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Research | 24 August 2020
The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation
- Susanna S. Ng
- , Fabian De Labastida Rivera
- , Juming Yan
- , Dillon Corvino
- , Indrajit Das
- , Ping Zhang
- , Rachel Kuns
- , Shashi Bhushan Chauhan
- , Jiajie Hou
- , Xian-Yang Li
- , Teija C. M. Frame
- , Benjamin A. McEnroe
- , Eilish Moore
- , Jinrui Na
- , Jessica A. Engel
- , Megan S. F. Soon
- , Bhawana Singh
- , Andrew J. Kueh
- , Marco J. Herold
- , Marcela Montes de Oca
- , Siddharth Sankar Singh
- , Patrick T. Bunn
- , Amy Roman Aguilera
- , Mika Casey
- , Matthias Braun
- , Nazanin Ghazanfari
- , Shivangi Wani
- , Yulin Wang
- , Fiona H. Amante
- , Chelsea L. Edwards
- , Ashraful Haque
- , William C. Dougall
- , Om Prakash Singh
- , Alan G. Baxter
- , Michele W. L. Teng
- , Alex Loukas
- , Norelle L. Daly
- , Nicole Cloonan
- , Mariapia A. Degli-Esposti
- , Jude Uzonna
- , William R. Heath
- , Tobias Bald
- , Siok-Keen Tey
- , Kyohei Nakamura
- , Geoffrey R. Hill
- , Rajiv Kumar
- , Shyam Sundar
- , Mark J. Smyth
- & Christian R. Engwerda
Nature Immunology 21 , 1205–1218

Rights & permissionsfor article The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation . Opens in a new window.
Research | 9 November 2016 | Open
Changes in duodenal tissue-associated microbiota following hookworm infection and consecutive gluten challenges in humans with coeliac disease
- Paul Giacomin
- , Martha Zakrzewski
- , Timothy P. Jenkins
- , Xiaopei Su
- , Rafid Al-Hallaf
- , John Croese
- , Stefan de Vries
- , Andrew Grant
- , Makedonka Mitreva
- , Alex Loukas
- , Lutz Krause
- & Cinzia Cantacessi
Scientific Reports 6 , 1–10

Rights & permissionsfor article Changes in duodenal tissue-associated microbiota following hookworm infection and consecutive gluten challenges in humans with coeliac disease . Opens in a new window.
Research | 4 August 2015 | Open
Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis
Scientific Reports 5 , 1–10

Rights & permissionsfor article Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis . Opens in a new window.
Research | 18 September 2015 | Open
Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects
- Paul Giacomin
- , Martha Zakrzewski
- , John Croese
- , Xiaopei Su
- , Javier Sotillo
- , Leisa McCann
- , Severine Navarro
- , Makedonka Mitreva
- , Lutz Krause
- , Alex Loukas
- & Cinzia Cantacessi
Scientific Reports 5 , 1–8

Rights & permissionsfor article Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects . Opens in a new window.
News and Views | 1 April 2008
New drugs for an ancient parasite
- Alex Loukas
- & Jeffrey M Bethony
Nature Medicine 14 , 365–367

Rights & permissionsfor article New drugs for an ancient parasite . Opens in a new window.
Research | 18 June 2006
Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis
- Mai H Tran
- , Mark S Pearson
- , Jeffrey M Bethony
- , Danielle J Smyth
- , Malcolm K Jones
- , Mary Duke
- , Tegan A Don
- , Donald P McManus
- , Rodrigo Correa-Oliveira
- & Alex Loukas
Nature Medicine 12 , 835–840

Rights & permissionsfor article Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis . Opens in a new window.
Research | 30 October 2017 | Open
Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes
- Sujittra Chaiyadet
- , Watchara Krueajampa
- , Wiphawi Hipkaeo
- , Yada Plosan
- , Supawadee Piratae
- , Javier Sotillo
- , Michael Smout
- , Banchob Sripa
- , Paul J. Brindley
- , Alex Loukas
- & Thewarach Laha
Scientific Reports 7 , 1–12

Rights & permissionsfor article Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes . Opens in a new window.
Research | 17 January 2018 | Open
Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing
- Janis C. Weeks
- , William M. Roberts
- , Caitlyn Leasure
- , Brian M. Suzuki
- , Kristin J. Robinson
- , Heather Currey
- , Phurpa Wangchuk
- , Ramon M. Eichenberger
- , Aleen D. Saxton
- , Thomas D. Bird
- , Brian C. Kraemer
- , Alex Loukas
- , John M. Hawdon
- , Conor R. Caffrey
- & Nicole F. Liachko
Scientific Reports 8 , 1–17

Rights & permissionsfor article Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing . Opens in a new window.
Research | 15 February 2017 | Open
Elevated prevalence of Helicobacter species and virulence factors in opisthorchiasis and associated hepatobiliary disease
Scientific Reports 7 , 1–11

