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News and Views | 28 June 2001
Glowing switches
- Johannes L. Bos
Nature 411 , 1006–1007

Rights & permissionsfor article Glowing switches . Opens in a new window.
News and Views | 13 May 2004
Thumbs up for inactivation
- Holger Rehmann
- & Johannes L. Bos
Nature 429 , 138–139

Rights & permissionsfor article Thumbs up for inactivation . Opens in a new window.
6 February 1997
Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras
- Johan de Rooij
- & Johannes L Bos
Oncogene 14 , 623–625

Rights & permissionsfor article Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras . Opens in a new window.
News and Views | 26 August 1999
Rhapsody in G proteins
- Johannes L. Bos
- & Fried J. T. Zwartkruis
Nature 400 , 820–821

Rights & permissionsfor article Rhapsody in G proteins . Opens in a new window.
Correspondence | 1 April 2008
Cyclic nucleotide analogs as probes of signaling pathways
- Heiko Poppe
- , Sergei D Rybalkin
- , Holger Rehmann
- , Thomas R Hinds
- , Xiao-Bo Tang
- , Anne E Christensen
- , Frank Schwede
- , Hans-Gottfried Genieser
- , Johannes L Bos
- , Stein O Doskeland
- , Joseph A Beavo
- & Elke Butt
Nature Methods 5 , 277–278

Rights & permissionsfor article Cyclic nucleotide analogs as probes of signaling pathways . Opens in a new window.
News and Views | 1 October 2004
RAPL: taking the Rap in immunity
- Leo S Price
- & Johannes L Bos
Nature Immunology 5 , 1007–1008

Rights & permissionsfor article RAPL: taking the Rap in immunity . Opens in a new window.
Reviews | 16 April 2014
DEP domains: structurally similar but functionally different
Nature Reviews Molecular Cell Biology 15 , 357–362

Rights & permissionsfor article DEP domains: structurally similar but functionally different . Opens in a new window.
Research | 28 May 1987
Prevalence of ras gene mutations in human colorectal cancers
Nature 327 , 293–297

Rights & permissionsfor article Prevalence of ras gene mutations in human colorectal cancers . Opens in a new window.
Reviews | 1 September 2003
Epac: a new cAMP target and new avenues in cAMP research
- Johannes L. Bos
Nature Reviews Molecular Cell Biology 4 , 733–738

Rights & permissionsfor article Epac: a new cAMP target and new avenues in cAMP research . Opens in a new window.
Research | 19 September 2002
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
Nature 419 , 316–321

Rights & permissionsfor article Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress . Opens in a new window.
Research | 18 June 1992
Involvement of p21^ras in activation of extracellular signal-regulated kinase 2
Nature 357 , 602–604

Rights & permissionsfor article Involvement of p21ras in activation of extracellular signal-regulated kinase 2 . Opens in a new window.
Research | 29 September 1994
Activation of p70/p85 S6 kinase by a pathway independent of p21fi ras
Nature 371 , 426–429

Rights & permissionsfor article Activation of p70/p85 S6 kinase by a pathway independent of p21fi ras . Opens in a new window.
Research | 3 December 1998
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP
Nature 396 , 474–477

Rights & permissionsfor article Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP . Opens in a new window.
Research | 28 October 2002
A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK
Nature Cell Biology 4 , 901–906

Rights & permissionsfor article A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK . Opens in a new window.
Research | 15 April 1999
Direct control of the Forkhead transcription factor AFX by protein kinase B
Nature 398 , 630–634

Rights & permissionsfor article Direct control of the Forkhead transcription factor AFX by protein kinase B . Opens in a new window.
14 September 1999
Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and ΔE1B adenovirus replication in human cells
Oncogene 18 , 5032–5043

Rights & permissionsfor article Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and ΔE1B adenovirus replication in human cells . Opens in a new window.
Research | 9 December 2002
Structure and regulation of the cAMP-binding domains of Epac2
- Holger Rehmann
- , Balaji Prakash
- , Eva Wolf
- , Alma Rueppel
- , Johan de Rooij
- , Johannes L. Bos
- & Alfred Wittinghofer
Nature Structural & Molecular Biology 10 , 26–32

