Starting clean intermittent catheterization (CIC) early does not provide any benefits with regard to renal abnormalities on dimercaptosuccinic acid (DMSA) scan in children with spinal dysraphism. Woo et al. retrospectively reviewed 100 children with spinal defects; 17 underwent CIC from birth and 83 started CIC at a median age of 5 years. Multivariate analysis demonstrated that initiation of CIC at birth was significantly associated with an increased risk of renal cortical loss on DMSA scan, along with a history of vesicoureteral reflux or hydronephrosis.
ORIGINAL RESEARCH PAPER
Woo, J. et al. Early clean intermittent catheterization may not prevent dimercaptosuccinic acid renal scan abnormalities in children with spinal dysraphism. J. Pediatr. Urol. doi:10.1016/j.jpurol.2013.09.001
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Preventing renal damage in children with spinal dysraphism. Nat Rev Urol 10, 618 (2013). https://doi.org/10.1038/nrurol.2013.243
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DOI: https://doi.org/10.1038/nrurol.2013.243