Different cell types in the mammalian gut. The gut contains a mixture of differentiated cells and stem cells.

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Different cell types in the mammalian gut. The gut contains a mixture of differentiated cells and stem cells.

The (a) intestine, (b) esophagus and (c) stomach are shown. Quiescent stem cells (d) through asymmetric division probably give rise to more rapidly dividing active stem cells, which then produce progenitor cells, while losing their multipotency and ability to proliferate. All these progeny cells have defined positions in the different organs. To maintain its function and continue to produce new stem cells, the stem cell can divide into and produce more stem cells at the same position (symmetric division).

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Cell Differentiation and Tissue

The organized arrangement of cells in tissues relies on controlled cell division and cell death. Learn how cells are replenished by stem cells and removed by apoptosis.