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Research | 4 January 2021 | Open
Dust arriving in the Amazon basin over the past 7,500 years came from diverse sources
Communications Earth & Environment 2 , 1–11

Rights & permissionsfor article Dust arriving in the Amazon basin over the past 7,500 years came from diverse sources . Opens in a new window.
News and Views | 9 November 2017
Shrink-wrapping water to conduct protons
- George K. H. Shimizu
Nature Energy 2 , 842–843

Rights & permissionsfor article Shrink-wrapping water to conduct protons . Opens in a new window.
Research | 7 March 2016 | Open
Transgenic mice overexpressing nesfatin/nucleobindin-2 are susceptible to high-fat diet-induced obesity
- H Shimizu
- , M Tanaka
- & A Osaki
Nutrition & Diabetes 6 , e201–e201

Rights & permissionsfor article Transgenic mice overexpressing nesfatin/nucleobindin-2 are susceptible to high-fat diet-induced obesity . Opens in a new window.
Research | 6 October 2015
Local and systemic responses following intravitreous injection of AAV2-encoded modified Volvox channelrhodopsin-1 in a genetically blind rat model
- E Sugano
- , K Tabata
- , M Takahashi
- , F Nishiyama
- , H Shimizu
- , M Sato
- , M Tamai
- & H Tomita
Gene Therapy 23 , 158–166

Rights & permissionsfor article Local and systemic responses following intravitreous injection of AAV2-encoded modified <i>Volvox</i> channelrhodopsin-1 in a genetically blind rat model . Opens in a new window.
16 June 2003
Two-step association analyses of the chromosome 18p11.2 region in schizophrenia detect a locus encompassing C18orf1
- M Kikuchi
- , K Yamada
- , T Toyota
- , M Itokawa
- , E Hattori
- , K Yoshitsugu
- , H Shimizu
- & T Yoshikawa
Molecular Psychiatry 8 , 467–469

Rights & permissionsfor article Two-step association analyses of the chromosome 18p11.2 region in schizophrenia detect a locus encompassing <i>C18orf1</i> . Opens in a new window.
30 August 2001
Soy product intake and premenopausal hysterectomy in a follow-up study of Japanese women
- C Nagata
- , N Takatsuka
- , N Kawakami
- & H Shimizu
European Journal of Clinical Nutrition 55 , 773–777

Rights & permissionsfor article Soy product intake and premenopausal hysterectomy in a follow-up study of Japanese women . Opens in a new window.
Research | 18 October 2009
Anhydrous proton conduction at 150 °C in a crystalline metal–organic framework
Nature Chemistry 1 , 705–710

Rights & permissionsfor article Anhydrous proton conduction at 150 °C in a crystalline metal–organic framework . Opens in a new window.
17 April 2001
Evidence for association of the myo-inositol monophosphatase 2 (IMPA2) gene with schizophrenia in Japanese samples
- T Yoshikawa
- , M Kikuchi
- , K Saito
- , A Watanabe
- , K Yamada
- , H Shibuya
- , M Nankai
- , A Kurumaji
- , E Hattori
- , H Ishiguro
- , H Shimizu
- , Y Okubo
- , M Toru
- & S D Detera-Wadleigh
Molecular Psychiatry 6 , 202–210

Rights & permissionsfor article Evidence for association of the <i>myo</i>-inositol monophosphatase 2 (<i>IMPA2</i>) gene with schizophrenia in Japanese samples . Opens in a new window.
Research | 13 June 2012
Allogeneic hematopoietic stem cell transplantation for adult AML patients with granulocytic sarcoma
- H Shimizu
- , T Saitoh
- , M Tanaka
- , T Mori
- , T Sakura
- , N Kawai
- , Y Kanda
- , C Nakaseko
- , S Yano
- , H Fujita
- , S Fujisawa
- , S Miyawaki
- , H Kanamori
- & S Okamoto
Leukemia 26 , 2469–2473

