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Research | 24 November 2020 | Open
The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain
- María José Iglesias
- , Daniel Ibarz
- , Alberto Cebollada
- , Jéssica Comín
- , María Soledad Jiménez
- , María C. Vázquez
- , Sofía Samper
- , T. Cabezas
- , A. Reyes
- , I. Ruiz
- , P. García
- , M. D. López
- , L. Cardeñoso
- , I. Jesús de la Calle
- , P. Ruiz
- , J. C. Alados
- , J. Román
- , R. Villa-Real
- , J. Saavedra
- , C. Amores
- , P. Bermúdez
- , M. A. Sánchez
- , N. Montiel
- , S. Bernal
- , J. A. Lepe
- , N. Batista
- , E. Roldán
- , L. Torres
- , C. Navarro
- , P. Chocarro
- , M. J. Aldea
- , J. Viñuelas
- , M. A. Vitoria
- , J. J. Palacios
- , H. Villar
- , P. Prendes
- , M. Blanco
- , F. Vázquez
- , M. Telenti
- , I. Sánchez
- , L. Carbo
- , S. Escobar
- , A. Ramírez
- , C. Gallegos
- , M. C. Pérez
- , M. Lecuona
- , O. Díez
- , R. Copado
- , I. Campos
- , F. Cañas
- , C. Salas
- , C. Fernández
- , M. P. Roíz
- , I. Barba
- , E. Manrique
- , R. Carranza
- , A. Sánchez Maroto
- , A. González
- , E. Rodríguez
- , V. Martino
- , C. Sánchez
- , C. Martínez
- , P. Robles
- , E. Simarro
- , C. Romero
- , R. López
- , M. D. Blanco
- , T. Nebreda
- , J. Rodríguez
- , J. M. Fernández
- , E. Álvarez
- , M. L. Jaime
- , M. D. Tejero
- , A. Alberte
- , E. Oteda
- , G. Megías
- , C. Labayru
- , R. Ibáñez
- , A. Campos
- , P. Carrero
- , J. M. Villó
- , T. Sans
- , I. Pujol
- , X. Clivillé
- , J. B. Castellví
- , J. de Batlle
- , D. Mariscal
- , C. Prat
- , M. García
- , F. Alcalde
- , C. Gallén
- , G. Sauca
- , E. Cuchi
- , C. Alonso
- , F. Corcoy
- , G. Schmidt
- , M. T. Tortola
- , E. Garduño
- , J. J. Moreno
- , P. Hernández
- , I. Montes
- , J. Roman
- , P. Alonso
- , A. Rodríguez
- , L. Barbeyto
- , B. Fernández
- , D. Domínguez
- , R. Villanueva
- , I. Iglesias
- , F. J. Vasallo
- , J. Sevillano
- , A. Pascual
- , M. García
- , M. L. Pérez del Molino
- , V. Martino
- , E. Ugalde
- , R. Dopereiro
- , J. A. Cuadros
- , I. Pelayo
- , J. Cacho
- , R. Cogollos
- , M. Páez
- , S. Prieto
- , R. Fernández
- , P. López
- , D. Domingo
- , R. Millán
- , I. Bonilla
- , P. Merino
- , C. Toro
- , M. J. Ruiz
- , M. Menéndez
- , P. Romero
- , M. Tato
- , M. Simón
- , A. Urmeneta
- , A. Delgado
- , L. García
- , J. Cobos
- , J. Merino
- , E. Aznar
- , J. Piqueras
- , M. D. Navarro
- , J. M. Artero
- , A. Navascués
- , A. Gil
- , J. Leiva
- , L. Elorduy
- , E. Urra
- , P. Idígoras
- , E. Pérez-Trallero
- , A. Canut
- , J. L. Barrios
- , L. Michans
- , R. Ayarza
- , F. García
- , M. J. Unzaga
- , M. Navarro
- , N. Gonzalo
- , C. Martín
- , C. Martínez
- , A. Gimeno
- , M. Elia
- , P. López
- , S. Sabater
- , J. C. Rodríguez
- , M. Santos
- , M. Bosque
- , J. López
- , E. Tabernero
- & M. I. Galán
Scientific Reports 10 , 1–12

