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1 April 1996
SKEWING OF THE T CELL REPERTOIRE TOWARD A TARGET ANTIGEN DURING A PERIOD OF T CELL IMMUNE RECONSTITUTION. • 935
- Crystal L Mackall
- & Ronald E Gress
Pediatric Research 39 , 158–158

Rights & permissionsfor article SKEWING OF THE T CELL REPERTOIRE TOWARD A TARGET ANTIGEN DURING A PERIOD OF T CELL IMMUNE RECONSTITUTION. • 935 . Opens in a new window.
Research | 21 October 2020
Immune receptor inhibition through enforced phosphatase recruitment
- Ricardo A. Fernandes
- , Leon Su
- , Yoko Nishiga
- , Junming Ren
- , Aladdin M. Bhuiyan
- , Ning Cheng
- , Calvin J. Kuo
- , Lora K. Picton
- , Shozo Ohtsuki
- , Robbie G. Majzner
- , Skyler P. Rietberg
- , Crystal L. Mackall
- , Qian Yin
- , Lestat R. Ali
- , Xinbo Yang
- , Christina S. Savvides
- , Julien Sage
- , Michael Dougan
- & K. Christopher Garcia
Nature 586 , 779–784

Rights & permissionsfor article Immune receptor inhibition through enforced phosphatase recruitment . Opens in a new window.
Comments and Opinion | 10 January 2019
CAR T cell therapy: inroads to response and resistance
- Christine E. Brown
- & Crystal L. Mackall
Nature Reviews Immunology 19 , 73–74

Rights & permissionsfor article CAR T cell therapy: inroads to response and resistance . Opens in a new window.
Correspondence | 1 July 2010
Reply to “Is IL-7 from dendritic cells essential for the homeostasis of CD4⁺ T cells?”
- Crystal L Mackall
- & Martin Guimond
Nature Immunology 11 , 548–548

Rights & permissionsfor article Reply to “Is IL-7 from dendritic cells essential for the homeostasis of CD4+ T cells?” . Opens in a new window.
1 April 1996
IMPAIRED IMMUNE RECONSTITUTION POST SEQUENTIAL HIGH-DOSE CHEMOTHERAPY AND PERIPHERAL BLOOD PROGENITOR CELL (PBPC) INFUSION. † 962
- Dagmar T Stein
- , Crystal L Mackall
- , Catherine V Bare
- , Margaret R Brown
- , Charles S Carter
- , Naomi Casey
- , Monica Y Yu
- , Thomas A Fleisher
- , Susan F Leitman
- , Gene M Shearer
- , Leonard Wexler
- & Ronald E Gress
Pediatric Research 39 , 163–163

Rights & permissionsfor article IMPAIRED IMMUNE RECONSTITUTION POST SEQUENTIAL HIGH-DOSE CHEMOTHERAPY AND PERIPHERAL BLOOD PROGENITOR CELL (PBPC) INFUSION. † 962 . Opens in a new window.
Research | 13 July 2020
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals
- Yichi Su
- , Joel R. Walker
- , Yunhee Park
- , Thomas P. Smith
- , Lan Xiang Liu
- , Mary P. Hall
- , Louai Labanieh
- , Robin Hurst
- , David C. Wang
- , Lance P. Encell
- , Namdoo Kim
- , Feijie Zhang
- , Mark A. Kay
- , Kerriann M. Casey
- , Robbie G. Majzner
- , Jennifer R. Cochran
- , Crystal L. Mackall
- , Thomas A. Kirkland
- & Michael Z. Lin
Nature Methods 17 , 852–860

