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Research | 24 September 2020
Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer
- Tong Gan
- , Ashley T. Stevens
- , Xiaopeng Xiong
- , Yang-An Wen
- , Trevor N. Farmer
- , Austin T. Li
- , Payton D. Stevens
- , Sanam Golshani
- , Heidi L. Weiss
- , B. Mark Evers
- & Tianyan Gao
Oncogene 39 , 6789–6801

Rights & permissionsfor article Inhibition of protein tyrosine phosphatase receptor type F suppresses Wnt signaling in colorectal cancer . Opens in a new window.
Research | 10 September 2020 | Open
Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer
Cell Death & Disease 11 , 1–16

Rights & permissionsfor article Upregulation of CPT1A is essential for the tumor-promoting effect of adipocytes in colon cancer . Opens in a new window.
News and Views | 15 February 2017
A new innate immune sensor — functions from inside the colonic epithelium
- Tianyan Gao
- & B. Mark Evers
Nature Reviews Gastroenterology & Hepatology 14 , 199–200

Rights & permissionsfor article A new innate immune sensor — functions from inside the colonic epithelium . Opens in a new window.
Research | 26 June 2020 | Open
Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression
- Yubin Guo
- , Qing Ye
- , Pan Deng
- , Yanan Cao
- , Daheng He
- , Zhaohe Zhou
- , Chi Wang
- , Yekaterina Y. Zaytseva
- , Charles E. Schwartz
- , Eun Y. Lee
- , B. Mark Evers
- , Andrew J. Morris
- , Side Liu
- & Qing-Bai She
Nature Communications 11 , 1–16

Rights & permissionsfor article Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression . Opens in a new window.
Research | 20 February 2020 | Open
Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy
- Sijin Guo
- , Mario Vieweger
- , Kaiming Zhang
- , Hongran Yin
- , Hongzhi Wang
- , Xin Li
- , Shanshan Li
- , Shuiying Hu
- , Alex Sparreboom
- , B. Mark Evers
- , Yizhou Dong
- , Wah Chiu
- & Peixuan Guo
Nature Communications 11 , 1–11

Rights & permissionsfor article Ultra-thermostable RNA nanoparticles for solubilizing and high-yield loading of paclitaxel for breast cancer therapy . Opens in a new window.
Research | 13 April 2007
Upregulation and redistribution of integrin α6β4 expression occurs at an early stage in pancreatic adenocarcinoma progression
Modern Pathology 20 , 656–667

Rights & permissionsfor article Upregulation and redistribution of integrin α6β4 expression occurs at an early stage in pancreatic adenocarcinoma progression . Opens in a new window.
Research | 1 December 2005
Signal Transduction Pathways Involved in Oxidative Stress-Induced Intestinal Epithelial Cell Apoptosis
- Yuning Zhou
- , Qingding Wang
- , B Mark Evers
- & Dai H Chung
Pediatric Research 58 , 1192–1197

Rights & permissionsfor article Signal Transduction Pathways Involved in Oxidative Stress-Induced Intestinal Epithelial Cell Apoptosis . Opens in a new window.
Research | 15 February 2017 | Open
Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation
- Yadi Wu
- , Yu Wang
- , Yiwei Lin
- , Yajuan Liu
- , Yifan Wang
- , Jianhang Jia
- , Puja Singh
- , Young-In Chi
- , Chi Wang
- , Chenfang Dong
- , Wei Li
- , Min Tao
- , Dana Napier
- , Qiuying Shi
- , Jiong Deng
- , B Mark Evers
- & Binhua P. Zhou
Nature Communications 8 , 1–16

Rights & permissionsfor article Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation . Opens in a new window.
Research | 2 February 2017 | Open
Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer
- Yang-An Wen
- , Xiaopeng Xing
- , Jennifer W Harris
- , Yekaterina Y Zaytseva
- , Mihail I Mitov
- , Dana L Napier
- , Heidi L Weiss
- , B Mark Evers
- & Tianyan Gao
Cell Death & Disease 8 , e2593–e2593