Rights & permissionsfor article The value of the continuous genotyping of multi-drug resistant tuberculosis over 20 years in Spain . Opens in a new window.
Amendments and Corrections | 6 January 2020
Publisher Correction: Directed evolution improves the catalytic efficiency of TEV protease
- Mateo I. Sanchez
- & Alice Y. Ting
Nature Methods 17 , 242–242

Rights & permissionsfor article Publisher Correction: Directed evolution improves the catalytic efficiency of TEV protease . Opens in a new window.
Amendments and Corrections | 15 May 2018 | Open
Author Correction: White Matter and Gray Matter Segmentation in 4D Computed Tomography
Scientific Reports 8 , 1–1

Rights & permissionsfor article Author Correction: White Matter and Gray Matter Segmentation in 4D Computed Tomography . Opens in a new window.
Research | 10 September 2020 | Open
Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against Burkholderia mallei
npj Vaccines 5 , 1–11

Rights & permissionsfor article Multicomponent gold nano-glycoconjugate as a highly immunogenic and protective platform against <i>Burkholderia mallei</i> . Opens in a new window.
1 June 1999
A preeclampsia model by chronic NOS inhibition in pregnant rats affects endothelium-dependent relaxation in fetal but not in newborn rats
- J Martínez-Orgado
- , J Marín
- , R González
- , I Sánchez-Vera
- , M Salaices
- , B Bonet
- & M J Alonso
Pediatric Research 45 , 898–898

Rights & permissionsfor article A preeclampsia model by chronic NOS inhibition in pregnant rats affects endothelium-dependent relaxation in fetal but not in newborn rats . Opens in a new window.
Research | 29 April 2019 | Open
Genetic risk score has added value over initial clinical grading stage in predicting disease progression in age-related macular degeneration
Scientific Reports 9 , 1–8

Rights & permissionsfor article Genetic risk score has added value over initial clinical grading stage in predicting disease progression in age-related macular degeneration . Opens in a new window.
Research | 13 February 2018
Advantages of non-cryopreserved autologous hematopoietic stem cell transplantation against a cryopreserved strategy
- M. Sarmiento
- , P. Ramírez
- , R. Parody
- , MQ. Salas
- , N. Beffermann
- , V. Jara
- , P. Bertín
- , I. Pizarro
- , C. Lorca
- , E. Rivera
- , M. Galleguillos
- , M. Ocqueteau
- , I. Sánchez-Ortega
- , B. Patiño
- & A. Sureda
Bone Marrow Transplantation 53 , 960–966

Rights & permissionsfor article Advantages of non-cryopreserved autologous hematopoietic stem cell transplantation against a cryopreserved strategy . Opens in a new window.
31 October 2016
Serum galactomannan surveillance may be safely withdrawn from antifungal management of hematology patients on effective antimold prophylaxis: a pilot single-center study
- R F Duarte
- , I Sánchez-Ortega
- , M Arnan
- , B Patiño
- , J Ayats
- , A Sureda
- & M Cuenca-Estrella
Bone Marrow Transplantation 52 , 326–329

Rights & permissionsfor article Serum galactomannan surveillance may be safely withdrawn from antifungal management of hematology patients on effective antimold prophylaxis: a pilot single-center study . Opens in a new window.
Research | 29 April 2016 | Open
An automated tuberculosis screening strategy combining X-ray-based computer-aided detection and clinical information
Scientific Reports 6 , 1–8

Rights & permissionsfor article An automated tuberculosis screening strategy combining X-ray-based computer-aided detection and clinical information . Opens in a new window.
Research | 23 May 2016 | Open
Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis
Scientific Reports 6 , 1–11