Rights & permissionsfor article Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals . Opens in a new window.
Research | 27 April 2020
Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors
- Johanna Theruvath
- , Elena Sotillo
- , Christopher W. Mount
- , Claus Moritz Graef
- , Alberto Delaidelli
- , Sabine Heitzeneder
- , Louai Labanieh
- , Shaurya Dhingra
- , Amaury Leruste
- , Robbie G. Majzner
- , Peng Xu
- , Sabine Mueller
- , Derek W. Yecies
- , Martina A. Finetti
- , Daniel Williamson
- , Pascal D. Johann
- , Marcel Kool
- , Stefan Pfister
- , Martin Hasselblatt
- , Michael C. Frühwald
- , Olivier Delattre
- , Didier Surdez
- , Franck Bourdeaut
- , Stephanie Puget
- , Sakina Zaidi
- , Siddhartha S. Mitra
- , Samuel Cheshier
- , Poul H. Sorensen
- , Michelle Monje
- & Crystal L. Mackall
Nature Medicine 26 , 712–719

Rights & permissionsfor article Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors . Opens in a new window.
Research | 16 October 2005
Lymphopenia and interleukin-2 therapy alter homeostasis of CD4⁺CD25⁺ regulatory T cells
- Hua Zhang
- , Kevin S Chua
- , Martin Guimond
- , Veena Kapoor
- , Margaret V Brown
- , Thomas A Fleisher
- , Lauren M. Long
- , Donna Bernstein
- , Brenna J Hill
- , Daniel C Douek
- , Jay A Berzofsky
- , Charles S Carter
- , E J Read
- , Lee J Helman
- & Crystal L Mackall
Nature Medicine 11 , 1238–1243

Rights & permissionsfor article Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells . Opens in a new window.
Research | 4 December 2019
c-Jun overexpression in CAR T cells induces exhaustion resistance
- Rachel C. Lynn
- , Evan W. Weber
- , Elena Sotillo
- , David Gennert
- , Peng Xu
- , Zinaida Good
- , Hima Anbunathan
- , John Lattin
- , Robert Jones
- , Victor Tieu
- , Surya Nagaraja
- , Jeffrey Granja
- , Charles F. A. de Bourcy
- , Robbie Majzner
- , Ansuman T. Satpathy
- , Stephen R. Quake
- , Michelle Monje
- , Howard Y. Chang
- & Crystal L. Mackall
Nature 576 , 293–300

Rights & permissionsfor article c-Jun overexpression in CAR T cells induces exhaustion resistance . Opens in a new window.
Reviews | 9 September 2019
Clinical lessons learned from the first leg of the CAR T cell journey
- Robbie G. Majzner
- & Crystal L. Mackall
Nature Medicine 25 , 1341–1355

Rights & permissionsfor article Clinical lessons learned from the first leg of the CAR T cell journey . Opens in a new window.
Comments and Opinion | 7 May 2018 | Open
Fludarabine and neurotoxicity in engineered T-cell therapy
Gene Therapy 25 , 176–191

Rights & permissionsfor article Fludarabine and neurotoxicity in engineered T-cell therapy . Opens in a new window.
Research | 16 April 2018
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M⁺ diffuse midline gliomas
- Christopher W. Mount
- , Robbie G. Majzner
- , Shree Sundaresh
- , Evan P. Arnold
- , Meena Kadapakkam
- , Samuel Haile
- , Louai Labanieh
- , Esther Hulleman
- , Pamelyn J. Woo
- , Skyler P. Rietberg
- , Hannes Vogel
- , Michelle Monje
- & Crystal L. Mackall
Nature Medicine 24 , 572–579

Rights & permissionsfor article Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M+ diffuse midline gliomas . Opens in a new window.
Reviews | 11 June 2018
Programming CAR-T cells to kill cancer
Nature Biomedical Engineering 2 , 377–391

Rights & permissionsfor article Programming CAR-T cells to kill cancer . Opens in a new window.
Research | 20 November 2017
CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy
- Terry J Fry
- , Nirali N Shah
- , Rimas J Orentas
- , Maryalice Stetler-Stevenson
- , Constance M Yuan
- , Sneha Ramakrishna
- , Pamela Wolters
- , Staci Martin
- , Cindy Delbrook
- , Bonnie Yates
- , Haneen Shalabi
- , Thomas J Fountaine
- , Jack F Shern
- , Robbie G Majzner
- , David F Stroncek
- , Marianna Sabatino
- , Yang Feng
- , Dimiter S Dimitrov
- , Ling Zhang
- , Sang Nguyen
- , Haiying Qin
- , Boro Dropulic
- , Daniel W Lee
- & Crystal L Mackall
Nature Medicine 24 , 20–28