Rights & permissionsfor article Allogeneic hematopoietic stem cell transplantation for adult AML patients with granulocytic sarcoma . Opens in a new window.
1 June 1996
Decreased serum retinol levels in women with cervical dysplasia
- H Shimizu
- , C Nagata
- , S Komatsu
- , N Morita
- , H Higashiiwai
- , N Sugahara
- & S Hisamichi
British Journal of Cancer 73 , 1600–1604

Rights & permissionsfor article Decreased serum retinol levels in women with cervical dysplasia . Opens in a new window.
Research | 14 May 1987
Combined La–Ce and Sm–Nd isotope systematics in petrogenetic studies
- T. Tanaka
- , H. Shimizu
- , Y. Kawata
- & A. Masuda
Nature 327 , 113–117

Rights & permissionsfor article Combined La–Ce and Sm–Nd isotope systematics in petrogenetic studies . Opens in a new window.
7 April 2005
Promoter region polymorphism of macrophage migration inhibitory factor is strong risk factor for young onset of extensive alopecia areata
- T Shimizu
- , N Hizawa
- , A Honda
- , Y Zhao
- , R Abe
- , H Watanabe
- , J Nishihira
- , M Nishimura
- & H Shimizu
Genes and Immunity 6 , 285–289

Rights & permissionsfor article Promoter region polymorphism of macrophage migration inhibitory factor is strong risk factor for young onset of extensive alopecia areata . Opens in a new window.
1 September 2004
Associations of menstrual pain with intakes of soy, fat and dietary fiber in Japanese women
- C Nagata
- , K Hirokawa
- , N Shimizu
- & H Shimizu
European Journal of Clinical Nutrition 59 , 88–92

Rights & permissionsfor article Associations of menstrual pain with intakes of soy, fat and dietary fiber in Japanese women . Opens in a new window.
News and Views | 22 October 2010
Model, make, measure
- George K. H. Shimizu
Nature Chemistry 2 , 909–911

Rights & permissionsfor article Model, make, measure . Opens in a new window.
1 July 1997
Serum leptin concentration is associated with total body fat mass, but not abdominal fat distribution
- H Shimizu
- , Y Shimomura
- , R Hayashi
- , K Ohtani
- , N Sato
- , T Futawatari
- & M Mori
International Journal of Obesity 21 , 536–541

Rights & permissionsfor article Serum leptin concentration is associated with total body fat mass, but not abdominal fat distribution . Opens in a new window.
Research | 20 January 2008
Mechanical gas capture and release in a network solid via multiple single-crystalline transformations
Nature Materials 7 , 229–235

Rights & permissionsfor article Mechanical gas capture and release in a network solid via multiple single-crystalline transformations . Opens in a new window.
20 April 1998
Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats
- H Shimizu
- , K-I Ohtani
- , Y Uehara
- , Y Abe
- , H Takahashi
- , T Tsuchiya
- , N Sato
- , Y Ibuki
- & M Mori
International Journal of Obesity 22 , 318–324

Rights & permissionsfor article Orchiectomy and response to testosterone in the development of obesity in young Otsuka-Long-Evans-Tokushima Fatty (OLETF) rats . Opens in a new window.
Research | 7 October 1982
An actomyosin motor
- M. Yano
- , Y. Yamamoto
- & H. Shimizu
Nature 299 , 557–559

Rights & permissionsfor article An actomyosin motor . Opens in a new window.
20 June 2000 | Open
Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma
- G H Shen
- , M Ghazizadeh
- , O Kawanami
- , H Shimizu
- , E Jin
- , T Araki
- & Y Sugisaki
British Journal of Cancer 83 , 196–203

Rights & permissionsfor article Prognostic significance of vascular endothelial growth factor expression in human ovarian carcinoma . Opens in a new window.
25 June 2002 | Open
A prospective cohort study of soy product intake and stomach cancer death
- C Nagata
- , N Takatsuka
- , N Kawakami
- & H Shimizu
British Journal of Cancer 87 , 31–36

Rights & permissionsfor article A prospective cohort study of soy product intake and stomach cancer death . Opens in a new window.
14 June 2005 | Open
Mammographic density and the risk of breast cancer in Japanese women
- C Nagata
- , T Matsubara
- , H Fujita
- , Y Nagao
- , C Shibuya
- , Y Kashiki
- & H Shimizu
British Journal of Cancer 92 , 2102–2106

