Abstract
Background: The pathogenesis of DHF is still unknown; ADE & virulency of dengue virus caused plasma leakage thrombocytopenia and haemorrhagic clinical manifestation of DHF cases; resuscitation fluid and increasing thrombocyte to prevent severity of Dengue Haemorrhagic cases.
The aim of study: To find the role of Psiidii guava leaf extract liquid in DHF cases.
Material & method: The study had been done at Dr. Soetomo hospital Surabaya, Hasan Sadikin hospital Bandung, and Dr. Cipto Mangunkusumo hospital Jakarta, on January 31, 2007 to February 01, 2008; 93 cases DHF were recruiting for study; 54 DHF cases grade 1 & 2 as study group. And 39 DHF cases grade 1 & 2 as control; study group got resuscitation fluid and Psiidii guava leaf extract liquid. Control group got resuscitation fluid and placebo. All cases were followed everyday until discharge by paediatrician in charge.
Based on increasing thrombocyte number, 54 cases of study showed 86,47 ± 86,23 and 93 cases of control group showed 32.807 ± 67,56 and based on grade of thrombocyte number 40 cases of study group showed increasing number of thrombocyte, and 7 decrease. 23 control groups were increase and 15 control group were decrease. The result showed significant differences p< 0,010.
Conclusion: Psiidii guava leaf extract could significantly increase thrombocyte in DHF cases.
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Soegijanto, S., Azhali, D., Tumbelaka, A. et al. 1254 The Role of Psidii Guava Leaf Extract to Increase Platelet Level in Dengue Virus Infection. Pediatr Res 68 (Suppl 1), 621 (2010). https://doi.org/10.1203/00006450-201011001-01254
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DOI: https://doi.org/10.1203/00006450-201011001-01254