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Research | 25 April 2019
Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma
Modern Pathology 32 , 1544–1550

Rights & permissionsfor article Incidence and distribution of UroSEEK gene panel in a multi-institutional cohort of bladder urothelial carcinoma . Opens in a new window.
Research | 21 December 2018 | Open
Genomic analysis identifies frequent deletions of Dystrophin in olfactory neuroblastoma
- Gary L. Gallia
- , Ming Zhang
- , Yi Ning
- , Michael C. Haffner
- , Denise Batista
- , Zev A. Binder
- , Justin A. Bishop
- , Christine L. Hann
- , Ralph H. Hruban
- , Masaru Ishii
- , Alison P. Klein
- , Douglas D. Reh
- , Lisa M. Rooper
- , Vafi Salmasi
- , Rafael J. Tamargo
- , Qing Wang
- , Tara Williamson
- , Tianna Zhao
- , Ying Zou
- , Alan K. Meeker
- , Nishant Agrawal
- , Bert Vogelstein
- , Kenneth W. Kinzler
- , Nickolas Papadopoulos
- & Chetan Bettegowda
Nature Communications 9 , 1–6

Rights & permissionsfor article Genomic analysis identifies frequent deletions of <i>Dystrophin</i> in olfactory neuroblastoma . Opens in a new window.
Research | 10 August 2017
Role of stem-cell divisions in cancer risk
- Cristian Tomasetti
- , Rick Durrett
- , Marek Kimmel
- , Amaury Lambert
- , Giovanni Parmigiani
- , Ann Zauber
- & Bert Vogelstein
Nature 548 , E13–E14

Rights & permissionsfor article Role of stem-cell divisions in cancer risk . Opens in a new window.
Research | 17 December 2015 | Open
PRINT: A Protein Bioconjugation Method with Exquisite N-terminal Specificity
- Surojit Sur
- , Yuan Qiao
- , Anja Fries
- , Robert N. O’Meally
- , Robert N. Cole
- , Kenneth W. Kinzler
- , Bert Vogelstein
- & Shibin Zhou
Scientific Reports 5 , 1–7

Rights & permissionsfor article PRINT: A Protein Bioconjugation Method with Exquisite N-terminal Specificity . Opens in a new window.
Research | 11 March 2016
High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder
- Morgan Cowan
- , Simeon Springer
- , Doreen Nguyen
- , Diana Taheri
- , Gunes Guner
- , Maria Angelica Mendoza Rodriguez
- , Yuxuan Wang
- , Isaac Kinde
- , Christopher J VandenBussche
- , Matthew T Olson
- , Isabela Cunha
- , Kazutoshi Fujita
- , Dilek Ertoy
- , Trinity J Bivalacqua
- , Kenneth Kinzler
- , Bert Vogelstein
- , George J Netto
- & Nickolas Papadopoulos
Modern Pathology 29 , 511–515

Rights & permissionsfor article High prevalence of <i>TERT</i> promoter mutations in primary squamous cell carcinoma of the urinary bladder . Opens in a new window.
Research | 12 October 2014
Somatic mutations of SUZ12 in malignant peripheral nerve sheath tumors
- Chetan Bettegowda, Bert Vogelstein and colleagues identify somatic mutations...
- Ming Zhang
- , Yuxuan Wang
- , Sian Jones
- , Mark Sausen
- , Kevin McMahon
- , Rajni Sharma
- , Qing Wang
- , Allan J Belzberg
- , Kaisorn Chaichana
- , Gary L Gallia
- , Ziya L Gokaslan
- , Greg J Riggins
- , Jean-Paul Wolinksy
- , Laura D Wood
- , Elizabeth A Montgomery
- , Ralph H Hruban
- , Kenneth W Kinzler
- , Nickolas Papadopoulos
- , Bert Vogelstein
- & Chetan Bettegowda
Nature Genetics 46 , 1170–1172

