Troponin and tropomyosin regulate contraction via calcium binding
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Troponin and tropomyosin regulate contraction via calcium binding
Simplified schematic of actin backbones, shown as gray chains of actin molecules (balls), covered with smooth tropomyosin filaments. Troponin is shown in red (subunits not distinguished). Upon binding calcium, troponin moves tropomyosin away from the myosin-binding sites on actin (bottom), effectively unblocking it. Modified from Lehman et al. (1994).
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How do muscles contract? What molecules are necessary for a tissue to change its shape?
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