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Epigenetic diseases and their causes and symptoms.

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Epigenetic diseases and their causes and symptoms.
Epigenetic changes are responsible for human diseases, including Fragile X syndrome, Angelman’s syndrome, Prader-Willi syndrome, and various cancers. Abbreviations: ATR-X syndrome, alpha-thalassaemia, mental retardation syndrome, X linked; BWS, Beckwith–Wiedemann syndrome; CREB, cAMP-response-element-binding protein; HAT, histone acetyltransferase; HMT, histone methyltransferase; ICF, immunodeficiency, centromeric region instability and facial anomalies syndrome; UTR, untranslated region.

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The behavior of a person's genes doesn't just depend on the genes' DNA sequence - it's also affected by so-called epigenetic factors. Changes in these factors can play a critical role in disease.


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