Rights & permissionsfor article Somatic mutations of <i>SUZ12</i> in malignant peripheral nerve sheath tumors . Opens in a new window.
Research | 3 November 2013
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
- Yuchen Jiao
- , Timothy M Pawlik
- , Robert A Anders
- , Florin M Selaru
- , Mirte M Streppel
- , Donald J Lucas
- , Noushin Niknafs
- , Violeta Beleva Guthrie
- , Anirban Maitra
- , Pedram Argani
- , G Johan A Offerhaus
- , Juan Carlos Roa
- , Lewis R Roberts
- , Gregory J Gores
- , Irinel Popescu
- , Sorin T Alexandrescu
- , Simona Dima
- , Matteo Fassan
- , Michele Simbolo
- , Andrea Mafficini
- , Paola Capelli
- , Rita T Lawlor
- , Andrea Ruzzenente
- , Alfredo Guglielmi
- , Giampaolo Tortora
- , Filippo de Braud
- , Aldo Scarpa
- , William Jarnagin
- , David Klimstra
- , Rachel Karchin
- , Victor E Velculescu
- , Ralph H Hruban
- , Bert Vogelstein
- , Kenneth W Kinzler
- , Nickolas Papadopoulos
- & Laura D Wood
Nature Genetics 45 , 1470–1473

Rights & permissionsfor article Exome sequencing identifies frequent inactivating mutations in <i>BAP1</i>, <i>ARID1A</i> and <i>PBRM1</i> in intrahepatic cholangiocarcinomas . Opens in a new window.
Research | 1 June 2001
Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
Nature Genetics 28 , 184–187

Rights & permissionsfor article Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis . Opens in a new window.
Research | 28 May 1987
Prevalence of ras gene mutations in human colorectal cancers
Nature 327 , 293–297

Rights & permissionsfor article Prevalence of <i>ras</i> gene mutations in human colorectal cancers . Opens in a new window.
Research | 20 June 1996
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
Nature 381 , 713–716

Rights & permissionsfor article Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21 . Opens in a new window.
Research | 10 August 2003
Multicolor in vitro translation
- Giovanni Traverso
- , Frank Diehl
- , Robin Hurst
- , Anthony Shuber
- , Duncan Whitney
- , Constance Johnson
- , Bernard Levin
- , Kenneth W Kinzler
- & Bert Vogelstein
Nature Biotechnology 21 , 1093–1097

Rights & permissionsfor article Multicolor <i>in vitro</i> translation . Opens in a new window.
News and Views | 4 January 1996
Life (and death) in a malignant tumour
- Kenneth W. Kinzler
- & Bert Vogelstein
Nature 379 , 19–20

Rights & permissionsfor article Life (and death) in a malignant tumour . Opens in a new window.
Research | 7 October 1999
14-3-3σ is required to prevent mitotic catastrophe after DNA damage
Nature 401 , 616–620

Rights & permissionsfor article 14-3-3σ is required to prevent mitotic catastrophe after DNA damage . Opens in a new window.
News and Views | 24 April 1997
Gatekeepers and caretakers
- Kenneth W. Kinzler
- & Bert Vogelstein
Nature 386 , 761–763

Rights & permissionsfor article Gatekeepers and caretakers . Opens in a new window.
1 April 1987
WISKOTT-ALDRICH SYNDROME (WAS) CARRIER DETECTION BY X-CHROMOSOME INACTIVATION ANALYSIS
Pediatric Research 21 , 313–313

Rights & permissionsfor article WISKOTT-ALDRICH SYNDROME (WAS) CARRIER DETECTION BY X-CHROMOSOME INACTIVATION ANALYSIS . Opens in a new window.
Research | 7 August 2011
Inactivating mutations of the chromatin remodeling gene ARID2 in hepatocellular carcinoma
- Meng Li
- , Hong Zhao
- , Xiaosong Zhang
- , Laura D Wood
- , Robert A Anders
- , Michael A Choti
- , Timothy M Pawlik
- , Hubert D Daniel
- , Rajesh Kannangai
- , G Johan A Offerhaus
- , Victor E Velculescu
- , Linfang Wang
- , Shibin Zhou
- , Bert Vogelstein
- , Ralph H Hruban
- , Nick Papadopoulos
- , Jianqiang Cai
- , Michael S Torbenson
- & Kenneth W Kinzler
Nature Genetics 43 , 828–829