Rights & permissionsfor article Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis . Opens in a new window.
Research | 27 March 2017
Haplo-Cord transplantation compared to haploidentical transplantation with post-transplant cyclophosphamide in patients with AML
- M Kwon
- , G Bautista
- , P Balsalobre
- , I Sánchez-Ortega
- , P Montesinos
- , A Bermúdez
- , A de Laiglesia
- , P Herrera
- , C Martin
- , K Humala
- , A Zabalza
- , M Torres
- , L Bento
- , L L Corral
- , I Heras
- , D Serrano
- , I Buño
- , J Anguita
- , C Regidor
- , R Duarte
- , R Cabrera
- , J Gayoso
- & J L Diez-Martin
Bone Marrow Transplantation 52 , 1138–1143

Rights & permissionsfor article Haplo-Cord transplantation compared to haploidentical transplantation with post-transplant cyclophosphamide in patients with AML . Opens in a new window.
Research | 26 February 2020 | Open
MitoBlue as a tool to analyze the mitochondria-lysosome communication
Scientific Reports 10 , 1–12

Rights & permissionsfor article MitoBlue as a tool to analyze the mitochondria-lysosome communication . Opens in a new window.
Research | 27 July 2015 | Open
Automated chest-radiography as a triage for Xpert testing in resource-constrained settings: a prospective study of diagnostic accuracy and costs
- R. H. H. M. Philipsen
- , C. I. Sánchez
- , P. Maduskar
- , J. Melendez
- , L. Peters-Bax
- , J. G. Peter
- , R. Dawson
- , G. Theron
- , K. Dheda
- & B. van Ginneken
Scientific Reports 5 , 1–8

Rights & permissionsfor article Automated chest-radiography as a triage for Xpert testing in resource-constrained settings: a prospective study of diagnostic accuracy and costs . Opens in a new window.
Research | 15 September 2014
Plerixafor in patients with lymphoma and multiple myeloma: effectiveness in cases with very low circulating CD34+ cell levels and preemptive intervention vs remobilization
- I Sánchez-Ortega
- , S Querol
- , M Encuentra
- , S Ortega
- , A Serra
- , J M Sanchez-Villegas
- , J R Grifols
- , M M Pujol-Balaguer
- , M Pujol-Bosch
- , J M Martí
- , T Garcia-Cerecedo
- , P Barba
- , J M Sancho
- , A Esquirol
- , J Sierra
- & R F Duarte
Bone Marrow Transplantation 50 , 34–39

Rights & permissionsfor article Plerixafor in patients with lymphoma and multiple myeloma: effectiveness in cases with very low circulating CD34+ cell levels and preemptive intervention vs remobilization . Opens in a new window.
Research | 11 June 2014
Picometre-precision analysis of scanning transmission electron microscopy images of platinum nanocatalysts
- Andrew B. Yankovich
- , Benjamin Berkels
- , W. Dahmen
- , P. Binev
- , S. I. Sanchez
- , S. A. Bradley
- , Ao Li
- , Izabela Szlufarska
- & Paul M. Voyles
Nature Communications 5 , 1–7

Rights & permissionsfor article Picometre-precision analysis of scanning transmission electron microscopy images of platinum nanocatalysts . Opens in a new window.
12 August 2013
Early engraftment and full-donor chimerism after single-cord blood plus third-party donor dual transplantation in patients with high-risk acute leukemia
- I Sánchez-Ortega
- , M Arnan
- , B Patiño
- , M J Herrero
- , S Querol
- & R F Duarte
Bone Marrow Transplantation 49 , 145–147

Rights & permissionsfor article Early engraftment and full-donor chimerism after single-cord blood plus third-party donor dual transplantation in patients with high-risk acute leukemia . Opens in a new window.
Research | 24 March 2014
Etiology, clinical features and outcomes of pre-engraftment and post-engraftment bloodstream infection in hematopoietic SCT recipients
- C Gudiol
- , C Garcia-Vidal
- , M Arnan
- , I Sánchez-Ortega
- , B Patiño
- , R Duarte
- & J Carratalà
Bone Marrow Transplantation 49 , 824–830

