Gear symbols represent the key "go/no-go" decisions for development of a pharmaceutical product. Boxes represent key activities or disciplines involved in the research necessary to answer the questions generated at each decision gate. Asking the right questions at the right time is the key to strategic drug development planning. ADME: absorption, distribution, metabolism, and excretion; GLP: good laboratory practice; PK: pharmacokinetics.
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There is a vital need for human subjects in research related to drug development, but can we properly balance the welfare of human research subjects with the need for experimental data?
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