Rights & permissionsfor article Structure and regulation of the cAMP-binding domains of Epac2 . Opens in a new window.
Research | 19 December 2010
TSPYL5 suppresses p53 levels and function by physical interaction with USP7
Nature Cell Biology 13 , 102–108

Rights & permissionsfor article TSPYL5 suppresses p53 levels and function by physical interaction with USP7 . Opens in a new window.
Research | 1 June 1985
Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia
Nature 315 , 726–730

Rights & permissionsfor article Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia . Opens in a new window.
Research | 27 July 2008
Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
Nature 455 , 124–127

Rights & permissionsfor article Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B . Opens in a new window.
Research | 13 April 2000
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27^kip1
Nature 404 , 782–787

Rights & permissionsfor article AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1 . Opens in a new window.
4 August 1999
Interdependent action of RalGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells
Oncogene 18 , 4435–4439

Rights & permissionsfor article Interdependent action of RalGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells . Opens in a new window.
31 January 2005
Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP
Oncogene 24 , 2087–2095

Rights & permissionsfor article Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP . Opens in a new window.
26 January 1998
The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells
Oncogene 16 , 349–357

Rights & permissionsfor article The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells . Opens in a new window.
Research | 2 February 2006
Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state
Nature 439 , 625–628

Rights & permissionsfor article Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state . Opens in a new window.
Research | 22 April 2019
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity
Nature Medicine 25 , 838–849

Rights & permissionsfor article An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity . Opens in a new window.
Reviews | 1 May 2001
Rap1 signalling: adhering to new models
Nature Reviews Molecular Cell Biology 2 , 369–377

Rights & permissionsfor article Rap1 signalling: adhering to new models . Opens in a new window.
13 March 1997
Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation
Oncogene 14 , 1147–1157

Rights & permissionsfor article Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation . Opens in a new window.
20 November 1997
Insulin activates Stat3 independently of p21ras-ERK and PI-3K signal transduction
Oncogene 15 , 2529–2539

Rights & permissionsfor article Insulin activates Stat3 independently of p21ras-ERK and PI-3K signal transduction . Opens in a new window.
Reviews | 1 January 2007
Capturing cyclic nucleotides in action: snapshots from crystallographic studies
Nature Reviews Molecular Cell Biology 8 , 63–73

Rights & permissionsfor article Capturing cyclic nucleotides in action: snapshots from crystallographic studies . Opens in a new window.
Research | 15 July 2012
Rap2A links intestinal cell polarity to brush border formation
Nature Cell Biology 14 , 793–801

Rights & permissionsfor article Rap2A links intestinal cell polarity to brush border formation . Opens in a new window.

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Glowing switches

Thumbs up for inactivation

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras

Rhapsody in G proteins

Cyclic nucleotide analogs as probes of signaling pathways

RAPL: taking the Rap in immunity

DEP domains: structurally similar but functionally different

Prevalence of ras gene mutations in human colorectal cancers

Epac: a new cAMP target and new avenues in cAMP research

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

Involvement of p21^ras in activation of extracellular signal-regulated kinase 2

Activation of p70/p85 S6 kinase by a pathway independent of p21fi ras

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK

Direct control of the Forkhead transcription factor AFX by protein kinase B

Infectivity and expression of the early adenovirus proteins are important regulators of wild-type and ΔE1B adenovirus replication in human cells

Structure and regulation of the cAMP-binding domains of Epac2

TSPYL5 suppresses p53 levels and function by physical interaction with USP7

Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27^kip1

Interdependent action of RalGEF and Erk in Ras-induced primitive endoderm differentiation of F9 embryonal carcinoma cells

Activation of FoxO transcription factors contributes to the antiproliferative effect of cAMP

The large E1B protein together with the E4orf6 protein target p53 for active degradation in adenovirus infected cells

Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Rap1 signalling: adhering to new models

Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation

Insulin activates Stat3 independently of p21ras-ERK and PI-3K signal transduction

Capturing cyclic nucleotides in action: snapshots from crystallographic studies

Rap2A links intestinal cell polarity to brush border formation

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