Rights & permissionsfor article Etiology, clinical features and outcomes of pre-engraftment and post-engraftment bloodstream infection in hematopoietic SCT recipients . Opens in a new window.
Research | 24 January 2020 | Open
Single-cell analysis reveals new evolutionary complexity in uveal melanoma
Nature Communications 11 , 1–10

Rights & permissionsfor article Single-cell analysis reveals new evolutionary complexity in uveal melanoma . Opens in a new window.
1 July 2009
Malacoplakia presenting with obstructive nephropathy with bilateral ureter involvement
Nature Reviews Nephrology 5 , 418–422

Rights & permissionsfor article Malacoplakia presenting with obstructive nephropathy with bilateral ureter involvement . Opens in a new window.
Research | 1 July 2001
Sperm development, age and sex chromosome meiotic drive in the stalk-eyed fly, Cyrtodiopsis whitei
- Gerald S Wilkinson
- & Mara I Sanchez
Heredity 87 , 17–24

Rights & permissionsfor article Sperm development, age and sex chromosome meiotic drive in the stalk-eyed fly, <i>Cyrtodiopsis whitei</i> . Opens in a new window.
8 January 2008 | Open
Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2)
British Journal of Cancer 98 , 480–488

Rights & permissionsfor article Transcriptomal profiling of the cellular response to DNA damage mediated by Slug (Snai2) . Opens in a new window.
1 January 2000
CFTR Mutations in Chilean patients with cystic fibrosis
- G M Repetto
- , I Flores
- , C Lobo
- , M L Boza
- , M A Perez
- , E Guiraldes
- , P Harris
- & I Sanchez
Genetics in Medicine 2 , 106–106

Rights & permissionsfor article CFTR Mutations in Chilean patients with cystic fibrosis . Opens in a new window.
21 March 2011
Thyroid dysfunction in adult patients late after autologous and allogeneic blood and marrow transplantation
- I Sánchez-Ortega
- , C Canals
- , T Peralta
- , R Parody
- , V Clapés
- , A F de Sevilla
- & R F Duarte
Bone Marrow Transplantation 47 , 296–298

Rights & permissionsfor article Thyroid dysfunction in adult patients late after autologous and allogeneic blood and marrow transplantation . Opens in a new window.
Research | 11 July 2001
Administration of post-autologous PBSCT rhG-CSF is associated with long-term low concentrations of bone marrow hematopoietic progenitor cells
- MM Osma
- , F Ortuño
- , ML Lozano
- , J Gomez-Espuch
- , F Ayala
- , I Sanchez-Serrano
- , E Perez-Ceballos
- , JM Moraleda
- & V Vicente
Bone Marrow Transplantation 27 , 1287–1292

Rights & permissionsfor article Administration of post-autologous PBSCT rhG-CSF is associated with long-term low concentrations of bone marrow hematopoietic progenitor cells . Opens in a new window.
Research | 9 August 2010
Clinical efficacy and safety of primary antifungal prophylaxis with posaconazole vs itraconazole in allogeneic blood and marrow transplantation
- I Sánchez-Ortega
- , B Patiño
- , M Arnan
- , T Peralta
- , R Parody
- , C Gudiol
- , M Encuentra
- , A Fernández de Sevilla
- & R F Duarte
Bone Marrow Transplantation 46 , 733–739

Rights & permissionsfor article Clinical efficacy and safety of primary antifungal prophylaxis with posaconazole vs itraconazole in allogeneic blood and marrow transplantation . Opens in a new window.
5 March 2012
Reply to SB Mossad
Bone Marrow Transplantation 47 , 1380–1380

Rights & permissionsfor article Reply to SB Mossad . Opens in a new window.
23 May 2000
The chimeric FUS/TLS-CHOP fusion protein specifically induces liposarcomas in transgenic mice
- J Pérez-Losada
- , B Pintado
- , A Gutiérrez-Adán
- , T Flores
- , B Bañares-González
- , J Calabia del Campo
- , J F Martín-Martín
- , E Battaner
- & I Sánchez-García
Oncogene 19 , 2413–2422

