Mapping uncharted waters in antibiotic-ribosome interactions

Mapping uncharted waters in antibiotic-ribosome interactions

Paternoga et al. present high-resolution structures of 17 antibiotics bound to E.coli ribosomes, thus unveiling conserved antibiotic binding to the ribosome, including ordered water molecules.

  • Helge Paternoga
  • Caillan Crowe-McAuliffe
  • Daniel N. Wilson


  • The 2021 Nobel Prize in Physiology or Medicine was awarded to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch." Their research identified transient receptor potential (TRP) and PIEZO ion channels as the proteins that sense these ubiquitous stimuli. To celebrate the award Nature Portfolio presents a Collection of articles on the topic.

  • Genome editing has great potential to change how we model, understand, and treat diseases. The Somatic Cell Genome Editing Consortium brings together investigators from 33 institutions to accelerate the development of editing tools, animal models, delivery approaches and therapeutic applications of genome editing.

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