nature.com search

Loading Filters

Showing 1–29 of 29 results

Loading Filters

Amendments and Corrections | 16 April 2014
Correction: Corrigendum: Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling
- Wentian Yang
- , Jianguo Wang
- , Douglas C. Moore
- , Haipei Liang
- , Mark Dooner
- , Qian Wu
- , Richard Terek
- , Qian Chen
- , Michael G. Ehrlich
- , Peter J. Quesenberry
- & Benjamin G. Neel
Nature 508 , 420–420

Rights & permissionsfor article Correction: Corrigendum: Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling . Opens in a new window.
Amendments and Corrections | 1 February 2010
Correction: Corrigendum: Neuronal PTP1B regulates body weight, adiposity and leptin action
Nature Medicine 16 , 237–237

Rights & permissionsfor article Correction: Corrigendum: Neuronal PTP1B regulates body weight, adiposity and leptin action . Opens in a new window.
News and Views | 26 October 2016
Bad neighbours cause bad blood
- Gordon Chan
- & Benjamin G. Neel
Nature 539 , 173–175

Rights & permissionsfor article Bad neighbours cause bad blood . Opens in a new window.
News and Views | 1 March 2006
Stops along the RAS pathway in human genetic disease
Nature Medicine 12 , 283–285

Rights & permissionsfor article Stops along the RAS pathway in human genetic disease . Opens in a new window.
Amendments and Corrections | 1 February 2010
Addendum: Neuronal PTP1B regulates body weight, adiposity and leptin action
Nature Medicine 16 , 237–237

Rights & permissionsfor article Addendum: Neuronal PTP1B regulates body weight, adiposity and leptin action . Opens in a new window.
News and Views | 20 November 2003
An eye on organ development
- Jonathan A. Epstein
- & Benjamin G. Neel
Nature 426 , 238–239

Rights & permissionsfor article An eye on organ development . Opens in a new window.
Research | 20 February 2003
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
Nature 421 , 856–859

Rights & permissionsfor article STAT3 signalling is required for leptin regulation of energy balance but not reproduction . Opens in a new window.
Research | 1 March 2000
Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis
- Binbin Chen
- , Roderick T. Bronson
- , Lori D. Klaman
- , Thomas G. Hampton
- , Ju-feng Wang
- , Patricia J. Green
- , Terry Magnuson
- , Pamela S. Douglas
- , James P. Morgan
- & Benjamin G. Neel
Nature Genetics 24 , 296–299

Rights & permissionsfor article Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis . Opens in a new window.
29 July 2002
The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer
- Roger J Daly
- , Haihua Gu
- , Jayamala Parmar
- , Suzann Malaney
- , Ruth J Lyons
- , Rania Kairouz
- , Darren R Head
- , Susan M Henshall
- , Benjamin G Neel
- & Robert L Sutherland
Oncogene 21 , 5175–5181

Rights & permissionsfor article The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer . Opens in a new window.
Research | 10 December 2006
Regulation of protein tyrosine phosphatase 1B by sumoylation
- Shrikrishna Dadke
- , Sophie Cotteret
- , Shu-Chin Yip
- , Zahara M. Jaffer
- , Fawaz Haj
- , Alexey Ivanov
- , Frank Rauscher III
- , Ke Shuai
- , Tony Ng
- , Benjamin G. Neel
- & Jonathan Chernoff
Nature Cell Biology 9 , 80–85

Rights & permissionsfor article Regulation of protein tyrosine phosphatase 1B by sumoylation . Opens in a new window.
Research | 3 December 2006
Germline gain-of-function mutations in SOS1 cause Noonan syndrome
- Amy E Roberts
- , Toshiyuki Araki
- , Kenneth D Swanson
- , Kate T Montgomery
- , Taryn A Schiripo
- , Victoria A Joshi
- , Li Li
- , Yosuf Yassin
- , Alex M Tamburino
- , Benjamin G Neel
- & Raju S Kucherlapati
Nature Genetics 39 , 70–74

Rights & permissionsfor article Germline gain-of-function mutations in SOS1 cause Noonan syndrome . Opens in a new window.
Research | 12 July 2001
Essential role for Gab2 in the allergic response
- Haihua Gu
- , Kan Saito
- , Lori D. Klaman
- , Junqing Shen
- , Tony Fleming
- , YongPing Wang
- , Joanne C. Pratt
- , Guosheng Lin
- , Bing Lim
- , Jean-Pierre Kinet
- & Benjamin G. Neel
Nature 412 , 186–190

