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Correspondence | 1 April 2006
Explaining the biological activity of transactivation-deficient p53 variants
Nature Genetics 38 , 395–396

Rights & permissionsfor article Explaining the biological activity of transactivation-deficient p53 variants . Opens in a new window.
Research | 1 January 1999
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype
- Xu-Rong Jiang
- , Gretchen Jimenez
- , Edwin Chang
- , Maria Frolkis
- , Brenda Kusler
- , Marijke Sage
- , Michelle Beeche
- , Andrea G. Bodnar
- , Geoffrey M. Wahl
- , Thea D. Tlsty
- & Choy-Pik Chiu
Nature Genetics 21 , 111–114

Rights & permissionsfor article Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype . Opens in a new window.
Research | 1 July 1999
DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage
Nature 400 , 81–83

Rights & permissionsfor article DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage . Opens in a new window.
Research | 9 August 2009
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
Nature 460 , 1140–1144

Rights & permissionsfor article Linking the p53 tumour suppressor pathway to somatic cell reprogramming . Opens in a new window.
17 July 1997
p53-mediated accumulation of hypophosphorylated pRb after the G₁ restriction point fails to halt cell cycle progression
Oncogene 15 , 337–345

Rights & permissionsfor article p53-mediated accumulation of hypophosphorylated pRb after the G1 restriction point fails to halt cell cycle progression . Opens in a new window.
Research | 9 February 1984
Effect of chromosomal position on amplification of transfected genes in animal cells
Nature 307 , 516–520

Rights & permissionsfor article Effect of chromosomal position on amplification of transfected genes in animal cells . Opens in a new window.
Research | 17 April 2019
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
- Yu Shi
- , Weina Gao
- , Nikki K. Lytle
- , Peiwu Huang
- , Xiao Yuan
- , Amanda M. Dann
- , Maya Ridinger-Saison
- , Kathleen E. DelGiorno
- , Corina E. Antal
- , Gaoyang Liang
- , Annette R. Atkins
- , Galina Erikson
- , Huaiyu Sun
- , Jill Meisenhelder
- , Elena Terenziani
- , Gyunghwi Woo
- , Linjing Fang
- , Thom P. Santisakultarm
- , Uri Manor
- , Ruilian Xu
- , Carlos R. Becerra
- , Erkut Borazanci
- , Daniel D. Von Hoff
- , Paul M. Grandgenett
- , Michael A. Hollingsworth
- , Mathias Leblanc
- , Sarah E. Umetsu
- , Eric A. Collisson
- , Miriam Scadeng
- , Andrew M. Lowy
- , Timothy R. Donahue
- , Tannishtha Reya
- , Michael Downes
- , Ronald M. Evans
- , Geoffrey M. Wahl
- , Tony Pawson
- , Ruijun Tian
- & Tony Hunter
Nature 569 , 131–135

Rights & permissionsfor article Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring . Opens in a new window.
Research | 24 April 2017 | Open
Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis
npj Breast Cancer 3 , 1–11

Rights & permissionsfor article Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis . Opens in a new window.
Reviews | 19 April 2017 | Open
Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity
- Geoffrey M. Wahl
- & Benjamin T. Spike
npj Breast Cancer 3 , 1–13

Rights & permissionsfor article Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity . Opens in a new window.
Research | 8 February 2017
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity
- Kristen M. Turner
- , Viraj Deshpande
- , Doruk Beyter
- , Tomoyuki Koga
- , Jessica Rusert
- , Catherine Lee
- , Bin Li
- , Karen Arden
- , Bing Ren
- , David A. Nathanson
- , Harley I. Kornblum
- , Michael D. Taylor
- , Sharmeela Kaushal
- , Webster K. Cavenee
- , Robert Wechsler-Reya
- , Frank B. Furnari
- , Scott R. Vandenberg
- , P. Nagesh Rao
- , Geoffrey M. Wahl
- , Vineet Bafna
- & Paul S. Mischel
Nature 543 , 122–125

