Clinical trials in rheumatology, similar to other areas of research, are associated with a plethora of ethical issues. Relevant issues, depending on the type of trial (for example, early phase trials, prevention trials and postmarketing studies), are outlined in this article, along with issues related to the selection of control arms for clinical trials, the selection of relevant outcome measures and some of the challenges in obtaining informed consent.
- Jeremy Sugarman
- Clifton O Bingham III