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Research | 28 September 2020
Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesis
- Laila Karra
- , Damia Romero-Moya
- , Olga Ksionda
- , Milana Krush
- , Zhaohui Gu
- , Marsilius Mues
- , Philippe Depeille
- , Charles Mullighan
- & Jeroen P. Roose
Oncogene 39 , 6920–6934

Rights & permissionsfor article Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesis . Opens in a new window.
News and Views | 16 November 2016
Lost GRP on cytotoxicity?
- Jeroen P Roose
Nature Immunology 17 , 1339–1340

Rights & permissionsfor article Lost GRP on cytotoxicity? . Opens in a new window.
Research | 8 August 2016
One-way membrane trafficking of SOS in receptor-triggered Ras activation
- Sune M Christensen
- , Hsiung-Lin Tu
- , Jesse E Jun
- , Steven Alvarez
- , Meredith G Triplet
- , Jeffrey S Iwig
- , Kamlesh K Yadav
- , Dafna Bar-Sagi
- , Jeroen P Roose
- & Jay T Groves
Nature Structural & Molecular Biology 23 , 838–846

Rights & permissionsfor article One-way membrane trafficking of SOS in receptor-triggered Ras activation . Opens in a new window.
Research | 25 May 2015
RasGRP1 opposes proliferative EGFR–SOS1–Ras signals and restricts intestinal epithelial cell growth
- Philippe Depeille
- , Linda M. Henricks
- , Robert A. H. van de Ven
- , Ed Lemmens
- , Chih-Yang Wang
- , Mary Matli
- , Zena Werb
- , Kevin M. Haigis
- , David Donner
- , Robert Warren
- & Jeroen P. Roose
Nature Cell Biology 17 , 804–815

Rights & permissionsfor article RasGRP1 opposes proliferative EGFR–SOS1–Ras signals and restricts intestinal epithelial cell growth . Opens in a new window.
Research | 27 March 2011
STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development
- Andre Limnander
- , Philippe Depeille
- , Tanya S Freedman
- , Jen Liou
- , Michael Leitges
- , Tomohiro Kurosaki
- , Jeroen P Roose
- & Arthur Weiss
Nature Immunology 12 , 425–433

Rights & permissionsfor article STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development . Opens in a new window.
Research | 2 September 2009
Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras
- Jennifer O. Lauchle
- , Doris Kim
- , Doan T. Le
- , Keiko Akagi
- , Michael Crone
- , Kimberly Krisman
- , Kegan Warner
- , Jeannette M. Bonifas
- , Qing Li
- , Kristen M. Coakley
- , Ernesto Diaz-Flores
- , Matthew Gorman
- , Sally Przybranowski
- , Mary Tran
- , Scott C. Kogan
- , Jeroen P. Roose
- , Neal G. Copeland
- , Nancy A. Jenkins
- , Luis Parada
- , Linda Wolff
- , Judith Sebolt-Leopold
- & Kevin Shannon
Nature 461 , 411–414

Rights & permissionsfor article Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras . Opens in a new window.

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Increased baseline RASGRP1 signals enhance stem cell fitness during native hematopoiesis

Lost GRP on cytotoxicity?

One-way membrane trafficking of SOS in receptor-triggered Ras activation

RasGRP1 opposes proliferative EGFR–SOS1–Ras signals and restricts intestinal epithelial cell growth

STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development

Response and resistance to MEK inhibition in leukaemias initiated by hyperactive Ras

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