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Research | 12 October 2020
GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision
- Kai Wang
- , Yuhui Chen
- , Sarah Ahn
- , Min Zheng
- , Elisa Landoni
- , Gianpietro Dotti
- , Barbara Savoldo
- & Zongchao Han
Nature Cancer 1 , 990–997

Rights & permissionsfor article GD2-specific CAR T cells encapsulated in an injectable hydrogel control retinoblastoma and preserve vision . Opens in a new window.
Research | 12 October 2020
Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis
- Andras Heczey
- , Amy N. Courtney
- , Antonino Montalbano
- , Simon Robinson
- , Ka Liu
- , Mingmei Li
- , Nisha Ghatwai
- , Olga Dakhova
- , Bin Liu
- , Tali Raveh-Sadka
- , Cynthia N. Chauvin-Fleurence
- , Xin Xu
- , Ho Ngai
- , Erica J. Di Pierro
- , Barbara Savoldo
- , Gianpietro Dotti
- & Leonid S. Metelitsa
Nature Medicine 26 , 1686–1690

Rights & permissionsfor article Anti-GD2 CAR-NKT cells in patients with relapsed or refractory neuroblastoma: an interim analysis . Opens in a new window.
Research | 23 September 2020 | Open
Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma
- Hsiang-chi Tseng
- , Wei Xiong
- , Saiaditya Badeti
- , Yan Yang
- , Minh Ma
- , Ting Liu
- , Carlos A. Ramos
- , Gianpietro Dotti
- , Luke Fritzky
- , Jie-gen Jiang
- , Qing Yi
- , James Guarrera
- , Wei-Xing Zong
- , Chen Liu
- & Dongfang Liu
Nature Communications 11 , 1–15

Rights & permissionsfor article Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma . Opens in a new window.
Research | 15 July 2020 | Open
Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma
- Meenakshi Hegde
- , Sujith K. Joseph
- , Farzana Pashankar
- , Christopher DeRenzo
- , Khaled Sanber
- , Shoba Navai
- , Tiara T. Byrd
- , John Hicks
- , Mina L. Xu
- , Claudia Gerken
- , Mamta Kalra
- , Catherine Robertson
- , Huimin Zhang
- , Ankita Shree
- , Birju Mehta
- , Olga Dakhova
- , Vita S. Salsman
- , Bambi Grilley
- , Adrian Gee
- , Gianpietro Dotti
- , Helen E. Heslop
- , Malcolm K. Brenner
- , Winfried S. Wels
- , Stephen Gottschalk
- & Nabil Ahmed
Nature Communications 11 , 1–15

Rights & permissionsfor article Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma . Opens in a new window.
Research | 3 February 2020
Interleukin-23 engineering improves CAR T cell function in solid tumors
- Xingcong Ma
- , Peishun Shou
- , Christof Smith
- , Yuhui Chen
- , Hongwei Du
- , Chuang Sun
- , Nancy Porterfield Kren
- , Daniel Michaud
- , Sarah Ahn
- , Benjamin Vincent
- , Barbara Savoldo
- , Yuliya Pylayeva-Gupta
- , Shuqun Zhang
- , Gianpietro Dotti
- & Yang Xu
Nature Biotechnology 38 , 448–459

Rights & permissionsfor article Interleukin-23 engineering improves CAR T cell function in solid tumors . Opens in a new window.
Research | 10 December 2018
In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
- Qian Chen
- , Chao Wang
- , Xudong Zhang
- , Guojun Chen
- , Quanyin Hu
- , Hongjun Li
- , Jinqiang Wang
- , Di Wen
- , Yuqi Zhang
- , Yifei Lu
- , Guang Yang
- , Chen Jiang
- , Jun Wang
- , Gianpietro Dotti
- & Zhen Gu
Nature Nanotechnology 14 , 89–97

Rights & permissionsfor article In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment . Opens in a new window.
Research | 29 October 2018
Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy
- Quanyin Hu
- , Wujin Sun
- , Jinqiang Wang
- , Huitong Ruan
- , Xudong Zhang
- , Yanqi Ye
- , Song Shen
- , Chao Wang
- , Weiyue Lu
- , Ke Cheng
- , Gianpietro Dotti
- , Joshua F. Zeidner
- , Jun Wang
- & Zhen Gu
Nature Biomedical Engineering 2 , 831–840

Rights & permissionsfor article Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy . Opens in a new window.
Research | 13 April 2015
Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes
- Gianpietro Dotti and colleagues report that CAR...
- Ignazio Caruana
- , Barbara Savoldo
- , Valentina Hoyos
- , Gerrit Weber
- , Hao Liu
- , Eugene S Kim
- , Michael M Ittmann
- , Dario Marchetti
- & Gianpietro Dotti
Nature Medicine 21 , 524–529

Rights & permissionsfor article Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes . Opens in a new window.
Research | 2 November 2008
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
- Martin A Pule
- , Barbara Savoldo
- , G Doug Myers
- , Claudia Rossig
- , Heidi V Russell
- , Gianpietro Dotti
- , M Helen Huls
- , Enli Liu
- , Adrian P Gee
- , Zhuyong Mei
- , Eric Yvon
- , Heidi L Weiss
- , Hao Liu
- , Cliona M Rooney
- , Helen E Heslop
- & Malcolm K Brenner
Nature Medicine 14 , 1264–1270

Rights & permissionsfor article Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma . Opens in a new window.

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