Rights & permissionsfor article Mammographic density and the risk of breast cancer in Japanese women . Opens in a new window.
12 April 2005
Inhibition of appetite by nasal leptin administration in rats
- H Shimizu
- , S Oh-I
- , S Okada
- & M Mori
International Journal of Obesity 29 , 858–863

Rights & permissionsfor article Inhibition of appetite by nasal leptin administration in rats . Opens in a new window.
1 September 1990
Serum oestrogen levels in postmenopausal women: comparison of American whites and Japanese in Japan
- H Shimizu
- , RK Ross
- , L Bernstein
- , MC Pike
- & BE Henderson
British Journal of Cancer 62 , 451–453

Rights & permissionsfor article Serum oestrogen levels in postmenopausal women: comparison of American whites and Japanese in Japan . Opens in a new window.
Research | 24 October 2008
The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells
- T Katsura
- , S Iwai
- , Y Ota
- , H Shimizu
- , K Ikuta
- & Y Yura
Cancer Gene Therapy 16 , 237–245

Rights & permissionsfor article The effects of trichostatin A on the oncolytic ability of herpes simplex virus for oral squamous cell carcinoma cells . Opens in a new window.
1 July 2008 | Open
FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer
- S Nomura
- , H Yoshitomi
- , S Takano
- , T Shida
- , S Kobayashi
- , M Ohtsuka
- , F Kimura
- , H Shimizu
- , H Yoshidome
- , A Kato
- & M Miyazaki
British Journal of Cancer 99 , 305–313

Rights & permissionsfor article FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer . Opens in a new window.
Research | 3 April 1986
A new geochronometer using lanthanum-138
- S. Nakai
- , H. Shimizu
- & A. Masuda
Nature 320 , 433–435

Rights & permissionsfor article A new geochronometer using lanthanum-138 . Opens in a new window.
12 November 1999 | Open
Serum carotenoids and vitamins and risk of cervical dysplasia from a case–control study in Japan
- C Nagata
- , H Shimizu
- , H Yoshikawa
- , K Noda
- , S Nozawa
- , A Yajima
- , S Sekiya
- , H Sugimori
- , Y Hirai
- , K Kanazawa
- , M Sugase
- & T Kawana
British Journal of Cancer 81 , 1234–1237

Rights & permissionsfor article Serum carotenoids and vitamins and risk of cervical dysplasia from a case–control study in Japan . Opens in a new window.
Research | 24 February 2005
Beta defensin-3 engineered epidermis shows highly protective effect for bacterial infection
- D Sawamura
- , M Goto
- , A Shibaki
- , M Akiyama
- , J R McMillan
- , Y Abiko
- & H Shimizu
Gene Therapy 12 , 857–861

Rights & permissionsfor article Beta defensin-3 engineered epidermis shows highly protective effect for bacterial infection . Opens in a new window.
Research | 19 January 1984
Meteoritic ¹³⁸Ce/¹⁴²Ce ratio and its evolution
- H. Shimizu
- , T. Tanaka
- & A. Masuda
Nature 307 , 251–252

Rights & permissionsfor article Meteoritic <sup>138</sup>Ce/<sup>142</sup>Ce ratio and its evolution . Opens in a new window.
Research | 1 January 2002
Polymorphic sequences of the tyrosinase gene: allele analysis on 16 OCA1 patients in Japan indicate that three polymorphic sequences in the tyrosinase gene promoter could be powerful markers for indirect gene diagnosis
- M. Tanita
- , J. Matsunaga
- , Y. Miyamura
- , M. Dakeishi
- , E. Nakamura
- , M. Kono
- , H. Shimizu
- , H. Tagami
- & Y. Tomita
Journal of Human Genetics 47 , 1–6