Rights & permissionsfor article The chimeric FUS/TLS-CHOP fusion protein specifically induces liposarcomas in transgenic mice . Opens in a new window.
Reviews | 3 February 2004 | Open
Control of oncogenesis and cancer therapy resistance
- R Perona
- & I Sánchez-Pérez
British Journal of Cancer 90 , 573–577

Rights & permissionsfor article Control of oncogenesis and cancer therapy resistance . Opens in a new window.
Research | 25 June 2010
Negative plant–soil feedback predicts tree-species relative abundance in a tropical forest
Nature 466 , 752–755

Rights & permissionsfor article Negative plant–soil feedback predicts tree-species relative abundance in a tropical forest . Opens in a new window.
Correspondence | 10 March 1999
Immunoglobulin lambda chain gene rearrangement in a case of acute nonlymphoblastic leukemia
Leukemia 13 , 485–487

Rights & permissionsfor article Immunoglobulin lambda chain gene rearrangement in a case of acute nonlymphoblastic leukemia . Opens in a new window.
7 December 2000
Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma
- J Pérez-Losada
- , M Sánchez-Martín
- , M A Rodríguez-García
- , P A Pérez-Mancera
- , B Pintado
- , T Flores
- , E Battaner
- & I Sánchez-García
Oncogene 19 , 6015–6022

Rights & permissionsfor article Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma . Opens in a new window.
News and Views | 28 January 2011 | Open
Research recommendations toward a better understanding of the causes of childhood leukemia
- G Ziegelberger
- , C Baum
- , A Borkhardt
- , C Cobaleda
- , C Dasenbrock
- , A Dehos
- , B Grosche
- , J Hauer
- , S Hornhardt
- , T Jung
- , T Kammertoens
- , I Lagroye
- , H Lehrach
- , T Lightfoot
- , M P Little
- , C Rossig
- , I Sanchez-Garcia
- , M Schrappe
- , J Schuez
- , S Shalapour
- , R Slany
- , M Stanulla
- & W Weiss
Blood Cancer Journal 1 , e1–e1

Rights & permissionsfor article Research recommendations toward a better understanding of the causes of childhood leukemia . Opens in a new window.
Research | 9 December 2019
Directed evolution improves the catalytic efficiency of TEV protease
- Mateo I. Sanchez
- & Alice Y. Ting
Nature Methods 17 , 167–174

Rights & permissionsfor article Directed evolution improves the catalytic efficiency of TEV protease . Opens in a new window.
Research | 6 January 2020 | Open
LncRNA RP11-19E11 is an E2F1 target required for proliferation and survival of basal breast cancer
- A. Giro-Perafita
- , L. Luo
- , A. Khodadadi-Jamayran
- , M. Thompson
- , B. Akgol Oksuz
- , A. Tsirigos
- , B. D. Dynlacht
- , I. Sánchez
- & F. J. Esteva
npj Breast Cancer 6 , 1–14

Rights & permissionsfor article LncRNA RP11-19E11 is an E2F1 target required for proliferation and survival of basal breast cancer . Opens in a new window.
Research | 26 June 2017
A light- and calcium-gated transcription factor for imaging and manipulating activated neurons
- Wenjing Wang
- , Craig P Wildes
- , Tanyaporn Pattarabanjird
- , Mateo I Sanchez
- , Gordon F Glober
- , Gillian A Matthews
- , Kay M Tye
- & Alice Y Ting
Nature Biotechnology 35 , 864–871

Rights & permissionsfor article A light- and calcium-gated transcription factor for imaging and manipulating activated neurons . Opens in a new window.
Research | 11 July 2017 | Open
Location Sensitive Deep Convolutional Neural Networks for Segmentation of White Matter Hyperintensities
Scientific Reports 7 , 1–12

