Volume 31

  • No. 6 June 2024

    A proteomics atlas of citrullination

    Rebak et al. use proteomics to establish an expansive atlas of protein citrullination and implicate certain citrullinated sites as potentially clinically relevant in rheumatoid arthritis. Citrulline was initially discovered in watermelons.

    See Rebak et al.

  • No. 5 May 2024

    Mechanisms of RNA processing and splicing

    In this issue, we feature studies investigating RNA processing, including mechanisms of mRNA splicing, biogenesis of the splicing machinery, decoding of mRNA by the ribosome, and deadenylation of mRNA for degradation.

    See Editorial

  • No. 4 April 2024

    Disentangling channel-gating mechanisms

    Kalienkova et al. report high-resolution structures of an FMRFamide-gated sodium channel in several functional states. This disentangles the molecular basis by which different invertebrate receptors recognize similar neuropeptides and paves the way for studies of channel gating and ion conduction among the degenerin/epithelial sodium channel superfamily.

    See Kalienkova et al.

  • No. 3 March 2024

    Insights into mitochondrial DNA packaging

    A study by Isaac et al. presents mtFiber-seq, a method that measures individual mitochondrial genome packaging at nucleotide resolution, providing insight into the architecture of mitochondrial DNA packaging.

    See Isaac et al.

  • No. 2 February 2024

    Understanding writers and readers of ubiquitylation

    In this issue, we feature seven studies that progress our understanding of writers and readers of ubiquitylation, in addition to a Historical Perspective and several Comment pieces reflecting on the ever-expanding roles of this critical modification.

    See Editorial

  • No. 1 January 2024

    NSMB’s 30th anniversary

    To celebrate Nature Structural & Molecular Biology’s 30th anniversary, our cover features original artwork that was submitted by our reader Pedro Rebelo-Guiomar for our cover competition.

    See Rebelo-Guiomar and Editorial