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Cell division in Ascaris megalocephala bivalens, as drawn by Boveri in 1901.

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Cell division in Ascaris megalocephala bivalens, as drawn by Boveri in 1901.
This lithograph illustrates the high quality of the visualization techniques used in 1901 for documenting the cellular structures involved in cell division. The figure shows chromosomes in the middle of the dividing cell, as well as the spindle, two centrosomes, and two centrioles within each centrosome. Note that the cytoplasm is perceived as being structured.

This image is linked to the following Scitable pages:

Mitosis and Cell Division

The five phases of mitosis and cell division tightly coordinate the movements of hundreds of proteins. How did early biologists unravel this complex dance of chromosomes?

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