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Research | 2 November 2020 | Open
Use of machine learning to classify adult ADHD and other conditions based on the Conners’ Adult ADHD Rating Scales
Scientific Reports 10 , 1–10

Rights & permissionsfor article Use of machine learning to classify adult ADHD and other conditions based on the Conners’ Adult ADHD Rating Scales . Opens in a new window.
Research | 1 October 1995
Mouse models of Tay–Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism
Nature Genetics 11 , 170–176

Rights & permissionsfor article Mouse models of Tay–Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism . Opens in a new window.
Research | 1 November 1996
Mice lacking both subunits of lysosomal β–hexosaminidase display gangliosidosis and mucopolysaccharidosis
Nature Genetics 14 , 348–352

Rights & permissionsfor article Mice lacking both subunits of lysosomal β–hexosaminidase display gangliosidosis and mucopolysaccharidosis . Opens in a new window.
18 July 2005
Immortalized fibroblasts from NF-κB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor α after transformation by v-Ras
Oncogene 24 , 6574–6583

Rights & permissionsfor article Immortalized fibroblasts from NF-κB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor α after transformation by v-Ras . Opens in a new window.
Research | 5 December 1991
Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE
Nature 354 , 398–401

Rights & permissionsfor article Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE . Opens in a new window.
Research | 28 March 1996
A histone octamer-like structure within TFIID
Nature 380 , 356–359

Rights & permissionsfor article A histone octamer-like structure within TFIID . Opens in a new window.
Research | 26 July 1990
Arabidopsis thaliana contains two genes for TFIID
Nature 346 , 390–394

Rights & permissionsfor article Arabidopsis thaliana contains two genes for TFIID . Opens in a new window.
Research | 26 July 1990
Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)
- Alexander Hoffmann
- , Eric Sinn
- , Tohru Yamamoto
- , Josephine Wang
- , Ananda Roy
- , Masami Horikoshi
- & Robert G. Roeder
Nature 346 , 387–390

Rights & permissionsfor article Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID) . Opens in a new window.
Research | 1 January 2001
Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event
Nature Immunology 2 , 51–57

Rights & permissionsfor article Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event . Opens in a new window.
Research | 26 August 2010
IκBβ acts to inhibit and activate gene expression during the inflammatory response
- Ping Rao
- , Mathew S. Hayden
- , Meixiao Long
- , Martin L. Scott
- , A. Philip West
- , Dekai Zhang
- , Andrea Oeckinghaus
- , Candace Lynch
- , Alexander Hoffmann
- , David Baltimore
- & Sankar Ghosh
Nature 466 , 1115–1119

Rights & permissionsfor article IκBβ acts to inhibit and activate gene expression during the inflammatory response . Opens in a new window.
Research | 27 March 2019 | Open
Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions
- Quen Cheng
- , Faraz Behzadi
- , Supriya Sen
- , Sho Ohta
- , Roberto Spreafico
- , Rosane Teles
- , Robert L. Modlin
- & Alexander Hoffmann
Scientific Reports 9 , 1–14

Rights & permissionsfor article Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions . Opens in a new window.
Research | 20 October 2016 | Open
Oscillation dynamics underlie functional switching of NF-κB for B-cell activation
npj Systems Biology and Applications 2 , 1–9

Rights & permissionsfor article Oscillation dynamics underlie functional switching of NF-κB for B-cell activation . Opens in a new window.
Research | 22 February 2016 | Open
The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis
- Jinjin Xu
- , Lei Zhou
- , Lei Ji
- , Fengyuan Chen
- , Karen Fortmann
- , Kun Zhang
- , Qingwu Liu
- , Ke Li
- , Weicang Wang
- , Hao Wang
- , Wei Xie
- , Qingwei Wang
- , Jiang Liu
- , Biao Zheng
- , Pei Zhang
- , Shixia Huang
- , Tieliu Shi
- , Biaohong Zhang
- , Yongyan Dang
- , Jiwu Chen
- , Bert W. O’Malley
- , Robb E. Moses
- , Ping Wang
- , Lei Li
- , Jianru Xiao
- , Alexander Hoffmann
- & Xiaotao Li
Nature Communications 7 , 1–14

Rights & permissionsfor article The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis . Opens in a new window.
Research | 7 May 2015
IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer
- Rachel Tsui
- , Jeffrey D. Kearns
- , Candace Lynch
- , Don Vu
- , Kim A. Ngo
- , Soumen Basak
- , Gourisankar Ghosh
- & Alexander Hoffmann
Nature Communications 6 , 1–10

Rights & permissionsfor article IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer . Opens in a new window.
Research | 4 March 2012
Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma
Nature Cell Biology 14 , 375–385

Rights & permissionsfor article Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma . Opens in a new window.
Research | 21 October 2012
Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways
- Vincent F-S Shih
- , Jeremy Davis-Turak
- , Monica Macal
- , Jenny Q Huang
- , Julia Ponomarenko
- , Jeffrey D Kearns
- , Tony Yu
- , Riku Fagerlund
- , Masataka Asagiri
- , Elina I Zuniga
- & Alexander Hoffmann
Nature Immunology 13 , 1162–1170

Rights & permissionsfor article Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways . Opens in a new window.
23 November 2010
A single NFκB system for both canonical and non-canonical signaling
Cell Research 21 , 86–102

Rights & permissionsfor article A single NFκB system for both canonical and non-canonical signaling . Opens in a new window.
Research | 5 November 1992
Crystal structure of TFIID TATA-box binding protein
- Dimitar B. Nikolov
- , Shu-Hong Hu
- , Judith Lin
- , Alexander Gasch
- , Alexander Hoffmann
- , Masami Horikoshi
- , Nam-Hai Chua
- , Robert G. Roeder
- & Stephen K. Burley
Nature 360 , 40–46

Rights & permissionsfor article Crystal structure of TFIID TATA-box binding protein . Opens in a new window.
Research | 28 March 1996
Structural similarity between TAFs and the heterotetrameric core of the histone octamer
Nature 380 , 316–322

Rights & permissionsfor article Structural similarity between TAFs and the heterotetrameric core of the histone octamer . Opens in a new window.

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Use of machine learning to classify adult ADHD and other conditions based on the Conners’ Adult ADHD Rating Scales

Mouse models of Tay–Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

Mice lacking both subunits of lysosomal β–hexosaminidase display gangliosidosis and mucopolysaccharidosis

Immortalized fibroblasts from NF-κB RelA knockout mice show phenotypic heterogeneity and maintain increased sensitivity to tumor necrosis factor α after transformation by v-Ras

Structural motifs and potential a homologies in the large subunit of human general transcription factor TFIIE

A histone octamer-like structure within TFIID

Arabidopsis thaliana contains two genes for TFIID

Highly conserved core domain and unique N terminus with presumptive regulatory motifs in a human TATA factor (TFIID)

Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Rel-independent event

IκBβ acts to inhibit and activate gene expression during the inflammatory response

Sequential conditioning-stimulation reveals distinct gene- and stimulus-specific effects of Type I and II IFN on human macrophage functions

Oscillation dynamics underlie functional switching of NF-κB for B-cell activation

The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis

IκBβ enhances the generation of the low-affinity NFκB/RelA homodimer

Fbxw7α- and GSK3-mediated degradation of p100 is a pro-survival mechanism in multiple myeloma

Control of RelB during dendritic cell activation integrates canonical and noncanonical NF-κB pathways

A single NFκB system for both canonical and non-canonical signaling

Crystal structure of TFIID TATA-box binding protein

Structural similarity between TAFs and the heterotetrameric core of the histone octamer

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