Showing 1–14 of 14 results
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Research | | Open
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Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
- Gabriela S. Kinker
- , Alissa C. Greenwald
- , Rotem Tal
- , Zhanna Orlova
- , Michael S. Cuoco
- , James M. McFarland
- , Allison Warren
- , Christopher Rodman
- , Jennifer A. Roth
- , Samantha A. Bender
- , Bhavna Kumar
- , James W. Rocco
- , Pedro A. C. M. Fernandes
- , Christopher C. Mader
- , Hadas Keren-Shaul
- , Alexander Plotnikov
- , Haim Barr
- , Aviad Tsherniak
- , Orit Rozenblatt-Rosen
- , Valery Krizhanovsky
- , Sidharth V. Puram
- , Aviv Regev
- & Itay Tirosh
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Research | | Open
Multiplexed single-cell transcriptional response profiling to define cancer vulnerabilities and therapeutic mechanism of action
- James M. McFarland
- , Brenton R. Paolella
- , Allison Warren
- , Kathryn Geiger-Schuller
- , Tsukasa Shibue
- , Michael Rothberg
- , Olena Kuksenko
- , William N. Colgan
- , Andrew Jones
- , Emily Chambers
- , Danielle Dionne
- , Samantha Bender
- , Brian M. Wolpin
- , Mahmoud Ghandi
- , Itay Tirosh
- , Orit Rozenblatt-Rosen
- , Jennifer A. Roth
- , Todd R. Golub
- , Aviv Regev
- , Andrew J. Aguirre
- , Francisca Vazquez
- & Aviad Tsherniak
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Discovering the anticancer potential of non-oncology drugs by systematic viability profiling
- Steven M. Corsello
- , Rohith T. Nagari
- , Ryan D. Spangler
- , Jordan Rossen
- , Mustafa Kocak
- , Jordan G. Bryan
- , Ranad Humeidi
- , David Peck
- , Xiaoyun Wu
- , Andrew A. Tang
- , Vickie M. Wang
- , Samantha A. Bender
- , Evan Lemire
- , Rajiv Narayan
- , Philip Montgomery
- , Uri Ben-David
- , Colin W. Garvie
- , Yejia Chen
- , Matthew G. Rees
- , Nicholas J. Lyons
- , James M. McFarland
- , Bang T. Wong
- , Li Wang
- , Nancy Dumont
- , Patrick J. O’Hearn
- , Eric Stefan
- , John G. Doench
- , Caitlin N. Harrington
- , Heidi Greulich
- , Matthew Meyerson
- , Francisca Vazquez
- , Aravind Subramanian
- , Jennifer A. Roth
- , Joshua A. Bittker
- , Jesse S. Boehm
- , Christopher C. Mader
- , Aviad Tsherniak
- & Todd R. Golub
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Next-generation characterization of the Cancer Cell Line Encyclopedia
- Mahmoud Ghandi
- , Franklin W. Huang
- , Judit Jané-Valbuena
- , Gregory V. Kryukov
- , Christopher C. Lo
- , E. Robert McDonald III
- , Jordi Barretina
- , Ellen T. Gelfand
- , Craig M. Bielski
- , Haoxin Li
- , Kevin Hu
- , Alexander Y. Andreev-Drakhlin
- , Jaegil Kim
- , Julian M. Hess
- , Brian J. Haas
- , François Aguet
- , Barbara A. Weir
- , Michael V. Rothberg
- , Brenton R. Paolella
- , Michael S. Lawrence
- , Rehan Akbani
- , Yiling Lu
- , Hong L. Tiv
- , Prafulla C. Gokhale
- , Antoine de Weck
- , Ali Amin Mansour
- , Coyin Oh
- , Juliann Shih
- , Kevin Hadi
- , Yanay Rosen
- , Jonathan Bistline
- , Kavitha Venkatesan
- , Anupama Reddy
- , Dmitriy Sonkin
- , Manway Liu