Rights & permissionsfor article Polymorphic sequences of the tyrosinase gene: allele analysis on 16 OCA1 patients in Japan indicate that three polymorphic sequences in the tyrosinase gene promoter could be powerful markers for indirect gene diagnosis . Opens in a new window.
14 June 2011 | Open
Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma
- M Miyamoto
- , H Ojima
- , M Iwasaki
- , H Shimizu
- , A Kokubu
- , N Hiraoka
- , T Kosuge
- , D Yoshikawa
- , T Kono
- , H Furukawa
- & T Shibata
British Journal of Cancer 105 , 131–138

Rights & permissionsfor article Prognostic significance of overexpression of c-Met oncoprotein in cholangiocarcinoma . Opens in a new window.
1 December 1991
Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County
- H Shimizu
- , RK Ross
- , L Bernstein
- , R Yatani
- , BE Henderson
- & TM Mack
British Journal of Cancer 63 , 963–966

Rights & permissionsfor article Cancers of the prostate and breast among Japanese and white immigrants in Los Angeles County . Opens in a new window.
1 April 2003 | Open
Height, weight, and alcohol consumption in relation to the risk of colorectal cancer in Japan: a prospective study
- N Shimizu
- , C Nagata
- , H Shimizu
- , M Kametani
- , N Takeyama
- , T Ohnuma
- & S Matsushita
British Journal of Cancer 88 , 1038–1043

Rights & permissionsfor article Height, weight, and alcohol consumption in relation to the risk of colorectal cancer in Japan: a prospective study . Opens in a new window.
1 August 1980
CLINICOPATHOLOGICAL OBSERVATION OF PURPURIC NEPHRITIS — REVIEW OF 41 CASES —
- S Yoshida
- , H Kawaguchi
- , H Shimizu
- , R Hosoya
- , K Eiraku
- , Y Takaue
- , K Nishimura
- , T Yamamoto
- , T Sakai
- , T Ishidate
- & K Iitaka
Pediatric Research 14 , 997–997

Rights & permissionsfor article CLINICOPATHOLOGICAL OBSERVATION OF PURPURIC NEPHRITIS — REVIEW OF 41 CASES — . Opens in a new window.
Research | 1 April 1975
Tumour induction study with n-amylhydrazine hydrochloride in Swiss mice
- H Shimizu
- , D Nagel
- & B Toth
British Journal of Cancer 31 , 492–496

Rights & permissionsfor article Tumour induction study with <i>n</i>-amylhydrazine hydrochloride in Swiss mice . Opens in a new window.
Research | 8 April 2004
Effect of nifedipine on endothelial function in normotensive smokers: potential contribution of increase in circulating hepatocyte growth factor
- K Yamasaki
- , M Aoki
- , H Makino
- , N Hashiya
- , H Shimizu
- , M Ohishi
- , T Ogihara
- & R Morishita
Journal of Human Hypertension 18 , 701–705

Rights & permissionsfor article Effect of nifedipine on endothelial function in normotensive smokers: potential contribution of increase in circulating hepatocyte growth factor . Opens in a new window.
Research | 2 March 2006
NFκB decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts
- H Shimizu
- , H Nakagami
- , I Tsukamoto
- , S Morita
- , Y Kunugiza
- , T Tomita
- , H Yoshikawa
- , Y Kaneda
- , T Ogihara
- & R Morishita
Gene Therapy 13 , 933–941

Rights & permissionsfor article NF<i>κ</i>B decoy oligodeoxynucleotides ameliorates osteoporosis through inhibition of activation and differentiation of osteoclasts . Opens in a new window.
17 December 1998
An increase of circulating leptin in patients with liver cirrhosis
- H Shimizu
- , S Kakizaki
- , T Tsuchiya
- , T Nagamine
- , H Takagi
- , H Takayama
- , I Kobayashi
- & M Mori
International Journal of Obesity 22 , 1234–1238

Rights & permissionsfor article An increase of circulating leptin in patients with liver cirrhosis . Opens in a new window.
Research | 5 January 2006
Hair follicle stem cell-targeted gene transfer and reconstitution system
Gene Therapy 13 , 732–737