Rights & permissionsfor article Essential role for Gab2 in the allergic response . Opens in a new window.
Research | 23 July 1992
Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21
Nature 358 , 351–354

Rights & permissionsfor article Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21 . Opens in a new window.
Research | 26 November 2019 | Open
Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma
- Shuang Zhang
- , Igor Dolgalev
- , Tao Zhang
- , Hao Ran
- , Douglas A. Levine
- & Benjamin G. Neel
Nature Communications 10 , 1–16

Rights & permissionsfor article Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma . Opens in a new window.
Research | 29 July 2019 | Open
Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival
Scientific Reports 9 , 1–12

Rights & permissionsfor article Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival . Opens in a new window.
Research | 22 April 2019
An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity
Nature Medicine 25 , 838–849

Rights & permissionsfor article An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity . Opens in a new window.
Research | 6 April 2018 | Open
SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity
- Chunlin Zuo
- , Lijun Wang
- , Raghavendra M. Kamalesh
- , Margot E. Bowen
- , Douglas C. Moore
- , Mark S. Dooner
- , Anthony M. Reginato
- , Qian Wu
- , Christoph Schorl
- , Yueming Song
- , Matthew L. Warman
- , Benjamin G. Neel
- , Michael G. Ehrlich
- & Wentian Yang
Bone Research 6 , 1–13

Rights & permissionsfor article SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity . Opens in a new window.
Research | 26 May 2017 | Open
Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome
- Jiani C. Yin
- , Mathew J. Platt
- , Xixi Tian
- , Xue Wu
- , Peter H. Backx
- , Jeremy A. Simpson
- , Toshiyuki Araki
- & Benjamin G. Neel
Nature Communications 8 , 1–11

Rights & permissionsfor article Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome . Opens in a new window.
Research | 6 September 2017 | Open
Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2
Nature Communications 8 , 1–14

Rights & permissionsfor article Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2 . Opens in a new window.
Research | 20 June 2016
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia
- Robert S. Banh
- , Caterina Iorio
- , Richard Marcotte
- , Yang Xu
- , Dan Cojocari
- , Anas Abdel Rahman
- , Judy Pawling
- , Wei Zhang
- , Ankit Sinha
- , Christopher M. Rose
- , Marta Isasa
- , Shuang Zhang
- , Ronald Wu
- , Carl Virtanen
- , Toshiaki Hitomi
- , Toshiyuki Habu
- , Sachdev S. Sidhu
- , Akio Koizumi
- , Sarah E. Wilkins
- , Thomas Kislinger
- , Steven P. Gygi
- , Christopher J. Schofield
- , James W. Dennis
- , Bradly G. Wouters
- & Benjamin G. Neel
Nature Cell Biology 18 , 803–813

Rights & permissionsfor article PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia . Opens in a new window.
Research | 2 September 2015
The spliceosome is a therapeutic vulnerability in MYC-driven cancer
- Tiffany Y.-T. Hsu
- , Lukas M. Simon
- , Nicholas J. Neill
- , Richard Marcotte
- , Azin Sayad
- , Christopher S. Bland
- , Gloria V. Echeverria
- , Tingting Sun
- , Sarah J. Kurley
- , Siddhartha Tyagi
- , Kristen L. Karlin
- , Rocio Dominguez-Vidaña
- , Jessica D. Hartman
- , Alexander Renwick
- , Kathleen Scorsone
- , Ronald J. Bernardi
- , Samuel O. Skinner
- , Antrix Jain
- , Mayra Orellana
- , Chandraiah Lagisetti
- , Ido Golding
- , Sung Y. Jung
- , Joel R. Neilson
- , Xiang H.-F. Zhang
- , Thomas A. Cooper
- , Thomas R. Webb
- , Benjamin G. Neel
- , Chad A. Shaw
- & Thomas F. Westbrook
Nature 525 , 384–388

Rights & permissionsfor article The spliceosome is a therapeutic vulnerability in MYC-driven cancer . Opens in a new window.
Research | 10 November 2014
Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome
- Yong-Seok Lee
- , Dan Ehninger
- , Miou Zhou
- , Jun-Young Oh
- , Minkyung Kang
- , Chuljung Kwak
- , Hyun-Hee Ryu
- , Delana Butz
- , Toshiyuki Araki
- , Ying Cai
- , J Balaji
- , Yoshitake Sano
- , Christine I Nam
- , Hyong Kyu Kim
- , Bong-Kiun Kaang
- , Corinna Burger
- , Benjamin G Neel
- & Alcino J Silva
Nature Neuroscience 17 , 1736–1743