Rights & permissionsfor article Adipocytes activate mitochondrial fatty acid oxidation and autophagy to promote tumor growth in colon cancer . Opens in a new window.
Research | 5 December 2018 | Open
Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer
- Jingyi Liu
- , Zhibing Duan
- , Weijie Guo
- , Lei Zeng
- , Yadi Wu
- , Yule Chen
- , Fang Tai
- , Yifan Wang
- , Yiwei Lin
- , Qiang Zhang
- , Yanling He
- , Jiong Deng
- , Rachel L. Stewart
- , Chi Wang
- , Pengnian Charles Lin
- , Saghi Ghaffari
- , B. Mark Evers
- , Suling Liu
- , Ming-Ming Zhou
- , Binhua P. Zhou
- & Jian Shi
Nature Communications 9 , 1–17

Rights & permissionsfor article Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer . Opens in a new window.
Research | 15 February 2018 | Open
Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer
- Yang-An Wen
- , Xiaopeng Xiong
- , Yekaterina Y. Zaytseva
- , Dana L. Napier
- , Emma Vallee
- , Austin T. Li
- , Chi Wang
- , Heidi L. Weiss
- , B. Mark Evers
- & Tianyan Gao
Cell Death & Disease 9 , 1–14

Rights & permissionsfor article Downregulation of SREBP inhibits tumor growth and initiation by altering cellular metabolism in colon cancer . Opens in a new window.
Research | 11 December 2017
Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression
- Fengmei Pi
- , Daniel W. Binzel
- , Tae Jin Lee
- , Zhefeng Li
- , Meiyan Sun
- , Piotr Rychahou
- , Hui Li
- , Farzin Haque
- , Shaoying Wang
- , Carlo M. Croce
- , Bin Guo
- , B. Mark Evers
- & Peixuan Guo
Nature Nanotechnology 13 , 82–89

Rights & permissionsfor article Nanoparticle orientation to control RNA loading and ligand display on extracellular vesicles for cancer regression . Opens in a new window.
Research | 20 December 2017 | Open
Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1
- Jun Wang
- , Qing Ye
- , Yanan Cao
- , Yubin Guo
- , Xiuping Huang
- , Wenting Mi
- , Side Liu
- , Chi Wang
- , Hsin-Sheng Yang
- , Binhua P. Zhou
- , B. Mark Evers
- & Qing-Bai She
Nature Communications 8 , 1–15

Rights & permissionsfor article Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1 . Opens in a new window.
Research | 11 May 2016
An obligatory role for neurotensin in high-fat-diet-induced obesity
- Jing Li
- , Jun Song
- , Yekaterina Y. Zaytseva
- , Yajuan Liu
- , Piotr Rychahou
- , Kai Jiang
- , Marlene E. Starr
- , Ji Tae Kim
- , Jennifer W. Harris
- , Frederique B. Yiannikouris
- , Wendy S. Katz
- , Peter M. Nilsson
- , Marju Orho-Melander
- , Jing Chen
- , Haining Zhu
- , Timothy Fahrenholz
- , Richard M. Higashi
- , Tianyan Gao
- , Andrew J. Morris
- , Lisa A. Cassis
- , Teresa W. -M. Fan
- , Heidi L. Weiss
- , Paul R. Dobner
- , Olle Melander
- , Jianhang Jia
- & B. Mark Evers
Nature 533 , 411–415

Rights & permissionsfor article An obligatory role for neurotensin in high-fat-diet-induced obesity . Opens in a new window.
9 December 2016
Ketogenesis contributes to intestinal cell differentiation
- Qingding Wang
- , Yuning Zhou
- , Piotr Rychahou
- , Teresa W-M Fan
- , Andrew N Lane
- , Heidi L Weiss
- & B Mark Evers
Cell Death and Differentiation 24 , 458–468

Rights & permissionsfor article Ketogenesis contributes to intestinal cell differentiation . Opens in a new window.
23 February 2004
Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-κB-dependent pathway
- Xiaofu Wang
- , Qingding Wang
- , Wanqin Hu
- & B Mark Evers
Oncogene 23 , 1885–1895

Rights & permissionsfor article Regulation of phorbol ester-mediated TRAF1 induction in human colon cancer cells through a PKC/RAF/ERK/NF-κB-dependent pathway . Opens in a new window.

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