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News and Views | 7 November 2012
Waking up HSCs: a new role for E-selectin
- Malcolm A S Moore
Nature Medicine 18 , 1613–1614

Rights & permissionsfor article Waking up HSCs: a new role for E-selectin . Opens in a new window.
Research | 30 May 1970
Two Dimensional Cell Separation: Comparison of Embryonic and Adult Haemopoietic Stem Cells
- J. S. HASKILL
- & M. A. S. MOORE
Nature 226 , 853–854

Rights & permissionsfor article Two Dimensional Cell Separation: Comparison of Embryonic and Adult Haemopoietic Stem Cells . Opens in a new window.
1 April 1999
Expression of Telomerase after Retroviral Transduction Increases Lifespan of Primary Human Fibroblasts
- Sonia Franco
- , Karen L MacKenzie
- , Cuiwan Tan
- , Chad May
- , Michel Sadelain
- & Malcolm A S Moore
Pediatric Research 45 , 146–146

Rights & permissionsfor article Expression of Telomerase after Retroviral Transduction Increases Lifespan of Primary Human Fibroblasts . Opens in a new window.
News and Views | 1 September 2010
A cancer fate in the hands of a samurai
- Malcolm A S Moore
Nature Medicine 16 , 963–965

Rights & permissionsfor article A cancer fate in the hands of a samurai . Opens in a new window.
Research | 2 September 1967
Chromosome Marker Studies in the Irradiated Chick Embryo
- M. A. S. MOORE
- & J. J. T. OWEN
Nature 215 , 1081–1082

Rights & permissionsfor article Chromosome Marker Studies in the Irradiated Chick Embryo . Opens in a new window.
Research | 6 December 2016 | Open
EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia
- S Charmsaz
- , F Al-Ejeh
- , T M Yeadon
- , K J Miller
- , F M Smith
- , B W Stringer
- , A S Moore
- , F-T Lee
- , L T Cooper
- , C Stylianou
- , G T Yarranton
- , J Woronicz
- , A M Scott
- , M Lackmann
- & A W Boyd
Leukemia 31 , 1779–1787

Rights & permissionsfor article EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia . Opens in a new window.
Research | 25 December 1975
Role of stem cell migration in initiation of mouse foetal liver haemopoiesis
- G. R. JOHNSON
- & M. A. S. MOORE
Nature 258 , 726–728

Rights & permissionsfor article Role of stem cell migration in initiation of mouse foetal liver haemopoiesis . Opens in a new window.
Research | 17 July 1965
Chromosome Marker Studies in the Graft-versus-Host Reaction in the Chick Embryo
Nature 207 , 313–315

Rights & permissionsfor article Chromosome Marker Studies in the Graft-versus-Host Reaction in the Chick Embryo . Opens in a new window.
Research | 1 October 2000
Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4⁺ T cells
Nature Medicine 6 , 1154–1159

Rights & permissionsfor article Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4+ T cells . Opens in a new window.
Research | 29 September 1977
In vitro duplication and ‘cure’ of haemopoietic defects in genetically anaemic mice
- T. M. DEXTER
- & M. A. S. MOORE
Nature 269 , 412–414

Rights & permissionsfor article In vitro duplication and ‘cure’ of haemopoietic defects in genetically anaemic mice . Opens in a new window.
Research | 4 December 1965
Chromosome Marker Studies on the Development of the Haemopoietic System in the Chick Embryo
- M. A. S. MOORE
- & J. J. T. OWEN
Nature 208 , 956–956

Rights & permissionsfor article Chromosome Marker Studies on the Development of the Haemopoietic System in the Chick Embryo . Opens in a new window.
11 February 2010
Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias
- A S Moore
- , J Blagg
- , S Linardopoulos
- & A D J Pearson
Leukemia 24 , 671–678

Rights & permissionsfor article Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias . Opens in a new window.
1 June 1997
Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA
- Salvatore J. Cannizzo
- , Beat M. Frey
- , Shahin Raffi
- , Malcolm A.S. Moore
- , Dan Eaton
- , Motoyoshi Suzuki
- , Ravi Singh
- , Charles A. Mack
- & Ronald G. Crystal
Nature Biotechnology 15 , 570–573

Rights & permissionsfor article Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA . Opens in a new window.
Research | 1 April 1977
Report of a workshop on standardization of selective cultures for normal and leukaemic cells
- M A S Moore
- , A W Burgess
- , D Metcalf
- , E A McCulloch
- , W A Robinson
- , K A Dicke
- , P A Chervenick
- , J M Bull
- , A M Wu
- , E R Stanley
- , J Goldman
- & N Testa
British Journal of Cancer 35 , 500–508

Rights & permissionsfor article Report of a workshop on standardization of selective cultures for normal and leukaemic cells . Opens in a new window.
Research | 22 February 2012
Selective FLT3 inhibition of FLT3-ITD⁺ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns
- A S Moore
- , A Faisal
- , D Gonzalez de Castro
- , V Bavetsias
- , C Sun
- , B Atrash
- , M Valenti
- , A de Haven Brandon
- , S Avery
- , D Mair
- , F Mirabella
- , J Swansbury
- , A D J Pearson
- , P Workman
- , J Blagg
- , F I Raynaud
- , S A Eccles
- & S Linardopoulos
Leukemia 26 , 1462–1470