Rights & permissionsfor article Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity . Opens in a new window.
Research | 22 February 2016 | Open
Establishment of human iPSC-based models for the study and targeting of glioma initiating cells
- Ignacio Sancho-Martinez
- , Emmanuel Nivet
- , Yun Xia
- , Tomoaki Hishida
- , Aitor Aguirre
- , Alejandro Ocampo
- , Li Ma
- , Robert Morey
- , Marie N. Krause
- , Andreas Zembrzycki
- , Olaf Ansorge
- , Eric Vazquez-Ferrer
- , Ilir Dubova
- , Pradeep Reddy
- , David Lam
- , Yuriko Hishida
- , Min-Zu Wu
- , Concepcion Rodriguez Esteban
- , Dennis O’Leary
- , Geoffrey M. Wahl
- , Inder M. Verma
- , Louise C. Laurent
- & Juan Carlos Izpisua Belmonte
Nature Communications 7 , 1–14

Rights & permissionsfor article Establishment of human iPSC-based models for the study and targeting of glioma initiating cells . Opens in a new window.
7 March 2005
p53 must be competent for transcriptional regulation to suppress tumor formation
- Monica Nistér
- , Mengjia Tang
- , Xiao-Qun Zhang
- , Chaoying Yin
- , Michelle Beeche
- , Xinrong Hu
- , Gunilla Enblad
- , Terry van Dyke
- & Geoffrey M Wahl
Oncogene 24 , 3563–3573

Rights & permissionsfor article p53 must be competent for transcriptional regulation to suppress tumor formation . Opens in a new window.
24 December 1999
p53 regulation by post-translational modification and nuclear retention in response to diverse stresses
Oncogene 18 , 7656–7665

Rights & permissionsfor article p53 regulation by post-translational modification and nuclear retention in response to diverse stresses . Opens in a new window.
Research | 1 January 1996
Selective capture of acentric fragments by micronuclei provides a rapid method for purifying extrachromosomally amplified DNA
Nature Genetics 12 , 65–71

Rights & permissionsfor article Selective capture of acentric fragments by micronuclei provides a rapid method for purifying extrachromosomally amplified DNA . Opens in a new window.
Reviews | 1 December 2006
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
- Franck Toledo
- & Geoffrey M. Wahl
Nature Reviews Cancer 6 , 909–923

Rights & permissionsfor article Regulating the p53 pathway: in vitro hypotheses, in vivo veritas . Opens in a new window.
Reviews | 10 January 2013
MDM2, MDMX and p53 in oncogenesis and cancer therapy
Nature Reviews Cancer 13 , 83–96

Rights & permissionsfor article MDM2, MDMX and p53 in oncogenesis and cancer therapy . Opens in a new window.
Reviews | 1 December 2001
The evolution of diverse biological responses to DNA damage: insights from yeast and p53
- Geoffrey M. Wahl
- & Antony M. Carr
Nature Cell Biology 3 , E277–E286

Rights & permissionsfor article The evolution of diverse biological responses to DNA damage: insights from yeast and p53 . Opens in a new window.
Research | 1 September 2000
A transactivation-deficient mouse model provides insights into Trp53 regulation and function
Nature Genetics 26 , 37–43

Rights & permissionsfor article A transactivation-deficient mouse model provides insights into Trp53 regulation and function . Opens in a new window.

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Explaining the biological activity of transactivation-deficient p53 variants

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

DNA-dependent protein kinase is not required for the p53-dependent response to DNA damage

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

p53-mediated accumulation of hypophosphorylated pRb after the G₁ restriction point fails to halt cell cycle progression

Effect of chromosomal position on amplification of transfected genes in animal cells

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring

Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis

Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity

Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells

p53 must be competent for transcriptional regulation to suppress tumor formation

p53 regulation by post-translational modification and nuclear retention in response to diverse stresses

Selective capture of acentric fragments by micronuclei provides a rapid method for purifying extrachromosomally amplified DNA

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

MDM2, MDMX and p53 in oncogenesis and cancer therapy

The evolution of diverse biological responses to DNA damage: insights from yeast and p53

A transactivation-deficient mouse model provides insights into Trp53 regulation and function

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