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Structure of the Holliday junction.

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Structure of the Holliday junction.
(A) Electron-microscope image of a recombination intermediate. In this image, the Holliday junction was partially denatured to assist its visualization. (B) Two possible configurations for the Holliday junction, with the DNA shown in the parallel (left) or antiparallel configuration (right).

This image is linked to the following Scitable pages:

Genetic Recombination

How does DNA recombination work? It occurs frequently in many different cell types, and it has important implications for genomic integrity, evolution, and human disease.

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