Rights & permissionsfor article Inactivating mutations of the chromatin remodeling gene <i>ARID2</i> in hepatocellular carcinoma . Opens in a new window.
Research | 27 April 2000
CpG methylation is maintained in human cancer cells lacking DNMT1
Nature 404 , 1003–1007

Rights & permissionsfor article CpG methylation is maintained in human cancer cells lacking <i>DNMT1 </i> . Opens in a new window.
Research | 19 March 1998
Mutations of mitotic checkpoint genes in human cancers
Nature 392 , 300–303

Rights & permissionsfor article Mutations of mitotic checkpoint genes in human cancers . Opens in a new window.
Research | 17 September 1992
APC mutations occur early during colorectal tumorigenesis
Nature 359 , 235–237

Rights & permissionsfor article <i>APC</i> mutations occur early during colorectal tumorigenesis . Opens in a new window.
Research | 13 June 2012
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
- Luis A. Diaz Jr
- , Richard T. Williams
- , Jian Wu
- , Isaac Kinde
- , J. Randolph Hecht
- , Jordan Berlin
- , Benjamin Allen
- , Ivana Bozic
- , Johannes G. Reiter
- , Martin A. Nowak
- , Kenneth W. Kinzler
- , Kelly S. Oliner
- & Bert Vogelstein
Nature 486 , 537–540

Rights & permissionsfor article The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers . Opens in a new window.
Reviews | 1 September 2003
The significance of unstable chromosomes in colorectal cancer
Nature Reviews Cancer 3 , 695–701

Rights & permissionsfor article The significance of unstable chromosomes in colorectal cancer . Opens in a new window.
Research | 4 April 2002
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
- Ina Rhee
- , Kurtis E. Bachman
- , Ben Ho Park
- , Kam-Wing Jair
- , Ray-Whay Chiu Yen
- , Kornel E. Schuebel
- , Hengmi Cui
- , Andrew P. Feinberg
- , Christoph Lengauer
- , Kenneth W. Kinzler
- , Stephen B. Baylin
- & Bert Vogelstein
Nature 416 , 552–556

Rights & permissionsfor article DNMT1 and DNMT3b cooperate to silence genes in human cancer cells . Opens in a new window.
Research | 17 February 2000
Conversion of diploidy to haploidy
- Hai Yan
- , Nickolas Papadopoulos
- , Giancarlo Marra
- , Claudia Perrera
- , Josef Jiricny
- , C. Richard Boland
- , Henry T. Lynch
- , Robert B. Chadwick
- , Albert de la Chapelle
- , Karin Berg
- , James R. Eshleman
- , Weishi Yuan
- , Sanford Markowitz
- , Steven J. Laken
- , Christoph Lengauer
- , Kenneth W. Kinzler
- & Bert Vogelstein
Nature 403 , 723–724

Rights & permissionsfor article Conversion of diploidy to haploidy . Opens in a new window.
Correspondence | 1 December 1999
Analysis of human transcriptomes
- Victor E Velculescu
- , Stephen L Madden
- , Lin Zhang
- , Alex E Lash
- , Jian Yu
- , Carlo Rago
- , Anita Lal
- , Clarence J Wang
- , Gary A Beaudry
- , Kristin M Ciriello
- , Brian P Cook
- , Michael R Dufault
- , Anne T Ferguson
- , Yuhong Gao
- , Tong-Chuan He
- , Heiko Hermeking
- , Siewleng K Hiraldo
- , Paul M Hwang
- , Marissa A Lopez
- , Hilary F Luderer
- , Brynna Mathews
- , Joseph M Petroziello
- , Kornelia Polyak
- , Leigh Zawel
- , Wen Zhang
- , Xiaoming Zhang
- , Wei Zhou
- , Frank G Haluska
- , Jin Jen
- , Saraswati Sukumar
- , Gregory M Landes
- , Gregory J Riggins
- , Bert Vogelstein
- & Kenneth W Kinzler
Nature Genetics 23 , 387–388

Rights & permissionsfor article Analysis of human transcriptomes . Opens in a new window.
Research | 1 May 2002
Using the transcriptome to annotate the genome
Nature Biotechnology 20 , 508–512