Rights & permissionsfor article Location Sensitive Deep Convolutional Neural Networks for Segmentation of White Matter Hyperintensities . Opens in a new window.
Research | 9 March 2017 | Open
White Matter and Gray Matter Segmentation in 4D Computed Tomography
Scientific Reports 7 , 1–11

Rights & permissionsfor article White Matter and Gray Matter Segmentation in 4D Computed Tomography . Opens in a new window.
Research | 12 February 2016 | Open
CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response
Scientific Reports 6 , 1–12

Rights & permissionsfor article CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response . Opens in a new window.
Protocols | 25 July 2013
Site-specific protein labeling using PRIME and chelation-assisted click chemistry
- Chayasith Uttamapinant
- , Mateo I Sanchez
- , Daniel S Liu
- , Jennifer Z Yao
- , Katharine A White
- , Scott Grecian
- , Scott Clark
- , Kyle R Gee
- & Alice Y Ting
Nature Protocols 8 , 1620–1634

Rights & permissionsfor article Site-specific protein labeling using PRIME and chelation-assisted click chemistry . Opens in a new window.
Research | 27 October 2014
Fungal and viral infections after allogeneic hematopoietic transplantation from unrelated donors in adults: improving outcomes over time
- R Parody
- , R Martino
- , R de la Cámara
- , A García-Noblejas
- , A Esquirol
- , I Garcia-Cadenas
- , T Villaescusa
- , D Caballero
- , M Rovira
- , F Fernandez-Avilés
- , F J Marquez-Malaver
- , I Espigado
- , C Castilla-Llorente
- , I Heras
- , M A Cabero
- , J R Cabrera
- , P Barba
- , D Valcarcel
- , I Sánchez-Ortega
- , R F Duarte
- , D Serrano
- , F Carretero
- & L Vazquez
Bone Marrow Transplantation 50 , 274–281

Rights & permissionsfor article Fungal and viral infections after allogeneic hematopoietic transplantation from unrelated donors in adults: improving outcomes over time . Opens in a new window.
Research | 4 April 2013 | Open
GSK-3β signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition
- E Gavilán
- , I Sánchez-Aguayo
- , P Daza
- & D Ruano
Cell Death & Disease 4 , e572–e572

Rights & permissionsfor article GSK-3<i>β</i> signaling determines autophagy activation in the breast tumor cell line MCF7 and inclusion formation in the non-tumor cell line MCF10A in response to proteasome inhibition . Opens in a new window.
Research | 4 October 2010
DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer
- V Moncho-Amor
- , I Ibañez de Cáceres
- , E Bandres
- , B Martínez-Poveda
- , J L Orgaz
- , I Sánchez-Pérez
- , S Zazo
- , A Rovira
- , J Albanell
- , B Jiménez
- , F Rojo
- , C Belda-Iniesta
- , J García-Foncillas
- & R Perona
Oncogene 30 , 668–678

Rights & permissionsfor article DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer . Opens in a new window.
Research | 18 September 2006
Sustained leukaemic phenotype after inactivation of BCR-ABLp190 in mice
- M Pérez-Caro
- , N Gutierrez-Cianca
- , I González-Herrero
- , I López-Hernández
- , T Flores
- , A Orfao
- , M Sánchez-Martín
- , A Gutiérrez-Adán
- , B Pintado
- & I Sánchez-García
Oncogene 26 , 1702–1713

Rights & permissionsfor article Sustained leukaemic phenotype after inactivation of <i>BCR-ABLp190</i> in mice . Opens in a new window.
4 June 2010
p22^phox-dependent NADPH oxidase activity is required for megakaryocytic differentiation
- J L Sardina
- , G López-Ruano
- , L I Sánchez-Abarca
- , J A Pérez-Simón
- , A Gaztelumendi
- , C Trigueros
- , M Llanillo
- , J Sánchez-Yagüe
- & A Hernández-Hernández
Cell Death and Differentiation 17 , 1842–1854

Rights & permissionsfor article p22<sup>phox</sup>-dependent NADPH oxidase activity is required for megakaryocytic differentiation . Opens in a new window.

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