Rights & permissionsfor article Hair follicle stem cell-targeted gene transfer and reconstitution system . Opens in a new window.
2 June 1988
Mantle and crustal Ce/Nd isotope systematics
- T. TANAKA
- , H. SHIMIZU
- , Y. KAWATA
- & A. MASUDA
Nature 333 , 404–404

Rights & permissionsfor article Mantle and crustal Ce/Nd isotope systematics . Opens in a new window.
9 April 1999 | Open
Human papillomavirus infection and other risk factors for cervical intraepithelial neoplasia in Japan
- H Yoshikawa
- , C Nagata
- , K Noda
- , S Nozawa
- , A Yajima
- , S Sekiya
- , H Sugimori
- , Y Hirai
- , K Kanazawa
- , M Sugase
- , H Shimizu
- & T Kawana
British Journal of Cancer 80 , 621–624

Rights & permissionsfor article Human papillomavirus infection and other risk factors for cervical intraepithelial neoplasia in Japan . Opens in a new window.
25 October 2002
Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees
- T Ohtsuki
- , H Ishiguro
- , S D Detera-Wadleigh
- , T Toyota
- , H Shimizu
- , K Yamada
- , K Yoshitsugu
- , E Hattori
- , T Yoshikawa
- & T Arinami
Molecular Psychiatry 7 , 954–961

Rights & permissionsfor article Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees . Opens in a new window.
Research | 8 May 2017
The RB–IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity
- S Kitajima
- , A Yoshida
- , S Kohno
- , F Li
- , S Suzuki
- , N Nagatani
- , Y Nishimoto
- , N Sasaki
- , H Muranaka
- , Y Wan
- , T C Thai
- , N Okahashi
- , F Matsuda
- , H Shimizu
- , T Nishiuchi
- , Y Suzuki
- , K Tominaga
- , N Gotoh
- , M Suzuki
- , M E Ewen
- , D A Barbie
- , O Hirose
- , T Tanaka
- & C Takahashi
Oncogene 36 , 5145–5157

Rights & permissionsfor article The RB–IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity . Opens in a new window.
Research | 27 March 2017
MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation
- K Otsubo
- , H Goto
- , M Nishio
- , K Kawamura
- , S Yanagi
- , W Nishie
- , T Sasaki
- , T Maehama
- , H Nishina
- , K Mimori
- , T Nakano
- , H Shimizu
- , T W Mak
- , K Nakao
- , Y Nakanishi
- & A Suzuki
Oncogene 36 , 4201–4211

Rights & permissionsfor article MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation . Opens in a new window.
24 March 2014
Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer
- F Hosoda
- , Y Arai
- , N Okada
- , H Shimizu
- , M Miyamoto
- , N Kitagawa
- , H Katai
- , H Taniguchi
- , K Yanagihara
- , I Imoto
- , J Inazawa
- , M Ohki
- & T Shibata
Oncogene 34 , 1196–1206

Rights & permissionsfor article Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer . Opens in a new window.
15 June 2010 | Open
Increased circulating cell signalling phosphoproteins in sera are useful for the detection of pancreatic cancer
- S Takano
- , K Sogawa
- , H Yoshitomi
- , T Shida
- , K Mogushi
- , F Kimura
- , H Shimizu
- , H Yoshidome
- , M Ohtsuka
- , A Kato
- , T Ishihara
- , H Tanaka
- , O Yokosuka
- , F Nomura
- & M Miyazaki
British Journal of Cancer 103 , 223–231

Rights & permissionsfor article Increased circulating cell signalling phosphoproteins in sera are useful for the detection of pancreatic cancer . Opens in a new window.
Research | 26 November 2007
Apolipoprotein C-1 maintains cell survival by preventing from apoptosis in pancreatic cancer cells
- S Takano
- , H Yoshitomi
- , A Togawa
- , K Sogawa
- , T Shida
- , F Kimura
- , H Shimizu
- , T Tomonaga
- , F Nomura
- & M Miyazaki
Oncogene 27 , 2810–2822

Rights & permissionsfor article Apolipoprotein C-1 maintains cell survival by preventing from apoptosis in pancreatic cancer cells . Opens in a new window.

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