher
- , John D Minna
- & Farida Latif
Oncogene 21 , 3020–3028

Rights & permissionsfor article Tumour specific promoter region methylation of the human homologue of the <i>Drosophila Roundabout</i> gene <i>DUTT1 (ROBO1)</i> in human cancers . Opens in a new window.
Research | 1 July 1978
Mouse chromosome 5 codes for ecotropic murine leukaemia virus cell-surface receptor
- HERBERT K. OIE
- , ADI F. GAZDAR
- , PETER A. LALLEY
- , EDWARD K. RUSSELL
- , JOHN D. MINNA
- , JOSEPH DELARCO
- , GEORGE J. TODARO
- & UTA FRANCKE
Nature 274 , 60–62

Rights & permissionsfor article Mouse chromosome 5 codes for ecotropic murine leukaemia virus cell-surface receptor . Opens in a new window.
Research | 27 February 1986
Differential expression of myc family genes during murine development
Nature 319 , 780–783

Rights & permissionsfor article Differential expression of <i>myc</i> family genes during murine development . Opens in a new window.
12 October 2001
Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells
- Masashi Kondo
- , Lin Ji
- , Craig Kamibayashi
- , Yoshio Tomizawa
- , Dwight Randle
- , Yoshitaka Sekido
- , Jun Yokota
- , Vladimir Kashuba
- , Eugene Zabarovsky
- , Igor Kuzmin
- , Michael Lerman
- , Jack Roth
- & John D Minna
Oncogene 20 , 6258–6262

Rights & permissionsfor article Overexpression of candidate tumor suppressor gene <i>FUS1</i> isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells . Opens in a new window.
1 September 2010
Towards patient-based cancer therapeutics
- Stuart L Schreiber
- , Alykhan F Shamji
- , Paul A Clemons
- , Cindy Hon
- , Angela N Koehler
- , Benito Munoz
- , Michelle Palmer
- , Andrew M Stern
- , Bridget K Wagner
- , Scott Powers
- , Scott W Lowe
- , Xuecui Guo
- , Alex Krasnitz
- , Eric T Sawey
- , Raffaella Sordella
- , Lincoln Stein
- , Lloyd C Trotman
- , Andrea Califano
- , Riccardo Dalla-Favera
- , Adolfo Ferrando
- , Antonio Iavarone
- , Laura Pasqualucci
- , José Silva
- , Brent R Stockwell
- , William C Hahn
- , Lynda Chin
- , Ronald A DePinho
- , Jesse S Boehm
- , Shuba Gopal
- , Alan Huang
- , David E Root
- , Barbara A Weir
- , Daniela S Gerhard
- , Jean Claude Zenklusen
- , Michael G Roth
- , Michael A White
- , John D Minna
- , John B MacMillan
- & Bruce A Posner
Nature Biotechnology 28 , 904–906

Rights & permissionsfor article Towards patient-based cancer therapeutics . Opens in a new window.
11 June 2003
Molecular processes of chromosome 9p21 deletions in human cancers
- Shigeru Sasaki
- , Yukiko Kitagawa
- , Yoshitaka Sekido
- , John D Minna
- , Hiroyuki Kuwano
- , Jun Yokota
- & Takashi Kohno
Oncogene 22 , 3792–3798

Rights & permissionsfor article Molecular processes of chromosome 9p21 deletions in human cancers . Opens in a new window.
21 June 2004
Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene
- Jingfeng Li
- , Fuli Wang
- , Alexey Protopopov
- , Alena Malyukova
- , Vladimir Kashuba
- , John D Minna
- , Michael I Lerman
- , George Klein
- & Eugene Zabarovsky
Oncogene 23 , 5941–5949

Rights & permissionsfor article Inactivation of <i>RASSF1C</i> during <i>in vivo</i> tumor growth identifies it as a tumor suppressor gene . Opens in a new window.
6 June 2005
Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation
- Sabine Zöchbauer-Müller
- , Kwun M Fong
- , Joseph Geradts
- , Xie Xu
- , Sonja Seidl
- , Adelheid End-Pfützenreuter
- , György Lang
- , Gerwin Heller
- , Christoph C Zielinski
- , Adi F Gazdar
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Oncogene 24 , 6249–6255

Rights & permissionsfor article Expression of the candidate tumor suppressor gene <i>hSRBC</i> is frequently lost in primary lung cancers with and without DNA methylation . Opens in a new window.
21 June 2004
Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas
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Rights & permissionsfor article Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas . Opens in a new window.
17 July 2001
Genetic alteration of the β-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion
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Oncogene 20 , 4249–4257

Rights & permissionsfor article Genetic alteration of the β-catenin gene (<i>CTNNB1</i>) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion . Opens in a new window.
3 October 2005
Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas
Oncogene 25 , 959–968

Rights & permissionsfor article Expression and methylation pattern of <i>TSLC1</i> cascade genes in lung carcinomas . Opens in a new window.
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Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo
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Rights & permissionsfor article Liposomal vector mediated delivery of the 3p <i>FUS1</i> gene demonstrates potent antitumor activity against human lung cancer <i>in vivo</i> . Opens in a new window.
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Human x mouse hybrid cells segregating mouse chromosomes and isozymes
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Nature 252 , 401–404

Rights & permissionsfor article Human x mouse hybrid cells segregating mouse chromosomes and isozymes . Opens in a new window.
1 April 1999
Enrichment of epithelial cells for molecular studies
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Nature Medicine 5 , 459–462

Rights & permissionsfor article Enrichment of epithelial cells for molecular studies . Opens in a new window.
11 September 2003
β-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion
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Rights & permissionsfor article <i>β</i>-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion . Opens in a new window.
13 February 2003
NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers
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Rights & permissionsfor article <i>NORE1A</i>, a homologue of <i>RASSF1A</i> tumour suppressor gene is inactivated in human cancers . Opens in a new window.
16 October 2003
Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer
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Oncogene 22 , 7243–7246

Rights & permissionsfor article Increased expression and no mutation of the <i>Flap endonuclease</i> (<i>FEN1</i>) gene in human lung cancer . Opens in a new window.
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Synthetic lethal screen identification of chemosensitizer loci in cancer cells
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Rights & permissionsfor article Synthetic lethal screen identification of chemosensitizer loci in cancer cells . Opens in a new window.
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Involvement of AGO1 and AGO2 in mammalian transcriptional silencing
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Rights & permissionsfor article Involvement of AGO1 and AGO2 in mammalian transcriptional silencing . Opens in a new window.
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Mutation analysis of the coding sequences of MEK-1 and MEK-2 genes in human lung cancer cell lines
Oncogene 14 , 1231–1234

Rights & permissionsfor article Mutation analysis of the coding sequences of MEK-1 and MEK-2 genes in human lung cancer cell lines . Opens in a new window.
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Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene
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Oncogene 16 , 3151–3157

Rights & permissionsfor article Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene . Opens in a new window.
9 July 2002
The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14^ARF, p16^INK4a and RASSF1A in human lung cancer cell lines
Oncogene 21 , 4822–4829

Rights & permissionsfor article The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of <i>p14</i><sup>ARF</sup>, <i>p16</i><sup>INK4a</sup> and <i>RASSF1A</i> in human lung cancer cell lines . Opens in a new window.

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