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Hollenbeck and Montie discuss the potential benefits and pitfalls of early extirpative surgery for T1 bladder cancer. The authors identify risk factors that, in their opinion, should prompt clinicians to consider radical cystectomy rather than a more conservative regimen of resection, chemotherapy and immunotherapy.
Diagnosis and treatment of chronic prostatitis are presently based on unsupported assumptions and a nonvalidated classification scheme. Here, Richard Alexander summarizes research by the Chronic Prostatitis Collaborative Research Network that challenges the assumptions and indicates that ongoing empiric administration of antimicrobial drugs to men with long-standing prostatitis should be abandoned.
