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Showing 1–14 of 14 results

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Research | 26 February 2020 | Open
The role of Mediator and Little Elongation Complex in transcription termination
- Hidehisa Takahashi
- , Amol Ranjan
- , Shiyuan Chen
- , Hidefumi Suzuki
- , Mio Shibata
- , Tomonori Hirose
- , Hiroko Hirose
- , Kazunori Sasaki
- , Ryota Abe
- , Kai Chen
- , Yanfeng He
- , Ying Zhang
- , Ichigaku Takigawa
- , Tadasuke Tsukiyama
- , Masashi Watanabe
- , Satoshi Fujii
- , Midori Iida
- , Junichi Yamamoto
- , Yuki Yamaguchi
- , Yutaka Suzuki
- , Masaki Matsumoto
- , Keiichi I. Nakayama
- , Michael P. Washburn
- , Anita Saraf
- , Laurence Florens
- , Shigeo Sato
- , Chieri Tomomori-Sato
- , Ronald C. Conaway
- , Joan W. Conaway
- & Shigetsugu Hatakeyama
Nature Communications 11 , 1–20

Rights & permissionsfor article The role of Mediator and Little Elongation Complex in transcription termination . Opens in a new window.
Research | 20 October 2010
Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
- Norman Pavelka
- , Giulia Rancati
- , Jin Zhu
- , William D. Bradford
- , Anita Saraf
- , Laurence Florens
- , Brian W. Sanderson
- , Gaye L. Hattem
- & Rong Li
Nature 468 , 321–325

Rights & permissionsfor article Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast . Opens in a new window.
Research | 1 July 2010
SCF^{Cyclin F} controls centrosome homeostasis and mitotic fidelity through CP110 degradation
Nature 466 , 138–142

Rights & permissionsfor article SCF<sup>Cyclin F</sup> controls centrosome homeostasis and mitotic fidelity through CP110 degradation . Opens in a new window.
Reviews | 19 December 2019 | Open
Mitochondrial dysfunction and oxidative stress in heart disease
Experimental & Molecular Medicine 51 , 1–13

Rights & permissionsfor article Mitochondrial dysfunction and oxidative stress in heart disease . Opens in a new window.
Research | 12 August 2019
The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation
- Maria Guillamot
- , Dahmane Ouazia
- , Igor Dolgalev
- , Stephen T. Yeung
- , Nikos Kourtis
- , Yuling Dai
- , Kate Corrigan
- , Luna Zea-Redondo
- , Anita Saraf
- , Laurence Florens
- , Michael P. Washburn
- , Anastasia N. Tikhonova
- , Marina Malumbres
- , Yixiao Gong
- , Aristotelis Tsirigos
- , Christopher Park
- , Christopher Barbieri
- , Kamal M. Khanna
- , Luca Busino
- & Iannis Aifantis
Nature Immunology 20 , 1196–1207

Rights & permissionsfor article The E3 ubiquitin ligase SPOP controls resolution of systemic inflammation by triggering MYD88 degradation . Opens in a new window.
Research | 13 February 2019 | Open
RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation
- Nan Zhou
- , Alvaro Gutierrez-Uzquiza
- , Xiang Yu Zheng
- , Renxu Chang
- , Dan T. Vogl
- , Alfred L. Garfall
- , Luca Bernabei
- , Anita Saraf
- , Laurence Florens
- , Michael P. Washburn
- , Anuradha Illendula
- , John H. Bushweller
- & Luca Busino
Leukemia 33 , 2006–2021

Rights & permissionsfor article RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation . Opens in a new window.
Research | 25 April 2018
Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2
- Jaewoo Choi
- , Kyutae Lee
- , Kristin Ingvarsdottir
- , Roberto Bonasio
- , Anita Saraf
- , Laurence Florens
- , Michael P. Washburn
- , Saber Tadros
- , Michael R. Green
- & Luca Busino
Nature Cell Biology 20 , 586–596

Rights & permissionsfor article Loss of KLHL6 promotes diffuse large B-cell lymphoma growth and survival by stabilizing the mRNA decay factor roquin2 . Opens in a new window.
Research | 14 June 2017
PTEN counteracts FBXL2 to promote IP3R3- and Ca²⁺-mediated apoptosis limiting tumour growth
- Shafi Kuchay
- , Carlotta Giorgi
- , Daniele Simoneschi
- , Julia Pagan
- , Sonia Missiroli
- , Anita Saraf
- , Laurence Florens
- , Michael P. Washburn
- , Ana Collazo-Lorduy
- , Mireia Castillo-Martin
- , Carlos Cordon-Cardo
- , Said M. Sebti
- , Paolo Pinton
- & Michele Pagano
Nature 546 , 554–558

Rights & permissionsfor article PTEN counteracts FBXL2 to promote IP3R3- and Ca<sup>2+</sup>-mediated apoptosis limiting tumour growth . Opens in a new window.
Research | 28 September 2017 | Open
The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry
Nature Communications 8 , 1–13

Rights & permissionsfor article The WHHERE coactivator complex is required for retinoic acid-dependent regulation of embryonic symmetry . Opens in a new window.
Research | 20 March 2017
The TDH–GCN5L1–Fbxo15–KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells
- Valerio Donato
- , Massimo Bonora
- , Daniele Simoneschi
- , Davide Sartini
- , Yasusei Kudo
- , Anita Saraf
- , Laurence Florens
- , Michael P. Washburn
- , Matthias Stadtfeld
- , Paolo Pinton
- & Michele Pagano
Nature Cell Biology 19 , 341–351

Rights & permissionsfor article The TDH–GCN5L1–Fbxo15–KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells . Opens in a new window.
Research | 21 April 2013
FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade
- Shafi Kuchay
- , Shanshan Duan
- , Emily Schenkein
- , Angelo Peschiaroli
- , Anita Saraf
- , Laurence Florens
- , Michael P. Washburn
- & Michele Pagano
Nature Cell Biology 15 , 472–480

Rights & permissionsfor article FBXL2- and PTPL1-mediated degradation of p110-free p85β regulatory subunit controls the PI(3)K signalling cascade . Opens in a new window.
Research | 13 February 2015 | Open
The Integrator complex controls the termination of transcription at diverse classes of gene targets
- Jeffrey R Skaar
- , Andrea L Ferris
- , Xiaolin Wu
- , Anita Saraf
- , Kum Kum Khanna
- , Laurence Florens
- , Michael P Washburn
- , Stephen H Hughes
- & Michele Pagano
Cell Research 25 , 288–305

Rights & permissionsfor article The Integrator complex controls the termination of transcription at diverse classes of gene targets . Opens in a new window.
Research | 15 December 2014
Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing
Nature Cell Biology 17 , 31–43

Rights & permissionsfor article Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing . Opens in a new window.
Research | 22 June 2015
TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin
Nature Communications 6 , 1–13

Rights & permissionsfor article TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin . Opens in a new window.

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