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Matthew Rasband: Lead Editor
Matthew Rasband is a member of the Cell Biology Editorial Board and Lead Editor of the Cell Communication Topic Room.
This content is currently under construction.
Explore Genetics
Gene Inheritance and Transmission
Transmission genetics is the study of how genes are passed from one generation to the next, and was a primary focus for early geneticists. The articles in this Subject space help you explore a wide range of topics in classical genetics. They also illustrate how the analytical power of gene inheritance combined with modern molecular approaches help us understand some of the most complex problems in genetics.
Nucleic Acid Structure and Function
The articles in this Subject space describe the science surrounding the structure and function of DNA. Here, you will find information on the chemical structure of DNA; organization of DNA into chromosomes, genes, and gene families; the processes of DNA replication, transcription, and translation; as well techniques related to manipulation of the genetic sequence.
Evolutionary Genetics
Evolutionary genetics examines the genetic relationships among groups of organisms and how changes in their genes shape the patterns of evolution and biodiversity. The articles in this Subject space focus on five main areas: phylogenetics; mutation and molecular population genetics; the genetics of speciation; genome evolution; and evolution & development.
Genomics
A genome is an organism's complete set of genetic material. Thus, genomics is study genetics on a large scale, including information about vast numbers of genes and DNA sequences from scores of organisms. The articles in this Subject space explore genomics-based methods for the study of genetic variation, the value of genomic data, and, of course, the politics surrounding the uses of genomic data.
Genetics and Society
This topic room covers the ethical, legal, and social implications (ELSI) of genetic advances and their applications. To lay a foundation for ELSI discussions, the collection of articles in this Subject space explore the unique medical, ethical and legal issues encountered in genetic diseases, and the profound impact genetic conditions have at the individual, family, and societal levels.
Gene Expression and Regulation
Gene expression and regulation describes the process by which information encoded in an organism's DNA directs the synthesis of end products, RNA or protein. The articles in this Subject space help you explore the vast array of molecular and cellular processes and environmental factors that impact the expression of an organism's genetic blueprint.
Chromosomes and Cytogenetics
Cytogenetics is the study of chromosomes and their role in heredity. The articles in this Subject space provide rich information on chromosome structure and composition, the methods that scientists use to analyze chromosomes, chromosome abnormalities associated with disease, the roles that chromosomes play in sex determination, and changes in chromosomes during evolution.
Population and Quantitative Genetics
Population and quantitative genetics collectively focus on the genetic basis of variation among the individuals in a population. Population genetics focuses on allele and genotype frequencies, whereas quantitative genetics focuses on the ways that variation in genotype and environment contribute to variance in phenotype among individuals. The articles in this Subject space address both subjects.
Genes and Disease
Understanding the role of genetics in disease has become a central part of medical research. As such, the articles in this Subject space explore the complex relationship between human genetics and various disease states. This room examines current medical research and tools targeting these conditions in the effort to better treat or prevent them.