Rights & permissionsfor article Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome . Opens in a new window.
Research | 24 June 2013
Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2
- Jie Sun
- , Shaoying Lu
- , Mingxing Ouyang
- , Li-Jung Lin
- , Yue Zhuo
- , Bo Liu
- , Shu Chien
- , Benjamin G. Neel
- & Yingxiao Wang
Nature Communications 4 , 1–11

Rights & permissionsfor article Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2 . Opens in a new window.
Research | 17 July 2013
Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling
- Wentian Yang
- , Jianguo Wang
- , Douglas C. Moore
- , Haipei Liang
- , Mark Dooner
- , Qian Wu
- , Richard Terek
- , Qian Chen
- , Michael G. Ehrlich
- , Peter J. Quesenberry
- & Benjamin G. Neel
Nature 499 , 491–495

Rights & permissionsfor article Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling . Opens in a new window.
Research | 25 July 2004
Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutation
- Toshiyuki Araki
- , M Golam Mohi
- , Fraz A Ismat
- , Roderick T Bronson
- , Ifor R Williams
- , Jeffery L Kutok
- , Wentian Yang
- , Lily I Pao
- , D Gary Gilliland
- , Jonathan A Epstein
- & Benjamin G Neel
Nature Medicine 10 , 849–857

Rights & permissionsfor article Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutation . Opens in a new window.
Research | 9 May 2004
CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity
- Jie Chen
- , Paul A McLean
- , Benjamin G Neel
- , Gbolahan Okunade
- , Gary E Shull
- & Henry H Wortis
Nature Immunology 5 , 651–657

Rights & permissionsfor article CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity . Opens in a new window.
Research | 16 July 2006
Neuronal PTP1B regulates body weight, adiposity and leptin action
Nature Medicine 12 , 917–924

Rights & permissionsfor article Neuronal PTP1B regulates body weight, adiposity and leptin action . Opens in a new window.
Research | 20 December 2005
A role for the scaffolding adapter GAB2 in breast cancer
- Mohamed Bentires-Alj
- , Susana G Gil
- , Richard Chan
- , Zhigang C Wang
- , Yongping Wang
- , Naoko Imanaka
- , Lyndsay N Harris
- , Andrea Richardson
- , Benjamin G Neel
- & Haihua Gu
Nature Medicine 12 , 114–121

Rights & permissionsfor article A role for the scaffolding adapter GAB2 in breast cancer . Opens in a new window.
Research | 9 April 1981
Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis
Nature 290 , 475–480

Rights & permissionsfor article Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis . Opens in a new window.

Refine your results by…

Filters

Filter By:

Correction: Corrigendum: Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling

Correction: Corrigendum: Neuronal PTP1B regulates body weight, adiposity and leptin action

Bad neighbours cause bad blood

Stops along the RAS pathway in human genetic disease

Addendum: Neuronal PTP1B regulates body weight, adiposity and leptin action

An eye on organ development

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

Mice mutant for Egfr and Shp2 have defective cardiac semilunar valvulogenesis

The docking protein Gab2 is overexpressed and estrogen regulated in human breast cancer

Regulation of protein tyrosine phosphatase 1B by sumoylation

Germline gain-of-function mutations in SOS1 cause Noonan syndrome

Essential role for Gab2 in the allergic response

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity

Cellular interplay via cytokine hierarchy causes pathological cardiac hypertrophy in RAF1-mutant Noonan syndrome

Assay to visualize specific protein oxidation reveals spatio-temporal regulation of SHP2

PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

The spliceosome is a therapeutic vulnerability in MYC-driven cancer

Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome

Antagonism between binding site affinity and conformational dynamics tunes alternative cis-interactions within Shp2

Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling

Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutation

CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity

Neuronal PTP1B regulates body weight, adiposity and leptin action

A role for the scaffolding adapter GAB2 in breast cancer

Activation of a cellular onc gene by promoter insertion in ALV-induced lymphoid leukosis

Quick links

Refine your results by…

Filters ​

Filter By:

Search

Quick links

Filters