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The steps involved in making a knockout mouse.

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The steps involved in making a knockout mouse.
The steps involved in making a knockout mouse.

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Scientists Can Analyze Gene Function by Deleting Gene Sequences

There are at least thousands of genes in the DNA of most organisms, and more than 20,000 in the DNA of each human being, for instance. How can we determine which genes lead to which observable traits? Scientists have developed techniques that delete individual gene sequences from an organism’s DNA. By observing the impact of this deletion on the entire biological system of an organism, scientists can connect previously unknown genes to their function.

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Andrew Rayner 06/14/2016 If you don't have the resources to engineer your own knockout mice then Horizon Discovery can help work with your team to design a custom in vivo model to your specification. See https://www.horizondiscovery.com/in-vivo-models/sagespeed-custom-model-creation

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