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Research | 22 May 2017 | Open
In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia
- Eugene Makarev
- , Adrian D Schubert
- , Riya R Kanherkar
- , Nyall London
- , Mahder Teka
- , Ivan Ozerov
- , Ksenia Lezhnina
- , Atul Bedi
- , Rajani Ravi
- , Rannee Mehra
- , Mohammad O Hoque
- , Ido Sloma
- , Daria A Gaykalova
- , Antonei B Csoka
- , David Sidransky
- , Alex Zhavoronkov
- & Evgeny Izumchenko
Cell Death Discovery 3 , 1–7

Rights & permissionsfor article In silico analysis of pathways activation landscape in oral squamous cell carcinoma and oral leukoplakia . Opens in a new window.
Research | 21 February 2018 | Open
Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy
- Rajani Ravi
- , Kimberly A. Noonan
- , Vui Pham
- , Rishi Bedi
- , Alex Zhavoronkov
- , Ivan V. Ozerov
- , Eugene Makarev
- , Artem V. Artemov
- , Piotr T. Wysocki
- , Ranee Mehra
- , Sridhar Nimmagadda
- , Luigi Marchionni
- , David Sidransky
- , Ivan M. Borrello
- , Evgeny Izumchenko
- & Atul Bedi
Nature Communications 9 , 1–14

Rights & permissionsfor article Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy . Opens in a new window.
Research | 24 November 2017 | Open
NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis
- Suraj Peri
- , Evgeny Izumchenko
- , Adrian D. Schubert
- , Michael J. Slifker
- , Karen Ruth
- , Ilya G. Serebriiskii
- , Theresa Guo
- , Barbara A. Burtness
- , Ranee Mehra
- , Eric A. Ross
- , David Sidransky
- & Erica A. Golemis
Nature Communications 8 , 1–10

Rights & permissionsfor article NSD1- and NSD2-damaging mutations define a subset of laryngeal tumors with favorable prognosis . Opens in a new window.
24 January 2017 | Open
Comparative mutational landscape analysis of patient-derived tumour xenografts
- Mariana Brait
- , Evgeny Izumchenko
- , Luciane T Kagohara
- , Samuel Long
- , Piotr T Wysocki
- , Brian Faherty
- , Elana J Fertig
- , Tin Oo Khor
- , Elizabeth Bruckheimer
- , Gilson Baia
- , Daniel Ciznadija
- , Ido Sloma
- , Ido Ben-Zvi
- , Keren Paz
- & David Sidransky
British Journal of Cancer 116 , 515–523

Rights & permissionsfor article Comparative mutational landscape analysis of patient-derived tumour xenografts . Opens in a new window.
Research | 16 November 2016 | Open
In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development
- Ivan V. Ozerov
- , Ksenia V. Lezhnina
- , Evgeny Izumchenko
- , Artem V. Artemov
- , Sergey Medintsev
- , Quentin Vanhaelen
- , Alexander Aliper
- , Jan Vijg
- , Andreyan N. Osipov
- , Ivan Labat
- , Michael D. West
- , Anton Buzdin
- , Charles R. Cantor
- , Yuri Nikolsky
- , Nikolay Borisov
- , Irina Irincheeva
- , Edward Khokhlovich
- , David Sidransky
- , Miguel Luiz Camargo
- & Alex Zhavoronkov
Nature Communications 7 , 1–11

Rights & permissionsfor article In silico Pathway Activation Network Decomposition Analysis (iPANDA) as a method for biomarker development . Opens in a new window.
Research | 28 August 2015 | Open
An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation
- Shahnaz Begum
- , Masamichi Hayashi
- , Takenori Ogawa
- , Fayez J. Jabboure
- , Mariana Brait
- , Evgeny Izumchenko
- , Sarit Tabak
- , Steven A. Ahrendt
- , William H. Westra
- , Wayne Koch
- , David Sidransky
- & Mohammad O. Hoque
Scientific Reports 5 , 1–16

Rights & permissionsfor article An integrated genome-wide approach to discover deregulated microRNAs in non-small cell lung cancer: Clinical significance of miR-23b-3p deregulation . Opens in a new window.
Research | 2 April 2015 | Open
Pathway activation strength is a novel independent prognostic biomarker for cetuximab sensitivity in colorectal cancer patients
- Qingsong Zhu
- , Evgeny Izumchenko
- , Alexander M Aliper
- , Evgeny Makarev
- , Keren Paz
- , Anton A Buzdin
- , Alex A Zhavoronkov
- & David Sidransky
Human Genome Variation 2 , 1–9

Rights & permissionsfor article Pathway activation strength is a novel independent prognostic biomarker for cetuximab sensitivity in colorectal cancer patients . Opens in a new window.
Research | 16 September 2015 | Open
Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA
- Evgeny Izumchenko
- , Xiaofei Chang
- , Mariana Brait
- , Elana Fertig
- , Luciane T. Kagohara
- , Atul Bedi
- , Luigi Marchionni
- , Nishant Agrawal
- , Rajani Ravi
- , Sian Jones
- , Mohammad O. Hoque
- , William H. Westra
- & David Sidransky
Nature Communications 6 , 1–13

Rights & permissionsfor article Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA . Opens in a new window.

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