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Germ cell development and associated epigenetic events in mice

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Germ cell development and associated epigenetic events in mice
Chronology of mouse germ cell development and the main epigenetic events that occur. PGCs (primordial germ cells) first emerge at embryonic day 7.25 (E7.25) as a cluster of about twenty cells. Subsequently, they rapidly proliferate with an average doubling time of approximately 16 hours. Before they stop dividing at E13.5, their number reaches up to about 26,000. MSCI, meiotic sex-chromosome inactivation.

This image is linked to the following Scitable pages:

Germ Cells and Epigenetics

The path of primordial germ cells illustrates the complexities of imprinted DNA, which contains epigenetic marks that turn on and off when necessary.

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