Rights & permissionsfor article CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy . Opens in a new window.
Reviews | 10 November 2016
Neuroblastoma
Nature Reviews Disease Primers 2 , 1–21

Rights & permissionsfor article Neuroblastoma . Opens in a new window.
Research | 27 July 2016 | Open
CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity
- Elad Jacoby
- , Sang M. Nguyen
- , Thomas J. Fountaine
- , Kathryn Welp
- , Berkley Gryder
- , Haiying Qin
- , Yinmeng Yang
- , Christopher D. Chien
- , Alix E. Seif
- , Haiyan Lei
- , Young K. Song
- , Javed Khan
- , Daniel W. Lee
- , Crystal L. Mackall
- , Rebecca A. Gardner
- , Michael C. Jensen
- , Jack F. Shern
- & Terry J. Fry
Nature Communications 7 , 1–10

Rights & permissionsfor article CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity . Opens in a new window.
Reviews | 28 October 2014
Immune-based therapies for childhood cancer
Nature Reviews Clinical Oncology 11 , 693–703

Rights & permissionsfor article Immune-based therapies for childhood cancer . Opens in a new window.
Research | 4 May 2015
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
- Adrienne H Long
- , Waleed M Haso
- , Jack F Shern
- , Kelsey M Wanhainen
- , Meera Murgai
- , Maria Ingaramo
- , Jillian P Smith
- , Alec J Walker
- , M Eric Kohler
- , Vikas R Venkateshwara
- , Rosandra N Kaplan
- , George H Patterson
- , Terry J Fry
- , Rimas J Orentas
- & Crystal L Mackall
Nature Medicine 21 , 581–590

Rights & permissionsfor article 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors . Opens in a new window.
Research | 11 January 2009
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4⁺ T cells
- Martin Guimond
- , Rachelle G Veenstra
- , David J Grindler
- , Hua Zhang
- , Yongzhi Cui
- , Ryan D Murphy
- , Su Young Kim
- , Risu Na
- , Lothar Hennighausen
- , Sema Kurtulus
- , Batu Erman
- , Polly Matzinger
- , Melinda S Merchant
- & Crystal L Mackall
Nature Immunology 10 , 149–157

Rights & permissionsfor article Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells . Opens in a new window.
Reviews | 21 April 2011
Harnessing the biology of IL-7 for therapeutic application
Nature Reviews Immunology 11 , 330–342

Rights & permissionsfor article Harnessing the biology of IL-7 for therapeutic application . Opens in a new window.

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SKEWING OF THE T CELL REPERTOIRE TOWARD A TARGET ANTIGEN DURING A PERIOD OF T CELL IMMUNE RECONSTITUTION. • 935

Immune receptor inhibition through enforced phosphatase recruitment

CAR T cell therapy: inroads to response and resistance

Reply to “Is IL-7 from dendritic cells essential for the homeostasis of CD4⁺ T cells?”

IMPAIRED IMMUNE RECONSTITUTION POST SEQUENTIAL HIGH-DOSE CHEMOTHERAPY AND PERIPHERAL BLOOD PROGENITOR CELL (PBPC) INFUSION. † 962

Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals

Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4⁺CD25⁺ regulatory T cells

c-Jun overexpression in CAR T cells induces exhaustion resistance

Clinical lessons learned from the first leg of the CAR T cell journey

Fludarabine and neurotoxicity in engineered T-cell therapy

Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M⁺ diffuse midline gliomas

Programming CAR-T cells to kill cancer

CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

Neuroblastoma

CD19 CAR immune pressure induces B-precursor acute lymphoblastic leukaemia lineage switch exposing inherent leukaemic plasticity

Immune-based therapies for childhood cancer

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4⁺ T cells

Harnessing the biology of IL-7 for therapeutic application

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