Evolutions of precision radical polymerizations from metal-catalyzed radical addition: living polymerization, step-growth polymerization, and monomer sequence control

Evolutions of precision radical polymerizations from metal-catalyzed radical addition: living polymerization, step-growth polymerization, and monomer sequence control

Metal-catalyzed Kharasch addition or atom transfer radical addition enables metal-catalyzed living radical polymerization, step-growth radical polymerization



  • In comparison to the ubiquity of their chalcogenic thiophene analogs, selenophene-incorporated conjugated polymers are relatively scarce in the organic electronics literature. However, this scarcity belies the tremendous utility of selenophene in high-performance optoelectronic materials. In this focus review, we discuss the key developments in selenophene-based conjugated polymer research from the early polyselenophene investigations, through the detailed study of regioregular poly(3-hexylselenophene), to the state-of-the-art donor-acceptor polymers that have enabled advancements in the performance and functionality of various optoelectronic devices. Finally, we end with our perspective on the future of this field.

    • Adam V. Marsh
    • Martin Heeney
    Focus Review Open Access
  • The maintenance of stem cells multipotency and control of the differentiation direction are important for these applications in tissue engineering. We explored whether the multipotency of adipose derived stem cells (AdSCs) is maintained when they are removed from injectable polymer (IP) hydrogels with various degrees of cross-linking and induced to differentiate into osteoblasts and adipocytes. We confirmed that AdSCs cultured in IP hydrogels maintained an undifferentiated state. However, when cultured in an IP hydrogel, their multipotency was reduced.

    • Nozomi Mayumi
    • Nobuo Murase
    • Yuichi Ohya
    Original Article Open Access
  • This review outlines the research across the areas of polymer chemistry and cryobiology We discuss the solutions to problems in cryobiology from the viewpoint of polymeric materials science and the applications of polymer-based cryobiology for biomedical applications. We explain how the recent advances in polymer research have enabled the development of innovative polymeric cryoprotectants with novel mechanisms and the development of state-of-the-art methods for the intracellular delivery of substances, such as drugs, using a cryobiological technique called the freeze-concentration effect.

    • Kazuaki Matsumura
    • Robin Rajan
    • Sana Ahmed
    Focus Review Open Access
  • Recent advances in polymer informatics are reviewed, focusing on experimental research. Data-driven analyses, predictions, and suggestions are becoming more practical, despite the appropriate treatments of higher-order structures and process information acting as bottlenecks. After summarizing recent developments, future challenges in polymer informatics are discussed.

    • Kan Hatakeyama-Sato
    Focus Review
  • The effect of different types of maleic anhydride-modified polypropylene on interfacial shear strength for carbon fiber-reinforced polypropylene composites: The effect of three types of maleic anhydride-modified polypropylenes (MAPP) on the interfacial shear strength (IFSS) of PP and carbon fiber (CF) were investigated. The localization of MAPP at the interface enabled sufficient chemical interaction regardless of MA content of MAPP, and the differences of MA content had little IFSS dependences. When the chemical interaction is sufficient at the interface, the IFSS values were attributed to the crystallinity at the interphase, which depends on the natures such as crystallinity of MAPP added.

    • Ayaka Yamaguchi
    • Michio Urushisaki
    • Tamotsu Hashimoto
    Original Article
  • Tricoordinate boron embedded conjugated polymers, so-called p−π* conjugated polymers, have been studied as optoelectronic and sensor materials. p−π* Conjugated polymers usually possess bulky aryl groups that kinetically stabilize the boron centers, and the bulky aryl substituents prohibit intermolecular interactions in the solid state. In this work, we synthesized new p−π* conjugated polymers based on a thiophene-fused thiaborin unit. The thiaborin-based p−π* conjugated polymers exhibited great red shifts in the absorption spectra measured in film state relative to those measured in solution, suggesting strong intermolecular interactions.

    • Yohei Adachi
    • Mitsuru Sakabe
    • Joji Ohshita
    Original Article