Rights & permissionsfor article Using the transcriptome to annotate the genome . Opens in a new window.
Research | 1 April 1995
Genetic instability occurs in the majority of young patients with colorectal cancer
- Bo Liu
- , Susan M. Farrington
- , Gloria M. Petersen
- , Stanley R. Hamilton
- , Ramon Parsons
- , Nickolas Papadopoulos
- , Takato Fujiwara
- , Jin Jen
- , Kenneth W. Ainzler
- , Andrew H. Wyllie
- , Bert Vogelstein
- & Malcolm G. Dunlop
Nature Medicine 1 , 348–352

Rights & permissionsfor article Genetic instability occurs in the majority of young patients with colorectal cancer . Opens in a new window.
Research | 23 January 2006
BEAMing up for detection and quantification of rare sequence variants
- Meng Li
- , Frank Diehl
- , Devin Dressman
- , Bert Vogelstein
- & Kenneth W Kinzler
Nature Methods 3 , 95–97

Rights & permissionsfor article BEAMing up for detection and quantification of rare sequence variants . Opens in a new window.
Research | 4 March 2004
Inactivation of hCDC4 can cause chromosomal instability
Nature 428 , 77–81

Rights & permissionsfor article Inactivation of <i>hCDC4</i> can cause chromosomal instability . Opens in a new window.
13 September 1999
CDX2 is mutated in a colorectal cancer with normal APC/β-catenin signaling
- Luis T da Costa
- , Tong-Chuan He
- , Jian Yu
- , Andrew B Sparks
- , Patrice J Morin
- , Kornelia Polyak
- , Steve Laken
- , Bert Vogelstein
- & Kenneth W Kinzler
Oncogene 18 , 5010–5014

Rights & permissionsfor article <i>CDX2</i> is mutated in a colorectal cancer with normal APC/β-catenin signaling . Opens in a new window.
Research | 1 January 1995
Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability
Nature Genetics 9 , 48–55

Rights & permissionsfor article Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability . Opens in a new window.
Research | 1 October 2001
Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells
- Paul M. Hwang
- , Fred Bunz
- , Jian Yu
- , Carlo Rago
- , Timothy A. Chan
- , Michael P. Murphy
- , Geoffry F. Kelso
- , Robin A. J. Smith
- , Kenneth W. Kinzler
- & Bert Vogelstein
Nature Medicine 7 , 1111–1117

Rights & permissionsfor article Ferredoxin reductase affects p53-dependent, 5-fluorouracil–induced apoptosis in colorectal cancer cells . Opens in a new window.
Research | 18 September 1997
A model for p53-induced apoptosis
Nature 389 , 300–305

Rights & permissionsfor article A model for p53-induced apoptosis . Opens in a new window.
Research | 1 October 2001
Use of isogenic human cancer cells for high-throughput screening and drug discovery
Nature Biotechnology 19 , 940–945

Rights & permissionsfor article Use of isogenic human cancer cells for high-throughput screening and drug discovery . Opens in a new window.
Research | 7 December 1989
Mutations in the p53 gene occur in diverse human tumour types
- Janice M. Nigro
- , Suzanne J. Baker
- , Antonette C. Preisinger
- , J. Milburn Jessup
- , Richard Hosteller
- , Karen Cleary
- , Sandra H. Signer
- , Nancy Davidson
- , Stephen Baylin
- , Peter Devilee
- , Thomas Glover
- , Francis S. Collins
- , Ainsley Weslon
- , Rama Modali
- , Curtis C. Harris
- & Bert Vogelstein
Nature 342 , 705–708

Rights & permissionsfor article Mutations in the <i>p53</i> gene occur in diverse human tumour types . Opens in a new window.
Research | 28 November 1985
Loss of genes on the short arm of chromosome 11 in bladder cancer
Nature 318 , 377–380

Rights & permissionsfor article Loss of genes on the short arm of chromosome 11 in bladder cancer . Opens in a new window.
16 November 2000
Surfing the p53 network
Nature 408 , 307–310