Rights & permissionsfor article Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns . Opens in a new window.
Research | 13 July 2017 | Open
The MLL recombinome of acute leukemias in 2017
- C Meyer
- , T Burmeister
- , D Gröger
- , G Tsaur
- , L Fechina
- , A Renneville
- , R Sutton
- , N C Venn
- , M Emerenciano
- , M S Pombo-de-Oliveira
- , C Barbieri Blunck
- , B Almeida Lopes
- , J Zuna
- , J Trka
- , P Ballerini
- , H Lapillonne
- , M De Braekeleer
- , G Cazzaniga
- , L Corral Abascal
- , V H J van der Velden
- , E Delabesse
- , T S Park
- , S H Oh
- , M L M Silva
- , T Lund-Aho
- , V Juvonen
- , A S Moore
- , O Heidenreich
- , J Vormoor
- , E Zerkalenkova
- , Y Olshanskaya
- , C Bueno
- , P Menendez
- , A Teigler-Schlegel
- , U zur Stadt
- , J Lentes
- , G Göhring
- , A Kustanovich
- , O Aleinikova
- , B W Schäfer
- , S Kubetzko
- , H O Madsen
- , B Gruhn
- , X Duarte
- , P Gameiro
- , E Lippert
- , A Bidet
- , J M Cayuela
- , E Clappier
- , C N Alonso
- , C M Zwaan
- , M M van den Heuvel-Eibrink
- , S Izraeli
- , L Trakhtenbrot
- , P Archer
- , J Hancock
- , A Möricke
- , J Alten
- , M Schrappe
- , M Stanulla
- , S Strehl
- , A Attarbaschi
- , M Dworzak
- , O A Haas
- , R Panzer-Grümayer
- , L Sedék
- , T Szczepański
- , A Caye
- , L Suarez
- , H Cavé
- & R Marschalek
Leukemia 32 , 273–284

Rights & permissionsfor article The MLL recombinome of acute leukemias in 2017 . Opens in a new window.
Research | 27 October 2013
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells
- Kimberly A Hartwell
- , Peter G Miller
- , Siddhartha Mukherjee
- , Alissa R Kahn
- , Alison L Stewart
- , David J Logan
- , Joseph M Negri
- , Mildred Duvet
- , Marcus Järås
- , Rishi Puram
- , Vlado Dancik
- , Fatima Al-Shahrour
- , Thomas Kindler
- , Zuzana Tothova
- , Shrikanta Chattopadhyay
- , Thomas Hasaka
- , Rajiv Narayan
- , Mingji Dai
- , Christina Huang
- , Sebastian Shterental
- , Lisa P Chu
- , J Erika Haydu
- , Jae Hung Shieh
- , David P Steensma
- , Benito Munoz
- , Joshua A Bittker
- , Alykhan F Shamji
- , Paul A Clemons
- , Nicola J Tolliday
- , Anne E Carpenter
- , D Gary Gilliland
- , Andrew M Stern
- , Malcolm A S Moore
- , David T Scadden
- , Stuart L Schreiber
- , Benjamin L Ebert
- & Todd R Golub
Nature Chemical Biology 9 , 840–848

Rights & permissionsfor article Niche-based screening identifies small-molecule inhibitors of leukemia stem cells . Opens in a new window.
8 April 2013
Novel therapies for children with acute myeloid leukaemia
- A S Moore
- , P R Kearns
- , S Knapper
- , A D J Pearson
- & C M Zwaan
Leukemia 27 , 1451–1460

Rights & permissionsfor article Novel therapies for children with acute myeloid leukaemia . Opens in a new window.
12 February 2004
Expression of constitutively active Notch4 (Int-3) modulates myeloid proliferation and differentiation and promotes expansion of hematopoietic progenitors
- Q Ye
- , J-H Shieh
- , G Morrone
- & M A S Moore
Leukemia 18 , 777–787

Rights & permissionsfor article Expression of constitutively active Notch4 (Int-3) modulates myeloid proliferation and differentiation and promotes expansion of hematopoietic progenitors . Opens in a new window.
18 February 2003
Telomere dynamics in childhood leukemia and solid tumors: a follow-up study
- S Franco
- , M F Ozkaynak
- , C Sandoval
- , O Tugal
- , S Jayabose
- , M Engelhardt
- & M A S Moore
Leukemia 17 , 401–410

Rights & permissionsfor article Telomere dynamics in childhood leukemia and solid tumors: a follow-up study . Opens in a new window.
Research | 7 May 2007
Generation of functional hemangioblasts from human embryonic stem cells
- Shi-Jiang Lu
- , Qiang Feng
- , Sergio Caballero
- , Yu Chen
- , Malcolm A S Moore
- , Maria B Grant
- & Robert Lanza
Nature Methods 4 , 501–509

