Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Volume 26 Issue 2, February 2019

RPA in action

Bulk and single-molecule fluorescence analyses reveal the dynamics of RPA DNA-binding domains during homologous recombination.

See Pokhrel, Caldwell et al. 26, 129–136 (2019)

Image: Xuanyu Han/Moment/Getty. Cover Design: Erin Dewalt


Top of page ⤴

News & Views

  • Structural information on the respiratory supercomplex III2IV2 from budding yeast and from Mycobacterium smegmatis has become available, with cryo-EM work from four different groups.

    • Joana S. Sousa
    • Janet Vonck
    News & Views
  • A growing body of evidence suggests that cotranslational folding occurs from bacteria to mammalian cells, in particular for multi-domain proteins. In the assembly of yeast proteasomes, the initial interaction of Rpt1 and Rpt2 subunits has been found to take place on the translating ribosomes, coordinated by elongation pausing and involving the formation of Not1-containing compartments.

    • Xiao-Min Liu
    • Shu-Bing Qian
    News & Views
Top of page ⤴

Meeting Reports

  • The Ninth International Conference on the Hsp90 Chaperone Machine concluded in October 2018, in Leysin, Switzerland. The program highlighted findings in various areas, including integrated insights into the molecular mechanism of Hsp90, cochaperones, and clients’ structure and function.

    • Laura J. Blair
    • Olivier Genest
    • Mehdi Mollapour
    Meeting Report
Top of page ⤴


Top of page ⤴

Amendments & Corrections

Top of page ⤴


Quick links