Essentials of Genetics is a guided introduction to many key concepts in genetics, from DNA ...

Essentials of Genetics is a guided introduction to many key concepts in genetics, from DNA structure and function to population genetics. It provides an excellent reference for students or lifelong learners and can be a teaching tool for faculty, featuring high quality video-based visualizations of genetics processes, clear explanations, and links to advanced study resources.

Model organisms have long been valuable resources for mapping the genes responsible for specific ...

Model organisms have long been valuable resources for mapping the genes responsible for specific phenotypes. Today, with the help of entire genomic sequences, scientists are equipped with additional tools to help them map genes to chromosomes. How does this work? How has genome sequencing changed the landscape of gene mapping? How do we use model organisms, like zebrafish, to locate specific genes involved in human biology?

This eBook will take students through some of the seminal experiments in genetics, allowing ...

This eBook will take students through some of the seminal experiments in genetics, allowing students to review some of the data and literature that has provided us with our foundational understanding of our genetic material.

DNA to RNA to Protein: This is the Central Dogma, a term coined by Francis Crick in 1958. Since the ...

DNA to RNA to Protein: This is the Central Dogma, a term coined by Francis Crick in 1958. Since the discovery of the helical structure of DNA, scientists began to elucidate the value of that structure. The double helix provided both a template and storage mechanism. Mechanisms of transcription and translation take the information encoded in the DNA helix and make it "work" in cells, through the production of proteins defined by nucleic acid coding regions. Today, we know that the Central Dogma is much more complex.

Anyone interested in exploring protein-coding genes using the University of California Santa Cruz ...

Anyone interested in exploring protein-coding genes using the University of California Santa Cruz (UCSC) Genome Browser may use this guide as a starting point. Meant for all audiences, this eBook is a tutorial for those who have little or no experience or those advanced users who are not yet familiar with many of the gene-oriented browser features.

This series of articles reviews some important concepts about the X chromosome, such as sex ...

This series of articles reviews some important concepts about the X chromosome, such as sex determination, X-linkage and X-inactivation.

In eukaryotes, the tight or loose packaging of the genes in chromatin (DNA plus specific proteins) ...

In eukaryotes, the tight or loose packaging of the genes in chromatin (DNA plus specific proteins) can control whether the genes can be expressed to form their encoded product. Chromatin is usually not "permissive" but it can be modified in specific areas to open it up for transcription of the genes. Chromatin is opened by remodeling complexes. Nucleosomes, eight histone molecules plus associate DNA of about 140 nucleotides in length, can be "closed" by removing acetyl groups on the tails of the histones, or "opened" by placing acetyl groups there. Placement of acetyl or methyl groups on a specific histone can have opposing effects or additive effects on gene expression. The gene expression effect of histone modification placements is called the histone code. DNA itself can be methylation and that also regulates gene expression, generally to turn off the gene.

Genes play a role in many human disorders. Some rare disorders are linked to mutations in single ...

Genes play a role in many human disorders. Some rare disorders are linked to mutations in single genes that follow Mendelian inheritance patterns. Other disorders are regulated by multiple genes, or multiple genes together with the environment. Still others are the result of chromosomal abnormalities.

This eBook will help you understand the ways that chromosomes are linked to some human diseases and ...

This eBook will help you understand the ways that chromosomes are linked to some human diseases and will discuss some of the techniques involved in studying chromosomes.

The Human Genome Project has revealed the entire sequence of nucleic acids, the As, Ts, Cs and Gs, ...

The Human Genome Project has revealed the entire sequence of nucleic acids, the As, Ts, Cs and Gs, in the genes of our species. However, the sequence alone actually tells us little about our biology. Now, scientists are examining this massively long sequence for clues about how variation in our genetic sequence contributes to disease.

This eBook takes students through our basic understanding of inheritance. Then we examine the ...

This eBook takes students through our basic understanding of inheritance. Then we examine the complexity of polygenic traits and phenotypes affected by environmental conditions. Finally we explore how scientists study the genetic component of certain phenotypes.

Genetic variation is the substrate of evolution. Examining the genetic differences between ...

Genetic variation is the substrate of evolution. Examining the genetic differences between individuals of the same species, as well as comparing the genomes of different species, can tell us a great deal about the relationships between organisms.

This group of readings will guide you through some of the major topics in genomics.

