Regulation of Cas7-11 by TPR-CHAT

Regulation of Cas7-11 by TPR-CHAT

The CRISPR-guided nuclease Cas7-11 forms a bird-like Craspase complex with the regulatory protease TPR-CHAT.

  • Babatunde Ekundayo
  • Davide Torre
  • Dongchun Ni
Brief Communication


  • The 2021 Nobel Prize in Physiology or Medicine was awarded to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch." Their research identified transient receptor potential (TRP) and PIEZO ion channels as the proteins that sense these ubiquitous stimuli. To celebrate the award Nature Portfolio presents a Collection of articles on the topic.

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