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  • Year in Review
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Regenerative medicine in 2012

The coming of age of musculoskeletal tissue engineering

Nature Reviews Rheumatology volume 9, pages 74–76 (2013)Cite this article

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Tissue engineering and regenerative medicine have advanced rapidly towards the development of therapeutic solutions for musculoskeletal disorders. In 2012, breakthroughs have been made in the guidance of adult stem cell homing, the tissue regenerative activity of stem-cell-derived extracellular matrix has been tested, and novel, mechanically superior biomaterials have been fabricated.

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Figure 1: New approaches to enhance MSC-mediated tissue repair.

Change history

  • 22 January 2013

    In the PDF version of this article initially published online the publication year was incorrect. This should have been 2013. The error has been corrected for the PDF version of the article.

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Acknowledgements

The work of the author is supported in part by grants from the Commonwealth of Pennsylvania Department of Health (SAP 4100050913), the NIH (NS080758) and the US Department of Defense (W81XWH-10-1-0850).

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  1. Department of Orthopaedic Surgery, Center for Cellular and Molecular Engineering, University of Pittsburgh School of Medicine, 450 Technology Drive, Room 221, Pittsburgh, 15219, PA, USA

    Rocky S. Tuan

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Tuan, R. The coming of age of musculoskeletal tissue engineering. Nat Rev Rheumatol 9, 74–76 (2013). https://doi.org/10.1038/nrrheum.2012.235

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