This group of readings will guide you through some of the major topics in genomics.

The sequencing of the human genome has changed how we do genetics. Instead of examining one gene at ...

The sequencing of the human genome has changed how we do genetics. Instead of examining one gene at a time, we now look at the genetic variation across the entire genome. We can examine how transcription changes at a global level in different cell types, or under different conditions. How do these methods that examine differences in "global" transcriptional, translational and epigenetic phenomena affect how we think about human genetics?

Testing for gene mutations that cause or predispose an individual to disease is not as ...

Testing for gene mutations that cause or predispose an individual to disease is not as straightforward as you might think. There are complex issues raised by how, where and when these tests are administered, as well as how the test result information can be used.

This group of readings starts with the basics about genetic inheritance, then delves more deeply ...

This group of readings starts with the basics about genetic inheritance, then delves more deeply into issues particular to the human species.

Finished ahead of schedule and under budget, the Human Genome Project (HGP) was a major scientific ...

Finished ahead of schedule and under budget, the Human Genome Project (HGP) was a major scientific enterprise that involved many different labs across the world. What have we learned with the HGP? Where are we going next?

This eBook includes some of our key pieces that examine prokaryotic genetics and the important ...

This eBook includes some of our key pieces that examine prokaryotic genetics and the important concepts we can learn by studying these organisms.

This eBook explores some of the fundamental techniques in molecular biology and biotechnology that ...

This eBook explores some of the fundamental techniques in molecular biology and biotechnology that allow scientists to manipulate genes and genomes. The content in this eBook also explores the ethical concerns of some of this technology.

Essentials of Cell Biology introduces readers to the core concepts of cell biology. It provides an ...

Essentials of Cell Biology introduces readers to the core concepts of cell biology. It provides an introduction for students of all ages and can be a springboard to more specialized topics for advanced students. It begins with a discussion of the fundamental properties of cells: the origin of the cell, how cells are organized, how they reproduce, and how they use energy. Other subjects include the cellular structures responsible for cell function, the signals that cells use to communicate with one another, and the intricate controls on cell division. At the end of each unit in this eBook there is the option to test your knowledge with twenty multiple-choice questions.

Cell Biology for Seminars introduces cell biology concepts and follows them with selected readings ...

Cell Biology for Seminars introduces cell biology concepts and follows them with selected readings from the Nature archive that deepen the learning experience. The book begins with a discussion of the fundamental properties of cells: the origin of the cell, how cells are organized, how they reproduce, and how they use energy. Other subjects include the cellular structures responsible for cell function, the signals that cells use to communicate with one another, and the intricate controls on cell division. At the end of each unit in this eBook there is the option to test your knowledge with 25 multiple-choice questions. This seminar edition of the Cell Biology eBook is meant for advanced students or seminar settings.

Infection rates of Dengue Fever-causing virus are on the rise in recent decades. The World Health ...

Infection rates of Dengue Fever-causing virus are on the rise in recent decades. The World Health Organization estimates the number of infections across the globe to be 50 million per year. As this debilitating and sometimes lethal infection affects more and more people every year, science research is on notice, and moving fast to catch up. In this eBook, you will learn the symptoms of dengue, how it spreads via mosquitoes, and what new research is emerging to stop the disease in its tracks.

Cancer is a genetic disease. Yet, it is rarely the result of an inherited mutation that ...

Cancer is a genetic disease. Yet, it is rarely the result of an inherited mutation that "runs" in a family. Instead, cancer generally arises from the accumulation of mutations in cells that cause excess cell division, and aberrant cell survival.

English Communication for Scientists is a brief guide on how to communicate more effectively in ...

English Communication for Scientists is a brief guide on how to communicate more effectively in English, no matter how much previous experience you have. Although it was developed with non-native speakers of English in mind, it should prove useful for native speakers, too. Created by seasoned communicators, English Communication for Scientists provides no-nonsense, directly applicable guidelines, illustrated with examples of written documents, oral presentations, and more.

The Guide to Life Science Careers helps you to explore and choose what career is best for you. ...

The Guide to Life Science Careers helps you to explore and choose what career is best for you. Interviews with professionals about how they chose their career paths are included so you can learn how others became successful and understand the positive and negative aspects of various career choices. Strategies for networking, overcoming shyness, and building your résumé are also discussed to help you lay the groundwork for success and present the best you to potential employers.