Rights & permissionsfor article Elevated prevalence of Helicobacter species and virulence factors in opisthorchiasis and associated hepatobiliary disease . Opens in a new window.
Reviews | 8 December 2016
Hookworm infection
Nature Reviews Disease Primers 2 , 1–18

Rights & permissionsfor article Hookworm infection . Opens in a new window.
Research | 30 August 2016 | Open
Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms
Scientific Reports 6 , 1–10

Rights & permissionsfor article Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms . Opens in a new window.
Research | 13 February 2017 | Open
Changes in protein expression after treatment with Ancylostoma caninum excretory/secretory products in a mouse model of colitis
- Javier Sotillo
- , Ivana Ferreira
- , Jeremy Potriquet
- , Thewarach Laha
- , Severine Navarro
- , Alex Loukas
- & Jason Mulvenna
Scientific Reports 7 , 1–11

Rights & permissionsfor article Changes in protein expression after treatment with Ancylostoma caninum excretory/secretory products in a mouse model of colitis . Opens in a new window.
Research | 11 October 2013 | Open
A genome-wide analysis of annexins from parasitic organisms and their vectors
- Cinzia Cantacessi
- , Jennifer M. Seddon
- , Terrence L. Miller
- , Chiuan Yee Leow
- , Laëtitia Thomas
- , Lyndel Mason
- , Charlene Willis
- , Giselle Walker
- , Alex Loukas
- , Robin B. Gasser
- , Malcolm K. Jones
- & Andreas Hofmann
Scientific Reports 3 , 1–8

Rights & permissionsfor article A genome-wide analysis of annexins from parasitic organisms and their vectors . Opens in a new window.
Research | 19 January 2014 | Open
Genome of the human hookworm Necator americanus
- Yat T Tang
- , Xin Gao
- , Bruce A Rosa
- , Sahar Abubucker
- , Kymberlie Hallsworth-Pepin
- , John Martin
- , Rahul Tyagi
- , Esley Heizer
- , Xu Zhang
- , Veena Bhonagiri-Palsikar
- , Patrick Minx
- , Wesley C Warren
- , Qi Wang
- , Bin Zhan
- , Peter J Hotez
- , Paul W Sternberg
- , Annette Dougall
- , Soraya Torres Gaze
- , Jason Mulvenna
- , Javier Sotillo
- , Shoba Ranganathan
- , Elida M Rabelo
- , Richard K Wilson
- , Philip L Felgner
- , Jeffrey Bethony
- , John M Hawdon
- , Robin B Gasser
- , Alex Loukas
- & Makedonka Mitreva
Nature Genetics 46 , 261–269

Rights & permissionsfor article Genome of the human hookworm Necator americanus . Opens in a new window.
Research | 15 January 2012 | Open
Whole-genome sequence of Schistosoma haematobium
- Neil D Young
- , Aaron R Jex
- , Bo Li
- , Shiping Liu
- , Linfeng Yang
- , Zijun Xiong
- , Yingrui Li
- , Cinzia Cantacessi
- , Ross S Hall
- , Xun Xu
- , Fangyuan Chen
- , Xuan Wu
- , Adhemar Zerlotini
- , Guilherme Oliveira
- , Andreas Hofmann
- , Guojie Zhang
- , Xiaodong Fang
- , Yi Kang
- , Bronwyn E Campbell
- , Alex Loukas
- , Shoba Ranganathan
- , David Rollinson
- , Gabriel Rinaldi
- , Paul J Brindley
- , Huanming Yang
- , Jun Wang
- , Jian Wang
- & Robin B Gasser
Nature Genetics 44 , 221–225

Rights & permissionsfor article Whole-genome sequence of Schistosoma haematobium . Opens in a new window.
Reviews | 15 October 2010
Developing vaccines to combat hookworm infection and intestinal schistosomiasis
Nature Reviews Microbiology 8 , 814–826

Rights & permissionsfor article Developing vaccines to combat hookworm infection and intestinal schistosomiasis . Opens in a new window.

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The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation

Changes in duodenal tissue-associated microbiota following hookworm infection and consecutive gluten challenges in humans with coeliac disease

Diterpenoid alkaloids of Aconitum laciniatum and mitigation of inflammation by 14-O-acetylneoline in a murine model of ulcerative colitis

Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects

New drugs for an ancient parasite

Tetraspanins on the surface of Schistosoma mansoni are protective antigens against schistosomiasis

Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes

Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing

Elevated prevalence of Helicobacter species and virulence factors in opisthorchiasis and associated hepatobiliary disease

Hookworm infection

Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms

Changes in protein expression after treatment with Ancylostoma caninum excretory/secretory products in a mouse model of colitis

A genome-wide analysis of annexins from parasitic organisms and their vectors

Genome of the human hookworm Necator americanus

Whole-genome sequence of Schistosoma haematobium

Developing vaccines to combat hookworm infection and intestinal schistosomiasis

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