Rights & permissionsfor article Generation of functional hemangioblasts from human embryonic stem cells . Opens in a new window.
Research | 1 November 2001
Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth
- David Lyden
- , Koichi Hattori
- , Sergio Dias
- , Carla Costa
- , Pamela Blaikie
- , Linda Butros
- , Amy Chadburn
- , Beate Heissig
- , Willy Marks
- , Larry Witte
- , Yan Wu
- , Daniel Hicklin
- , Zhenping Zhu
- , Neil R. Hackett
- , Ronald G. Crystal
- , Malcolm A.S. Moore
- , Katherine A. Hajjar
- , Katia Manova
- , Robert Benezra
- & Shahin Rafii
Nature Medicine 7 , 1194–1201

Rights & permissionsfor article Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth . Opens in a new window.
14 June 2002
Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras
- Karen L MacKenzie
- , Sonia Franco
- , Afzal J Naiyer
- , Chad May
- , Michel Sadelain
- , Shahin Rafii
- & Malcolm A S Moore
Oncogene 21 , 4200–4211

Rights & permissionsfor article Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras . Opens in a new window.
Research | 24 February 2013
Nrf2 regulates haematopoietic stem cell function
- Jennifer J. Tsai
- , Jarrod A. Dudakov
- , Koichi Takahashi
- , Jae-Hung Shieh
- , Enrico Velardi
- , Amanda M. Holland
- , Natalie V. Singer
- , Mallory L. West
- , Odette M. Smith
- , Lauren F. Young
- , Yusuke Shono
- , Arnab Ghosh
- , Alan M. Hanash
- , Hien T. Tran
- , Malcolm A. S. Moore
- & Marcel R. M. van den Brink
Nature Cell Biology 15 , 309–316

Rights & permissionsfor article Nrf2 regulates haematopoietic stem cell function . Opens in a new window.
Research | 21 September 2003
Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice
- Tiziano Barberi
- , Peter Klivenyi
- , Noel Y Calingasan
- , Hyojin Lee
- , Hibiki Kawamata
- , Kathleen Loonam
- , Anselme L Perrier
- , Juan Bruses
- , Maria E Rubio
- , Norbert Topf
- , Viviane Tabar
- , Neil L Harrison
- , M Flint Beal
- , Malcolm A S Moore
- & Lorenz Studer
Nature Biotechnology 21 , 1200–1207

Rights & permissionsfor article Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice . Opens in a new window.
Research | 1 July 2002
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1⁺ stem cells from bone-marrow microenvironment
- Koichi Hattori
- , Beate Heissig
- , Yan Wu
- , Sergio Dias
- , Rafael Tejada
- , Barbara Ferris
- , Daniel J. Hicklin
- , Zhenping Zhu
- , Peter Bohlen
- , Larry Witte
- , Jan Hendrikx
- , Neil R. Hackett
- , Ronald G. Crystal
- , Malcolm A.S. Moore
- , Zena Werb
- , David Lyden
- & Shahin Rafii
Nature Medicine 8 , 841–849

Rights & permissionsfor article Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1+ stem cells from bone-marrow microenvironment . Opens in a new window.

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Waking up HSCs: a new role for E-selectin

Two Dimensional Cell Separation: Comparison of Embryonic and Adult Haemopoietic Stem Cells

Expression of Telomerase after Retroviral Transduction Increases Lifespan of Primary Human Fibroblasts

A cancer fate in the hands of a samurai

Chromosome Marker Studies in the Irradiated Chick Embryo

EphA3 as a target for antibody immunotherapy in acute lymphoblastic leukemia

Role of stem cell migration in initiation of mouse foetal liver haemopoiesis

Chromosome Marker Studies in the Graft-versus-Host Reaction in the Chick Embryo

Dendritic cells genetically modified to express CD40 ligand and pulsed with antigen can initiate antigen-specific humoral immunity independent of CD4⁺ T cells

In vitro duplication and ‘cure’ of haemopoietic defects in genetically anaemic mice

Chromosome Marker Studies on the Development of the Haemopoietic System in the Chick Embryo

Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias

Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA

Report of a workshop on standardization of selective cultures for normal and leukaemic cells

Selective FLT3 inhibition of FLT3-ITD⁺ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

The MLL recombinome of acute leukemias in 2017

Niche-based screening identifies small-molecule inhibitors of leukemia stem cells

Novel therapies for children with acute myeloid leukaemia

Expression of constitutively active Notch4 (Int-3) modulates myeloid proliferation and differentiation and promotes expansion of hematopoietic progenitors

Telomere dynamics in childhood leukemia and solid tumors: a follow-up study

Generation of functional hemangioblasts from human embryonic stem cells

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

Multiple stages of malignant transformation of human endothelial cells modelled by co-expression of telomerase reverse transcriptase, SV40 T antigen and oncogenic N-ras

Nrf2 regulates haematopoietic stem cell function

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice

Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1⁺ stem cells from bone-marrow microenvironment

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