Rights & permissionsfor article Surfing the p53 network . Opens in a new window.
Research | 1 November 1998
Somatic mutations of the mitochondrial genome in human colorectal tumours
- Kornelia Polyak
- , Yunbo Li
- , Hong Zhu
- , Christoph Lengauer
- , James K.V. Willson
- , Sanford D. Markowitz
- , Michael A. Trush
- , Kenneth W. Kinzler
- & Bert Vogelstein
Nature Genetics 20 , 291–293

Rights & permissionsfor article Somatic mutations of the mitochondrial genome in human colorectal tumours . Opens in a new window.
Research | 27 February 1992
Clonal expansion of p53 mutant cells is associated with brain tumour progression
Nature 355 , 846–847

Rights & permissionsfor article Clonal expansion of p53 mutant cells is associated with brain tumour progression . Opens in a new window.
Research | 1 April 1992
Definition of a consensus binding site for p53
Nature Genetics 1 , 45–49

Rights & permissionsfor article Definition of a consensus binding site for p53 . Opens in a new window.
1 June 2000
Assessing tumors in living animals through measurement of urinary β-human chorionic gonadotropin
Nature Medicine 6 , 711–714

Rights & permissionsfor article Assessing tumors in living animals through measurement of urinary β-human chorionic gonadotropin . Opens in a new window.
Research | 31 July 2008
Circulating mutant DNA to assess tumor dynamics
- Frank Diehl
- , Kerstin Schmidt
- , Michael A Choti
- , Katharine Romans
- , Steven Goodman
- , Meng Li
- , Katherine Thornton
- , Nishant Agrawal
- , Lori Sokoll
- , Steve A Szabo
- , Kenneth W Kinzler
- , Bert Vogelstein
- & Luis A Diaz Jr
Nature Medicine 14 , 985–990

Rights & permissionsfor article Circulating mutant DNA to assess tumor dynamics . Opens in a new window.
News and Views | 16 January 1992
Carcinogens leave fingerprints
- Bert Vogelstein
- & Kenneth W. Kinzler
Nature 355 , 209–210

Rights & permissionsfor article Carcinogens leave fingerprints . Opens in a new window.
News and Views | 10 June 1993
A gene for neurofibromatosis 2
- Kenneth W. Kinzler
- & Bert Vogelstein
Nature 363 , 495–496

Rights & permissionsfor article A gene for neurofibromatosis 2 . Opens in a new window.
Research | 29 August 2002
RAF/RAS oncogenes and mismatch-repair status
Nature 418 , 934–934

Rights & permissionsfor article <i>RAF</i>/<i>RAS</i> oncogenes and mismatch-repair status . Opens in a new window.
Research | 3 March 2010
Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
Nature 464 , 610–614

Rights & permissionsfor article Heteroplasmic mitochondrial DNA mutations in normal and tumour cells . Opens in a new window.
Research | 1 July 1996
Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers
Nature Genetics 13 , 343–346

Rights & permissionsfor article Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers . Opens in a new window.
Research | 10 August 2005
Mutations in a signalling pathway
- D. Williams Parsons
- , Tian-Li Wang
- , Yardena Samuels
- , Alberto Bardelli
- , Jordan M. Cummins
- , Laura DeLong
- , Natalie Silliman
- , Janine Ptak
- , Steve Szabo
- , James K. V. Willson
- , Sanford Markowitz
- , Kenneth W. Kinzler
- , Bert Vogelstein
- , Christoph Lengauer
- & Victor E. Velculescu
Nature 436 , 792–792

Rights & permissionsfor article Mutations in a signalling pathway . Opens in a new window.
Research | 1 November 1995
Founding mutations and Alu-mediated recombination in hereditary colon cancer
Nature Medicine 1 , 1203–1206

Rights & permissionsfor article Founding mutations and Alu-mediated recombination in hereditary colon cancer . Opens in a new window.
News and Views | 27 December 1990
A deadly inheritance
- Bert Vogelstein
Nature 348 , 681–682

Rights & permissionsfor article A deadly inheritance . Opens in a new window.
Research | 1 September 1995
Monoallelic mutation analysis (MAMA) for identifying germline mutations
Nature Genetics 11 , 99–102

Rights & permissionsfor article Monoallelic mutation analysis (MAMA) for identifying germline mutations . Opens in a new window.

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