The image shows k-means clustering of four dietary profiles distinguished primarily by proportion of fat and carbohydrate intake. The data were used to study the relationship between diet and maternal and neonatal health. See article by Costanza et al. on page 1890.

Increased cell migration in familial Mediterranean fever (FMF) is due to the presence of more active pyrin inflammasomes, as shown in a study of wound healing in patients with FMF. See article by Akbaba et al. on page 1399.

The use of multimodal MRI measurements to distinguish acute bilirubin encephalopathy (ABE) from non-ABE in neonates with hyperbilirubinemia.See article by Miao et al. on page 1168.

Coronal MRI section of a baby with seizures (top) and one without (bottom). Cerebrospinal fluid is shown in pink, gray matter in green, white matter in blue, deep cortical nuclei in yellow, cerebellum in cyan. See article by Zachary et al. on page 955.

Variant R78P in BRAT1 does not affect the gene's ability to downregulate MitoSOX in mitochondria.See article by Li et al. on page 565.

Sepsis remains a major cause of morbidity and mortality in children. In this Annual Review Issue, we will explore basic mechanisms, diagnostic techniques, and interventions of this disorder.

Magnetic resonance spectroscopy at term of very-low-birthweight infants with delayed (top) and normal (bottom) development. See article by Tomiyasu et al. on page 197.