- , Joseph Lehar
- , Joshua M. Korn
- , Dale A. Porter
- , Michael D. Jones
- , Javad Golji
- , Giordano Caponigro
- , Jordan E. Taylor
- , Caitlin M. Dunning
- , Amanda L. Creech
- , Allison C. Warren
- , James M. McFarland
- , Mahdi Zamanighomi
- , Audrey Kauffmann
- , Nicolas Stransky
- , Marcin Imielinski
- , Yosef E. Maruvka
- , Andrew D. Cherniack
- , Aviad Tsherniak
- , Francisca Vazquez
- , Jacob D. Jaffe
- , Andrew A. Lane
- , David M. Weinstock
- , Cory M. Johannessen
- , Michael P. Morrissey
- , Frank Stegmeier
- , Robert Schlegel
- , William C. Hahn
- , Gad Getz
- , Gordon B. Mills
- , Jesse S. Boehm
- , Todd R. Golub
- , Levi A. Garraway
- & William R. Sellers
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WRN helicase is a synthetic lethal target in microsatellite unstable cancers
- Edmond M. Chan
- , Tsukasa Shibue
- , James M. McFarland
- , Benjamin Gaeta
- , Mahmoud Ghandi
- , Nancy Dumont
- , Alfredo Gonzalez
- , Justine S. McPartlan
- , Tianxia Li
- , Yanxi Zhang
- , Jie Bin Liu
- , Jean-Bernard Lazaro
- , Peili Gu
- , Cortt G. Piett
- , Annie Apffel
- , Syed O. Ali
- , Rebecca Deasy
- , Paula Keskula
- , Raymond W. S. Ng
- , Emma A. Roberts
- , Elizaveta Reznichenko
- , Lisa Leung
- , Maria Alimova
- , Monica Schenone
- , Mirazul Islam
- , Yosef E. Maruvka
- , Yang Liu
- , Jatin Roper
- , Srivatsan Raghavan
- , Marios Giannakis
- , Yuen-Yi Tseng
- , Zachary D. Nagel
- , Alan D’Andrea
- , David E. Root
- , Jesse S. Boehm
- , Gad Getz
- , Sandy Chang
- , Todd R. Golub
- , Aviad Tsherniak
- , Francisca Vazquez
- & Adam J. Bass
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Mutational processes shape the landscape of TP53 mutations in human cancer
- Andrew O. Giacomelli
- , Xiaoping Yang
- , Robert E. Lintner
- , James M. McFarland
- , Marc Duby
- , Jaegil Kim
- , Thomas P. Howard
- , David Y. Takeda
- , Seav Huong Ly
- , Eejung Kim
- , Hugh S. Gannon
- , Brian Hurhula
- , Ted Sharpe
- , Amy Goodale
- , Briana Fritchman
- , Scott Steelman
- , Francisca Vazquez
- , Aviad Tsherniak
- , Andrew J. Aguirre
- , John G. Doench
- , Federica Piccioni
- , Charles W. M. Roberts
- , Matthew Meyerson
- , Gad Getz
- , Cory M. Johannessen
- , David E. Root
- & William C. Hahn
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Research | | Open
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Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
- Robin M Meyers
- , Jordan G Bryan
- , James M McFarland
- , Barbara A Weir
- , Ann E Sizemore
- , Han Xu
- , Neekesh V Dharia
- , Phillip G Montgomery
- , Glenn S Cowley
- , Sasha Pantel
- , Amy Goodale
- , Yenarae Lee
- , Levi D Ali
- , Guozhi Jiang
- , Rakela Lubonja
- , William F Harrington
- , Matthew Strickland
- , Ting Wu
- , Derek C Hawes
- , Victor A Zhivich
- , Meghan R Wyatt
- , Zohra Kalani
- , Jaime J Chang
- , Michael Okamoto
- , Kimberly Stegmaier
- , Todd R Golub
- , Jesse S Boehm
- , Francisca Vazquez
- , David E Root
- , William C Hahn
- & Aviad Tsherniak
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